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Tytuł:
Statistical analysis of diabetes mellitus
Autorzy:
Drygas, Hilmar
Powiązania:
https://bibliotekanauki.pl/articles/729654.pdf
Data publikacji:
2009
Wydawca:
Uniwersytet Zielonogórski. Wydział Matematyki, Informatyki i Ekonometrii
Tematy:
Gram-Schmidt orthogonalization
regression model
Gauss-Markov theorem
least squares
diabetes mellitus
glucosis
antidiabetica
Opis:
This paper deals with an application of regression analysis to the regulation of the blood-sugar under diabetes mellitus. Section 2 gives a description of Gram-Schmidt orthogonalization, while Section 3 discusses the difference between Gauss-Markov estimation and Least Squares Estimation. Section 4 is devoted to the statistical analysis of the blood-sugar during the night. The response change of blood-sugar is explained by three variables: time, food and physical activity ("Bewegung"). At the beginning of the section it is shown that the proposed method was very successful in 2007.
Źródło:
Discussiones Mathematicae Probability and Statistics; 2009, 29, 1; 69-90
1509-9423
Pojawia się w:
Discussiones Mathematicae Probability and Statistics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
What next for diabetes mellitus?
Autorzy:
Witek, Bożena
Rochon-Szmejchel, Danuta
Kamińska, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/472510.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Pedagogiczny im. Komisji Edukacji Narodowej w Krakowie
Tematy:
diabetes
insulin
glucagon
Źródło:
Annales Universitatis Paedagogicae Cracoviensis. Studia ad Didacticam Biologiae Pertinentia; 2016, VI; 6-19
2083-7267
2450-3487
Pojawia się w:
Annales Universitatis Paedagogicae Cracoviensis. Studia ad Didacticam Biologiae Pertinentia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acute cholecystitis in patients with diabetes mellitus - systematic review
Autorzy:
Łącka, Monika
Spychalski, Piotr
Dobrzycka, Małgorzata
Rostkowska, Olga
Kobiela, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/895729.pdf
Data publikacji:
2020-01-09
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
complications
Diabetes Mellitus
Cholecystitis
course of hospitalization
Opis:
Introduction: According to the WHO, an estimated 422 million people are suffering from diabetes worldwide. Among them, the incidence of cholelithiasis is higher than in the healthy population. The aim of this literature review was to summarize the available evidence about acute cholecystitis in patients with diabetes. Materials and methods: This study adhered to the PRISMA guidelines. The course of hospitalization of patients with and without diabetes who underwent cholecystectomy due to acute cholecystitis was compared. Following information was abstracted from original studies: general study information, patient characteristics, complications, and recommendations for patients with diabetes. Results: Initial search provided 1632 results. After full text assessment, 40 studies met the inclusions criteria. Operative and postoperative complication rates were significantly higher among the diabetic patients. Diabetes is a risk factor for conversion from laparoscopic to open cholecystectomy method. The authors' opinions on elective surgery before the onset of acute cholecystitis symptoms are divided. Conclusions: Diabetic patients are at greater risk of developing complications. An individualized screening and treatment approach, as well as proper preparation of the diabetic patient for an elective cholecystectomy could have a positive effect on the outcome. However, the low quality of the data from the systematic review does not allow for meta-analysis, which is why we cannot draw strong conclusions.
Źródło:
European Journal of Translational and Clinical Medicine; 2019, 2, 2; 71-79
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zaburzenia przedsionkowe w cukrzycy
Vestibular dysfunction in diabetes mellitus
Autorzy:
Narożny, Waldemar
Powiązania:
https://bibliotekanauki.pl/articles/1033353.pdf
Data publikacji:
2017
Wydawca:
Oficyna Wydawnicza Mediton
Tematy:
badania kliniczne
cukrzyca
histopatologia
przedsionek
ucho wewnętrzne
zaburzenia przedsionkowe
Opis:
Diabetes is a metabolic disease characterised by hyperglicemia (increased glucose levels in blood) which occurs as a result of production or activity defect of beta cells in pancreas. Longlasting diabetes leads to serious complications which affect many organs, mainly organs of vision (microvasculature of the retina, cataract, blindness), kidneys (nephropathy), autonomic nervous system (polyneuropathy, neuropathy). Among organs less often affected by diabetic complications is inner ear (hearing loss, vestibular disorders). The author analysed the available literature on research on the impact of diabetes on the balance system carried out based on the animal model, human temporal bone and human studies. Results of clinical research devoted to this issue presented in 11 publications dated between 1990 and 2017 were part of the conducted analysis. Analyzed results of experimental and clinical research of the vestibular system indicate that both among animals and humans with diabetes there occurs a defect of peripheral and central part of the vestibular system. Within maculae of the saccule a degeneration of type I hair cells, lower density of type I hair cells, overproduction of extracellular matrix, dislodgement of otoconia fragments from maculae of the utricle and saccule surface to the posterior and lateral semicircular canals has been noted. Within the vestibular nerve a significant damage or thinning of the myelin sheath and smaller axonal fiber diameters have been noted. Clinical research confirmed presence of vestibular disorders in patients with diabetes. Their extensity and frequency was dependent on the duration of the illness, accompanying diseases and type of diabetes.
Cukrzyca jest chorobą metaboliczną charakteryzującą się hiperglikemią (podwyższonym poziomem glukozy we krwi) wynikającą z defektu produkcji lub działania insuliny wydzielanej przez komórki β trzustki. Wieloletnia cukrzyca prowadzi do groźnych powikłań, które dotyczą wielu narządów, głównie narządu wzroku (retinopatia cukrzycowa, zaćma, ślepota), nerek (cukrzycowa choroba nerek), autonomicznego układu nerwowego (polineuropatia, neuropatia). Do narządów rzadziej dotykanych powikłaniami cukrzycowymi należy ucho wewnętrzne (niedosłuch, zaburzenia przedsionkowe). Autor dokonał przeglądu dostępnego piśmiennictwa poświę- conego badaniom nad wpływem cukrzycy na stan narządu równowagi prowadzonym na modelu zwierzęcym, ludzkich kościach skroniowych oraz u ludzi. Analizie poddano wyniki badań klinicznych poświęconych temu zagadnieniu, przedstawione w 11 publikacjach z lat 1990-2017. Wyniki badań doświadczalnych i klinicznych narządu przedsionkowego wskazują na obecność u zwierząt i ludzi z cukrzycą uszkodzeń zarówno w części obwodowej, jak i ośrodkowej narządu przedsionkowego. W obrębie plamek zmysłowych woreczka stwierdzano uszkodzenie komórek rzęskowych (włosowatych) typu 1, zmniejszenie gęstości ich cytoplazmy, nadmiar macierzy międzykomórkowej, przemieszczanie się otolitów z powierzchni plamek zmysłowych do kanałów półkolistych. W obrębie nerwu przedsionkowego obserwowano znaczne uszkodzenie lub ścieńczenie otoczki mielinowej tego nerwu oraz skrócenie jego aksonów. Badania kliniczne potwierdziły obecność zaburzeń przedsionkowych u chorych z cukrzycą, których rozległość i nasilenie były zależne od czasu trwania choroby, schorzeń towarzyszących oraz postaci cukrzycy.
Źródło:
Otorynolaryngologia - przegląd kliniczny; 2017, 16, 4; 143-149
1643-658X
Pojawia się w:
Otorynolaryngologia - przegląd kliniczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Physical activity in type 2 diabetes mellitus: a review
Autorzy:
Burooj, Ahmed
Powiązania:
https://bibliotekanauki.pl/articles/33777868.pdf
Data publikacji:
2024-04-10
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
T2DM
Exercise
Diabetes
Diabetes Mellitus
Physical Activity
Opis:
Introduction This literature review explores the role of physical activity (PA) in managing and preventing type 2 diabetes mellitus (T2DM), synthesizing the latest guidelines for all T2DM patients. Following PRISMA guidelines, it identifies specific areas for further research. Material and Methods Indexing services (PubMed and Scopus) were used to identify relevant studies, emphasizing original research, review articles, and updated institutional guidelines spanning 2017-2023. The following keywords were used: diabetes, physical activity, type 2 diabetes mellitus, PA, and exercise. Proposal and opinion articles, non-English papers (or those lacking full-text translation), studies involving non-human subjects, pediatric populations or with skewed gender distribution were excluded. Results PA improves quality of life, BMI, glycemic control and well-being. Effects vary by activity domain, such as work or leisure time. Recommendations suggest 60 daily minutes of exercise for children, 150 weekly minutes of moderate intensity exercise for adults, and screening for adverse events. A “sit-less” approach is proposed for those unable to maintain regular activity, with glycemic monitoring for those with variability. Conclusions PA is crucial in T2DM management. Conflicting findings regarding glycemic control warrant further investigation to ascertain causes, whether related to bias or other factors.
Źródło:
European Journal of Translational and Clinical Medicine; 2024, 7, 1; 97-105
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Correlation between atherogenic risk and adiponectin in gestational diabetes mellitus
Autorzy:
Matyjaszek-Matuszek, B.
Lenart-Lipinska, M.
Kowalczyk-Boltuc, J.
Szlichtyng, W.
Paszkowski, T.
Powiązania:
https://bibliotekanauki.pl/articles/51752.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2014, 21, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Glycosaminoglycans of human serum and their alterations in diabetes mellitus
Autorzy:
Koźma, Ewa
Olczyk, Krystyna
Głowacki, Andrzej
Komosińska, Katarzyna
Sonecki, Piotr
Najmiec, Tomasz
Jaźwiec, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1045134.pdf
Data publikacji:
1996
Wydawca:
Polskie Towarzystwo Biochemiczne
Źródło:
Acta Biochimica Polonica; 1996, 43, 3; 567-574
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Poziom lęku u osób chorych na cukrzycę
Anxiety in diabetes mellitus
Autorzy:
Kocemba, Iwona
Powiązania:
https://bibliotekanauki.pl/articles/2139146.pdf
Data publikacji:
2004
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
diabetes mellitus type 2
women
adult
anxiety
STAI
HbA1c
Opis:
Diabetes in an incurable disease. The diabetes treatment consists of keeping the blood glucose at a low level. The first aim of this study was to estimate the relationship between anxiety of healthy women and women with type 2 diabetes The second aim was to estimate the relationship between anxiety and metabolic control in diabetic women. The first group which was examined consisted of 66 women with type 2 diabetes who were at hospital and second group was formed of 66 healthy women. The average age of both groups was 53. I used the State Trait anxiety Inventory (STAI) by C. D. Spilbergera and glycosylated hemoglobin for glycemic control. The research indicates that the diabetic women had a significantly higher level of trait anxiety and poorer metabolic control was correlated with state anxiety.
