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Tytuł:
Il perturbante come strategia sovversiva: realismo magico ed elementi fantastici nei Racconti sardi di Grazia Deledda
The Uncanny as a Subversive Strategy: Magic Realism and Fantastic Elements in Grazia Deledda’s Racconti sardi
Autorzy:
Gorgojo-Iglesias, Raisa
Powiązania:
https://bibliotekanauki.pl/articles/34670925.pdf
Data publikacji:
2024-06-30
Wydawca:
Wydawnictwo Adam Marszałek
Tematy:
Grazia Deledda
magic realism
fantastic literature
literary foremothers
feminist literary criticism
realismo magico
letteratura fantastica
antenate letterarie
critica letteraria femminista
Opis:
This paper discusses the absence of Grazia Deledda both in Spanish university curricula and on the Spanish publishing market, an oblivion shared by other female authors of her time. This exclusion has a dual cause: the writers’ gender and the literary genre they cultivated. In this study, I offer a new reading of Deledda’s Racconti sardi (1894) through a critical analysis of its architectural elements, resonating with magic realism and the fantastic genre. These elements fit within the aesthetics of the liminal (Tomassini, 1992), which seeks to reinterpret the history of otherness as opposed to normative and legitimised histories. While magic realism proposes a world tailored to the experience of the other, which belies the official truth, the fantastic highlights the flaws of the uniform conception of reality. Such narratives may convey a subversive, albeit often overlooked, message as the mechanisms of the genres of the non-real promote readers’ estrangement, a revision of the contract of fiction and, therefore, multiple levels of reading. These accomplishments make Deledda a classic author whose narrative production, which starts from the local to become universal, is worth continual re-reading.
Questo studio nasce dalla constatazione dell’assenza di Grazia Deledda sia dai curricula delle università spagnole sia dal mercato editoriale della Spagna. Tale oblio è stato subìto da altre autrici di varie nazionalità a lei contemporanee e ha una doppia origine: il loro genere e il genere letterario che esplorano. La produzione di studi accademici che analizzano l’opera di Grazia Deledda contribuirà al suo concreto inserimento in specifiche sezioni del programma di studi, oltre a fornire una base per la promozione e la diffusione della sua opera sul piano editoriale. Con questo obiettivo, il presente studio si propone di offrire una nuova lettura dei Racconti sardi (1894) di Grazia Deledda attraverso un’analisi critica della sua architettura, tra realismo magico e genere fantastico, all’interno di quella che potrebbe anche essere definita l’estetica del limite (Tomassini, 1992). Il fantastico o perturbante e il realismo magico tentano di rielaborare la storia dell’alterità in contrapposizione alle storie normative e legittimate, proponendo un mondo a misura dell’esperienza dell’altro che rifiuta la verità ufficiale, nel caso del realismo magico, o sottolineando i difetti della concezione univoca della realtà, nel caso del fantastico. Si tratta di narrazioni che, in un secondo livello di lettura, possono presentare un potenziale messaggio sovversivo che passa inosservato grazie ai meccanismi dei generi del non reale, meccanismi che permettono un allontanamento del lettore, una riformulazione del patto di finzione e, quindi, molteplici livelli di lettura che, in sostanza, fanno di Deledda un’autrice classica, meritevole di continue riletture, la cui narrazione parte dal locale per diventare universale.
