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Wyświetlanie 1-25 z 1738
Tytuł:
Stem cells and their outstanding concerns
Komórki macierzyste i ich możliwości zastosowania terapeutycznego
Autorzy:
Lukomska, B.
Powiązania:
https://bibliotekanauki.pl/articles/9895.pdf
Data publikacji:
2012
Wydawca:
Okulistyka Weterynaryjna
Tematy:
stem cell
embryonic stem cell
fetal stem cell
adult stem cell
induced pluripotent stem cell
hematopoietic stem cell
mesenchymal stromal cell
veterinary medicine
Opis:
Stem cells have captured considerable scientific and clinic interest because of their potential to renew themselves and to differentiate into one or more adult cell types. Thus stem cells have been recognized as a potential tool for the development of innovative therapeutic strategies in different disease disorders. Stem cells can be discriminating based on their differentiated potential as totipotent, pluripotent, multipotent or unipotent cells. There are in general three types of stem cells: embryonic, fetal and adult stem cells. While embryonic stem cell therapy has a lot of ethical concerns due to their obtaining but also unlimited proliferation and uncontrolled differentiation, fetal and adult stem cells have been used in the treatment of different diseases. The bone marrow, peripheral blood and umbilical cord blood are ideal sources of adult stem cells because there are easily accessible and contain two types of stem cells: hematopoietic stem cells giving rise to all blood cell types and mesenchymal stem cells differentiating into cells of mesodermal lineage. This review describes the general characteristics of these stem cell populations and their current applications in regenerative medicine. Additionally induced pluripotent stem cells generated through the reprogramming of differentiated adult cells are described.
Możliwość wspomagania regeneracji nieodwracalnie uszkodzonych tkanek i narządów za pomocą transplantacji komórek macierzystych skupia uwagę środowisk medycznych i opinii publicznej. Komórki macierzyste mają zdolność do samo-odnowy oraz do różnicowania się w dojrzałe komórki struktur całego organizmu. Na określonych etapach rozwoju osobniczego wykazują różny stopień ograniczenia potencjału do dalszego różnicowania, od komórek totipotencjalnych (zygota), poprzez pluripotencjalne (komórki zarodkowe) do multipotencjalnych lub unipotencjalnych (komórki somatyczne). Zarodkowe komórki macierzyste, z uwagi na nieograniczone zdolności namnażania i pluripotencjalność wydają się najbardziej optymalne do zastosowania w terapiach regeneracyjnych, lecz zastrzeżenia natury etyczno-moralnej pozyskiwania tych komórek, a także możliwość ich niekontrolowanej proliferacji po przeszczepieniu w organizmie biorcy skłoniły badaczy do poszukiwania alternatywnych źródeł komórek macierzystych, jakimi są tkanki dojrzałego organizmu. Badania ostatnich lat wykazały, iż w dojrzałych tkankach somatycznych znajdują się pluripotencjalne komórki macierzyste, co więcej odkrycia Takahashi i Yamanaka w roku 2006 r udokumentowały możliwość przekształcenia zróżnicowanych komórek izolowanych od osobników dorosłych w komórki pluripotencjalne. Zainicjowanie nowatorskich metod badawczych, których celem będzie opracowanie skutecznych sposobów przeszczepiania somatycznych komórek macierzystych w celach regeneracyjnych jest nadzieją w terapii wielu nieuleczalnych schorzeń.
Źródło:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii; 2012, 1
2082-9256
Pojawia się w:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Organismal view of a plant and a plant cell.
Autorzy:
Wojtaszek, Przemysław
Powiązania:
https://bibliotekanauki.pl/articles/1044138.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cell wall
plant cell
organismal theory
plant
cell theory
apoplast
Opis:
Cell walls are at the basis of a structural, four-dimensional framework of plant form and growth time. Recent rapid progress of cell wall research has led to the situation where the old, long-lasting juxtaposition: "living" protoplast - "dead" cell wall, had to be dropped. Various attempts of re-interpretation cast, however, some doubts over the very nature of plant cell and the status of the walls within such a cell. Following a comparison of exocellular matrices of plants and animals, their position in relation to cells and organisms is analysed. A multitude of perspectives of the biological organisation of living beings is presented with particular attention paid to the cellular and organismal theories. Basic tenets and resulting corollaries of both theories are compared, and evolutionary and developmental implications are considered. Based on these data, "The Plant Body" - an organismal concept of plants and plant cells is described.