Źródło:
Acta Universitatis Lodziensis. Folia Psychologica; 2004, 08; 103-112
2353-4842
Pojawia się w:
Acta Universitatis Lodziensis. Folia Psychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Macrophages in Diabetes Mellitus: A Review on Understanding of Macrophage Function
Autorzy:
Chatterjee, Susraba
Guria, Srikanta
Powiązania:
https://bibliotekanauki.pl/articles/1059398.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Alloxan
Beta-cell Therapy
Cytokines
Diabetes mellitus
Diabetic Nephropathy
Diabetic Retinopathy
Macrophage
Macrophage Type 1
Macrophage Type 2
Streptozotocin
Opis:
Diabetes mellitus (DM) causes millions of deaths all over the world. Immune system contains macrophages that play very important role in DM. Excessive secretion of different cytokines can induce the DM development. Diabetes mellitus (DM) also affect the function of macrophage. We review the important findings regarding the role of macrophage in DM. This review may emphasize future direction towards development of novel immune-modulatory therapeutic intervention.
Źródło:
World Scientific News; 2019, 134, 2; 319-325
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Age-dependent systemic DNA damage in early Type 2 Diabetes mellitus
Autorzy:
Rogulj, Dinko
El Aklouk, Ismail
Konjevoda, Paško
Ljubić, Spomenka
Pibernik Okanović, Mirjana
Barbir, Ante
Luburić, Marijana
Radman, Maja
Budinski, Ninoslav
Vučić Lovrenčić, Marijana
Powiązania:
https://bibliotekanauki.pl/articles/1038637.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
metabolic syndrome
type 2 diabetes mellitus
DNA damage
urinary 8-OHdG
Opis:
Oxidative stress, capable of eliciting damage to various biomolecules including DNA, is a recognized component of diabetes mellitus and its complications. Metabolic syndrome (MetS) is associated with the development of type 2 diabetes mellitus (T2DM), as well as other unfavorable outcomes. The aim of this study was to elucidate the role of oxidative stress in the development of T2DM, by investigating association of oxidative DNA damage with metabolic parameters in subjects with MetS and early T2DM. Selected anthropometric and biochemical parameters of MetS, inflammation and oxidative DNA damage: body mass index (BMI), fatty liver index (FLI), waist circumference (WC), total cholesterol, HDL and LDL-cholesterol, gamma-glutamyl transpeptidase (GGT), uric acid, C-reactive protein (CRP), total leukocyte/neutrophil count, and urinary 8-hidroxy-deoxyguanosine (u-8-OHdG) were assessed in male subjects with MetS and both younger (≤55 years) and older (>55 years) subjects with T2DM of short duration without complications. BMI, FLI, WC, total and LDL-cholesterol and uric acid were higher, while the u-8-OHdG was lower in MetS group, when compared to older T2DM subjects. None of these parameters were different neither between MetS and younger T2DM, nor between two sub-groups of subjects with T2DM. Values of CRP, HDL-cholesterol, triglycerides, GGT, leukocytes and neutrophils were not different between all examined groups of subjects. Higher 8-OHdG in older subjects with T2DM suggests that both aging process and diabetes could contribute to the development of DNA damage. Oxidative DNA damage cannot serve as an universal early marker of T2DM.
Źródło:
Acta Biochimica Polonica; 2017, 64, 2; 233-238
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Osobowość młodzieży chorej na cukrzycę
The personality of adolescents with diabetes mellitus
Autorzy:
Szymańska, Sylwia
Powiązania:
https://bibliotekanauki.pl/articles/2139249.pdf
Data publikacji:
2000
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
diabetes mellitus type 1
adolescents
personality traits
Opis:
The aim of this study was evaluation of personality traits’ differences between adolescents with diabetes (type 1) and their healthy peers. 100 diabetics (age 16–22,17) and 103 healthy adolescents were assessed. They completed Cattell’s the 16 Personality Questionnaire. The diabetics are significantly different from their healthy peers in a factor H (resistance-lack of resistance) and factors of the second degree – introversion–extraversion and worry–integration. Girls with diabetes are different from healthy girls in a factor C (emotionally stability–neurosis). The diabetics are less resistant to stress, have bigger difficulty in making social contacts, are more shy and anxiously. The girls with diabetes are more neurotic than the healthy girls.
Źródło:
Acta Universitatis Lodziensis. Folia Psychologica; 2000, 04; 57-65
2353-4842
Pojawia się w:
Acta Universitatis Lodziensis. Folia Psychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Paraoxonase-1 activities in children and adolescents with type 1 diabetes mellitus
Autorzy:
Craciun, Elena
Leucuta, Daniel
Rusu, Razvan
David, Bianca
Cret, Victoria
Dronca, Eleonora
Powiązania:
https://bibliotekanauki.pl/articles/1038772.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
paraoxonase-1
lactonase
arylesterase
children
type 1 diabetes mellitus
Opis:
Background: Paraoxonase-1 is an HDL-associated esterase that acts as an anti-atherogenic agent by protecting LDL from oxidation. This study investigates paraoxonase-1 activities in children and adolescents with type 1 diabetes mellitus and possible associations with other biochemical markers. Patients and methods: The study enrolled 82 children and adolescents with type 1 diabetes mellitus and 41 controls with similar age and gender distribution. Serum paraoxonase-1 arylesterase and salt-stimulated paraoxonase activities were assessed by measuring the rates of phenyl acetate and paraoxon hydrolysis, respectively; paraoxonase-1 lactonase activity and oxidized LDL were assessed by a pH-sensitive colorimetric assay and ELISA, respectively. Glycated haemoglobin HbA1c and lipid profile were assayed with an immunoturbidimetric method and commercially available kits, respectively. Results: We found lower paraoxonase-1 activities in diabetics when compared to controls. The decrease was statistically significant only for the lactonase activity, the difference being higher when referring to the subgroup with poor glycaemic control. The lactonase activity/HDL ratio was also lower in diabetics vs. controls, but without statistical significance. Both lactonase and arylesterase activities were negatively correlated with HbA1c in diabetics, but only the latter was statistically significant (ρ = -0.21, P = 0.055; ρ = -0.24, P = 0.03, respectively). A correlation coefficient of ρ = 0.196 (P = 0.078) was found between oxidized LDL and HbA1c. Conclusion: All paraoxonase-1 activities were lower in diabetic children and adolescents, but only the decrease in the lactonase activity was statistically significant. Although lipid profile and glycaemic control were altered in diabetics, no differences were observed between groups regarding oxidized LDL level.
Źródło:
Acta Biochimica Polonica; 2016, 63, 3; 511-515
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selenium and copper in type 2 diabetes mellitus - more doubt than certainty
Autorzy:
Zabłocka-Słowińska, K.
Grajeta, H.
Powiązania:
https://bibliotekanauki.pl/articles/960069.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Opis:
Type 2 diabetes mellitus (T2DM) is one of the most common chronic illnesses nearly all over the world and the prevalence of this disorder is still growing. Particularly in industrialized countries, it has become the most serious global medical and public problem, next to cancer and cardiovascular diseases. Despite intensive developments in the research on T2DM pathogenesis, the impact of nutritional factors, and particularly the effect of trace elements, on the development of this disease has not been identified completely, although relationships between some elements, e.g. Zn, Fe, Cr, and T2DM have been described in detail. Critical review of the literature indicates that the majority of inconsistencies appear in studies on Cu and Se: on the one hand, these minerals have strong antioxidant properties and even insulin-mimetic action; on the other hand, an increased risk of T2DM positively correlates with a high dietary intake of Se and Cu or supplementation with these elements. High content of these minerals in diets observed in selected countries and/or increasing popularity of dietary supplementation with Se or Cu, especially among chronically ill patients including ones with T2DM, can cause distortions in the molecular pathways of glucose metabolism. The influence of these minerals on inducing diabetic complications is even more vague and depends on several factors, e.g. the body status of these and other trace elements, the type of complications and the duration of T2DM. The relationship between T2DM and the status of Se and Cu is complex and bidirectional, thus a well-balanced diet providing these trace elements in proper amounts, according to the demand of an organism, may be one of the strategies in reducing the risk of T2DM and its complications.
Źródło:
Journal of Elementology; 2017, 22, 1
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Type III Polyglandular Autoimmune Syndromes in children with type 1 diabetes mellitus
Autorzy:
Ben-Skowronek, I.
Michalczyk, A.
Piekarski, R.
Wysocka-Lukasik, B.
Banecka, B.
Powiązania:
https://bibliotekanauki.pl/articles/49668.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction: Type III Polyglandular Autoimmune Syndrome (PAS III) is composed of autoimmune thyroid diseases associated with endocrinopathy other than adrenal insufficiency. This syndrome is associated with organ-specific and organ-nonspecific or systemic autoimmune diseases. The frequency of PAS syndromes in diabetic children is unknown. Objectives: The aim of the study was to evaluate the incidence of PAS III in children with diabetes mellitus type 1. Patients and methods: The study consisted of 461 patients with diabetes mellitus type 1(T1DM), who were 1-19 years of age. TSH, free thyroxin, TPO autoantibodies, and thyroglobulin autoantibodies were determined annually. Autoimmune Hashimoto’s thyroiditis was diagnosed in children with positive tests for TPO Ab and Tg Ab and thyroid parenchymal hypogenicity in the ultrasound investigation. Elevated TSI antibodies were used to diagnose Graves’ disease. Additionally, Anti-Endomysial Antibodies IgA class were determined every year as screening for celiac disease. During clinical control, other autoimmune diseases were diagnosed. Adrenal function was examined by the diurnal rhythm of cortisol. Results: PAS III was diagnosed in 14.5% children: PAS IIIA (T1DM and autoimmune thyroiditis) was recognized in 11.1 % and PAS III C (T1DM and other autoimmune disorders: celiac disease, and JIA, psoriasis and vitiligo) in 3.5% children. PAS IIIA was more prevalent in girls than in boys – 78.4% versus 21.6% (p<0.05). PAS III was observed between 1-5 years of life in 66.6% children; the frequency decreased in consecutive years and successively increased in the adolescence period to 22.7%. Conclusions: PAS III occurs in 14.5% of children with DM type1 and the incidence is positively correlated with patients’ age and female gender. Children with PAS III should be carefully monitored as a group at risk for the development of other autoimmune diseases.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Activity of superoxide dismutase obtained from senile cataract lens - effect of diabetes mellitus
Autorzy:
Panz, Tomasz
Wójcik, Rafał
Krukar-Baster, Krystyna
Powiązania:
https://bibliotekanauki.pl/articles/1040692.pdf
Data publikacji:
2008
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Cu,Zn superoxide dismutase activity
senile cataract
diabetes mellitus
Opis:
The activity of Cu,Zn superoxide dismutase in the fluid obtained from eye lens capsules after cataract surgery was investigated in samples obtained from patients with senile cataract and with senile cataract combined with diabetes mellitus. Two parameters were measured and compared: the frequency of occurrence of detected superoxide dismutase activity and the relative activity of the enzyme in samples derived from senile cataract patients versus those from the patiens affected additionally by diabetes mellitus. It was confirmed that the decrease of superoxide dismutase activity during cataract was additionally promoted by diabetes mellitus.
