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Wyszukujesz frazę "Plata, Joanna" wg kryterium: Wszystkie pola

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    Wyświetlanie 1-7 z 7
    Tytuł:
    Irlandia kobiet. Początki irlandzkiego ruchu kobiecego.
    Ireland of women. The origins of the Irish women’s movement.
    Autorzy:
    Plata, Joanna
    Powiązania:
    https://bibliotekanauki.pl/articles/528368.pdf
    Data publikacji:
    2015
    Wydawca:
    Krakowska Akademia im. Andrzeja Frycza Modrzewskiego
    Tematy:
    Ireland
    feminism
    herstory
    Ladies’ Land League
    Daughters of Erin
    Irish Women Workers’ Union
    Opis:
    The aim of this article is to familiarize the Polish readers the most important events in the history of the beginnings of feminism in Ireland. The autor assumes that history, making heroes of events only male political, military and religious leaders, is one of those scientific discipline that significantly ignore the achievements of women. She focuses on herstory of Irish women – the first social activists, politicians, feminists and nationalists, at the same time retains the important historical context of their activity. Using the English-language literature dedicated to research of the history of Irish women, enriches Polish publications of authors rarely invoked or absent in Polish literature. The text contains information about the first Irish women’ organizations from the late nineteenth and early twentieth century, such as Ladies’ Land League, Daughters of Erin and Irish Women Workers’ Union. An important context of their activity is the evolution of the Irish independence movement, which was formed by many women too. As the author assumed, the article may provide a basis for further discussion of the history of the Irish women’s movement and its current status. Among quoted authors are such well-known researchers of Irish history, as Maria Luddy and Margaret Mac Curtain.
    Źródło:
    Państwo i Społeczeństwo; 2015, 1; 227-241
    1643-8299
    2451-0858
    Pojawia się w:
    Państwo i Społeczeństwo
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Immune response against HtrA proteases in children with cutaneous mastocytosis
    Autorzy:
    Renke, Joanna
    Kędzierska-Mieszkowska, Sabina
    Lange, Magdalena
    Nedoszytko, Bogusław
    Liberek, Anna
    Plata-Nazar, Katarzyna
    Renke, Marcin
    Wenta, Tomasz
    Żurawa-Janicka, Dorota
    Skórko-Glonek, Joanna
    Lipińska, Barbara
    Powiązania:
    https://bibliotekanauki.pl/articles/1038382.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    HtrA proteases
    children
    cutaneous mastocytosis
    mast cells
    Opis:
    Mast cells play an important role in both, the innate and adaptive immunity, however, clonal proliferation of abnormal mast cells in various organs leads to mastocytosis. A skin variant of the disease, cutaneous mastocytosis (CM) is the most frequent form of mastocytosis in children. HtrA proteases are modulators of important cellular processes, including cell signaling and apoptosis, and are related to development of several pathologies. The above and the observation that mast cells constitutively release the HtrA1 protein, prompted us to investigate a possible involvement of the HtrA proteins in pediatric CM. Levels of the serum autoantibodies (IgG) against the recombinant HtrA proteins (HtrA1-4) in children with CM (n=36) and in healthy controls (n=62) were assayed. Anti-HtrA IgGs were detected using enzyme linked immunosorbent assay (ELISA) and Western-blotting. In the CM sera, levels of the anti-HtrA1 and anti-HtrA3 autoantibodies were significantly increased when compared to the control group, while the HtrA protein levels were comparable. No significant differences in the anti-HtrA2 IgG level were found; for the anti-HtrA4 IgGs lower levels in CM group were revealed. In healthy children, the IgG levels against the HtrA1, -3 and -4 increased significantly with the age of children; no significant changes were observed for the anti-HtrA2 IgG. Our results suggest involvement of the HtrA1 and HtrA3 proteins in pediatric CM; involvement of the HtrA4 protein is possible but needs to be investigated further. In healthy children, the autoantibody levels against HtrA1, -3 and -4, but not against HtrA2, increase with age.