Źródło:
Italica Wratislaviensia; 2024, 15.1; 85-104
2084-4514
Pojawia się w:
Italica Wratislaviensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Giuliana Strambi, Le terre agricole abbandonate. Il recupero produttivo nella legislazione sulle “banche della terra” e nel Testo unico in materia di foreste e filiere forestali, Editoriale Scientifica, Napoli 2022
Autorzy:
Budzinowski, Roman
Powiązania:
https://bibliotekanauki.pl/articles/29982020.pdf
Data publikacji:
2023
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Źródło:
Przegląd Prawa Rolnego; 2023, 1(32); 205-207
1897-7626
2719-7026
Pojawia się w:
Przegląd Prawa Rolnego
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Il panegiristico ‘arco trionfale’ di Jan Zamoyski quale immagine speculare del modello classico del ‘vir bonus’
Panegyrical “arco trionfale” of Jan Zamoyski as an Artistic Mirror of a Classical Model of “vir bonus”
Autorzy:
Kucharczyk, Olga
Powiązania:
https://bibliotekanauki.pl/articles/37503642.pdf
Data publikacji:
2023
Wydawca:
Akademia Ignatianum w Krakowie
Tematy:
Zamoyski Jan
panegyrical iconography
civic and political virtue
moralistic allegory
citizen
moralism
antiquity
philosophy
Opis:
L’“Arco trionfale” inciso da Giacomo Lauro intorno al 1601–1603 è forse l’incisione dell’epoca più distinguibile associata a Jan Zamoyski (1542–1605), che presenta un’immagine del Cancelliere e Gran Etmano della Corona. Riferimenti all’incisione sono apparsi in quasi tutti gli studi dedicati all’arte moderna polacca, nei testi sul mecenatismo artistico del grande Cancelliere e negli studi sull’arte nei contesti della politica, della propaganda e della glorificazione. Nella maggior parte dei casi, un’analisi del concetto è stata superficiale, benché la lastra di rame presenti profondi contenuti, fino ad oggi tuttavia rimasti ignorati. Il suo programma iconografico estremamente erudito dovrebbe essere interpretato attraverso il prisma della cultura antica e della filosofia morale del ciceronismo, dell’aristotelismo o dell’interpretazione didattica e morale di Platone ed Isocrate. Nell’incisione possiamo trovare numerosi motivi che si riferiscono all’educazione morale civica basata sulla regola della virtù stoica, la necessità di esercitarsi nel servizio e nella difesa della patria, la dottrina della “guerra giusta” così come l’antico topos del pax et bellum. Sono inoltre evidenti nell’immagine gli elementi dell’etica, della scienza dello stato e della tradizione polacca della teoria giuridica. L’arco trionfale di Jan Zamoyski costituisce uno specchio parenetico della sua vita e delle sue virtù come “Cittadino esemplare” ed “ideale servo della stato”, semplicemente vir bonus.
“Arco trionfale” engraved by Giacomo Lauro in circa 1601–1603 is perhaps the most distinguishable period print associated with Jan Zamoyski (1542–1605), presenting an image of the Chancellor and Grand Hetman of the Crown. References to the print appeared in almost all studies dedicated to Polish modern art, in texts on the great Chancellor’s artistic patronage and in studies on art in the contexts of politics, propaganda and glorification. More often than not, an analysis of the concept was superficial, although the copperplate presents profound, though hitherto unrecognised content. Its highly erudite iconographic programme ought to be interpreted through the prism of ancient culture and the moral philosophy of Ciceronianism, Aristotelianism or the didactic and moral interpretation of Plato and Isocrates. We find in the print numerous motifs referring to moral civic education based on the rule of Stoic virtue, the need to exercise oneself in the service and defence of one’s homeland, the doctrine of “just war” as well as the ancient topos of pax et bellum. Readily apparent in the image, there are also elements of ethics, the science of the state and the Polish tradition of legal theory. The triumphal arch of Jan Zamoyski constitutes a parenetic mirror of his life and virtues as an “exemplary citizen” and an “ideal civil servant,” simply vir bonus.
Źródło:
Perspektywy Kultury; 2023, 41, 2/1; 105-128
2081-1446
2719-8014
Pojawia się w:
Perspektywy Kultury
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Il viaggio di Enrico di Valois, Re di Francia e Polonia, da Cracovia a Lione (18 giugno – 5 settembre 1574). Apparati festivi dell’entrata in Mantova
The Journey of Henry of Valois, King of France and Poland, from Krakow to Lyon (June 18–September 5, 1574). Festive Apparatus of his Entry into Mantua
Autorzy:
Natta, Federica
Powiązania:
https://bibliotekanauki.pl/articles/37508346.pdf
Data publikacji:
2023
Wydawca:
Akademia Ignatianum w Krakowie
Tematy:
Henric of Valois
Mantua
Gonzaga
Polska
Opis:
Il saggio descrive i preparativi cerimoniali per la visita a Mantova di Enrico di Valois, re della Polonia, nell’agosto del 1574. Il re visitò la città durante il suo viaggio da Cracovia a Lione (18 giugno – 5 settembre 1574), prima di essere incoronato re di Francia. In questa occasione il duca di Mantova Guglielmo Gonzaga preparò archi trionfali, sculture, danze e celebrazioni per Enrico. Il re visitò la città, ma anche le chiese di S. Andrea e S. Pietro, con le loro importanti reliquie. Il saggio ricostruisce le installazioni attraverso la lettura delle cronache, e soprattutto, della corrispondenza e dei materiali del tempo, ritrovati nell’Archivio Gonzaga di Mantova.