Źródło:
Acta Biochimica Polonica; 2001, 48, 2; 443-451
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cell compound of parenchyma and extracellular matrices of Triaenophorus nodulosus [Cestoda] in ontogenesis
Autorzy:
Korneva, J.V.
Powiązania:
https://bibliotekanauki.pl/articles/841015.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Triaenophorus nodulosus
Cestoda
cell forming
ontogenesis
life cycle
muscle cell
cell compound
tegument cell
parenchyma
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The mucosal mast cell and IgA plasma cell responses to primary Trichinella spiralis infection in BALB-c mice treated with ketotifen
Autorzy:
Doligalska, M
Laskowska, M.
Powiązania:
https://bibliotekanauki.pl/articles/836928.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
ketotifen
plasma cell
mucosal mast cell
mouse
infection
mice
mast cell
inflammation
Trichinella spiralis
Opis:
The effect of ketotifen on inflammation in the intestine during T. spiralis infection in BALB/c mice was examined. The lack of enteropathy in treated mice was accompanied to affected the size of worms and the number of worms, but did not prevent the retardation of nematodes in the intestine. Fecundity of females in vitro and the number of muscle larvae were not statistically changed after treatment. Ketotifen reduced the number of mast cells and IgA plasma cells in the intestine. As inflammatory influx, epithelial damage and IgA response are related to the action of T cells, ketotifen affected T dependent reactions in the gut of T. spiralis infected mice.
Źródło:
Annals of Parasitology; 2001, 47, 4
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Theory of Red Blood Cell Oscillations in an Ultrasound Field
Autorzy:
Johansen, K.
Kimmel, E.
Postema, M.
Powiązania:
https://bibliotekanauki.pl/articles/178064.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
spatio-temporal cell dynamics
Rayleigh-Plesset equation
spherical cell
red blood cell
erythrocyte
sonophore
Opis:
Manipulating particles in the blood pool with noninvasive methods has been of great interest in therapeutic delivery. Recently, it was demonstrated experimentally that red blood cells can be forced to translate and accumulate in an ultrasound field. This acoustic response of the red blood cells has been attributed to sonophores, gas pockets that are formed under the influence of a sound field in the inner-membrane leaflets of biological cells. In this paper, we propose a simpler model: that of the compressible membrane. We derive the spatio-temporal cell dynamics for a spherically symmetric single cell, whilst regarding the cell bilayer membrane as two monolayer Newtonian viscous liquids, separated by a thin gas void. When applying the newly-derived equations to a red blood cell, it is observed that the void inside the bilayer expands to multiples of its original thickness, even at clinically safe acoustic pressure amplitudes. For causing permanent cell rupture during expansion, however, the acoustic pressure amplitudes needed would have to surpass the inertial cavitation threshold by a factor 10. Given the incompressibility of the inner monolayer, the radial oscillations of a cell are governed by the same set of equations as those of a forced antibubble. Evidently, these equations must hold for liposomes under sonication, as well.
Źródło:
Archives of Acoustics; 2017, 42, 1; 121-126
0137-5075
Pojawia się w:
Archives of Acoustics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hypothesis: cell volume limits cell divisions
Autorzy:
Biliński, Tomasz
Bartosz, Grzegorz
Powiązania:
https://bibliotekanauki.pl/articles/1041184.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
replicative aging
Saccharomyces cerevisiae
cell volume
yeast
Opis:
Mammalian somatic cells and also cells of the yeast Saccharomyces cerevisiae are capable of undergoing a limited number of divisions. Reaching the division limit is referred to, apparently not very fortunately, as replicative aging. A common feature of S. cerevisiae cells and fibroblasts approaching the limit of cell divisions in vitro is attaining giant volumes. In yeast cells this phenomenon is an inevitable consequence of budding so it is not causally related to aging. Therefore, reaching a critically large cell volume may underlie the limit of cell divisions. A similar phenomenon may limit the number of cell divisions of cultured mammalian cells. The term replicative (generative) aging may be therefore illegitimate.
