- Tytuł:
- Synchronous occurrence of multiple focal nodular hyperplasia and huge hepatic Perivascular epithelioid cells tumor (PEComa) in young woman after oral contraceptive use – is there a common pathogenesis?
- Autorzy:
-
Durczyński, Adam
Hogendorf, Piotr
Szymański, Dariusz
Sporny, Stanisław
Strzelczyk, Janusz - Powiązania:
- https://bibliotekanauki.pl/articles/1396820.pdf
- Data publikacji:
- 2012-10-01
- Wydawca:
- Index Copernicus International
- Tematy:
-
liver
perivascular epithelioid cells tumor
focal nodular hyperplasia
oral contraceptive - Opis:
- The association of focal nodular hyperplasia (FNH) and various neoplasms was described, but coincidence of multiple FNH and hepatic perivascular epithelioid cells tumor (PEComa) has not been reported. The clinical debate of oral contraceptive (OC) influence on FNH growth is ongoing, but no evidence exists about association of hepatic PEComa with OC use. Herein, we report a case of two FNH lesions and huge (150x100x80 mm) left hepatic lobe PEComa that occurred simultaneously in 18-year-old female with previous two year history of OC use, who underwent left hemihepatectomy and right hepatic FNH enucleation. Up to date, the patient has been followed-up for 65 months and remained disease-free. FNH and PEComa have a common vascular cytogenetic denominator. Our case raising a question of a causal relationship of FNH and PEComa with OC use that might be attributed to vascular changes. Future researches of larger sample sizes should further address this issue.
- Źródło:
-
Polish Journal of Surgery; 2012, 84, 9; 457-460
0032-373X
2299-2847 - Pojawia się w:
- Polish Journal of Surgery
- Dostawca treści:
- Biblioteka Nauki
Artykuł