The essay describes the ceremonial arrangements for the visit to Mantua by Henry of Valois, King of Poland, in August 1574. The King visited the city of Mantua during his journey from Kraków to Lyon (June 18 – September 5, 1574), before his coronation as King of France. On that occasion the Duke of Mantoa, Guglielmo Gonzaga, prepared triumphal arches, sculptures, dances and celebrations for Henry. The king visited the city but also the churchs, S. Andrea and S. Pietro, with its important relics. The essay reconstructs the installations through the reading of the chronicles, and above all, of the correspondence and materials of the time found in the Gonzaga Archive of Mantua.
Źródło:
Perspektywy Kultury; 2023, 41, 2/1; 181-198
2081-1446
2719-8014
Pojawia się w:
Perspektywy Kultury
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Jean Fabre i Europa wieku świateł. Rec.: Jean Fabre, Stanisław August Poniatowski i Europa wieku świateł, tłum. Jan Maria Kłoczowski, red. Piotr Skowroński, Muzeum Łazienki Królewskie w Warszawie, Warszawa 2022, t. 1–2, s. 436, 654, il.
Autorzy:
Grześkowiak-Krwawicz, Anna
Powiązania:
https://bibliotekanauki.pl/articles/28408695.pdf
Data publikacji:
2023-09-28
Wydawca:
Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Źródło:
Wiek Oświecenia; 2023, 39; 155-160
0137-6942
Pojawia się w:
Wiek Oświecenia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Xavier Magnon, Ariane Vidal-Naquet, Le droit constitutionnel est-il un droit politique? [Czy prawo konstytucyjne jest prawem politycznym?], „Les Cahiers Portalis” 2019, vol. 6, no. 1, pp. 107–128, https://doi.org/10.3917/capo.006.0107
Xavier Magnon, Ariane Vidal-Naquet, Is constitutional law political law? [Le droit constitutionnel est-il un droit politique?], “Les Cahiers Portalis” 2019, vol. 6, no. 1
Autorzy:
Trela, Anna
Powiązania:
https://bibliotekanauki.pl/articles/28409256.pdf
Data publikacji:
2023
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Źródło:
Studia Prawa Publicznego; 2023, 1 (41); 198-201
2300-3936
Pojawia się w:
Studia Prawa Publicznego
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Expression of anti-inflammatory markers IL-2, IL-10, TGF-β1, βDEF-2, βDEF-3 and Cathelicidin LL37 in dairy cattle milk with different health status of the udder
Autorzy:
Šerstņova, K.
Pilmane, M.
Vitenberga-Verza, Z.
Melderis, I.
Gontar, Ł.
Kochański, M.
Drutowska, A.
Maróti, G.
Prieto-Simón, B.
