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Wyświetlanie 1-15 z 37
Tytuł:
Wpływ średnicy włókien węglowych na odpowiedź komórkową
The effect of the carbon fibres diameter on cell response
Autorzy:
Rajzer, I.
Błażewicz, M.
Menaszek, E.
Czarny, A.
Zaczyńska, E.
Powiązania:
https://bibliotekanauki.pl/articles/284858.pdf
Data publikacji:
2007
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
włóknina węglowa
porowatość
podłoża tkankowe
badania biologiczne
carbon fibres
porosity
tissue engineering scaffolds
biological study
Opis:
W ramach pracy otrzymano włókninę zbudowaną z włókien o różnych średnicach i wielkości, której mikrostruktura posiada biomimetyczny charakter, tzn. składa się z włókien o średnicach zbliżonych do średnic włókien występujących w tkankach. Badania biologiczne wykazały, że włókna o niskich średnicach są gorzej tolerowane przez tkanki.
A three dimensional fibrous material, made from fibres differing in diameters and porosity, has been designed and prepared. These materials will constitute a 3D scaffold containing fibrous components mimicking the structure of natural tissue. The biological studies indicate that the fibres with bigger diameter allow for more intense and quick regeneration of surrounding tissue.
Źródło:
Engineering of Biomaterials; 2007, 10, no. 67-68; 52-56
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The xCELLigence system for real-time and label-free analysis of neuronal and dermal cell response to Equine Herpesvirus type 1 infection
Autorzy:
Golke, A.
Cymerys, J.
Slonska, A.
Dzieciatkowski, T.
Chmielewska, A.
Tucholska, A.
Banbura, M.W.
Powiązania:
https://bibliotekanauki.pl/articles/30665.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
xCELLigence system
real-time analysis
label-free analysis
neuronal cell response
dermal cell response
cell response
equine herpesvirus 1
animal infection
herpesvirus
neuron
neuronal cell
dermal cell
Opis:
Real-time cell electronic sensing (RT-CES) based on impedance measurements is an emerging technology for analyzing the status of cells in vitro. It allows label-free, real time monitoring of the biological status of cells. The present study was designed to assess dynamic data on the cell processes during equine herpesvirus type 1 (EHV-1) infection of ED (equine dermal) cells and primary murine neuronal cell culture. We have demonstrated that the xCELLigence system with dynamic monitoring can be used as a rapid diagnostic tool both to analyze cellular behavior and to investigate the effect of viral infection.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of hydrogen peroxide in regulation of plant metabolism and cellular signalling in response to environmental stresses
Autorzy:
Ślesak, Ireneusz
Libik, Marta
Karpinska, Barbara
Karpinski, Stanislaw
Miszalski, Zbigniew
Powiązania:
https://bibliotekanauki.pl/articles/1041107.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cell wall
cellular redox sensors
transcription factors
photosynthesis
hormone signalling
antioxidants
acclimatory and defence responses
reactive oxygen species (ROS) signalling
cellular metabolism
Opis:
Hydrogen peroxide (H2O2) is produced predominantly in plant cells during photosynthesis and photorespiration, and to a lesser extent, in respiration processes. It is the most stable of the so-called reactive oxygen species (ROS), and therefore plays a crucial role as a signalling molecule in various physiological processes. Intra- and intercellular levels of H2O2 increase during environmental stresses. Hydrogen peroxide interacts with thiol-containing proteins and activates different signalling pathways as well as transcription factors, which in turn regulate gene expression and cell-cycle processes. Genetic systems controlling cellular redox homeostasis and H2O2 signalling are discussed. In addition to photosynthetic and respiratory metabolism, the extracellular matrix (ECM) plays an important role in the generation of H2O2, which regulates plant growth, development, acclimatory and defence responses. During various environmental stresses the highest levels of H2O2 are observed in the leaf veins. Most of our knowledge about H2O2 in plants has been obtained from obligate C3 plants. The potential role of H2O2 in the photosynthetic mode of carbon assimilation, such as C4 metabolism and CAM (Crassulacean acid metabolism) is discussed. We speculate that early in the evolution of oxygenic photosynthesis on Earth, H2O2 could have been involved in the evolution of modern photosystem II.
Źródło:
Acta Biochimica Polonica; 2007, 54, 1; 39-50
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The evaluation of murine pleural lavage fluid cellular composition in experimental hemorrhagic shock with special regard to mast cells morphometry
Autorzy:
Kasacka, I.
Humenczyk-Zybala, M.
Debek, W.
Chyczewski, L.
Niczyporuk, M.
Mycko, G.
Powiązania:
https://bibliotekanauki.pl/articles/70639.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Fizjologiczne
Tematy:
pleural cavity
hemorrhagic shock
brain
inflammatory response
mast cell
neuroendocrine response
morphometry
heart
lung
Źródło:
Journal of Physiology and Pharmacology; 2001, 52, 2
0867-5910
Pojawia się w:
Journal of Physiology and Pharmacology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effect of titanium alloy modified with a-C:N:H and a-SiCxNY(H) coatings on adhesion and immune response of human osteoblast-like MG-63 cells
Autorzy:
Ścisłowska-Czarnecka, A.
