Wszystkie pola: Liberek, T. - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Ocena przydatności testu ACB w określaniu lokalizacji zakażenia układu moczowego
Ocenka prigodnosti testa ACB v opredelenii lokalizirovanija infekcii mochevojj sistemy
Estimation of ACB test usefulness in determining of localization of urinary system infection
Autorzy:: Lichodziejewska, M.
Liberek, T.
Galiński, J.
Manitius, A.
Powiązania:: https://bibliotekanauki.pl/articles/2187421.pdf
Data publikacji:: 1988
Wydawca:: Polskie Towarzystwo Diagnostyki Laboratoryjnej
Tematy:: choroby czlowieka
choroby ukladu moczowego
objawy kliniczne
lokalizacja zakazenia
choroby dolnych drog moczowych
choroby gornych drog moczowych
test ACB
wartosc diagnostyczna
Źródło:: Diagnostyka Laboratoryjna; 1988, 24, 5; 241-247
0867-4043
Pojawia się w:: Diagnostyka Laboratoryjna
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Peripheral regulatory T cells and anti-inflammatory cytokines in children with juvenile idiopathic arthritis
Autorzy:: Sznurkowska, Katarzyna
Boćkowska, Małgorzata
Zieliński, Maciej
Plata-Nazar, Katarzyna
Trzonkowski, Piotr
Liberek, Anna
Kamińska, Barbara
Szlagatys-Sidorkiewicz, Agnieszka
Powiązania:: https://bibliotekanauki.pl/articles/1038532.pdf
Data publikacji:: 2018
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: Tregs
IL-10
TGF-β1
juvenile idiopathic arthritis
Opis:: Background: Juvenile idiopathic arthritis (JIA) is a chronic, heterogenous inflammatory disease of unclear pathogenesis. JIA is hypothesized to be linked to a defective immune regulation. Anti-inflammatory cytokines belong to the best known regulatory factors. T-regulatory cells are a crucial cellular component of immune tolerance. One of their functions is synthesis of interleukin 10 (IL-10) and transforming growth factor beta1 (TGF-β1). The aim of this study was to determine the proportion of T-regulatory cells (CD4+CD25highFOXP3+) in peripheral blood, and serum levels of TGF-β1 and IL-10 in patients with JIA. Methods: The study included 25 patients with newly diagnosed JIA: oligoarthritis (n=17) and polyarthritis (n=8). The control group was comprised of 17 healthy children. CD4+CD25highFOXP3+ T cells in peripheral blood were quantified by means of three-color flow cytometry. Serum concentrations of TGF-β1 and IL-10 were estimated with ELISA. Results: The proportion of peripheral CD4+CD25highFOXP3+ cells in patients with JIA was significantly higher than in the controls (p=0.04). The two groups did not differ significantly in terms of their TGF-β1 and IL-10 concentrations. Conclusions: At the time of diagnosis, children with JIA presented with an elevated proportion of T-regulatory cells (CD4+CD25highFOXP3+) in peripheral blood. Anti-inflammatory cytokines, IL-10 and TGF-β1, are not upregulated in the serum of patients with JIA, and therefore should not be considered as biomarkers of this condition.
Źródło:: Acta Biochimica Polonica; 2018, 65, 1; 119-123
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Helicobacter pylori increases expression of proapoptotic markers Fas and FasL on CD4 lymphocytes in children
Autorzy:: Kotłowska-Kmieć, Aldona
Bąkowska, Alicja
Szarszewski, Adam
Kamińska, Barbara
Łuczak, Grażyna
Radys, Wojciech
Landowski, Piotr
Brodzicki, Jacek
Korzon, Maria
Liberek, Anna
Powiązania:: https://bibliotekanauki.pl/articles/1040535.pdf
Data publikacji:: 2009
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: T cell
H. pylori
FasL
Fas
apoptosis
lymphocyte
Opis:: The pathomechanism of Helicobacter pylori action upon gastric mucosa and its role in the pathogenesis of gastritis have not been fully elucidated. The aim of this study was to evaluate the most prevalent lymphocyte subpopulations of the gastric mucosa in gastritis in children, as well as to evaluate the expression of Fas and Fas ligand receptors (FasL), periapoptotic markers of gastric mucosa lymphocytes before and after H. pylori eradication. Forty nine patients aged 6 to 17 years, investigated due to chronic abdominal pain, were studied. The obtained tissue samples were analysed by immunohistochemistry. Different lymphocyte subsets were quantified on the basis of surface antigen expression (CD3, CD4, CD8, CD20), secreted cytokines (IL-4, IL-6, IFNγ) and Fas and FasL proteins in the gastric mucosa. B and T helper lymphocytes were found to play a major role in the inflammatory infiltration in the gastric mucosa in children during H. pylori infection. Their expression was found to decrease after eradication. The enhanced expression of Fas receptor on lymphocytes before treatment and a decrease of this expression after eradication of H. pylori were shown. It was demonstrated that there is a correlation between CD4 and Fas receptor expression that may induce apoptosis of the helper lymphocytes in infected children.
Źródło:: Acta Biochimica Polonica; 2009, 56, 3; 433-438
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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