Powiązania:
https://bibliotekanauki.pl/articles/16539162.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
cytokines
interleukins
mastitis
bovine milk
Opis:
Great economic losses to the dairy industry are associated with bovine mastitis, which results in poor milk quality and high treatment costs. Anti-inflammatory proteins play an important role in the suppression of the immune response against invading pathogenic microorganisms and are therefore being studied for possible use in the early diagnosis of mastitis. In our study, we used milk samples from 15 cows of Holstein Friesian breed with different health status (5 healthy, 5 subclinical, and 5 clinical animals), and tested them using immunohistochemical (IHC) analysis to evaluate the presence of IL-2, IL-10, TGF-β1, βDEF-2, DEF-3, and Cathelicidin LL37 proteins. The calculation of positively and negatively stained cells for each biomarker was performed using the semiquantitative counting method. We found the presence of all factors with the exception of Cathelicidin LL37, which was almost absent in milk samples of all animal groups. The significant decrease of IL-10, β-def2, and β-def3 expression levels within the 3 days of sampling, found in the milk of animals with sub- and clinical mastitis, indicates the loss of antiinflammatory protection of the affected cow’s udder. In contrast, the stable increase of IL-2 and TGF-β1 positive cells observed in the milk of mastitis-affected cows, and the similar expression of these factors in the milk of healthy animals, indicate the possible lack of involvement of these cytokines at an early stage of udder inflammation.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 2; 237-248
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Il modo congiuntivo: il caso della lingua polacca e italiana
The subjunctive mood: the case of Polish and Italian
Autorzy:
Paliczuk, Aleksandra
Powiązania:
https://bibliotekanauki.pl/articles/31341233.pdf
Data publikacji:
2022
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Tematy:
subjunctive
Polish
Italian
meaning
grammar
Opis:
Le lingue naturali differiscono non solo nel lessico, ma anche, o forse soprattutto, nella grammatica. L’importanza di alcune strutture grammaticali o la loro frequenza d'uso possono variare tra le lingue. Ci sono lingue che le usano o le descrivono in modo diverso. Nella grammatica polacca contemporanea non troviamo informazioni sul modo congiuntivo. Tuttavia, cercando di confrontarla con altre lingue, come l’italiano, notiamo alcuni fenomeni nella lingua polacca che non sono formalmente descritti, eppure assomigliano al congiuntivo. Tuttavia, un ricercatore, che consulterebbe studi precedenti, potrebbe scoprire che la descrizione della grammatica polacca è cambiata in modo abbastanza significativo e potrebbe essere in grado di effettuare alcune nuove osservazioni. Questo testo è un tentativo di mostrare che nonostante la mancanza di una descrizione formale la lingua polacca usa il congiuntivo, ciò si evince in base ad un confronto con la lingua italiana.
Natural languages differ not only in lexis, but also, or perhaps above all, in grammar. The importance of certain grammatical forms or their frequency of use can vary among languages. There are languages that use them or describe them differently.In the contemporary Polish grammar we will not find information about the subjunctive mood. However, when comparing it with other languages, such as Italian, we will notice certain analogies and phenomena in Polish which are not formally described, and yet they resemble the subjunctive. Nonetheless, a researcher, who will consult older studies, may discover that the description of the Polish grammar changed quite significantly and may be able to find some new insights.This text is an attempt to show that, despite the lack of a formal description, Polish uses the subjunctive, by confronting it with Italian language.
Języki naturalne różnią się nie tylko leksyką, ale także, a może przede wszystkim, gramatyką. Znaczenie niektórych form gramatycznych lub częstotliwość ich używania może różnić się w zależności od języka. Istnieją języki, które ich używają w inny sposób lub opisują je inaczej. We współczesnej gramatyce języka polskiego nie znajdziemy informacji o trybie łączącym. Jednak porównując język polski z innymi językami, np. włoskim, dostrzeżemy pewne zjawiska w języku polskim, które nie są formalnie opisane, a jednak przypominają tryb przypuszczający. Niemniej jednak badacz, który skonsultuje się ze starszymi opracowaniami, może odkryć, że opis gramatyki polskiej zmienił się dość znacząco i być może uda mu się dokonać nowych spostrzeżeń. Tekst ten jest próbą pokazania, że mimo braku opisu formalnego, język polski posługuje się trybem łączącym, co uwidacznia porównanie go z językiem włoskim.