Menaszek, E.
Kołaczkowska, E.
Januś, M.
Stypuła, B.
Powiązania:
https://bibliotekanauki.pl/articles/284995.pdf
Data publikacji:
2008
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
titanium alloy
a-C:N:H and a-SiCxNy(H) coatings
osteoblast-like MG-63 cells
cell adhesion
cytokines
Opis:
The study was conducted in order to determine the effects of modified titanium alloy (Ti-6Al-4V) surfaces on the biological response of a human osteoblast-like cell line. MG-63 cells were cultured on disk-shaped Ti-alloys: unmodified, and covered with a-C:N:H or a-SiCxNy(H) layers. Interactions between materials and cells were examined through determination of cells adhesion and secretion of cytokines involved in the development of immune response.
Źródło:
Engineering of Biomaterials; 2008, 11, no. 81-84; 126-128
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selected aspects of endothelial dysfunction and their influence on the atherosclerosis process modeled and analyzed by Petri net based approach
Autorzy:
Formanowicz, D.
Kozak, A.
Formanowicz, P.
Powiązania:
https://bibliotekanauki.pl/articles/80683.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
endothelial dysfunction
biological system
modelling
atherosclerosis
Petri net based model
immunological response
vasodilation
smooth muscle cell
oxidative stress
hypercholesterolemia
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 4
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
ROS production and redox control in response to abiotic stress in seeds and seedlings
Autorzy:
Kranner, I.
Powiązania:
https://bibliotekanauki.pl/articles/80898.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
reactive oxygen species
redox control
abiotic stress
seed germination
seedling development
oxidative modification
protein
oxidative stress
programmed cell death
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Redox state modulation in rice and its implications for plant development and stress responses
Autorzy:
Caverzan, A.
Ribeiro, C.
Lazzarotto, F.
Passaia, G.
Rosa, S.
Garighan, J.
Piovesana, M.
Carvalho, F.
Albenisio, J.
Margis, R.
Margis-Pinheiro, M.
Powiązania:
https://bibliotekanauki.pl/articles/79908.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
reactive oxygen species
scavenging enzyme
detoxification
redox state
rice
plant development
stress response
plant cell
biochemical property
antioxidative enzyme
ascorbate peroxidase
glutathione peroxidase
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rabbit Retinal Ganglion Cell Activation Thresholds in Response to Various Electrical Stimulation Waveforms using a Different Spatial Resolution Electrode Array
Autorzy:
Çelik, M.
Özden, M.
Karagöz, İ.
Sobaci, G.
Powiązania:
https://bibliotekanauki.pl/articles/1032334.pdf
Data publikacji:
2017-06
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
87.85.-d
87.85.D-
87.85.E-
87.85.eg
87.55.dh
87.19.lb
87.85.Ng
Opis:
The analysis of retinal ganglion cell responses to electrical stimulation is invaluable way to understand how the retina reacts and develops. Artificial visual prosthetics have made progress to some extent. Although there are several studies about retinal ganglion cell responses in the literature, experimental findings and information about responses to special stimulation patterns for developing high-resolution visual prosthetics are quite limited. In this study, rabbit retinal tissue was stimulated by biphasic, monophasic and ramp function current pulses with various amplitudes and pulse widths in a set of in vitro experiments. Rabbit retinal ganglion cell responses and spike activities are comparatively analyzed based on the applied electrical stimulation parameters. We conclude that biphasic current pulses provide a lower stimulation threshold of 10 μA with shorter pulse widths than those obtained by monophasic stimulation. Additionally, despite the fact that ramp function stimulation patterns have remarkable potential for eliciting spike formation with low stimulation thresholds, biphasic stimulation is charge-balanced and more convenient for high-resolution visual prosthesis systems.
Źródło:
Acta Physica Polonica A; 2017, 131, 6; 1479-1484
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polyadenylation and decay of 26S rRNA as part of Nicotiana tabacum response to cadmium
Autorzy:
Lewandowska, Małgorzata
Borcz, Barbara
Kamińska, Jolanta
Wawrzyński, Adam
Sirko, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1040862.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
polyadenylation of rRNA
RNA decay
programmed cell death
cadmium
tobacco
Opis:
In contrast to mRNAs, ribosomal RNAs are generally not considered to be polyadenylated. Only a few recent reports describe non-abundant polyadenylated rRNA-related transcripts that have been detected and characterized in yeast and in human cells. Here we depict the phenomenon of 26S rRNA polyadenylation and degradation that was observed in shoots of Nicotiana tabaccum plants grown in the presence of cadmium. Fragments corresponding to 26S rRNA were identified using suppression subtractive hybridization during screening for genes induced in tobacco plants upon a three-week exposure to 15 µM cadmium chloride. Extracts prepared from the above-ground tissues of cadmium-treated tobacco plants were supposed to contain exclusively polyadenylated mRNAs. Surprisingly, numerous polyadenylated fragments matching parts of 26S rRNA were identified and their presence was confirmed by Northern blot and cDNA amplification techniques. To our knowledge this is the first report on rRNA polyadenylation in plants.
