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    Wyświetlanie 1-7 z 7
    Tytuł:
    Acute cholecystitis in patients with diabetes mellitus - systematic review
    Autorzy:
    Łącka, Monika
    Spychalski, Piotr
    Dobrzycka, Małgorzata
    Rostkowska, Olga
    Kobiela, Jarosław
    Powiązania:
    https://bibliotekanauki.pl/articles/895729.pdf
    Data publikacji:
    2020-01-09
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    complications
    Diabetes Mellitus
    Cholecystitis
    course of hospitalization
    Opis:
    Introduction: According to the WHO, an estimated 422 million people are suffering from diabetes worldwide. Among them, the incidence of cholelithiasis is higher than in the healthy population. The aim of this literature review was to summarize the available evidence about acute cholecystitis in patients with diabetes. Materials and methods: This study adhered to the PRISMA guidelines. The course of hospitalization of patients with and without diabetes who underwent cholecystectomy due to acute cholecystitis was compared. Following information was abstracted from original studies: general study information, patient characteristics, complications, and recommendations for patients with diabetes. Results: Initial search provided 1632 results. After full text assessment, 40 studies met the inclusions criteria. Operative and postoperative complication rates were significantly higher among the diabetic patients. Diabetes is a risk factor for conversion from laparoscopic to open cholecystectomy method. The authors' opinions on elective surgery before the onset of acute cholecystitis symptoms are divided. Conclusions: Diabetic patients are at greater risk of developing complications. An individualized screening and treatment approach, as well as proper preparation of the diabetic patient for an elective cholecystectomy could have a positive effect on the outcome. However, the low quality of the data from the systematic review does not allow for meta-analysis, which is why we cannot draw strong conclusions.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2019, 2, 2; 71-79
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Changes in expression of serine proteases HtrA1 and HtrA2 during estrogen-induced oxidative stress and nephrocarcinogenesis in male Syrian hamster
    Autorzy:
    Zurawa-Janicka, Dorota
    Kobiela, Jaroslaw
    Stefaniak, Tomasz
    Wozniak, Agnieszka
    Narkiewicz, Joanna
    Wozniak, Michał
    Limon, Janusz
    Lipinska, Barbara
    Powiązania:
    https://bibliotekanauki.pl/articles/1040768.pdf
    Data publikacji:
    2008
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    17-β-estradiol
    HtrA proteases
    estrogen-induced carcinogenesis
    oxidative stress
    Opis:
    Serine proteases HtrA1 and HtrA2 are involved in cellular stress response and development of several diseases, including cancer. Our aim was to examine the involvement of the HtrA proteins in acute oxidative stress response induced in hamster kidney by estrogen treatment, and in nephrocarcinogenesis caused by prolonged estrogenization of male Syrian hamster. We used semi-quantitative RT-PCR to estimate the HtrA1 and HtrA2 mRNA levels in kidney tissues, and Western blotting to monitor the amount of the HtrA proteins. Within the first five hours following estrogen administration both HtrA1 mRNA and the protein levels were increased significantly. No changes in the expression of HtrA2 were observed. This indicates that HtrA1 may be involved in the response against oxidative stress induced by estrogen treatment in hamster kidney. During prolonged estrogenization, a significant reduction of the HtrA1 mRNA and protein levels was observed after 6 months of estradiol treatment, while the expression of HtrA2 was significantly elevated starting from the third month. This suggests an involvement of the HtrA proteins in estrogen-induced nephrocarcinogenesis in hamster. Using fluorescence in situ hybridization we localized the HtrA1 gene at the qb3-4 region of Syrian hamster chromosome 2, the region known to undergo a nonrandom deletion upon prolonged estrogenization. It is possible that the reduced level of HtrA1 expression is due to this chromosomal aberration. A full-length cDNA sequence of the hamster HtrA1 gene was obtained. It codes for a 50 kDa protein which has 98 and 96% identity with mouse and human counterparts, respectively.