Źródło:
Neophilologica; 2022, 34; 1-21
0208-5550
2353-088X
Pojawia się w:
Neophilologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Il ne faut pas se laisser tromper par la langue : entre syntaxe et sémantique
Don’t Be Fooled by the Language: Between Syntax and Semantics
Autorzy:
Śmigielska, Beata
Powiązania:
https://bibliotekanauki.pl/articles/31341237.pdf
Data publikacji:
2022
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Tematy:
Semantic grammar
predicate
argument
adjoint
modifier
valence
semantic implication
paraphrase
contradiction
Opis:
In this article, Beata Śmigielska describes the questions used to determine the number and nature of arguments of predicates within the framework of Stanisław Karolak’s semantics-based grammar. Since syntactic structures do not directly reflect the semantic structures of predicates, the distinction between arguments and adjunct elements (modifiers) often becomes problematic. This fact is related to the lack of a single methodology by which this can be done in a simple and unambiguous way, resulting in different results of analyses of the same predicates. To solve this problem, it is necessary clearly to define the theory within which we work, because it is the adopted perspective and its well-defined principles that will decide both the path of thought during the research and its results. In her analyses of the selected predicates, Śmigielska defines the tools that can be used in predicate description such as the semantic decomposition of predicates into simpler elements, supplemented, where necessary, by contradiction tests and paraphrasing.
Źródło:
Neophilologica; 2022, 34; 1-19
0208-5550
2353-088X
Pojawia się w:
Neophilologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Już starożytni Rzymianie... O tym, jak (nie) inspiruje prawo rzymskie. Già nell’antica Roma? ‒ Ovvero come il diritto romano non è sempre un modello. Sprawozdanie z konferencji ku pamięci Profesora Witolda Wołodkiewicza, Warszawa, 1-2 czerwca 2022 roku
Autorzy:
Saracyn, Wiktoria
Powiązania:
https://bibliotekanauki.pl/articles/2143488.pdf
Data publikacji:
2022-10-19
Wydawca:
Uniwersytet Kardynała Stefana Wyszyńskiego w Warszawie
Opis:
.
Źródło:
Zeszyty Prawnicze; 2022, 22, 3; 317-321
2353-8139
Pojawia się w:
Zeszyty Prawnicze
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mai dire basta alla pasta. Il discorso delle diete dimagranti nel periodico italiano per uomini “For Men Magazine” (2013—2022)
Never say basta to a plate of pasta. The discourse of slimming diets in the Italian magazine “For Men” (2013—2022)
Autorzy:
Ozimska, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/31341232.pdf
Data publikacji:
2022
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Tematy:
discourse
diet
men’s magazines
Italian language
masculinity
For Men Magazine
Opis:
Using the tools of rhetoric and critical discourse analysis, the paper describes the discourse of slimming diets in the Italian men’s magazine “For Men”. The study covered 49 monthly issues published in 2013—2022. The research has shown the presence of numerous persuasive techniques based on building the credibility of theses presented to the readers (mostly using the argument of authority). There are numerous references to popular topoi that increase the competitiveness of the proposed nutritional regimes. Some techniques influencing the emotions of readers were used to a lesser extent. The discourse of diets is present in every issue of the magazine under study, and much space is devoted to it, creating the impression that it is an important and interesting topic for contemporary Italian readers (permanent columns present). In addition, phenomena such as scientization and medicalization of nutrition, fragmentation of the male body were observed. Many of the examples cited could be found in the Italian women’s press published about 15 years ago.
Źródło:
Neophilologica; 2022, 34; 1-27
0208-5550
2353-088X
Pojawia się w:
Neophilologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mutual relations between the amygdala and pro-inflammatory cytokines: IL-1β and IL-6
Autorzy:
Czerwiec, Katarzyna
Ruciński, Jan
Piwko, Grzegorz
Myślińska, Dorota
Kosiński, Adam
Powiązania:
https://bibliotekanauki.pl/articles/2203182.pdf
Data publikacji:
2022-05-31
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
inflammation
IL-6
amygdala
IL-1β
Opis:
Interleukin 1 (IL-1) and interleukin 6 (IL-6) are typical examples of multfunctonal pro-infammatory cytokines involved in the regulaton of the immune response, hematopoiesis, and infammaton. Both peripheral and intraventricular administraton of these cytokines causes acute phase symptoms, e.g. fever, actvaton of the hypothalamic-pituitary-adrenal axis and psychological depression. The amygdala belongs to the structures of the limbic system involved in the regulaton of the immune response. Increased actvity of immune system may lead to changes in the role of amygdala, medial prefrontal cortex, anterior cingulate cortex or insula. The aim of the study was to present the mutual interactons between the amygdala and pro-infammatory cytokines such as interleukin-1β (IL-1 beta) and interleukin 6 (IL-6). Most of the data included in this review comes from animal studies.