Źródło:
Acta Biochimica Polonica; 2008, 55, 4; 821-823
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Knowledge on risk factors for type 2 diabetes mellitus among secondary school students
Autorzy:
Gora, A.
Szczepanska, E.
Janion, K.
Powiązania:
https://bibliotekanauki.pl/articles/2087307.pdf
Data publikacji:
2020
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
knowledge
high school students
type 2 diabetes mellitus
risk factors
Opis:
Background. Diabetes is a set of metabolic diseases characterized by hyperglycemia caused by improper action and/ or secretion of insulin. Currently, diabetes is becoming a serious challenge in modern medicine, this disease affects 425 million people, and the forecasts indicate that by 2045 the number of cases will increase to 629 million. Objective. The aim of the study was to evaluate the knowledge about risk factors for type 2 diabetes among secondary school students in the Silesian Province in Poland and to determine whether there are differences between the level of knowledge between girls and boys and between first-, second- and third-grade students. Material and methods. The survey was conducted among 650 high school students. The research tool was the author's questionnaire. The obtained results were developed using Microsoft Excel 2010 and Statistica 13.3 (TIBCO Inc.). Results. The definitions of type 2 diabetes were known to 63.9%. 91.8% of high school students indicated excessive body mass as a risk factor for morbidity, while 18.8% of people indicated the appropriate type of obesity increasing the risk of type 2 diabetes. Most of the students considered abnormal eating habits as an important factor increasing the occurrence of the disease (92.4%). The most numerous group of high school students were people with average level of knowledge (89.6%). Conclusions. The knowledge of high school students about risk factors for type 2 diabetes was varied. The most numerous group were high school students characterised by the average level of knowledge. There were no statistically significant differences between the proportion of correctly provided responses by women and men. There were statistically significant differences between the proportion of correctly provided responses by first-, second- and third-graders. Our research shows that educational activities should be undertaken, especially about modifiable risk factors for type 2 diabetes.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2020, 71, 4; 431-443
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Complications in the early adaptation period of neonates of mothers with gestational diabetes mellitus
Autorzy:
Setlak, Marcin
Radosz, Patrycja
Radwan, Aneta
Okoń, Aneta
Klinicka, Paulina
Górny, Agata
Powiązania:
https://bibliotekanauki.pl/articles/1179541.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
early adaptation period
gestational diabetes mellitus
hyperbilirubinaemia
hypertrophy
hypotrophy
Opis:
Diabetes is one of the common complications during pregnancy. Insulin-dependent diabetes, lasting from childhood, is an outcome of 0,5% of pregnancies, while significantly more pregnant women is diagnosed with gestational diabetes. It is believed to be a risk factor of more frequent occurence of neonatal complications. The aim of our research was to present the most common complications in the early adaptation period of diabetic mothers’ neonates. Retrospective research included 222 neonates of mothers with GDM that were hospitalized in the Neonatal Unit in Katowice from 2009 to 2017. In the study group 199 newborns were born by caesarean section and 23 by natural labour. 23 (10,36%) neonates had features of hypertrophy, whereas 30 (13,51%) – hypotrophy. 33 children (14,86%) have been diagnosed with carbohydrate disorders. Complications in the early adaptation period occurred in 44,1% of neonates and hyperbilirubinaemia was the most frequent (55,1%). Among the developmental anomalies, the most common was the congenital heart disease - 10.81% of newborns. Complications in the early adaptation period occur often in diabetic mothers' neonates, in particular: carbohydrate disorders, pathological jaundice and PIVH features in additional examinations. 10,81% of neonates have been diagnosed with non-critical heart disease.
Źródło:
World Scientific News; 2017, 76; 183-189
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Stigma and its relationship with life satisfaction in patients with type 2 diabetes mellitus
Autorzy:
Turen, Sevda
Yurtsever, Melike
Powiązania:
https://bibliotekanauki.pl/articles/40418503.pdf
Data publikacji:
2024-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
life satisfaction
stigma
type 2 diabetes mellitus
Opis:
Introduction and aim. This study aims to determine the level of stigma in patients with type 2 diabetes mellitus (T2DM) and evaluate its relationship with their life satisfaction. Material and methods. This is a descriptive and cross-sectional study conducted in a single tertiary care center. Two hundred and ten patients ≥18 years old diagnosed with T2DM were included in this study. The relationship between the “Type 2 diabetes stigma assessment scale” and the “Satisfaction with life scale” was assessed using Pearson correlation analysis. Results. The average age of the participants was 54.85±15.81 years. The majority of patients reported adherence to diabetes treatment and having comorbidities. Stigma levels were higher in patients ≤65 years, those with less than a high school education, and those receiving insulin or oral anti-diabetic treatment, but lower with a T2DM diagnosis duration of ≤ 5 years (p<0.05). Life satisfaction was influenced by age, education status, economic status, adherence to treatment, dietary compliance, and the presence of comorbidities. A moderately negative relationship between stigma level and life satisfaction was identified. Conclusion. The study’s results indicate that an increase in stigma level is associated with a decrease in life satisfaction in patients with type 2 diabetes mellitus.
Źródło:
European Journal of Clinical and Experimental Medicine; 2024, 22, 1; 128-133
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prevalence of diabetes mellitus and IFG in the prospective cohort ‘PONS’ study - baseline assessment
Autorzy:
Zatonska, K.
Ilow, R.
Regulska-Ilow, B.
Szuba, A.
Rozanska, D.
Wolyniec, M.
Einhorn, J.
Vatten, L.
Asvold, B.O.
Manczuk, M.
Zatonski, W.A.
Powiązania:
https://bibliotekanauki.pl/articles/49335.pdf
Data publikacji:
2011
Wydawca:
Instytut Medycyny Wsi
Tematy:
prevalence
diabetes mellitus
impaired fasting glucose
PONS project
Polska
Polish population
Źródło:
Annals of Agricultural and Environmental Medicine; 2011, 18, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Female mouse model of diabetes mellitus induced by streptozotocin and high-carbohydrate high-fat diet
Autorzy:
Guo, R.
Dong, J.
Wang, D.Q.
Gu, Y.F.