    Źródło:
    Acta Biochimica Polonica; 2008, 55, 1; 9-20
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Costs of elective vs emergency cholecystectomy in diabetic patients
    Autorzy:
    Łącka, Monika
    Spychalski, Piotr
    Obłój, Paweł
    Łaski, Dariusz
    Rostkowska, Olga
    Wieszczy, Paulina
    Kobiela, Jarosław
    Powiązania:
    https://bibliotekanauki.pl/articles/1196132.pdf
    Data publikacji:
    2020-12-03
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    diabetes
    elective cholecystectomy
    emergency cholecystectomy
    costs of hospitalization
    Opis:
    Introduction: Hospitalization costs of diabetic patients are estimated to be higher than non-diabetic. Literature on the topic is however limited. The aim of this study was to compare the costs of elective and emergency cholecystectomy of diabetic and non-diabetic patients. Material and methods: A retrospective analysis involved diabetic versus non-diabetic age- and sex-matched patients who underwent emergency and elective cholecystectomy at a single center in Poland between 2016-2019. Results: The total costs of an elective cholecystectomy were 739.31 ± 423.07 USD for diabetic patients and 797.14 ± 772.24 USD for non-diabetic patients (p = 0.51). Whereas emergency cholecystectomy total costs were 3950.72 ± 2856.83 USD (diabetic patients) and 2464.31 ± 1718.21 USD (non-diabetic patients) (p = 0.04). The difference in total costs between elective cholecystectomy vs emergency cholecystectomy in both groups (diabetic vs non-diabetic patients) was statistically significant (p < 0.01 vs p < 0.05 respectively). Conclusions: In this study we demonstrated that emergency cholecystectomy is associated with a significant increase in hospitalization costs, particularly in diabetic patients. This suggests that early qualification of diabetic patients for an elective cholecystectomy could be beneficial for both diabetic patients and public health insurers.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2020, 3, 2; 37-43
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Interdisciplinary treatment of large adrenocortical carcinoma infiltrating inferior vena cava
    Autorzy:
    Dobrzycka, Małgorzata
    Spychalski, Piotr
    Rusek, Urszula
    Brzeziński, Michał
    Kobiela, Jarosław
    Kłosowski, Przemysław
    Berendt-Obołończyk, Monika
    Łachiński, Andrzej
    Sworczak, Krzysztof
    Śledziński, Zbigniew
    Powiązania:
    https://bibliotekanauki.pl/articles/895737.pdf
    Data publikacji:
    2020-01-09
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    surgical treatment
    adrenocortical carcinoma
    adrenal cancer
    Opis:
    Adrenal tumors are common neoplasms and majority of them are small, benign, hormonally inactive adrenocortical adenomas. Whereas adrenal cancer (ACC) is a rarely occurring (5% of adrenal tumors) but highly aggressive neoplasm. The early diagnosis and complete surgical resection is the only effective treatment option. Laparoscopic adrenalectomy is the gold standard for small and medium tumors. Whereas for large tumors classic adrenalectomy is considered a procedure of choice with a proven better oncological outcome. We herein report a case of a 57-year-old female diagnosed with a large, advanced left adrenal tumor with invasion of vena cava. It was diagnosed in CT and proven in core biopsy. Open adrenalectomy with thoracotomy was conducted to completely resect the tumor by an interdisciplinary team.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2019, 2, 2; 38-42
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Introduction of new technique of single-port transgastric access for repeated debridement of infected pancreatic necrosis
    Autorzy:
    Kobiela, Jarosław
    Hać, Stanisław
    Śledziński, Zbigniew
    Powiązania:
    https://bibliotekanauki.pl/articles/1396146.pdf
    Data publikacji:
    2013-04-01
    Wydawca:
    Index Copernicus International
    Tematy:
    acute pancreatitis
    walled-off pancreatic necrosis
    minimally invasive debridement
    single port surgery
    Opis:
    In this article we introduce a novel technique of repeated single-port transgastric debritment of walledoff pancreatic necrosis using TriPort ™ Access System. The presented technique seems an appealing and innovative approach to the treatment of walled-off pancreatic necrosis in acute pancreatitis patients. Studies proving feasibility, safety and efficiency are necessary to elucidate real value of the technique
    Źródło:
    Polish Journal of Surgery; 2013, 85, 4; 228-233
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Obesity in work-up of kidney transplant candidates – review of clinical practice guidelines
    Autorzy:
    Dobrzycka, Małgorzata
    Spychalski, Piotr
    Łącka, Monika
    Proczko-Stepaniak, Monika
    Dębska-Ślizień, Alicja
    Kaska, Łukasz
    Kobiela, Jarosław
    Powiązania:
    https://bibliotekanauki.pl/articles/1196784.pdf
    Data publikacji:
    2020-11-16
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    obesity
    end-stage kidney disease
    bariatric surgery
    Opis:
    Background: Incidence of morbid obesity is rising worldwide. Current clinical practice guidelines for the pre-transplant evaluation of end-stage kidney disease (ESKD) patients lack clear recommendations on morbid obesity. Material and methods: The aim of this review was to summarize the current guidelines on the role and treatment of obesity in kidney transplant recipients. Eight current national and international clinical practice guidelines were identified in a comprehensive literature search. Results: All guidelines underline early detection of obesity and obesity-related comorbidities in ESKD patients. Only two guidelines explored the role of weight-loss surgery, however due to the lack of sufficient evidence no formal recommendation of surgical procedure was given. Conclusions: Diagnosis and treatment of obesity remains underappreciated in the current guidelines, most of which do not include pharmacological and surgical interventions. High-quality evidence is warranted to assess the role of weight-loss including surgery in ESKD patients and to update the recommendations in future guidelines.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2020, 3, 2; 72-79
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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