- Tytuł:
- Application of Taguchi method in the optimization of synthesis of cellulose-MgO bionanocomposite as antibacterial agent
- Autorzy:
-
Safaei, Mohsen
Taran, Mojtaba
Imani, Mohammad Moslem
Moradpoor, Hedaiat
Rezaei, Farzad
Jamshidy, Ladan
Rezaei, Razieh - Powiązania:
- https://bibliotekanauki.pl/articles/778461.pdf
- Data publikacji:
- 2019
- Wydawca:
- Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
- Tematy:
-
cellulose biopolymer
magnesium oxide nanoparticles
nanocomposite
antibacterial activity
Taguchi method - Opis:
- In this study, optimal conditions to form cellulose-MgO nanocomposite with antibacterial properties were evaluated. Applying the Taguchi method, 9 experiments were designed and the effects of different concentrations of biopolymers cellulose (0.5, 1 and 2 mg/ml), MgO nanoparticles (2, 4 and 8 mg/ml) and stirring times (30, 60 and 90 min) on antibacterial activity of synthesized nanocomposites were assessed. The characterizations of products were investigated by dynamic light scattering (DLS), raman spectroscopy, scanning electron microscope (SEM), thermogravimetric analysis (TGA) and differential thermal analysis (DTA). The results showed that the nano-composite produced in the conditions of experiment 9 (MgO 8 mg/ml, cellulose 2 mg/ml and stirring time of 60 min) has the strongest antibacterial activity. The outcomes of both methods of colony forming units (CFU) and disc diffusion indicated that the antibacterial activity of cellulose-MgO nanocomposite was significantly higher than its components (P <0.05). Thermal analysis indicated improvement in the thermal stability of the cellulose biopolymer after the formation of the nanocomposite. Due to the improvement of the antibacterial properties of cellulose-MgO nanocomposite compared to its components, we can use it as a new antibacterial agent in the fields of pharmaceutical, medicine and dentistry.
- Źródło:
-
Polish Journal of Chemical Technology; 2019, 21, 4; 116-122
1509-8117
1899-4741 - Pojawia się w:
- Polish Journal of Chemical Technology
- Dostawca treści:
- Biblioteka Nauki
Artykuł