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Wyszukujesz frazę "T-cell" wg kryterium: Wszystkie pola


Tytuł:
Effectiveness of current technology in GHG reduction – A literature survey
Autorzy:
Klakeel, T.
Anantharaman, M.
Islam, R.
Garaniya, V.
Powiązania:
https://bibliotekanauki.pl/articles/24201381.pdf
Data publikacji:
2023
Wydawca:
Uniwersytet Morski w Gdyni. Wydział Nawigacyjny
Tematy:
effectiveness evaluation
greenhouse gas
literature review
marine environment
IMO guidelines
hydrogen fuel cell
heavy fuel oil
energy efficiency design index
Opis:
In 2018 during the 72nd session of the Maritime Environmental Protection Committee (MEPC) IMO adopted its initial strategy for the reduction of greenhouse gas emissions (GHG) from the ships to meet the Paris Agreement Goals, 2015. This is considered as a major milestone in formulizing a clear strategy by IMO towards its objective of reducing the global GHG emissions from the ships. The strategy had two primary objectives: the first was to decrease total annual GHG emissions by at least 50% by 2050 compared to 2008 levels. The second objective was to promote the phasing out of GHG emissions entirely. In 2020, the International Maritime Organization (IMO) conducted a study which revealed that greenhouse gas (GHG) emissions from shipping had increased by 9.6%. The rise in global maritime trade was identified as the main factor behind this increase. IMO's 2020 study also concluded that reducing GHG emissions by focusing only on energy-saving technologies and ship speed reduction would not be enough to meet the IMO's 2050 GHG reduction target. Therefore, greater attention needs to be given to the use of low-carbon alternative fuels. To understand the effectiveness of currently available technologies in reducing GHG emissions from ships, a literature survey was conducted in this study. The survey examined a range of related articles published between 2018 and 2022. This study aimed to identify the current stage and the quantity of literature available on various technologies and, more importantly, serve as a decision-making support tool for selecting a technology under specific circumstances in a quantitative manner. The technologies were divided into four groups: those that utilize fossil fuels, those that use renewable energy, those that use fuel cells, and those that use low-carbon or alternative fuels. The literature survey was conducted using Web of Science (WoS) and Google Scholar. The results of this study will also help to identify clear research gaps in comparing the effectiveness of various available technologies to reduce GHG emissions. Ultimately, the aim is to develop a comprehensive strategy that can be used to reduce GHG emissions from shipping and contribute to the global fight against climate change.
Źródło:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation; 2023, 17, 1; 171--176
2083-6473
2083-6481
Pojawia się w:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
On the analysis of a mathematical model of CAR-T cell therapy for glioblastoma: Insights from a mathematical model
Autorzy:
Bodnar, Marek
Foryś, Urszula
Piotrowska, Monika J.
Bodzioch, Mariusz
Romero-Rosales, Jose A.
Belmonte-Beitia, Juan
Powiązania:
https://bibliotekanauki.pl/articles/24200684.pdf
Data publikacji:
2023
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
glioblastoma
CAR-T cell therapy
mathematical modelling
periodic treatment
glejak wielopostaciowy
terapia CAR-T
modelowanie matematyczne
Opis:
Chimeric antigen receptor T (CAR-T) cell therapy has been proven to be successful against different leukaemias and lymphomas. Its success has led, in recent years, to its use being tested for different solid tumours, including glioblastoma, a type of primary brain tumour, characterised by aggressiveness and recurrence. This paper presents an analytical study of a mathematical model describing the competition of CAR-T and glioblastoma tumour cells, taking into account their immunosuppressive capacity. The model is formulated in a general way, and its basic properties are investigated. However, most of the analysis considers the model with exponential tumour growth, assuming this growth type for simplicity. The existence and stability of steady states are studied, and the subsequent focus is on two different types of treatment: constant and periodic. Finally, protocols for CAR-T cell therapy of glioblastoma are numerically derived; these are aimed at preventing the tumour from reaching a critical size and at prolonging the patients’ survival time as much as possible. The analytical and numerical results provide theoretical support for the treatment of glioblastoma using CAR-T cells.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2023, 33, 3; 379--394
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Experimental Study of Temperature Influence on the Performance of PV/T Cell under Jordan Climate Conditions
Autorzy:
Al-Odat, Mohammed Qassim
Powiązania:
https://bibliotekanauki.pl/articles/2202185.pdf
Data publikacji:
2022
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
PV module
electrical conversion
electrical efficiency
water cooling
cooling
cell temperature
Opis:
The electrical performance and the productivity of PV module depend on two main parameters, i.e. the radiation intensity and the cell operating temperature. The module electrical efficiency and productivity are significantly reduced as its temperature increases. Accordingly, cooling of PV modules is one of the most effective techniques to obtain higher efficiency and productivity as well as to reduce the degradation modes of PV modules due to high temperatures. This research work presents an experimental study carried out to investigate the effect of PV module cooling on the performance of PV module under Irbid city (Jordan) climate conditions. It was found that the electrical efficiency and the productivity of the PV modules were approximately enhanced by 14%. Therefore, water cooling of the PV modules is essential to enhance their performance.