Źródło:
Acta Biochimica Polonica; 2006, 53, 4; 833-835
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mathematical model for biological cell deformation in a cylindrical pore
Autorzy:
Szwast, M.
Suchecka, T.
Piątkiewicz, W.
Powiązania:
https://bibliotekanauki.pl/articles/185778.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
deformacja komórek
czerwone krwinki
cell deformation
red blood cell
cell stamina
Opis:
Some studies show that cells are able to penetrate through pores that are smaller than cell size. It concerns especially Red Blood Cells but it also may concern different types of biological cells. Such penetration of small pores is a very significant problem in the filtration process, for example in micro or ultrafiltration. Deformability of cells allows them to go through the porous membrane and contaminate permeate. This paper shows how cells can penetrate small cylindrical holes and tries to assess mechanical stress in a cell during this process. A new mathematical approach to this phenomenon was presented, based on assumptions that were made during the microscopic observation of Red Blood Cell aspiration into a small capillary. The computational model concerns Red Blood Cell geometry. The mathematical model allows to obtain geometrical relation as well as mechanical stress relations.
Źródło:
Chemical and Process Engineering; 2012, 33, 3; 385-396
0208-6425
2300-1925
Pojawia się w:
Chemical and Process Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Skin of sailor: cutis rhomboidalis nuchae, actinic keratosis, squamous cell carcinoma and basal cell carcinoma. Case report
Autorzy:
Abdulaziz, Ahmad
Brzeziński, Piotr
Chiriac, Anca
Powiązania:
https://bibliotekanauki.pl/articles/1065852.pdf
Data publikacji:
2014
Wydawca:
Medical Education
Tematy:
actinic keratosis
basal cell carcinoma
sailor
squamous cell carcinoma
ultraviolet
Opis:
Chronic exposure to environmental ultraviolet radiation (UVR) plays a key role both in photocarcinogenesis and induction of accelerated skin ageing. Sailors commonly experience a significant number of cutaneous problems, related to the exposure to environmental factors due to their working conditions. Among these factors, sun exposure is able to determine both acute and chronic skin damage, mostly linked to the effects of the ultraviolet (UV) radiation on epidermal and dermal structures. We report a case of sailor with cutis rhomboidalis nuchae, solar elastosis, actinic keratosis (AK), numerous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) of the head and trunk.
Źródło:
OncoReview; 2014, 4, 1; A37-41
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Systemy Cell-on-a-chip jako zaawansowane modele hodowli komórek in vitro
Cell-on-a-chip systems as advanced cell culture models
Autorzy:
Jastrzębska, Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/172363.pdf
Data publikacji:
2019
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
Cell-on-a-chip
mikrosystem
sferoidy
hydrożel
hodowla komórek
zaawansowany model in vitro
microsystem
spheroids
hydrogel
cell cultures
advanced in vitro model
Opis:
In vitro study at the cellular level is an important step in evaluation of biological properties of newly developed drugs. In addition, thanks to the use of cell cultures, it is possible to study the function of the cells of a specific tissue and to mimic the conditions of cell growth or disease state. Standard (conventional) cell cultures are most often based on monolayer (two-dimensional, 2D) culture. In such culture, the cells adhere to the surface of the bottle/plate in which they grow. Nevertheless, spatial (three-dimensional, 3D) cultures are also increasingly used in culture research. However, conventional cell cultures still have a limited ability to mimic the natural environment of cell growth. Lab-on-a-chip systems (called Cell-on-a-chip) are new miniature constructional and methodical solutions useful for in vitro cell cultures. Microsystems allow the development of more advanced cell models than standard in vitro cultures so far used in biological laboratories. Thanks to this, it is possible to study cell functions under conditions that mimic the natural environment of cell growth. It should be emphasized, that the microsystems cannot completely replace animal testing. Cell-on-a-chip systems can provide alternative or complementary solutions / tools for in vivo tests, while ensuring high reliability of the obtained results. So far, Lab-on-a-chip systems have been used to assess the cytotoxicity of compounds, model intercellular interactions and mimic the function of various tissues. In this article we describe Cell-on-a-chip systems which can be used as advanced models of cell cultures. At the beginning of the manuscript, Cell-on-a- chip systems and materials used for fabrication microsystems are characterized. Next, the microsystems used as platforms for cytotoxicity study are presented. A special attention has been paid to Cell-on-a-chip for spatial cell cultures using: spheroids, hydrogels, multilayers and nanoscaffolds. Finally, Organ-on-a-chip systems are shortly discussed. Schemes of Cell-on-a-chip system, types of cell cultures obtained in microscale are presented in the article. A table showing a construction materials is also added. At the end, the article is summarized.