Powiązania:
https://bibliotekanauki.pl/articles/16627528.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
diabetes mellitus
female mouse
pathological analysis
streptozotocin
high-carbohydrate high-fat diet
Opis:
With the improvement of people’s living standards and rapid economic development, the incidence of diabetes mellitus (DM) is increasing in most parts of the world. DM presents an important potential threat to human health. In the present study, a model of diabetes in female mice was established, and fasting blood glucose was detected at week 4, after which the biochemical profiles were evaluated by histopathological analysis. The success rate of modeling in the normal control (NC) group and the low/ middle/high-dose streptozotocin (STZ) group were 0, 0, 25% and 60%, respectively. In the middle-dose and high-dose STZ groups, the liver index was increased significantly compared with the NC group (p<0.05). The blood biochemical indicators of total cholesterol and low density lipoprotein cholesterol in three STZ injection groups were as follows: alanine aminotransferase and aspartate transaminase in middle- and high-dose STZ groups, high-density lipoprotein cholesterol and serum creatinine in the high-dose STZ group, and blood urea nitrogen in the middle-dose STZ group were significantly increased (p<0.05). The level of total triglycerides was lower, obviously, in the high-dose STZ group than in the NC group (p<0.05). The mice showed marked steatosis, green-dyed fiber tissue coloring in varying degrees, and the contour of the hepatic lobules basically disappeared in STZ injection groups. The results suggest that to establish a diabetes model for female ICR mice, the optimum dose of STZ is 100 mg/kg.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 4; 547-555
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Protein-bound glycosaminoglycans in serum of patients with lung cancer and patients with diabetes mellitus
Autorzy:
Olczyk, Krystyna
Kucharz, Eugeniusz
Głowacki, Andrzej
Sonecki, Piotr
Kościelniak-Kocurek, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1045604.pdf
Data publikacji:
1992
Wydawca:
Polskie Towarzystwo Biochemiczne
Źródło:
Acta Biochimica Polonica; 1992, 39, 1; 101-105
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
PREVELANCE OF METFORMIN-INDUCED GASTROINTESTINAL PROBLEMS
Autorzy:
Sadeeqa, Saleha
Fatima, Madeeha
Latif, Sumera
Afzal, Hafsa
Nazir, Saeed Ur Rashid
Saeed, Hamid
Powiązania:
https://bibliotekanauki.pl/articles/895256.pdf
Data publikacji:
2019-12-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Diabetes Mellitus
metformin
Gastrointestnal
Opis:
Metformin is used as an anti-diabetic drug among oral hypoglycemic drugs, which produces many gastrointestinal problems. Study aims to investigate the effect of metformin induced gastrointestinal problems and its prevalence. A cross-sectional study design was adapted using convenience sampling technique, at different Diabetic Centers of Lahore and Faisalabad, Pakistan from, June-2017 to November-2017. A total of 300 male and female patients participated in the study between 26 to 85 years and diagnosed with type-II diabetes. Data was directly collected from the patients and prevalence of metformin-induced gastrointestinal intolerance was determined by the symptoms of the patients. Data was analyzed by SPSS version 21. Results showed a significant difference between gender and symptoms (p=0.029). Moreover, the gastrointestinal problems were found to be dose related. A significant difference existed between patients who were taking 500mg and those taking 850 mg of metformin (p=0.006), patients who were taking 500mg and those taking 1000mg of metformin (p=0.000) and patients who were taking 850mg with those taking 1000mg of metformin (p=0.022). The prevelance of metformin-induced gastrointestinal symptoms was 45.8%. Most commonly occurring symptoms were, constipation (41.35%) followed by dyspepsia (27.89%), abdominal pain (26.92%), bloating and heart burn (25%), indigestion (15.38%), anorexia (11.54%), diarrhea (6.58%), flatulence (7.69%), nausea (6.73%) and vomiting (2.88%). It was concluded that gastrointestinal intolerance was more in females as compared to males. The gastrointestinal problems increased with the increase in dose. The side effects occurred were irrespective of the age and the most common gastrointestinal symptom was found to be constipation.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 6; 1073-1077
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prevalence of depression in Indian patients with type 2 diabetes mellitus and/or hypertension: DEPTH Study
Autorzy:
Lalwani, Raj Kumar
Shah, Jayesh Dashrathlal
Chatterjea, Tapas
Nadakuduru, Papa Rao
Erande, Suhas
Powiązania:
https://bibliotekanauki.pl/articles/454720.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
comorbidity
diabetes
depression
hypertension prevalence
type 2 diabetes mellitus
Opis:
ABSTRACT Introduction. Depression, a common psychiatric mood disorder, is a leading cause of disability and a significant contributor to the overall global burden of disease. Aim. To determine the prevalence of depression in patients with controlled and uncontrolled type-2 diabetes mellitus (T2DM) and/or hypertension (HTN) in India. The association of depression with socio-demographic profile and clinical risk factors was also assessed. Material and methods. In this cross-sectional epidemiological study, T2DM and/or HTN patients attending outpatient department at tertiary care hospitals and private clinics across 54 cities in India were enrolled. The primary outcome measure was to determine the prevalence of depression in T2DM, HTN and T2DM + HTN patients. Association of depression with patients’ demography, socio-economic status, anxiety, and clinically diagnosed insomnia were also investigated. Results. Of 1829 patients, the prevalence of depression in T2DM, HTN and T2DM+HTN cases were found to be 51.03%, 46.94% and 48.64%, respectively. A higher proportion of patients with uncontrolled T2DM and HTN reported depression (T2DM: 77.64% vs. 22.36%; HTN: 72.49% vs. 27.51%). There was a significant association between anxiety and severity of depression across all indications (p<0.0001). Depression was significantly associated with complications in T2DM (p=0.0001) and comorbidities in T2DM + HTN (p=0.0023) cases. Conclusion. Depression is highly prevalent and has a direct significant association with various socio-demographic variables and anxiety in Indian patients with T2DM and/or HTN.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 4; 315-325
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zmiany w błonach komórkowych erytrocytów ludzi chorych na cukrzycę
Changes in human erythrocyte membrann diabetes mellitus
Autorzy:
Szosland, Konrad
Bryszewska, Maria
Powiązania:
https://bibliotekanauki.pl/articles/944962.pdf
Data publikacji:
1992
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Źródło:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica; 1992, 9
0208-614X
Pojawia się w:
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analyses of hospitalization of diabetes mellitus patients in Poland by gender, age and place of residence
Autorzy:
Gajewska, M.
Gebska-Kuczerowska, A.
Gorynski, P.
Wysocki, M.J.
Powiązania:
https://bibliotekanauki.pl/articles/49617.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Aim. The purpose of this study was to analyze the hospitalization of diabetes mellitus patients in Polish hospitals in 2005-2009. Materials and Methods. Data was taken from a nationwide database, kept at the National Institute of Public Health – National Institute of Hygiene in Warsaw. Data gathered for this work related to patients whose main cause of hospitalization was diabetes. Results. In the period of five years the number of diabetes-caused hospitalizations increased by nearly 22% – from 172.2 per 100 thousand in 2005 to 209.9 per 100 thousand in 2009. Hospital treatment covered mainly patients suffering from type 2 diabetes (116.4 per 100 thousand in 2009), as well as type 1 diabetes (87.6 per 100 thousand in 2009). Patients under 39 years of age were more often hospitalized because of type 1 diabetes, whereas in the older age groups patients were more often treated in hospitals for type 2 diabetes. Generally, in both types of the disease, older patients required hospitalizations more often than the younger ones. Cardiovascular diseases were the most reported co-morbidity in both types of the disease. In 2005-2009 the hospital mortality rate decreased with regard to both types of diabetes and an average length of hospital stay decreased by one day, reaching 8.1 days in 2009. Conclusion. It must be emphasized that the growing epidemic of diabetes and its complications are an important challenge to society. The percentage of people hospitalized due to diabetes is increasing every year and consumes significant resources dedicated to health care. Early diagnosis and appropriate treatment of diabetes are imperative, as well as reducing the disparities in access to medical care (ambulatory and stationary) for town and country residences.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy
Zastosowanie ultrasonografii wysokiej rozdzielczości w badaniu nerwu piszczelowego u pacjentów z cukrzycową neuropatią obwodową
Autorzy:
Singh, Kunwarpal
Gupta, Kamlesh
Kaur, Sukhdeep
Powiązania:
https://bibliotekanauki.pl/articles/1033301.pdf
Data publikacji:
2017
Wydawca:
Medical Communications
Tematy:
diabetes mellitus
tibial nerve
ultrasonography
Opis:
Aim of the study: High-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness of nerve fascicles of the tibial nerve with the presence and severity of diabetic peripheral neuropathy. Material and methods: 75 patients with type 2 diabetes mellitus clinically diagnosed with diabetic peripheral neuropathy were analysed, and the severity of neuropathy was determined using the Toronto Clinical Neuropathy Score. 58 diabetic patients with no clinical suspicion of diabetic peripheral neuropathy and 75 healthy non-diabetic subjects were taken as controls. The cross sectional area and maximum thickness of nerve fascicles of the tibial nerves were calculated 3 cm cranial to the medial malleolus in both lower limbs. Results: The mean cross sectional area (22.63 +/– 2.66 mm2 ) and maximum thickness of nerve fascicles (0.70 mm) of the tibial nerves in patients with diabetic peripheral neuropathy compared with both control groups was significantly larger, and statistically significant correlation was found with the Toronto Clinical Neuropathy Score (p < 0.001). The diabetic patients with no signs of peripheral neuropathy had a larger mean cross sectional area (14.40 +/– 1.72 mm2 ) and maximum thickness of nerve fascicles of the tibial nerve (0.40 mm) than healthy non-diabetic subjects (12.42 +/– 1.01 mm2 and 0.30 mm respectively). Conclusion: The cross sectional area and maximum thickness of nerve fascicles of the tibial nerve is larger in diabetic patients with or without peripheral neuropathy than in healthy control subjects, and ultrasonography can be used as a good screening tool in these patients.
Cel pracy: Ultrasonografia wysokiej rozdzielczości nerwu piszczelowego jest szybką i nieinwazyjną metodą możliwą do wykorzystania w rozpoznaniu cukrzycowej neuropatii obwodowej. Celem naszej pracy było ustalenie, czy istnieje zależność pomiędzy polem przekroju poprzecznego oraz maksymalną grubością pęczków nerwu piszczelowego a występowaniem i zaawansowaniem cukrzycowej neuropatii obwodowej. Materiał i metoda: Badaniu poddano 75 pacjentów cierpiących na cukrzycę typu 2 z klinicznym rozpoznaniem cukrzycowej neuropatii obwodowej. Stopień zaawansowania neuropatii oceniany był za pomocą Klinicznej skali neuropatii Toronto (Toronto Clinical Neuropathy Score). Grupę kontrolną w badaniu stanowiło 58 pacjentów z cukrzycą bez objawów klinicznych cukrzycowej neuropatii obwodowej oraz 75 zdrowych osób. Pole przekroju poprzecznego oraz maksymalna grubość pęczków nerwu piszczelowego wyliczane były na wysokości 3 cm powyżej kostki przyśrodkowej w obu kończynach dolnych. Wyniki: Średnie pole przekroju poprzecznego (2,63 +/− 2,66 mm2) oraz maksymalna grubość pęczków nerwu piszczelowego (0,70 mm) u pacjentów z cukrzycową neuropatią obwodową były istotnie statystycznie większe niż u osób z obu grup kontrolnych. Stwierdzono także występowanie istotnej statystycznie zależności pomiędzy wielkością tych parametrów a stopniem zaawansowania cukrzycowej neuropatii obwodowej według Klinicznej skali neuropatii Toronto (p < 0,001). U pacjentów chorujących na cukrzycę bez występowania objawów klinicznych cukrzycowej neuropatii obwodowej pole przekroju poprzecznego (14,40 +/− 1,72 mm2) oraz maksymalna grubość pęczków nerwu piszczelowego (0,40 mm) były większe niż u zdrowych uczestników badania (odpowiednio 12,42 +/− 1,01 mm2 i 0,30 mm). Wnioski: Przekrój oraz maksymalna grubość pęczków nerwu piszczelowego są większe niż u osób zdrowych zarówno u pacjentów z cukrzycą cierpiących na cukrzycową neuropatię obwodową, jak i bez klinicznych objawów neuropatii. Ultrasonografia może być z powodzeniem wykorzystywana u chorych z cukrzycą jako badanie przesiewowe pod kątem występowania cukrzycowej neuropatii obwodowej. Artykuł w wersji polskojęzycznej jest dostępny na stronie http://jultrason.pl/index.php/wydawnictwa/volume-17-no-71
Źródło:
Journal of Ultrasonography; 2017, 17, 71; 246-252
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diabetes association of polyps and colon cancer
Autorzy:
Miłek, Tomasz
Forysiński, Karol
Myrcha, Piotr
Ciostek, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1392134.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
colorectal cancer
colorectal polyps
diabetes mellitus
Opis:
Aim: The aim of the study was to retrospectively assess the relationship between the occurrence of polyps and colon cancer in patients with type 2 diabetes. Methods: In 2014–2015, 976 colonoscopies were performed in patients. We compared the number of polyps with high-grade dysplasia and colorectal cancers in patients with and without diabetes. In addition, in the diabetic group we documented the relationship between HbA1C and the occurrence of polyps with high-grade dysplasia, and colon cancer. The data were statistically analyzed. Results: 1. Patients with diabetes show a higher incidence of polyps with high-grade dysplasia/carcinoma – 32/91 (35.16%) in comparison to patients without diabetes – 136/885 (15.37%), P < 0.001; 2. Patients with diabetes show a higher incience of polyps with cancer – 9/91 (9.89%) as compared to patients without diabetes – 18/885 (2.03%), P < 0.001. 3) Colorectal cancer occurred significantly more often in uncontrolled diabetes (P = 0.022). Conclusion: The conducted study shows a significant association between type 2 diabetes and the incidence of colorectal adenomas. These findings may lead to a conclusion that diabetic patients are at a higher risk of developing colorectal cancer, thus are in higher need for controlled colonoscopy. Therefore, it may be worth considering a scheme for screening patients in the above-mentioned group with colonoscopy.
