- Tytuł:
- Assessment of buccal mucosa genotoxicity in insecticide-exposed urban fumigators in Cali, Colombia
- Autorzy:
-
Londoño-Velasco, Elizabeth
Asencio-Santofimio, Helberg
Ortega-Avila, Jose G.
Rosero-Caldón, Aldair B.
Aristizabal-Grisales, Juan C.
Rey-Henao, Laura
Vargas-Rivera, Jairo A.
Vergara-Escudero, Enrique - Powiązania:
- https://bibliotekanauki.pl/articles/28762056.pdf
- Data publikacji:
- 2024-03-05
- Wydawca:
- Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
- Tematy:
-
insecticides
occupational exposure
buccal micronucleus cytome assay
DNA damage
biomarker
personal protective equipment - Opis:
- Objectives This study aimed to evaluate cytogenetic damage in the buccal mucosa of non-exposed subjects (N = 33) and insecticide-exposed fumigators (N = 31) in the urban area of Cali, Colombia. Material and Methods Through a questionnaire sociodemographic data, anthropometric measurements, state of health, and lifestyle were collected. Buccal micronucleus cytome (BMCyt) assay was using for evaluate cytogenetic damage. Results The study showed that all fumigators used adequate personal protective equipment (PPE) and had low alcohol consumption. The authors did not find significant differences in BMCyt biomarkers between the groups (p > 0.05). Multivariate analysis showed a 13% increase in micronucleus (MN) frequency for every year of increasing age (OR = 1.13, p = 0.029), and higher MN with the decrease in daily fruit consumption (OR = 4.71, p = 0.084), without statistical significance. Conclusions The results between groups could be related to healthy habits and PPE use among the subjects.
- Źródło:
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International Journal of Occupational Medicine and Environmental Health; 2024, 37, 1; 128-137
1232-1087
1896-494X - Pojawia się w:
- International Journal of Occupational Medicine and Environmental Health
- Dostawca treści:
- Biblioteka Nauki
Artykuł