Źródło:
Wiadomości Chemiczne; 2019, 73, 11-12; 715-735
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Temperature Effect on Performance of Different Solar Cell Technologies
Autorzy:
Adeeb, Jehad
Farhan, Alaa
Al-Salaymeh, Ahmed
Powiązania:
https://bibliotekanauki.pl/articles/124356.pdf
Data publikacji:
2019
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
solar cell
photovoltaics
temperature effect
multicrystalline silicon solar cell
amorphous silicon solar cell
monocrystalline
Opis:
One of the main parameters that affect the solar cell performance is cell temperature; the solar cell output decreases with the increase of temperature. Therefore, it is important to select the proper solar cell technology that performs better at a specified location considering its average temperatures. In addition, the solar cell performance is directly reflected on the overall economics of the project. This paper is proposed to evaluate the variations in the performance of different solar cell technologies related to the temperature in Amman, Jordan. Field data of weather station and three PV systems (Poly-crystalline, Mono-crystalline and Thin-film) of identical design parameters were collected from Test Field Project at Applied Science Private University, Shafa Badran, Amman, Jordan. These data were analysed in the following way. estimated specific energy yield (kWh/kWp) for the three different PV systems was calculated depending on the measured value of solar irradiance and technical specifications of the installed solar panels and inverters, then the actual energy yield at different temperatures over one year was compared with the estimated value, so the deviations could be determined and actual temperature coefficients for energy yield could be calculated, knowing that the three PV Systems have identical design parameters (tilt angle, azimuth angle, type and dimensions of mounting structure and inverter size) and same cleaning method and schedule. It was found that the thin-film solar panels are less affected by temperature with temperature coefficient of -0.0984%, and -0.109%, -0.124% for Mono-crystalline and Poly-crystalline respectively. These results can be implemented in the preliminary design steps, specifically in the selection of the solar cell technology to be installed in a specific location.
Źródło:
Journal of Ecological Engineering; 2019, 20, 5; 249-254
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Reduced expression of E-cadherin and increased sialylation level in clear cell renal cell carcinoma
Autorzy:
Borzym-Kluczyk, Małgorzata
Radziejewska, Iwona
Cechowska-Pasko, Marzanna
Darewicz, Barbara
Powiązania:
https://bibliotekanauki.pl/articles/1038588.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
clear cell renal cell carcinoma
E-cadherin
lectins
sialyl Lewis antigens
Opis:
Cancer cells are characterized by an aberrant increase in protein N-glycosylation and by disruption of E-cadherin-mediated adherens junctions. However, the relationship between alterations in N-glycosylation process and loss of E-cadherin adhesion in cancer remains unclear. The mechanisms of altered expression of adhesive glycoproteins in cancer cells have not been fully elucidated. Thus, the aim of this study was to examine the expression of E-cadherin and sialyl Lewisa/x, NeuAcα2-3Gal, NeuAcα2-6Gal/GalNAc structures in the normal renal tissue and intermediate and cancerous tissues from patients with clear cell RCC. Moreover, we attempted to correlate the E-cadherin expression with some specific sugar residues of renal cancer tissue glycoproteins. The expression of E-cadherin was analysed using ELISA test and immunoblotting. Oligosaccharide structures and sialylation level were detected with ELISA test using specific biotinylated lectins or antibodies. A significant decrease of E-cadherin expression as well as a significant increase in sialylated oligosaccharides level in intermediate zone and renal cancer tissue in comparison to normal renal tissue are reported. Significant decrease in expression of cadherins and increase in sialylation of oligosaccharide structures in renal cancer tissue in comparison to normal renal tissue, and in renal cancer tissue in comparison to intermediate zone of renal tissue, are important for the future research concerning detection and quantification of cadherins and sialylated oligosaccharide structures in urine and cells of urinary sediment as possible non-invasive marker of early RCC.