Źródło:
Polish Journal of Surgery; 2019, 91, 4; 9-12
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Coexistence of type 1 diabetes mellitus and spinal muscular atrophy in an 8-year-old girl: a case report
Autorzy:
Borkowska, Anna
Jankowska, Agnieszka
Szlagatys-Sidorkiewicz, Agnieszka
Sztangierska, Beata
Liberek, Anna
Plata-Nazar, Katarzyna
Kamińska, Barbara
Powiązania:
https://bibliotekanauki.pl/articles/1039156.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Spinal muscular atrophy
diabetes mellitus
children
Opis:
The spinal muscular atrophy is a rare autosomal recessive genetic disease characterized by the progressive loss of muscular strength. In its natural course the disease leads to death. Diabetes mellitus type 1 is an autoimmune metabolic disorder characterized by the disturbed insulin synthesis. This is a case report of an 8-year-old girl suffering from Werdnig Hoffman disease in whom DM1 was diagnosed. The unspecific clinical manifestation and diagnostic difficulties are presented in this paper. To the authors' knowledge, this is the first publication concerning the co-existence of these two medical conditions.
Źródło:
Acta Biochimica Polonica; 2015, 62, 1; 167-168
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Factors associated with poor glycaemic control in type 2 diabetic elderly patients with mild cognitive impairment
Autorzy:
Gorska-Ciebiada, M.
Ciebiada, M.
Powiązania:
https://bibliotekanauki.pl/articles/2098566.pdf
Data publikacji:
2021
Wydawca:
Instytut Medycyny Wsi
Tematy:
diabetes mellitus
elderly
mild cognitive impairment
Opis:
Introduction and objective. Recently, data has indicated a higher incidence of mild cognitive impairment (MCI) in patients with diabetes. Old age is a risk factor for cognitive deterioration and dementia. The aim of the study was to find the factors associated with poor glycaemic control in type 2 diabetic elderly patients with MCI. Materials and method. A cross-sectional study was conducted on 87 diabetic patients with MCI in an outpatient clinic. All subjects were screened for MCI using the Montreal Cognitive Assessment (MoCA). Detailed medical history and collection of blood test samples were performed. Results. 83.9% of participants had poor glycaemic control. A positive correlation was found between HbA1c level and number of visit to a doctor per year, number of co-morbidities, duration of T2DM, triglycerides and fasting glucose level; and a negative correlation between HbA1c level and years of education, HDL cholesterol level and MoCA score. The univariate logistic regression models revealed factors which are associated with poor glycemic control are: less years of education, higher no of visit to doctor per year, increased number of co-morbidities, presence of CVD, retinopathy, higher levels of triglycerides and fasting glucose, lower level of HDL cholesterol, lower MoCA score. Multivariable model revealed that higher plasma levels of fasting glucose and triglycerides are significant predictors. Conclusions. There is a high prevalence of poor glycemic control patients among elderly diabetics with MCI. Higher plasma levels of fasting glucose and triglycerides seems to be the most important predictors of poor glycemic control, however father larger studies are needed to elucidate these relationships.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2019, 13, 4; 143-149
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High-density lipoprotein (HDL) cholesterol - more complicated than we think?
Autorzy:
Nessler, K.
Windak, A.
Grzybczak, R.
Nessler, M.B.
Siniarski, A.
Gajos, G.
Powiązania:
https://bibliotekanauki.pl/articles/2081847.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
cardiovascular disease
diabetes mellitus
dysfunctional HDL
Opis:
Introduction and objective. There are some clinical situations where a high level of HDL cholesterol (HDL-C) may be unfavourable. In these situations, HDL-C may undergo some changes, and even if its quantity is within the reference range, its quality is no longer the same. Brief description of state of knowledge. Diabetes is the state of elevated oxidative stress. Studies conducted to-date have revealed an increased production of the reactive forms of oxygen as the result of tissue damage in diabetes patients. The expression ‘dysfunctional HDL’ has been coined in the literature to describe high-density lipoproteins that lose their antioxidative and anti-inflammatory properties, that is, HDL-C that loses its basic functions. Recent observational studies have confirmed that the atheroprotective activity of properly functioning HDL-C is frequently impaired in clinical situations associated with oxidative stress. The presented review lays the foundation for a new approach to understanding how the functional properties of HDL help reduce cardiovascular risk. Conclusions. In the light of presented findings it seems that there is a need to seek a better diagnostic marker than HDL-C level. This study presents some possible directions for future research to bring us closer to the full understanding of the HDL particle and its role in patients with ischemic heart disease and type 2 diabetes.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 3; 517-526
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Stężenie glukozy w surowicy krwi w podostrym zatruciu chlorpyrifosem – insektycydem fosforoorganicznym
Serum glucose concentration in subacute intoxication with chlorpyrifos – Organophosphate insecticide
Autorzy:
Łukaszewicz-Hussain, Anna
Powiązania:
https://bibliotekanauki.pl/articles/2166328.pdf
Data publikacji:
2014-11-04
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
chlorpyrifos
glukoza
cukrzyca
glucose
diabetes mellitus
Opis:
Wstęp: Z badań epidemiologicznych wynika, że narażenie na pestycydy fosforoorganiczne zwiększa ryzyko zachorowania na niektóre choroby, m.in. neurologiczne (np. chorobę Parkinsona, chorobę Alzheimera) i układu krążenia, a także na cukrzycę. Celem niniejszej pracy była ocena stężenia glukozy w surowicy krwi szczurów przy podostrym zatruciu niskimi dawkami chlorpyrifosu - związku fosforoorganicznego stosowanego jako insektycyd. Materiały i metody: Badania wykonano na szczurach samcach szczepu Wistar, którym przez 14 lub 28 dni sondą dożołądkowo podawano raz dziennie roztwór olejowy chlorpyrifosu w dawce 0,2; 2 lub 5 mg/kg m.c./dzień. Zwierzęta z grupy kontrolnej otrzymywały olej. W surowicy oznaczano stężenie glukozy metodą kolorymetryczną przy użyciu gotowych zestawów. Wyniki: Stwierdzono wzrost stężenia glukozy w surowicy po 14 dniach podawania chlorpyrifosu w najwyższej badanej dawce oraz po 28 dniach podawania związku we wszystkich badanych dawkach. Wnioski: Zarówno uzyskane wyniki (wzrost stężenia glukozy w surowicy krwi w podostrym zatruciu chlorpyrifosem), jak i dane z piśmiennictwa sugerują, że narażenie na insektycydy fosforoorganiczne może sprzyjać rozwojowi cukrzycy. U osób mających zawodowy kontakt z tymi związkami konieczne jest więc częstsze wykonywanie badań diagnostycznych w kierunku jej wczesnego wykrycia. Med. Pr. 2013;64(4):527–531
Background: Epidemiological studies suggest that exposure to organophosphate insecticides enhances the risk of various diseases, including neurological disorders, e.g. Parkinson's or Alzheimer's disease, arteriosclerosis and diabetes mellitus. For this reason the aim of the presented study was to estimate serum concentration of glucose in subchronic intoxication with low doses of chlorpyrifos, an organophosphate insecticide. Materials and Methods: The rats received chlorpyrifos at a daily dose of 0.2, 2 or 5 mg/kg b.w./day for 14 or 28 days. For biochemical determinations of serum glucose in the rats ready-to-use kit was applied. Results: In subacute intoxication with chlorpyrifos the increased serum concentration of glucose was observed after 14 days of intoxication with the highest dose (5 mg/kg b.w.) and after 28 days of intoxication with all dose levels used. Conclusions: The results of this study showing the increased concentration of serum glucose in subacute intoxication with low doses of chlorpyrifos, as well as the literature data suggest that exposure to organophosphate insecticides can increase the risk of diabetes mellitus. It may thus be concluded that people occupationally exposed to these compounds should be subjected to diagnostic tests for early detection of diabetes. Med Pr 2013;64(4):527–531
Źródło:
Medycyna Pracy; 2013, 64, 4; 527-531
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The importance of obesity and carbohydrate metabolism disorders on the course of gastroesophageal reflux disease – a pilot study
Autorzy:
Pardak, Piotr
Filip, Rafał
Krzaczek, Maciej
Powiązania:
https://bibliotekanauki.pl/articles/2203254.pdf
Data publikacji:
2022-05-31
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
obesity
gastroesophageal reflux disease
diabetes mellitus
Opis:
BackgroundCarbohydrate metabolism disorders, obesity and a severe course of gastroesophageal reflux correlate with more frequent development of esophageal complications. The aim of this study was to assess the influence of obesity and carbohydrate disorders on the characteristics of gastroesophageal reflux disease (GERD).Material and methodsThe study included 58 patients with excess weight. Anthropometric parameters (including the body mass index, BMI), data regarding GERD (severity of symptoms, gastroscopy and esophageal pH monitoring results) were included in the study. Correlations between obesity and GERD parameters were analyzed. Subjects were divided into a diabetic and a control group and the severity of GERD was compared.ResultsGERD was diagnosed in 40 patients and occurred more frequently in the obese group (73%) than in the overweight group (57%). Increased GERD severity was associated with increased BMI only for postprandial parameters. GERD was diagnosed in most of the group with carbohydrate disorders (78% vs 63% in the non-diabetic group). No differences in the severity of GERD were observed between groups depending on carbohydrate disorders.ConclusionsIn our study, GERD was common in obesity and in diabetic disorders. Increased severity of postprandial reflux was associated with an increased BMI. Diabetic disorders were not associated with more severe GERD.