Źródło:
Journal of Ecological Engineering; 2022, 23, 10; 80--88
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Low Leakage and Robust Sub-threshold SRAM Cell Using Memristor
Autorzy:
Mustaqueem, Zeba
Ansari, Abdul Quaiyum
Akram, Md Waseem
Powiązania:
https://bibliotekanauki.pl/articles/2200681.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
6T SRAM cell
memristor
power dissipation
read and write operation
leakage current
stability
non-volatile circuit
Opis:
This work aims to improve the total power dissipation, leakage currents and stability without disturbing the logic state of SRAM cell with concept called sub-threshold operation. Though, sub-threshold SRAM proves to be advantageous but fails with basic 6T SRAM cell during readability and writability. In this paper we have investigated a non-volatile 6T2M (6 Transistors & 2 Memristors) sub-threshold SRAM cell working at lower supply voltage of VDD=0.3V, where Memristor is used to store the information even at power failures and restores previous data with successful read and write operation overcomes the challenge faced. This paper also proposes a new configuration of non-volatile 6T2M (6 Transistors & 2 Memristors) subthreshold SRAM cell resulting in improved behaviour in terms of power, stability and leakage current where read and write power has improved by 40% and 90% respectively when compared to 6T2M (conventional) SRAM cell. The proposed 6T2M SRAM cell offers good stability of RSNM=65mV and WSNM=93mV which is much improved at low voltage when compared to conventional basic 6T SRAM cell, and improved leakage current of 4.92nA is achieved as compared.
Źródło:
International Journal of Electronics and Telecommunications; 2022, 68, 4; 667--676
2300-1933
Pojawia się w:
International Journal of Electronics and Telecommunications
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Syndrome of inappropriate secretion of ADH in the course of chemotherapy for anaplastic large T-cell lymphoma of the lung
Autorzy:
Kade, Grzegorz
Michalak, Maciej
Straszyńska, Aleksandra
Moczulski, Dariusz
Hałka, Janusz
Spaleniak, Sebastian
Powiązania:
https://bibliotekanauki.pl/articles/2159011.pdf
Data publikacji:
2022-06-30
Wydawca:
Medical Education
Tematy:
SIADH
hyponatremia
lymphoma
antineoplastic drugs
Opis:
The present study reports the case of a 40-year-old patient who presented SIADH syndrome due to anaplastic large T-cell lymphoma and antineoplastic drugs.
Źródło:
OncoReview; 2022, 12, 2; 50-53
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
CD30-positive T-cell lymphoproliferation of the bulbar conjuntival mucosa showing spontaneous remission
Autorzy:
Paula, Marticorena Álvarez
Garrido Ceca, Guadalupe
Guijarro Rojas, Mercedes
Powiązania:
https://bibliotekanauki.pl/articles/1927972.pdf
Data publikacji:
2021
Wydawca:
Medical Education
Tematy:
CD30
T-cell
conjunctival
lymphoproliferative
Opis:
Introduction: CD30-positive T-cell lymphoproliferative lesions represent a spectrum of heterogeneous disorders. Clinical case: An incision biopsy was performed in a 25-year-old man with a lump in the bulbar conjunctiva. Immunohistochemistry indicated membrane positivity for CD3 and CD30 in over 75%. PCR identified the monoclonal nature of the T-cells. The hematological study was normal. Following biopsy, the conjunctival tumor diminished until disappear. Conclusions: Mucosal CD30-positive T-cell lymphoproliferation could be ascribed to a reactive process but it is necessary to rule out a primary conjunctival tumor or the first manifestation of an anaplastic large cell lymphoma.
Źródło:
OphthaTherapy; 2021, 8, 1; 45-48
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of suberoylanilide hydroxamic acid on peripheral blood mononuclear cell cytotoxicity towards tumor cells in canines
Autorzy:
Oyamada, T.
Okano, S.
