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    Wyświetlanie 1-5 z 5
    Tytuł:
    Natural and Synthetic Coumarins and their Pharmacological Activity
    Autorzy:
    Kubrak, Tomasz
    Podgórski, Rafał
    Sompor, Monika
    Powiązania:
    https://bibliotekanauki.pl/articles/454684.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    coumarins
    antimicrobial agents
    neuroprotection
    natural products in medicine
    Opis:
    Coumarins are a structurally diverse group of natural substances derives from plants that display a host of bioactivities. In this paper, we will introduce the reader to coumarins and their applications as medicinal substances. The great diversity in courmarin structure will be discussed along with their extensive use as pharmaceutical agents. Coumarins display a wide range of antimicrobial activity and applications of coumarins as antifungal and antiviral agents will be addressed. Other properties of coumarins such as their role in neuroprotection, anticancer, and as antioxidants will also be reviewed.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2017, 2; 169-175
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Flavonoids and coumarins from Hieracium pilosella L. [Asteraceae]
    Autorzy:
    Gawronska-Grzywacz, M
    Krzaczek, T.
    Powiązania:
    https://bibliotekanauki.pl/articles/59337.pdf
    Data publikacji:
    2009
    Wydawca:
    Polskie Towarzystwo Botaniczne
    Tematy:
    weed
    flavonoids
    invasive weed
    mouse-ear hawkweed
    coumarin
    herb
    Compositae
    Hieracium pilosella
    Opis:
    Typical chromatographic methods were successfully applied to isolate nine flavonoid compounds and two coumarin glycosides from the inflorescences and the herb of Hieracium pilosella L. Repeated column chromatography, occasionally paper chromatography and recrystallization made the separation of three flavonoid aglycones and six glycosides - possible. Coumarin glycosides were isolated by preparative thin layer chromatography. Subsequent UV, NMR and MS analyses have led to identification of the following flavonoid derivatives: known for the species - apigenin, luteolin, luteolin 7-O- ß-glucopyranoside, luteolin 4’-O-ß-glucopyranoside, isoetin 7-O-ß- -glucopyranoside, isoetin 4’-O-ß-glucuronide and new for the species – kaempferol 3-methyl ether and apigenin 7-O-ß-glucopyranoside. Third isoetin glycoside contained two different sugar moieties: xylose and glucose, probably attached to the hydroxyl groups at C-4’ or C-4’ and C-2’(or 5’) of an aglycone. Umbelliferone 7-O-ß-glucopyranoside (skimmin) and new for the genus Hieracium esculetin 7-O-ß-glucopyranoside (cichoriin) were determined by NMR and MS methods.
    Źródło:
    Acta Societatis Botanicorum Poloniae; 2009, 78, 3; 189-195
    0001-6977
    2083-9480
    Pojawia się w:
    Acta Societatis Botanicorum Poloniae
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Variability of composition of essential oil and coumarin compounds of Angelica archangelica L.
    Autorzy:
    Forycka, A.
    Buchwald, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/2048982.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    Angelica archangelica
    essential oil
    coumarins
    furanocoumarins
    chemical composition
    chemotaxonomy
    olejek eteryczny
    kumaryny
    furanokumaryny
    chemotaksonomia
    skład chemiczny
    Opis:
    The medicinal and culinary properties of Angelica archangelica L. have been known and valued since the Middle Ages. Ingredients of essential oil and coumarins found in this plant are to a large degree responsible for its pharmacological activity. This study is a review of the literature of the most important biologically active compounds present in herbal raw materials: root (rhizome with roots) and angelica fruits. Research shows that the content of individual compounds of the essential oil and coumarin fraction is variable, which may point to a large intraspecific variation. Therefore, these compounds may be good markers for identifying taxa or chemotypes in chemotaxonomic research valuable for the herbal medicine and pharmaceutical industry.
    Źródło:
    Herba Polonica; 2019, 65, 4; 62-75
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Developmental and chemical characteristics of Melittis melissophyllum L. in limited access of sunlight
    Autorzy:
    Szymborska-Sandhu, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049054.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    shading
    developmental stage
    seed viability
    flavonoids
    phenolic acids
    coumarins
    zacienienie
    fazy rozwojowe
    żywotność nasion
    flawonoidy
    kwasy fenolowe
    kumaryny
    Opis:
    Introduction: Bastard balm grows in forests, in central and southeastern part of Europe. The herb of this species is rich in phenolics, mainly flavonoids, phenolic acids and coumarins. The plant is used in traditional European medicine, in digestive problems and for aromatizing tobacco and alcohol products. Objective: The purpose of this study was to determine the influence of shading on bastard balm development and the accumulation of phenolics in its herb, with special respect to coumarin as a quality marker of this raw material. Methods: The plants were cultivated in full sunlight, in 30% and 50% shade provided by shading nets. The herb was harvested from plants in the third year of vegetation, at four subsequent developmental stages and then subjected to chemical evaluation. In the raw material, the total contents of flavonoids, phenolic acids and coumarins was determined. The content of coumarin was analyzed using HPLC-DAD. Results: Plants grown in 30% shade produced the highest number of flowers and seeds. They produced the highest mass of herb at the beginning of the seed-setting stage. The plants grown in full sunlight revealed the highest content of flavonoids and phenolic acids, especially during flowering and at the beginning of the seed-setting stage. The mass of herb obtained by plants cultivated at deep (50%) shade was the lowest, however, the content of coumarin in these plants was the highest. Conclusion: The influence of shade on bastard balm was expressed by the herb mass and coumarin content increment. The plants thrived best in 30% shade, both in terms of flowering abundance and the mass of herb, whereas those from 50% shade were the richest in coumarin.
    Źródło:
    Herba Polonica; 2020, 66, 1; 1-8
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Gene-to-metabolite network for coumarins biosynthesis in natural accessions of Arabidopsis thaliana
    Autorzy:
    Siwinska, J.
    Olry, A.
    Hehn, A.
    Bourgaud, F.
    Lojkowska, E.
    Ihnatowicz, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/80417.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    conference
    coumarin
    secondary metabolite
    biosynthesis
    antimicrobial activity
    antioxidative activity
    biotic stress
    abiotic stress
    Arabidopsis thaliana
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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