Źródło:
Acta Biochimica Polonica; 2017, 64, 3; 465-470
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Particle-in-Cell electrostatic numerical algorithm
Algorytm numeryczny Particle-in-Cell dla problemu elektrostatycznego
Autorzy:
Konior, W.
Powiązania:
https://bibliotekanauki.pl/articles/212864.pdf
Data publikacji:
2017
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Lotnictwa
Tematy:
plasma
neutral particles
Particle-In-Cell
Monte-Carlo method
plazma
heliosfera
Particle-in-Cell
Monte-Carlo
Opis:
Existing global models of interaction between the solar wind (SW) and the local interstellar medium (LISM) describe the heliosphere that arises as a result of this interaction. There is a strong motivation to develop a kinetic model using the Particle-in-Cell (PIC) method to describe phenomena which appear in the heliosphere. This is however a long term scientific goal. This paper describes an electrostatic Particle-in-Cell numerical model developed in the Institute of Aviation in Warsaw, winch includes mechanical and charge exchange collisions between particles in the probabilistic manner using Direct Simulation Monte Carlo method. This is the first step into developing simulations of the heliosphere incorporating kinetic effects in collisionless plasmas. In this paper we focus only on presenting the work, which have been done on the numerical PIC algorithm.
Istniejące globalne modele oddziaływania wiatru słonecznego (SW) z lokalną materią międzygwiazdową (LISM) opisują heliosferę, która powstaje w wyniku interakcji tych dwóch ośrodków. Istnieje silna motywacja do opracowania modelu kinetycznego wykorzystującego metodę Particle-in-Cell (PIC) w celu opisu zjawisk, które zachodzą w heliosferze. Jednakże jest to długoterrninowy cel naukowy. W artykule przedstawiono elektrostatyczny model numeryczny PIC. opracowany w Instytucie Lotnictwa w Warszawie, który obejmuj e kolizje mechaniczne i rezonansową wymianę ładunków pomiędzy cząstkami w sposób probabilistyczny metodą Direct Simulation Monte Carlo. Jest to pierwszy krok w opracowywaniu symulacji heliosfery zawierającej efekty kinetyczne w plazmach bezzderzeniowych. W tym artykule koncentrujemy się tylko na prezentowaniu prac, które zostały wykonane z wykorzystaniem algorytmu numerycznego PIC.
Źródło:
Prace Instytutu Lotnictwa; 2017, 3 (248); 24-45
0509-6669
2300-5408
Pojawia się w:
Prace Instytutu Lotnictwa
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Stress distribution in cell wall – inferring stress anisotropy from the pattern of buckling in the innermost cell wall layer
Autorzy:
Borowska-Wykret, D.
Powiązania:
https://bibliotekanauki.pl/articles/79982.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
stress distribution
cell wall
anisotropy
tensile stress
hyperosmotic condition
epidermis cell
tissue stress
cellulose microfibril
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Toxoplasma gondii and the host cells
Autorzy:
Dlugonska, H.
Powiązania:
https://bibliotekanauki.pl/articles/6614.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Toxoplasma gondii
host cell
host barrier
dendritic cell
muscle cell
Protozoa
parasite
mammal
bird
prevalence
Opis:
The protozoan Toxoplasma gondii, described by Nicolle and Manceaux in 1908, is a ubiquitous and cosmopolitan parasite that infects a wide range of mammal and bird species with high prevalence. The biological success of T. gondii is associated with the formation of a specific relationship between the parasite and host cells leading to the establishment of a latent, chronic infection. During primary infection, acquired mostly by the oral route, the quickly multiplying tachyzoites disseminate through the body crossing several structural-functional barriers as bloodbrain or blood-retina, then they transform into dormant bradyzoites which, enclosed in tissue cysts, occupy preferentially the brain, skeletal muscle and eye. Although T. gondii is able to infect all kinds of nucleated cells, it uses strictly defined host cells, dependent on the life-cycle phase and infection stage. The article discusses selected aspects of the parasite passing via the host body barriers as well as particular role of dendritic cells and skeletal muscle cells, used by the parasite as an very effective vehicle to disseminate throughout the host body or the site of long-term T. gondii persistence, respectively.