Źródło:
European Journal of Translational and Clinical Medicine; 2022, 5, 1; 40-46
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ochratoxin A and Aflatoxin B1 as Factors of Bone Damage and Neurodegeneration Through the Influence on the Immunomodulation Processes of TNF-α and IL-6 Concentrations
Autorzy:
Radzka-Pogoda, Agnieszka
Radzki, Radosław Piotr
Bieńko, Marek
Szponar, Jarosław
Sokołowska, Barbara
Kulik, Anna
Lewicka, Małgorzata
Borzęcki, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/32874334.pdf
Data publikacji:
2022
Wydawca:
Polskie Towarzystwo Medycyny i Techniki Hiperbarycznej
Tematy:
bone metabolism
bone development
bone remodelling
mycotoxin
aflatoxin B1
ochratoxin A
neurodegeneration
Opis:
The wide distribution of mycotoxins, including aflatoxin B1 and ochratoxin A, in the environment and their influence on living organisms make them an interesting research problem. Numerous complications of intoxication with these substances are known, however, particular attention is paid to the effects on the skeletal and nervous systems. The inflammatory effect, presented by the increase in the concentration of cytokines - IL-6 and TNF-α may influence the immune dysregulation present in bone metabolism disorders, as well as in neurodegeneration. Mycotoxins also contribute to osteodegeneration by modifying vitamin D metabolism. Interestingly, and still unexplored, is the mechanism of intrauterine influence on bone metabolism and neurodegeneration processes. Understanding the above mechanisms may help in monitoring the toxic effects of intoxication with these toxins. It can also help develop methods of therapy for poisoning with this compound, in animals and humans.
Źródło:
Polish Hyperbaric Research; 2022, 3(80); 61-72
1734-7009
2084-0535
Pojawia się w:
Polish Hyperbaric Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Plasma interleukin-1α and interleukin-8 in female dogs with non-metastatic and metastatic malignant mammary gland tumours
Autorzy:
Szczubiał, M.
Łopuszyński, W.
Dąbrowski, R.
Bochniarz, M.
Brodzki, P.
Powiązania:
https://bibliotekanauki.pl/articles/16539196.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
IL-1α
IL-8
canine mammary tumours
plasma
metastases
Opis:
In this study plasma concentrations of IL-1α and IL-8 in 29 female dogs with malignant mammary gland tumours (19 without metastasis and 10 with metastasis) and in 10 healthy control animals were determined. Concentrations of IL-1α and IL-8 were analysed using a specific canine ELISA assay. Mean plasma concentrations of IL-1α and IL-8 were significantly higher (p<0.05) in female dogs with both non-metastatic and metastatic malignant tumours compared to the healthy animals. The concentrations of both tested cytokines were significantly increased (p<0.05) in the dogs with metastasis. In female dogs with mammary carcinomas, the plasma concentration of IL-1α was significantly higher (p<0.05) in the animals with grade 3 tumours compared to the dogs with grade 1 tumours. The concentration of IL-8 was significantly higher (p<0.05) in the dogs with grade 3 tumours compared to that found in the animals with grade 1 and grade 2 tumours. A moderate correlation (r=0.433) was found between IL-1α and IL-8 concentrations in the female dogs. These findings suggest that increased malignancy and invasiveness of canine mammary tumours is associated with an increased production of IL-1α and IL-8 in the tumour microenvironment, which, in turn, leads to an increase in their circulating levels. This may indicate that circulating levels of the cytokines investigated could be considered as diagnostic and prognostic markers in canine malignant mammary tumours. However, further studies in this fields are needed.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 2; 317-324
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł

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