    Źródło:
    Acta Biochimica Polonica; 2018, 65, 3; 471-478
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Graves disease, celiac disease and liver function abnormalities in a patient - clinical manifestation and diagnostic difficulties
    Autorzy:
    Góra-Gębka, Magdalena
    Woźniak, Małgorzata
    Cielecka-Kuszyk, Joanna
    Korpal-Szczyrska, Maria
    Sznurkowska, Katarzyna
    Zagierski, Maciej
    Jankowska, Irena
    Plata-Nazar, Katarzyna
    Kamińska, Barbara
    Liberek, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/1039288.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    autoimmune disease
    Graves' disease
    celiac disease
    liver abnormalities
    children
    Opis:
    Autoimmune diseases due to probable common pathogenesis tend to coexist in some patients. Complex clinical presentation with diverse timing of particular symptoms and sophisticated treatment with numerous side effects, may cause diagnostic difficulties, especially in children. The paper presents diagnostic difficulties and pitfalls in a child with Graves' disease, celiac disease and liver function abnormalities.
    Źródło:
    Acta Biochimica Polonica; 2014, 61, 2; 281-284
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Clinical parameters of inflammatory bowel disease in children do not correlate with four common polymorphisms of the transforming growth factor β1 gene
    Autorzy:
    Liberek, Anna
    Jakóbkiewicz-Banecka, Joanna
    Kloska, Anna
    Świderska, Joanna
    Kmieć, Zbigniew
    Łuczak, Grażyna
    Wierzbicki, Piotr
    Liberek, Tomasz
    Marek, Krzysztof
    Plata-Nazar, Katarzyna
    Sikorska-Wiśniewska, Grażyna
    Kamińska, Barbara
    Węgrzyn, Grzegorz
    Powiązania:
    https://bibliotekanauki.pl/articles/1039871.pdf
    Data publikacji:
    2011
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    pediatric patients
    gene polymorphism
    Transforming growth factor β1
    inflammatory bowel disease
    Opis:
    Transforming growth factor β1 (TGF-β1) is a cytokine affecting cell proliferation and development, which also has an immunomodulatory activity. Correlations between polymorphisms of the TGF-β1 gene and clinical parameters of inflammatory bowel disease (IBD) were reported previously in adults. Here, we tested whether such correlations occur in pediatric patients suffering from IBD. One hundred and four pediatric IBD patients were involved in this study. Among them, 36 were diagnosed with Crohn's Disease (CD) and 68 were diagnosed with ulcerative colitis (UC). The control group consisted of 103 children, in which IBD was excluded. TGF-β1 levels were determined in plasma and intestinal mucosa samples. The presence of the TGF β1 protein and the amount of TGF β1 mRNA were estimated in intestinal mucosa by immunohistochemistry and reverse transcription Real-Time PCR, respectively. Four common polymorphisms of the TGF-β1 gene were investigated: -800G/A, -509C/T, 869T/C and 915G/C. No significant correlation between TGF-β1 genotypes and (i) TGF-β1 levels in plasma and tissue samples, (ii) TGF-β1 gene expression efficiency in intestinal mucosa, (iii) IBD clinical parameters and (iv) inflammatory activity could be detected in children suffering from IBD. We conclude that, contrary to previous suggestions, the four common polymorphisms of the TGF-β1 gene do not influence the susceptibility to or clinical parameters of IBD in the tested population of children.