Powiązania:
https://bibliotekanauki.pl/articles/2087212.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
antitumor effect
canines
cytotoxicity
NKG2D receptor
peripheral blood mononuclear cell
suberoylanilide hydroxamic acid
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 1; 35-41
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fever, rash, and eosinophilia - early signs of angioimmunoblastic T-cell lymphoma
Autorzy:
Wawrzycki, B.
Prystupa, A.
Szumiło, J.
Panasiuk, L.
Krasowska, D.
Powiązania:
https://bibliotekanauki.pl/articles/28762720.pdf
Data publikacji:
2021
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2021, 28, 3; 525-530
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hyperglycemia induced C2C12 myoblast cell cycle arrest and skeletal muscle atrophy by modulating sirtuins gene expression in rats
Autorzy:
Surinlert, P.
Thitiphatphuvanon, T.
Khimmaktong, W.
Pholpramool, C.
Tipbunjong, C.
Powiązania:
https://bibliotekanauki.pl/articles/2087134.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
diabetic mellitus
hyperglycemia
muscle atrophy
sirtuins
skeletal muscle
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 4; 563-572
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identification of CD4plus T cell epitopes from Staphylococcus aureus secretome using immunoinformatic prediction and molecular docking
Autorzy:
Francis, D.
Kumar, A.
Chittalakkottu, S.
Powiązania:
https://bibliotekanauki.pl/articles/2096359.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
CD4+
T cell
epitope prediction
secretory proteins
Staphylococcus aureus
peptide vaccine
molecular docking
Opis:
One major reason for the lack of clinical success of Staphylococcus aureus vaccine candidates is the inability of the antigens to develop a CD4+ T cell-mediated immune response. Hence, it is important to identify CD4+ T cell antigens from S. aureus. CD4+ T cells are activated following the presentation of epitopes derived from exogenous proteins on HLA class II molecules. Fifty-nine secretory proteins of S. aureus were analyzed computationally for the presence of HLA class II binding peptides. Fifteen-mer peptides were generated, and their binding to 26 HLA class II alleles was predicted. The structural feasibility of the peptides binding to HLA-II was studied using molecular docking. Of the 16,724 peptides generated, 6991 (41.8%) were predicted to bind to any one of the alleles with an IC50 value below 50 nM. Comparative sequence analysis revealed that only 545 of the strong binding peptides are non-self in the human system. Approximately 50% of the binding peptides were monoallele-specific. Moreover, approximately 95% of the predicted strong binding non-self peptides interacted with the binding groove of at least one HLA class II molecule with a glide score better than !10 kcal/mol. On the basis of the analysis of the strength of binding, non-self presentation in the human host, propensity to bind to a higher number of alleles, and energetically favorable interactions with HLA molecules, a set of 11 CD4+ T cell epitopes that can be used as vaccine candidates was identified.
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2021, 102, 1; 43-54
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Knowledge and Participation of Physiotherapists From the Nigerian South-west Related to the Care and Management of Individuals With Sickle Cell Disease
Autorzy:
Mbada, Chidozie E.
Binuyo, Overcomer T.
Onigbinde, Omotola A.
Ayelawa, Samuel O.
Olaniyi, Abiodun J.
Powiązania:
https://bibliotekanauki.pl/articles/2159487.pdf
Data publikacji:
2021-12-31
Wydawca:
Politechnika Opolska. Wydział Wychowania Fizycznego i Fizjoterapii
Tematy:
sickle cell disease
physiotherapy
rehabilitation
Opis:
Rehabilitative modalities such as incentive spirometry and physiotherapy interventions, e.g. aerobic exercises, have been shown to produce positive outcomes in patients with sickle cell disease (SCD). Hemispheric CVA and other complications arising from SCD are amenable to physiotherapy. There have been few studies on the effectiveness of physiotherapy in the management of individuals with SCD. The present study attempts to assess the SCD-related knowledge, attitude and level of participation of physiotherapists in the Nigerian healthcare system. It also examines a possible association between the foregoing and practice settings. The study was carried out among physiotherapists in South-West Nigeria registered on professional e-platforms. The respondents filled in an adapted electronic version of a questionnaire. The IBM SPSS 20 was used for statistical analysis, and a chi-square test was used to determine an association between the levels of knowledge, practice settings, and participation among the respondents (p < 0.05). The study findings revealed that only 19% of respondents had received a specific training related to the care of SCD patients, although 65% had been involved in the treatment of at least one patient with SCD. Only 29.5% of respondents had “Good Knowledge” of SCD pathophysiology. A statistically significant association (χ2 = 75.357, p = 0.012) was found between respondents’ level of knowledge and their practice settings, i.e. a teaching hospital mostly. The physiotherapists from the Nigerian South-West,mostly those working in teaching hospitals, reported an average level of knowledge of SCD care. Since the management of sickle cell disease is of multidisciplinary character and requires an all hands-on deck approach, controlled trials should be undertaken by physiotherapy researchers regarding the effects of modalities and interventions on pro-inflammatory bio-molecules.