Źródło:
Annals of Parasitology; 2014, 60, 2
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Creating cell vaults
Kształtowanie kryształowych sklepień
Autorzy:
Vogt, B.
Flaga, Ł.
Powiązania:
https://bibliotekanauki.pl/articles/119217.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Geometrii i Grafiki Inżynierskiej
Tematy:
cell vault
vault elevation
structure joint
joint level
cell structure
sklepienie kryształowe
wysokość sklepienia
węzeł struktury
poziom węzła
Opis:
The cell vaulting, which has been present in architecture since the half of the 15th century, has seen a renaissance lately. It owes its popularity to the great variety of roof structures it offers, with respect to both, its architecture and construction. The most important factors in creating cell vaults are the number of divisions and the height of joint level of a given structure. In this paper we would like to present the geometrical methods of creating cell vaults.
Sklepienia kryształowe występujące w architekturze od połowy XV wieku w ostatnim okresie zaczynają mieć swój renesans, gdyż oferują niezwykle dużą różnorodność przekryć, tak pod względem konstrukcyjnym jak i architektonicznym. Ich kształtowanie jest oparte o ilość podziałów oraz ustalenie wysokości poziomów węzłów struktury. W tej publikacji staramy się pokazać geometryczne sposoby ich kształtowania.
Źródło:
Journal Biuletyn of Polish Society for Geometry and Engineering Graphics; 2007, 17; 66-71
1644-9363
Pojawia się w:
Journal Biuletyn of Polish Society for Geometry and Engineering Graphics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The xCELLigence system for real-time and label-free analysis of neuronal and dermal cell response to Equine Herpesvirus type 1 infection
Autorzy:
Golke, A.
Cymerys, J.
Slonska, A.
Dzieciatkowski, T.
Chmielewska, A.
Tucholska, A.
Banbura, M.W.
Powiązania:
https://bibliotekanauki.pl/articles/30665.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
xCELLigence system
real-time analysis
label-free analysis
neuronal cell response
dermal cell response
cell response
equine herpesvirus 1
animal infection
herpesvirus
neuron
neuronal cell
dermal cell
Opis:
Real-time cell electronic sensing (RT-CES) based on impedance measurements is an emerging technology for analyzing the status of cells in vitro. It allows label-free, real time monitoring of the biological status of cells. The present study was designed to assess dynamic data on the cell processes during equine herpesvirus type 1 (EHV-1) infection of ED (equine dermal) cells and primary murine neuronal cell culture. We have demonstrated that the xCELLigence system with dynamic monitoring can be used as a rapid diagnostic tool both to analyze cellular behavior and to investigate the effect of viral infection.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nanostructure of natural and model cell wall materials
Autorzy:
Cybulska, J.
Konstankiewicz, K.
Zdunek, A.
Skrzypiec, K.
Powiązania:
https://bibliotekanauki.pl/articles/25202.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Instytut Agrofizyki PAN
Tematy:
plant tissue
cell wall
nanostructure
apple
natural material
model material
cell wall material
parenchyma cell
mechanical property
polysaccharide network
Źródło:
International Agrophysics; 2010, 24, 2; 107-114
0236-8722
Pojawia się w:
International Agrophysics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Novel designs and technologies for cell engineering
Autorzy:
Ziółkowska, K.
Chudy, M.
Dybko, A.
Brzózka, Z.
Powiązania:
https://bibliotekanauki.pl/articles/115526.pdf
Data publikacji:
2011
Wydawca:
Fundacja na Rzecz Młodych Naukowców
Tematy:
lab-on-a-chip
multicellular tumor spheroid
cancer
in vitro cell culture
cell engineering
Opis:
Microfluidic devices, such as lab-on-a-chip systems, are highly advantageous for cell engineering and cell based assays. It is a particularly useful approach for development of the in vitro cellular systems mimicking the in vivo environment. In this paper, a novel lab-on-a-chip device for three-dimensional human cell culture and anticancer drug testing is presented. Cells were cultured as Multicellular Tumor Spheroids (MCTS) — the best cancer tumor model developed so far. Diff erent designs were tested and novel technique of microfabrication in poly(dimethylsiloxane) was developed. MCTS were cultured in a system of polymeric microwells, with the network of microfluidic channels for culture medium flow. Design included optimal shear stress and proper nutrients supply for cultured cells. Final design provided MCTS culture for four weeks with the homeostasis-like state achievement, which is characteristic for the in vivo situation.