Źródło:
European Journal of Translational and Clinical Medicine; 2022, 5, 1; 17-26
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Homocysteine as a non-classical risk factor for atherosclerosis in relation to pharmacotherapy of type 2 diabetes mellitus
Autorzy:
Borowska, Magdalena
Dworacka, Marzena
Winiarska, Hanna
Krzyżagórska, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1038542.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
homocysteine
atherosclerosis
type 2 diabetes
Opis:
Aims. The aim of our study was to evaluate which of the pharmacotherapeutic methods that are frequently used to treat type 2 diabetes is associated with the most beneficial profile in relation to pro-atherogenic homocysteine levels. Patients and Methods. We measured the serum homocysteine level in 182 patients with type 2 diabetes treated with metformin (89), treated with insulin in combination with metformin (31), receiving sulfonylureas (31) and treated conventionally with insulin (31). The total homocysteine levels in the serum were assayed. To exclude the influence of selected metabolic and anthropometric factors on the differences between the examined groups, multivariate analysis of covariance was used (ANCOVA). In this analysis, serum homocysteine concentration was the dependent variable, while diabetes duration, waist circumference, HbA1c, 1,5-anhydro-D-glucitol, fasting glycaemia and peptide C were used as covariates. Results. The serum homocysteine levels in patients treated with insulin in monotherapy were significantly higher than what was observed in the metformin treated subjects and in the patients receiving insulin combined with metformin. The analysis of covariance also confirmed that the differences between the therapeutic groups were affected by waist circumference and the C-peptide levels. Conclusion. We conclude that conventional insulin therapy may have a negative effect on pro-atherogenic homocysteine levels in patients with type 2 diabetes. This study revealed that pro-atherogenic homocysteine levels may not only be modified by pharmacotherapy of type 2 diabetes, but also by beta cell secretory function and abdominal obesity.
Źródło:
Acta Biochimica Polonica; 2017, 64, 4; 603-607
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wsparcie społeczne a kontrola poziomu cukru we krwi w cukrzycy typu 2
Social support and glycemic control in type 2 diabetes mellitus
Autorzy:
Kocemba, Iwona
Powiązania:
https://bibliotekanauki.pl/articles/2139601.pdf
Data publikacji:
2007
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
diabetes mellitus
social support
HbA1c
Opis:
Diabetes is an incurable disease. Recently researchers are focusing more often on the role of the social support in diabetes treatment. It seams that support from family and friends plays a big role in the results of the disease treatment. Lack of such support may decrease patients’ treatment motivations. The aim of this study was to estimate the relationship between social support and metabolic control. The group which was examined consisted of 35 people with type 2 diabetes not treated with insulin and 31 who were on insulin. The Social Support Inventory by Saranson and glycosylated hemoglobin (HbA1c) for glycemic control were used in this study. The research indicates that poorer metabolic control was correlated with the lack of social support.
Źródło:
Acta Universitatis Lodziensis. Folia Psychologica; 2007, 11; 59-65
2353-4842
Pojawia się w:
Acta Universitatis Lodziensis. Folia Psychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparative analysis of socioeconomic, behavioral and biological factors between healthy patients and patients with newly diagnosed diabetes in the Lubuskie Voivodeship
Autorzy:
Bonikowska, I.
Jasik-Pyzdrowska, J.
Szwamel, K.
Powiązania:
https://bibliotekanauki.pl/articles/2087637.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
patients
type 2 diabetes mellitus
prediabetic state
Opis:
Background: The most effective way to prevent an increasing diabetic population lies in early detection of risk factors and diagnosis of carbohydrate metabolism disorders. Aim of the study: The study aimed at determining socio-economic variables, lifestyle behaviours and biological factors differentiating patients with newly diagnosed diabetes from diabetes-free individuals. Material and methods: Assessment of diabetic vs. non-diabetic individuals was performed according to the American criteria issued by the Commission on Social Determinants of Health as well as the FINDRISC form, which helps identify patients who are at risk of developing type 2 diabetes on the basis of multi-factorial determinants of its development. The research was conducted in 2018 among 1167 primary health care patients from Lubuskie Voivodeship using a diagnostic survey method which interviewed the respondents according to the FINDRISC standard questionnaire. Results: The group of healthy patients was similar to the group of patients with newly diagnosed diabetes with respect to variables such as age (p=0.713), sex (p=1), place of residence (p=1), level of education (p=0.076), professional activity (p=0.758), BMI (p=0.133), waist measurement (p=0.665), frequency of fruit and vegetables intake (p=0.572), frequency of taking hypotensive medications (p=0.176), frequency of diabetes occurrence in the family history (p=0.227) and physical activity (p=0.321). Conclusions: Early detection of carbohydrate metabolism disorders, with the use of standardised tools that assess diabetes development, appears to be essential in the prevention of this disorder. Therefore, there is a strong need to create a tool adjusted to socio-demographic factors such as geographical location, economic conditions and lifestyle. Additionally, active and massive screening for carbohydrate metabolism disorders in patients with a low risk of diabetes seems to be crucial in its prevention.
Źródło:
Medical Science Pulse; 2020, 14, 3; 55-63
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The analysis of health behaviors and illness acceptance in patients with diabetes
Autorzy:
Starczewska, Małgorzata
Kujawska, Renata
Stanisławska, Marzanna
Rybicka, Anita
Grochans, Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/551609.pdf
Data publikacji:
2018
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
diabetes mellitus
health
Acceptance of Illness Scale
Źródło:
Family Medicine & Primary Care Review; 2018, 4; 352-355
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Endocrine disorders in patients with hereditary hemochromatosis
Autorzy:
Banaszkiewicz, Katarzyna
Sikorska, Katarzyna
Sworczak, Krzysztof
Powiązania:
https://bibliotekanauki.pl/articles/895739.pdf
Data publikacji:
2019-02-05
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
Diabetes Mellitus
Osteoporosis
endocrinology
iron overload
hemochromatosis
Opis:
Hereditary hemochromatosis (HH) is a rare genetic disorder, developing secondary to the accumulation of iron in tissues, which may lead to multiple organ failure. If untreated, it may result in liver cirrhosis or cardiomyopathy. The damage to the pancreas and the anterior pituitary, on the other hand, leads to a decreased production and secretion of hormones that are essential to life. Common symptoms of HH, that are distressing for patients, include joint pain, particularly involving hands and wrists, as well as the chronic fatigue syndrome. Iron overload affects the skeletal system, leading to osteoporosis. The pathological accumulation of iron in the anterior pituitary impairs the gonadotropin synthesis, resulting in reduced serum levels of testosterone in men and estrogens in women. This, however, contributes to lower bone mass. In vivo tests have also revealed that abnormal iron accumulation is related to an increased activity and number of osteoclasts, as well as the influence on the differentiation and activity of osteoblast-lineage cells. Based on a systematic review of literature, hereditary hemochromatosis (HH) will be presented as a chronic disease, affecting most of the endocrine glands.
Źródło:
European Journal of Translational and Clinical Medicine; 2018, 1, 2; 72-76
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Osobowość pacjentek z cukrzycą typu 2
The personality of diabetic women
Autorzy:
Kocemba, Iwona
Powiązania:
https://bibliotekanauki.pl/articles/2139340.pdf
Data publikacji:
2003
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
diabetes mellitus type 2
women
adult
personality
Opis:
The aim of this study was to estimate the relationship between personality of 66 healthy women and 66 women with type 2 diabetes. The average age of both groups was 63. I use the 16th Personality Factors Test by Cattell. A lower level of intelligence characterizes the personality of a diabetic, they are more submissive, effusive and responsible. They are calmer and more practical in their behavior. Healthy women are more self-sufficient and unconventional.
Źródło:
Acta Universitatis Lodziensis. Folia Psychologica; 2003, 07; 77-85
2353-4842
Pojawia się w:
Acta Universitatis Lodziensis. Folia Psychologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The seven-year epidemiological study of legal abortion caused by heart disease, blood disorders, diabetes and hypertension as referred to forensic medicine centers in Fars Province
Autorzy:
Ghodrati, Fatemeh
Saadatmand, Narjes
Gholamzadeh, Saeid
Akbarzadeh, Marzieh
Powiązania:
https://bibliotekanauki.pl/articles/552001.pdf
Data publikacji:
2019
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
heart diseases
diabetes mellitus
hypertension
abortion
legal.
Opis:
common risk factors for high risk pregnancies and spontaneous or therapeutic abortions. Objectives. To investigate the legal abortion caused by heart disease, blood disorders, diabetes and hypertension as referred to forensic medicine centers in Fars Province from 2007 to 2013. Material and methods. In a retrospective, cross-sectional study, samples consisted of all documents of people referred to forensic medicine centers in Shiraz since 2007 to 2013, comprising of 1664 files. Data collection tools included a demographic forum and the checklist of abortion causes. SPSS.16.0 was applied to analyze the data through descriptive statistical analysis. Results. The most frequent age group was 25–29 years at 31.5% (n = 522) and the lowest was over 40 years old at 4.15% (n = 70). The statistical report of the reasons for legal abortion permission were 19% (n = 63), 24.4% (n = 81), 10.54% (n = 35), and 8.13% (n = 27) due to heart problems, blood disorders, hypertension, and diabetes mellitus, respectively. Most frequent legal abortion permits by forensic medicine due to maternal causes were between the years of 2011–2012 at 17.8–28% (n = 59–93). The relationship between legal abortion permission at The Forensic Medicine Center at different years and maternal ages was statistically significant (p < 0.00001). Conclusions. The most common prevalent reason of abortion was Blood Disorder – 81 patients (24.4%) and heart disease – 63 cases (19%). It is essential that family education and prevention of repeated pregnancies be done with high-risk women. Also, initiation of pregnancy care at lower gestational age in identifying risky pregnancies and timely control of complications must also be undertaken
Źródło:
Family Medicine & Primary Care Review; 2019, 1; 23-29
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The psychological and emotional state of patients with type 2 diabetes mellitus on the background of excessive body weight
Autorzy:
Velichko, V. I.