    Źródło:
    Acta Biochimica Polonica; 2011, 58, 4; 641-644
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Association between uridin diphosphate glucuronosylotransferase 1A1 (UGT1A1) gene polymorphism and neonatal hyperbilirubinemia
    Autorzy:
    Mazur-Kominek, Katarzyna
    Romanowski, Tomasz
    Bielawski, Krzysztof
    Kiełbratowska, Bogumiła
    Preis, Krzysztof
    Domżalska-Popadiuk, Iwona
    Słomińska-Frączek, Magdalena
    Sznurkowska, Katarzyna
    Renke, Joanna
    Plata-Nazar, Katarzyna
    Śledzińska, Karolina
    Sikorska-Wiśniewska, Grażyna
    Góra-Gębka, Magdalena
    Liberek, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/1038662.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    UGT1A1 gene
    polymorphism
    hyperbilirubinemia
    neonates
    Opis:
    Objective: To assess the prevalence of UGT1A1*28 and UGT1A1*60 polymorphisms of UGT1A1 gene and their association with hyperbilirubinemia. Study design: The study was performed at a single centre - at the Department of Obstetrics of the Medical University of Gdansk in Poland. DNA was isolated from Guthrie cards of 171 infants. Only full term newborns (gestational age 38-42 weeks) were included in the study. Fluorescent molecular probes were used for UGT1A1 promoter variation analysis. The presence of UGT1A1*28 polymorphism was detected with a dual-probe system, and UGT1A1*60 with a SimpleProbe™. Result: Homozygous UGT1A1*28 and UGT1A1*60 genotypes were detected in 14.6% and 20.5% of the newborns, respectively. Homozygous (G/G) genotypes of UGT1A1*60 polymorphism were found in all of the UGT1A1*28 (i.e. (TA)7/(TA)7) homozygotes. More than 80% (55/66) of the children with "wild" type UGT1A1*28 genotype (where no polymorphism was detected) (i.e. (TA)6/(TA)6) carried the "wild" (T/T) genotype of UGT1A1*60 as well. The UGT1A1*28 polymorphism was detected more often among neonates with elevated bilirubin. Hyperbilirubinemia was diagnosed more frequently in boys. Conclusion: Polymorphisms of the UGT1A1 gene frequently co-exist in neonates. The presence of UGT1A1*28 polymorphism and male gender seem to predispose to neonatal hyperbilirubinemia.
    Źródło:
    Acta Biochimica Polonica; 2017, 64, 2; 351-356
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Transforming growth factor β1 protein and mRNA levels in inflammatory bowel diseases: towards solving the contradictions by longitudinal assessment of the protein and mRNA amounts
    Autorzy:
    Liberek, Anna
    Kmieć, Zbigniew
    Wierzbicki, Piotr
    Jakóbkiewicz-Banecka, Joanna
    Liberek, Tomasz
    Łuczak, Grażyna
    Plata-Nazar, Katarzyna
    Słomińska-Frączek, Magdalena
    Kaszubowska, Lucyna
    Gabig-Cimińska, Magdalena
    Węgrzyn, Alicja
    Powiązania:
    https://bibliotekanauki.pl/articles/1039466.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Crohn's disease
    ulcerative colitis
    Transforming Growth Factor-β1
    longitudinal assessment of TGF-β1 level
    Opis:
    Previously published studies on levels of the transforming growth factor-β1 (TGF-β1) protein and mRNA of the corresponding gene in patients suffering from inflammatory bowel diseases (IBD) gave varying results, leading to contradictory conclusions. To solve the contradictions, we aimed to assess longitudinally TGF-β1 protein and mRNA levels at different stages of the disease in children suffering from IBD. The study group consisted of 19 pediatric patients with IBD at the age between 3.5 and 18.4 years. The control group consisted of 42 children aged between 2.0 and 18.0 years. The plasma TGF-β1 concentration was measured with ELISA. mRNA levels of the TGF-β1 gene isolated from samples of the intestinal tissue were assessed by reverse transcription and real-time PCR. Levels of TGF-β1 protein in plasma and corresponding mRNA in intestinal tissue were significantly higher in IBD patients than in controls. TGF-β1 and corresponding transcripts were also more abundant in plasma and intestinal tissue, respectively, in patients at the active stage of the disease than during remission. In every single IBD patient, plasma TGF-β1 level and mRNA level in intestinal tissue was higher at the active stage of the disease than during remission. Levels of TGF-β1 and corresponding mRNA are elevated during the active stage of IBD but not during the remission. Longitudinal assessment of this cytokine in a single patient may help to monitor the clinical course of IBD.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 4; 683-688
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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