Źródło:
Challenges of Modern Technology; 2011, 2, 4; 54-60
2082-2863
2353-4419
Pojawia się w:
Challenges of Modern Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Merkel cell carcinoma
Autorzy:
Markiewicz, Jarosław
Dziewirski, Wirginiusz
Powiązania:
https://bibliotekanauki.pl/articles/1065725.pdf
Data publikacji:
2014
Wydawca:
Medical Education
Tematy:
Merkel cell carcinoma
cutaneous neuroendocrine carcinoma
therapy
Opis:
Merkel cell carcinoma (MCC) is a rare cutaneous malignancy, with aggressive behaviour. The discovery of MCC polyomavirus (MCPyV) provided a major insight into pathogenesis of MCC, as MCPyV is present in most MCC tumours. The primary treatment of locoregional MCC is surgery, and sentinel lymph node biopsy should be performed in all cases at clinical stage I-II. Adjuvant radiotherapy decreases disease recurrences in stage I-III of the disease. Chemotherapy is primarily used for palliation and provides overall response rates of approximately 70%; however, the disease often recurs within a few months. All cases of MCC should be managed in an experienced multidisciplinary setting.
Źródło:
OncoReview; 2014, 4, 3; A121-125
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simple method to estimate cell wall extensibility coefficient by using only two cardinal numbers
Autorzy:
Pietruszka, M
Powiązania:
https://bibliotekanauki.pl/articles/58740.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Botaniczne
Tematy:
cell wall
plant cell
growing plant
temperature
extensibility coefficient
Opis:
In this short communication we consider the extensibility properties of the cell wall. This is accomplished by a heuristically motivated equation for the expanding volume of the cell. The experimentally determined characteristic time t0 and temperature T0 are the only numbers required for evaluating the effective yielding coefficient Ф(t, T) in the respective time and temperature domains.
Źródło:
Acta Societatis Botanicorum Poloniae; 2009, 78, 4; 269-270
0001-6977
2083-9480
Pojawia się w:
Acta Societatis Botanicorum Poloniae
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selection of frost-tolerant cell lines from cell cultures of Solanum tuberosum L.
Autorzy:
Anjum, Muhammad Akbar
Powiązania:
https://bibliotekanauki.pl/articles/2198823.pdf
Data publikacji:
2001-06-21
Wydawca:
Instytut Hodowli i Aklimatyzacji Roślin
Tematy:
potato
Solanum
cell culture
proline
hydoxyproline resistance
frost tolerance
Opis:
Fourteen hydroxyproline-resistant cell lines were selected by plating 7 days old cell suspensions of Solanum tuberosum L. cvs. Desiree and Maris Piper on a cell plating medium containing 5 or 10 mM hydroxyproline (hyp). Cell suspensions were either plated directly on selective media or after mutagenic treatment with gamma rays at a dose of 20 Gy or after freezing to –6°C. The frequency of resistant colonies varied from 0.15 to 0.35 x 10-6. Almost all the selected lines possessed increased levels of frost tolerance as compared to their non-selected controls except one indicating that hyp resistance and frost tolerance are not necessarily linked.
Źródło:
Plant Breeding and Seed Science; 2001, 45, 1; 3-10
1429-3862
2083-599X
Pojawia się w:
Plant Breeding and Seed Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Metastasis of clear cell renal cell carcinoma to the organs of the head and neck – an ongoing problem
Autorzy:
Torchalla, Patrycja
Czesak, Małgorzata
Osuch-Wójcikiewicz, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1398949.pdf
Data publikacji:
2021
Wydawca:
Index Copernicus International
Tematy:
clear cell renal cancer
renal cell carcinoma
metastases
submandibular salivary gland
Opis:
Renal cell carcinoma accounts for about 2-3% of all malignancies. It is characterized by a high frequency of metastases, which are most often observed in the lungs, bones, liver, brain and regional lymph nodes. Literature highlights the rare occurrence of renal cancer metastases to the head and neck, even though it is the third most common cancer that metastasizes to the head and neck. Below we present a case report of metastases of clear cell carcinoma from a kidney to the organs of the head and neck. The analysis was carried out retrospectively based on medical records of a patient hospitalized at the Department of Otorhinolaryngology, Head and Neck Surgery of the Medical University of Warsaw in the years 2009-2019. We describe an 81-year-old man after left-sided nephrectomy due to clear cell carcinoma, with numerous distant metastases, who was diagnosed with metastases to the left submandibular salivary gland 8 years after primary surgery, followed by a diagnosis of metastasis to the right submandibular salivary gland 3 years later. The patient underwent 2 radical procedures to remove the submandibular salivary glands. Due to the presence of lung metastases, treatment with a tyrosine kinase inhibitor was also implemented.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2021, 10, 1; 42-48
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An Application of General Branching Processes to a Cell Cycle model With Two Uncoupled Subcycles and Unequal Cell Division
Autorzy:
Alexandersson, M.