Nikitina, V. I.
Said, E. V.
Amirova, A. Yu.
Powiązania:
https://bibliotekanauki.pl/articles/765447.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Mikołaja Kopernika w Toruniu. Wydział Nauk o Ziemi i Gospodarki Przestrzennej. Katedra Kultury Fizycznej
Tematy:
diabetes mellitus type 2, overweight, depressive disorders, anxiety disorders, psychoemotional status
Opis:
In the work, we studied the parameters of the psychological and emotional state of patients with type 2 diabetes mellitus on the background of excessive body weight. Psychological and emotional state studies were conducted using the Patient Health Questionnaire-PHQ-9, questionnaire the hospital scale of anxiety and depression (HADS). A comparison of the frequency of occurrence of anxiety-depressive disorders and the study of the degree of their severity in the patients under study. The study revealed that negative changes in the indicators of psychological and emotional state in patients with type 2 diabetes are six times more likely than in healthy people.
Źródło:
Journal of Education, Health and Sport; 2017, 7, 3
2391-8306
Pojawia się w:
Journal of Education, Health and Sport
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Amatorskie nurkowanie pacjentów z rozpoznaną cukrzycą
Diabetic patients who are amateur divers
Autorzy:
Ługowska, D.
Ługowski, T.
Krzywińska, O.
Kozakiewicz, M.
Grzelakowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/1359563.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Medycyny i Techniki Hiperbarycznej
Tematy:
cukrzyca
nurkowanie amatorskie
diabetes mellitus
recreational diving
Opis:
Cukrzyca to „epidemia XXI wieku”, szacuje się, że w 2011 roku na cukrzycę chorowało 6,7% populacji Polski, z czego jedna czwarta nie miała świadomości choroby. Tak duże rozpowszechnienie cukrzycy sprawia, że coraz więcej lekarzy staje przed problemem prawidłowej kwalifikacji pacjenta z cukrzycą do amatorskiego uprawiania sportu, w tym nurkowania. W niniejszej publikacji przedstawiono najważniejsze informacje dotyczące oceny ryzyka, dopuszczenia do amatorskiego nurkowania pacjentów z cukrzycą oraz proponowanych protokołów postępowania przed i podczas uprawiania tego sportu.
Diabetes is an "epidemic of the 21st century" and it is estimated that in 2011 6.7% of Poland's population suffered from diabetes, one quarter of which was unaware of the disease. Such a high prevalence of diabetes mellitus results in an increasing number of physicians being confronted with the problem of qualifying patient with diabetes to partake in amateur sports, including diving. This publication presents the most important information concerning risk assessment, admission of diabetic patients to amateur diving and some proposed protocols of management before and during sport practice.
Źródło:
Polish Hyperbaric Research; 2018, 3(64); 39-44
1734-7009
2084-0535
Pojawia się w:
Polish Hyperbaric Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Death due to rare rhinocerebral mucormycosis infection: a case report
Autorzy:
Baral, T.
Mugada, V.
Kolakota, R.K.
Powiązania:
https://bibliotekanauki.pl/articles/2088062.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
Mucormycosis
Diabetes mellitus
Orbital cellulitis
amphotericin B
Opis:
Background: Rhinocerebral mucormycosis is the most common form of mucormycosis in patients with diabetes mellitus; it is linked to poor prognosis, presenting most commonly in an acute setting, mimicking symptoms of sinusitis or periorbital cellulitis. The general survival rate in chronic cases is 83%, compared to 10–35% in acute. Aim of the study: To report a death due to rhinocerebral mucormycosis in a 45-year-old male patient. Case report: In this case report a 45-year-old male presented with acute rhinocerebral mucormycosis and was admitted in a state of unconsciousness with complaints of sudden onset weakness of right upper and lower limb, motor aphasia, right facial swelling, orbital swelling, and diminished distant vision. Upon primary diagnosis of stroke, treatment started immediately. However, past medical history from patient’s attendants revealed that the patient underwent a tooth extraction procedure 20 days prior, and had since developed redness of the right eye, diminished distant vision, and swelling of the right side of the face. Pus was drained, and reports revealed orbital cellulitis with an intracranial spread. By the time of admission to hospital, the patient had abnormal lab profiles (WBC, ESR, serum creatinine), acute kidney injury, with MRI revealing rhinocerebral mucormycosis. The patient developed septic shock and died during treatment. Conclusions: Acute mucormycosis carries a high mortality rate. Pleiotropic manifestations and organ dysfunction add to the further risk of mortality. Timely diagnosis and management may increase the chances of the survival rate of the patient.
Źródło:
Medical Science Pulse; 2019, 13, 4; 40-43
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association between UBE2E2 variant rs7612463 and type 2 diabetes mellitus in a Chinese Han Population
Autorzy:
Kazakova, Elena
Wu, Yanhui
Zhou, Zhongyu
Chen, Meijun
Wang, Tongtong
Tong, Huixin
Zhuang, Tianwei
Sun, Lulu
Qiao, Hong
Powiązania:
https://bibliotekanauki.pl/articles/1039098.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Type 2 diabetes mellitus
UBE2E2
rs7612463
Single nucleotide polymorphism
SNPscan
Opis:
UBE2E2 encodes ubiquitin-conjugating enzyme E2E2, which plays an important role in the synthesis and secretion of insulin. Two previous studies indicated that SNPs in UBE2E2 were associated with risk for type 2 diabetes mellitus (T2DM) in the Japanese and Korean populations, respectively. We examined the association of one SNP in this gene, rs7612463, with the risk of T2DM in 1957 Han participants in northeastern China, using an SNPscanTM Kit. rs7612463 genotype was significantly associated with risk for T2DM under various genetic models, including an additive model (P = 0.004), a dominant model (P = 0.024), and a recessive model (P = 0.008). The AA genotype was associated with a significantly decreased risk for T2DM (P = 0.004, OR = 0.513, 95% CI = 0.325-0.810) after adjustment for age, gender, and BMI. The heterozygous genotype, AC, was associated with increased risk for total cholesterol (mmol l-1; P = 0.031) and triglycerides (mmol l-1; P = 0.039) in control individuals. Our results show that rs7612463 is associated with T2DM, with homozygotes of the AA genotype at decreased risk for T2DM in the Chinese population. Additionally, heterozygotes may have decreased risk of T2DM due to insulin resistance.
Źródło:
Acta Biochimica Polonica; 2015, 62, 2; 241-245
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Endophthalmitis following cataract surgery in diabetic patients
Autorzy:
Maya-Sapira, Hanapi
Koh, Yi-Ni
Azhany, Yaakub
Zunaina, Embong
Khairy-Shame, Sonny-Teo
Liza-Sharmini, Ahm ad Tajuddin
Draman, Nani
Noordin, Zamri
Powiązania:
https://bibliotekanauki.pl/articles/552628.pdf
Data publikacji:
2017
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
endophthalmitis
cataract surgery
diabetes mellitus
Streptococcus mitis.
Źródło:
Family Medicine & Primary Care Review; 2017, 4; 431-436
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Infuence of HbA1c, serum lipids, blood pressure and BMI on Auditory Brainstem Response in diabetic patients
Autorzy:
Dąbrowski, Mariusz
Mielnik-Niedzielska, Grażyna
Nowakowski, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/454729.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
auditory brainstem response diabetes mellitus
serum lipids
Opis:
Introduction. Impaired hearing organ function including abnormalities in auditory brainstem response (ABR) are more frequent in diabetic subjects compared to the general population. The aim of our study was to assess the impact of selected modifiable factors on ABR latencies in diabetic subjects. Material and Methods. 58 patients with type 1 and type 2 diabetes, aged <45 years, with diabetes duration <10 years, and without clinically overt hearing impairment or diabetic neuropathy, were included. In all subjects vital signs and blood samples were obtained, and ABR audiometry was performed. Results. Significantly delayed latencies in ABR were found in patients with total cholesterol <192 mg/dL, with HDL-cholesterol <49.5 mg/dL, with triglycerides >89 mg/dL, with presence of hypertension, and with systolic and diastolic blood pressure >135 and >78 mm Hg respectively. A linear correlation between triglycerides and wave I and III latencies, and between systolic blood pressure and wave III latency were revealed. A relationship between ABR latencies and HbA1c, LDL-cholesterol or BMI was not found. Conclusions. Several modifiable factors affect functioning of the retrocochlear part of the auditory pathway. If these results were confirmed in further studies, a vast area of possible therapeutic interventions to preserve hearing function in diabetic patients would become available.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 3; 185-191
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of neutrophil phagocytic, complement functions, and cytokines expression among diabetic patients in Abuja, Nigeria
Autorzy:
Babandina, Musa Muhammad
Mainasara, Abdullahi Suleiman
Bakare, Mustapha
Emeribe, Anthony Uchenna
Shuwa, Halima Ali
Haruna, Shamsuddeen
Muhammad, Aminu Said
Abdullahi, Idris Nasir
Powiązania:
https://bibliotekanauki.pl/articles/454973.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
diabetes mellitus
effector molecules
pro-inflammatory markers
Opis:
Introduction. Inflammatory response in Diabetes Mellitus (DM) begins with chronic sub-clinical inflammations as a result of insulin resistance and activation of both innate and adaptive immune system as the disease progresses to complicated diabetes. Hence, the present study investigated the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among diabetic and non-diabetic patients attending the National Hospital in Abuja, Nigeria. Aim. To evaluate the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among post-operative septic diabetic and post-operative septic non-diabetic patients at the National Hospital in Abuja, Nigeria. Material and methods. Subjects were recruited by convenient sampling technique through interviewer-administered questionnaires. Subsequently, blood samples were collected. Fasting blood sugar (FBS) (mmol/L) was determined using glucose oxidase method. Neutrophil function test (Fmol/phag) was assayed using nitroblue tetrazolium reduction test (NBT). Hemolytic complement function (CH 50) test was conducted using serum harvested from sheep sensitized with human group (ORh D +ve) red blood cells. While serum Interleukin-4, -6, -10 and TNF- α were determined using Enzyme Linked Immunosorbent Assay (ELISA). Results. Mean ± Standard deviation (SD) of FBS concentration of 10.5 ± 1.3 (mmol/|L) among diabetic and 4.7 ± 0.9 (mmol/L) among non-diabetics was recorded. There is a decrease in neutrophil phagocytic function with a mean ± SD of 5.4 ± 2.1 (Fmol/ phag) in diabetics compared to 9.2 ± 2.1 (Fmol/phag) in non-diabetics. Similarly, complement (CH 50) function and C-reactive protein were significantly lower in diabetics when compared to non-diabetics (p<0.001). There was a significant difference in IL-6 concentration between diabetics and non-diabetics groups, but no significant difference was observed in TNF-α, IL-4 and IL-10 concentrations between study groups (p>0.05). TNF-α and IL-6 was significantly higher in diabetics with cardiovascular disorders compared to non-diabetics subjects with cardiovascular disorders (p<0.001). Conclusion. Findings from this study revealed the association of complement, neutrophil phagocytic function, CRP and IL-6 among septic diabetic patients,. In addition TNF-α and IL-6 expression was higher in DM patients with cardiovascular disorders.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 3; 229-235
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the Finnish Diabetes Risk Score (FINDRISC) for diabetes screening in occupational health care
Autorzy:
Vandersmissen, Godelieve J.