Źródło:
Journal of Physical Education & Health - Social Perspective; 2021, 10, 18; 52-60
2084-7971
Pojawia się w:
Journal of Physical Education & Health - Social Perspective
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Coronaviruses fusion with the membrane and entry to the host cell
Autorzy:
Wędrowska, E.
Wandtke, T.
Senderek, T.
Piskorska, E.
Kopiński, P.
Powiązania:
https://bibliotekanauki.pl/articles/2085559.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
coronavirus
spike protein
membrane fusion
viral entry
nonstructural proteins
replication complex
Opis:
Introduction. Coronaviruses (CoVs) are positive-strand RNA viruses with the largest genome among all RNA viruses. They are able to infect many host, such as mammals or birds. Whereas CoVs were identified 1930s, they became known again in 2003 as the agents of the Severe Acute Respiratory Syndrome (SARS). The spike protein is thought to be essential in the process of CoVs entry, because it is associated with the binding to the receptor on the host cell. It is also involved in cell tropism and pathogenesis. Receptor recognition is the crucial step in the infection. CoVs are able to bind a variety of receptors, although the selection of receptor remains unclear. Coronaviruses were initially believed to enter cells by fusion with the plasma membrane. Further studies demonstrated that many of them involve endocytosis through clathrin-dependent, caveolae-dependent, clathrin-independent, as well as caveolae-independent mechanisms. Objectives. The aim of this review is to summarise current knowledge about coronaviruses, focussing especially on CoVs entry into the host cell. Advances in understanding coronaviruses replication strategy and the functioning of the replicative structures are also highlighted. The development of host-directed antiviral therapy seems to be a promising way to treat infections with SARS-CoV or other pathogenic coronaviruses. There is still much to be discovered in the inventory of pro-and anti-viral host factors relevant for CoVs replication. The latest pandemic danger, originating from China, has given our previously prepared work even more of topicality.
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 2; 175-183
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of administering activated lymphocytes originated from the dam on the immune cell reaction in Holstein calves
Autorzy:
Ohtsuka, H.
Yamaguchi, T.
Maeda, Y.
Tomioka, M.
Tajima, M.
Powiązania:
https://bibliotekanauki.pl/articles/2087343.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
bovine herpesvirus
calves
dam
immune cells
lymphokine activated killer
Źródło:
Polish Journal of Veterinary Sciences; 2020, 23, 1; 109-117
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of aqueous extract from Scutellaria baicalensis Georgi roots on CD4+ and CD8+ T cell responses during experimental infection with Trichinella spiralis in mice
Autorzy:
Piekarska, J.
Szczypka, M.
Gorczykowski, M.
Króliczewska, B.
Miśta, D.
Oszmiański, J.
Powiązania:
https://bibliotekanauki.pl/articles/2087259.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Scutellaria baicalensis
Trichinella spiralis
immunomodulation
Źródło:
Polish Journal of Veterinary Sciences; 2020, 23, 4; 501-510
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Low-active high-density Noctiluca scintillans cells in surface seawater
Autorzy:
Tada, K.
Asahi, T.
Kitatsuji, S.
Nomura, M.
Yamaguchi, H.
Ichimi, K.
Powiązania:
https://bibliotekanauki.pl/articles/2079194.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Instytut Oceanologii PAN
Tematy:
Noctiluca scintillans
cell
dinoflagellate
mesozooplankton
adenosine triphosphate
sea surface
surface water
activity
Opis:
Noctiluca scintillans is an important member of the mesozooplankton in terms of biomass and production in the Seto Inland Sea, Japan. The densities and adenosine triphosphate (ATP) contents of N. scintillans cells were measured. Vertical profiles of N. scintillans cellular activity in the coastal water were determined and the ATP contents were high at middle layers, with a maximum depth of 10 m. ATP contents were low in the surface and lower layers. These results suggest that active N. scintillans cells in subsurface layers with low density play an important role in the coastal ecosystem, and high-density cells in the surface water are not active.
Źródło:
Oceanologia; 2020, 62, 3; 402-407
0078-3234
Pojawia się w:
Oceanologia
Dostawca treści:
Biblioteka Nauki
Artykuł

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