Źródło:
Acta Biochimica Polonica; 2007, 54, 4; 747-755
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Osteoblasts response to novel chitosan/agarose/hydroxyapatite bone scaffold – studies on MC3T3-E1 and hFOB 1.19 cellular models
Autorzy:
Kazimierczak, Paulina
Vivcharenko, Vladyslav
Truszkiewicz, Wiesław
Wójcik, Michał
Przekora, Agata
Powiązania:
https://bibliotekanauki.pl/articles/284277.pdf
Data publikacji:
2019
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
bone tissue engineering
biocompatibility
osteoconductivity
cell growth
osteogenic differentiation
Opis:
Since it is known that various cell lines may ex-press different behaviours on the scaffolds surface, a comprehensive analysis using various cellular mo-dels is needed to evaluate the biomedical potential of developed biomaterials under in vitro conditions. Thus, the aim of this work was to fabricate bone scaffolds composed of a chitosan-agarose matrix reinforced with nanohydroxyapatite and compare the biological response of two cell lines, i.e. mouse calvarial preosteoblasts (MC3T3-E1 Subclone 4) and human foetal osteoblasts (hFOB 1.19). Within this study, the osteoblasts number on the scaffold surface and the osteogenic markers level produced by MC3T3-E1 and hFOB 1.19 cells were determined. Furthermore, changes in calcium and phosphorous ions concentrations in the culture media dedicated for MC3T3-E1 and hFOB 1.19 were estimated after the biomaterial incubation. The obtained results proved that the fabricated biomaterial is characterized by biocompatibility and osteoconductivity since it favours osteoblasts attachment and growth. It also supports the production of osteogenic markers (collagen, bALP, osteocalcin) by MC3T3-E1 and hFOB 1.19 cells. Interestingly, the developed biomaterial exhibits different ion reactivity values in the two culture media dedicated for the mentioned cell lines. It was also revealed that mouse and human osteoblasts differ in the cellular response to the fabricated scaffold. Thus, the use of at least two various cellular models is recommended to carry out a reliable biological characterization of the novel biomaterial. These results demonstrate that the tested bone scaffold is a promising biomaterial for bone regeneration applications, however further biological and physicochemical experiments are essential to fully assess its biomedical potential.
Źródło:
Engineering of Biomaterials; 2019, 22, 151; 24-29
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Natural variation in ozone induced cell death in Arabidopsis
Autorzy:
Leppala, J.
Brosche, M.
Powiązania:
https://bibliotekanauki.pl/articles/80797.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
natural variation
atmospheric pollutant
ozone
reactive oxygen species
programmed cell death
molecular response
Arabidopsis thaliana
quantitative trait locus
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Monitoring photosynthetic electron transport during stress responses in Arabidopsis
Autorzy:
Shapiguzov, A.
Cui, F.
Overmyer, K.
Kangasjarvi, J.
Powiązania:
https://bibliotekanauki.pl/articles/80094.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
monitoring
plant cell
chloroplast
reactive oxygen species
signal receptor
immune response
electron transfer chain
plant stress
Arabidopsis
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Modulation of lymphocyte subsets and humoral immune response by florfenicol administered to sheep red blood cell-immunized broiler chickens
Autorzy:
Lis, M.
Szczypka, M.
Suszko-Pawłowska, A.
Świtała, M.
Pawłowski, P.
Obmińska-Mrukowicz, B.
Powiązania:
https://bibliotekanauki.pl/articles/2087412.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
florfenicol
antibodies
bird
broilers
immunity
lymphocytes
Źródło:
Polish Journal of Veterinary Sciences; 2019, 4; 677-683
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Long-term response with everolimus for metastatic renal cell carcinoma refractory to sunitinib-sorafenib sequence
Autorzy:
Kardas, Joanna
Buraczewska, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1065215.pdf
Data publikacji:
2015
Wydawca:
Medical Education
Tematy:
clear cell carcinoma
mTOR inhibitor (mTORi)
metastatic renal cell cancer
overall survival (OS)
progression free survival (PFS)
tyrosine kinase inhibitor (TKI)
Opis:
We presented a 39-year-old male who developed progressive cancer disease 4 years after nephrectomy due to clear cell carcinoma. He was diagnosed with locally reccurence and metastases to the liver, spleen and abdominal muscles. The patient was treated with sunitinib and then after disease progression – with sorafenib. We observed 18 months of cancer control (TKI-TKI). After second progression everolimus was administered. Third line everolimus therapy helped to achieve durable stable disease with PFS 46 months till now (May 2015). The patient remains in very good performance status with minimal toxicity from the regimen. This case illustrates a long term survival for patients with metastatic renal cell carcinoma, a malignancy with historically poor prognosis. The use of three sequential targeted therapies (TKI – TKI – mTORi) helped to achieve over 5 years or disease control, with rarely seen long-term response to third line treatment (mTORi) – where stabilization is good enough. We discussed therapeutic strategies in metastatic renal cell carcinoma according to the literature and therapeutic possibilities in Poland.
Źródło:
OncoReview; 2015, 5, 2; A71-75
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 37

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