Godderis, Lode
Powiązania:
https://bibliotekanauki.pl/articles/2177344.pdf
Data publikacji:
2015-04-24
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
diabetes mellitus
occupational health
questionnaires
cross-sectional studies
Opis:
Objectives The objective of the study was to investigate the prevalence of undiagnosed dysglycaemia and the risk for type 2 diabetes using the Finnish Diabetes Risk Score (FINDRISC) in the working population of Belgium. Moreover, it was to evaluate performance and applicability of FINDRISC as a screening tool during occupational health surveillance. Material and Methods A cross-sectional analysis was carried out over the years 2010–2011 among 275 healthy employees who underwent a health check including fasting plasma glucose and the FINDRISC questionnaire. The sensitivity, specificity and predictive value of different FINDRISC cut-off values to detect dysglycaemia was revised in the literature and then calculated. Results The prevalence of unknown dysglycaemia was 1.8%. Twelve percent of the employees had a FINDRISC score of 12 to 14 corresponding to a moderate risk of 17% to develop diabetes within the next 10 years, and 5.5% had a score of 15 or more corresponding to a high – very high risk of 33% to 50%. All dysglycaemic individuals had a FINDRISC score of 12 or higher. The sensitivity and specificity for detecting dysglycaemia was respectively 100% and 84.1% for a FINDRISC cut-off value ≥ 12; and 80% and 95.9% for a cut-off value ≥ 15. Conclusions A considerable number of workers had dysglycaemia or was at risk for developing type 2 diabetes. The questionnaire is a reliable, valuable and easy to use screening tool in occupational health surveillance.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2015, 28, 3; 587-591
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of acetylsalicylic acid and circulating microRNAs in primary prevention of cardiovascular events in patients with Diabetes Mellitus Type 2 - a review
Autorzy:
Chabior, A.
Pordzik, J.
Mirowska-Guzel, D.
Postuła, M.
Powiązania:
https://bibliotekanauki.pl/articles/2085138.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
diabetes mellitus
primary prevention
platelets
acetylsalicylic acid
microRNA
Opis:
Introduction. Type 2 diabetes mellitus (T2DM) is a common metabolic disorder, which carries a risk for atherosclerosis and cardiovascular impairment. The purpose of this review is to demonstrate the role of acetylsalicylic acid (ASA) in primary cardiovascular prevention in T2DM patients, as well as present an outline of microRNAs (miRNA) relevant to ASA therapy and should be evaluated as targets to improve treatment. Brief description of state of knowledge. Although the etiology of hypercoagulable state in T2DM is considered multifactorial, attention mainly focuses on platelet disturbances. Platelets in T2DM not only demonstrate intensified adhesion, activation, aggregation, and thrombin generation, but are likely to deliver miRNAs at specific sites of action in the cardiovascular system, hence contributing to the pathogenesis of cardiovascular events. Objective. Since cardiovascular disease (CVD) is currently the leading cause of mortality among T2DM patients, appropriate risk stratification and management is necessary to reduce morbidity and mortality in this group. A large number of T2DM patients show inadequate response to antiplatelet therapy, which currently revolves around ASA, despite compliance with treatment regimens proposed by the guidelines. Conclusions. The review shows that the use of ASA for primary prevention is beneficial in patients at high cardiovascular risk. However, it is important to select patients in whom ASA therapy will bring the most beneficial outcome with minimal risk for adverse effects. This can be potentially achieved with the use of unique biomarkers. The biologically diverse characteristics of miRNA make them a promising novel biomarker and potential tool for better risk stratification, as well as antiplatelet therapy optimization.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 515-522
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Eating habits of patients with type 2 diabetes mellitus with regard to body mass index
Nawyki żywieniowe pacjentów z cukrzycą typu 2 z uwzględnieniem wskaźnika masy ciała
Autorzy:
Janion, Karolina
Szczepańska, Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/765988.pdf
Data publikacji:
2017
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
BMI
diabetes mellitus
eating habits
cukrzyca
nawyki żywieniowe
Opis:
INTRODUCTION: Recent years have seen a significant increase in the incidence of diabetes mellitus, type 2 diabetes in particular, which closely correlates with the growing problem of overweight and obesity. The aim of the study was to compare eating habits among type 2 diabetic patients with varying body weight as well as to verify whether there was a relationship between dietary habits and the body mass index in these patients. MATERIAL AND METHODS: The study was conducted in diabetology outpatient clinics. A total of 353 diabetic patients participated in the study. The study consisted of two parts, i.e. authors' questionnaire and anthropometric measurements. RESULTS: The recommended number of 4–5 meals a day was declared by 48.6% of subjects with normal body weight, 50.3% of overweight and 48.4% of obese patients. Daily consumption of breakfast was confirmed by 77.1%, 73.9% and 77.8% of respondents, respectively. Daily consumption of whole-grain bread and coarse grits was mostly declared by subjects with normal body weight (62.8%), followed by overweight and obese patients (22.9% and 23%, respectively). Daily consumption of milk and fermented dairy beverages was reported by 24.3% and 15.7% of subjects with normal body weight, 22.3% and 14.7% of overweight patients as well as by 16.7% and 12% of obese patients, respectively. CONCLUSIONS: Eating habits among patients with type 2 diabetes are varied, with healthy eating habits dominating in subjects with normal body weight. A relationship was found between the patients’ BMI values and some of the eating habits as well as consumption rates of various food products.
WSTĘP: W ostatnich latach odnotowuje się znaczący wzrost zachorowalności na cukrzycę, zwłaszcza typu 2, co ściśle koreluje z narastającym problemem nadwagi i otyłości. Celem pracy było porównanie nawyków żywieniowych pacjentów z cukrzycą typu 2 o różnej masie ciała oraz odpowiedź na pytanie, czy występują zależności pomiędzy nawykami a wskaźnikiem masy ciała (BMI) badanych osób. MATERIAŁ I METODY: Badanie zostało przeprowadzone w poradniach diabetologicznych wśród 353 pacjentów z cukrzycą. Składało się z dwóch części – przeprowadzenia ankiety z wykorzystaniem autorskiego kwestionariusza oraz wykonania pomiarów antropometrycznych. WYNIKI: Spożywanie zalecanej liczby 4–5 posiłków w ciągu dnia zadeklarowało 48,6% osób z prawidłową masą ciała, 50,3% z nadwagą oraz 48,4% z otyłością. Codzienne spożywanie I śniadania potwierdziło odpowiednio 77,1%, 73,9% oraz 77,8% z nich. Codzienną konsumpcję pełnoziarnistego pieczywa i gruboziarnistych kasz najczęściej deklarowały osoby z prawidłową masą ciała (62,8%), rzadziej osoby z nadwagą i otyłością, odpowiednio 22,9% i 23% wskazań. Spożycie mleka i mlecznych napojów fermentowanych każdego dnia deklarowało odpowiednio 24,3% i 15,7% osób z prawidłową masą ciała, 22,3% i 14,7% z nadwagą oraz 16,7% i 12% z otyłością. WNIOSKI: Nawyki żywieniowe badanych pacjentów z cukrzycą typu 2 są zróżnicowane, przy czym największą liczbę prawidłowych nawyków żywieniowych zaobserwowano u osób z prawidłową masą ciała. Stwierdzono, iż występuje zależność pomiędzy BMI badanych pacjentów a niektórymi nawykami żywieniowymi i częstością spożycia poszczególnych produktów spożywczych.
Źródło:
Annales Academiae Medicae Silesiensis; 2017, 71; 363-370
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Factors Associated with Physical Activity in People with Diabetes
Autorzy:
Sieńko-Awieraniów, Elżbieta
Stępień-Słodkowska, Marta
Latkowska, Agnieszka
Głowacka, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1054668.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
Body Mass Index
diabetes mellitus
lifestyle
physical activity
Opis:
Background: Diabetes mellitus is a chronic disease related to the occurrence of numerous metabolic disorders. Their common feature is hyperglycaemia, caused by insufficient insulin secretion or its malfunction. The World Health Organization states that 346 million people worldwide have diabetes. The studies in adults with type 2 diabetes clearly demonstrate that the change of lifestyle behaviours effectively improves glycemic control. The modifications of lifestyle habits, such as regular physical activity and healthier dietary habits prove to be beneficial for patients. The aim of this study was to determine the factors affecting the level of physical activity in people with diabetes mellitus. Methods: Research material consisted of the data gathered from a diagnostic survey, which was conducted in a form of a questionnaire. The study included 60 people with type 1 or type 2 diabetes. Results: Unfortunately, the results show that not all of them were active enough, which is so crucial for stabilizing the disease. Conclusions: The diagnosis of diabetes in the respondents resulted in more time being spent by them on physical activity, which resulted in the improvement of diabetes control and the normalization of body weight according to BMI, thus increasing the effectiveness of diabetes treatment and reducing complications. The frequency of the physical activity undertaken by the respondents prior to the disease was not related to gender, however, after the diagnosis, it was dependent on gender
Źródło:
Central European Journal of Sport Sciences and Medicine; 2015, 12, 4; 73-81
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-50 z 132

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