Powiązania:
https://bibliotekanauki.pl/articles/929755.pdf
Data publikacji:
2000
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
proces cykliczny komórki
matematyka
branching process
cell cycle model
unequal cell division
stable type distribution
alpha-curve
beta-curve
mother-daughter correlation
Opis:
A cell population model is constructed and analysed in the frameworkof general branching process theory. The model uses the idea that the DNA division cycle and the cell growth cycle are loosely coupled. The cell division is assumed to be unequal and the structure variables of the modelare size and growth, where the growth is regulated by supramitotic growth control. An explicit expression for the stable birth type distributionis given and asymptotics, such as the alpha- and beta_1-curve and various size distributions, are derived. We also prove that the microheterogeneity ingrowth causes the mother-daughter life length correlation to be non-negative.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2000, 10, 1; 131-145
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Oxidative stress induced autophagic cell death in plants
Autorzy:
Minibayeva, F.
Ryabovol, V.
Ponomareva, A.
Dmitrieva, S.
Sulkarnayeva, A.
Powiązania:
https://bibliotekanauki.pl/articles/79946.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
oxidative stress
cell death
autophagy
transmission electron microscopy
plant cell
disruption
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Thermodynamics of irreversible plant cell growth
Autorzy:
Pietruszka, M
Lewicka, S.
Pazurkiewicz-Kocot, K.
Powiązania:
https://bibliotekanauki.pl/articles/58662.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Botaniczne
Tematy:
thermodynamics
irreversible process
plant cell
plant growth
cell wall
yielding
growth stimulator
growth inhibitor
modified growth equation
Opis:
The time-irreversible cell enlargement of plant cells at a constant temperature results from two independent physical processes, e.g. water absorption and cell wall yielding. In such a model cell growth starts with reduction in wall stress because of irreversible extension of the wall. The water absorption and physical expansion are spontaneous consequences of this initial modification of the cell wall (the juvenile cell vacuolate, takes up water and expands). In this model the irreversible aspect of growth arises from the extension of the cell wall. Such theory expressed quantitatively by time-dependent growth equation was elaborated by Lockhart in the 60's.The growth equation omit however a very important factor, namely the environmental temperature at which the plant cells grow. In this paper we put forward a simple phenomenological model which introduces into the growth equation the notion of temperature. Moreover, we introduce into the modified growth equation the possible influence of external growth stimulator or inhibitor (phytohormones or abiotic factors). In the presence of such external perturbations two possible theoretical solutions have been found: the linear reaction to the application of growth hormones/abiotic factors and the non-linear one. Both solutions reflect and predict two different experimental conditions, respectively (growth at constant or increasing concentration of stimulator/inhibitor). The non-linear solution reflects a common situation interesting from an environmental pollution point of view e.g. the influence of increasing (with time) concentration of toxins on plant growth. Having obtained temperature modified growth equations we can draw further qualitative and, especially, quantitative conclusions about the mechanical properties of the cell wall itself. This also concerns a new and interesting result obtained in our model: We have calculated the magnitude of the cell wall yielding coefficient (T) [m3 J-1•s-1] in function of temperature which has acquired reasonable numerical value throughout.
Źródło:
Acta Societatis Botanicorum Poloniae; 2006, 75, 3; 183-190
0001-6977
2083-9480
Pojawia się w:
Acta Societatis Botanicorum Poloniae
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-25 z 1738

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