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Wyświetlanie 1-15 z 46
Tytuł:
A convenient method for synthesis of 11-[14C]-loxapine
Autorzy:
Saemian, N.
Shirvani, G.
Matloubi, H.
Powiązania:
https://bibliotekanauki.pl/articles/148682.pdf
Data publikacji:
2005
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
dibenzoxazepine
carbon-14
microwave heating
Opis:
8-Chloro-11-(4-methyl-1-piperazinyl)-dibenz[b,f][1,4]oxazepine labeled with carbon-14 in 11-position has been synthesized as part of a 5-step sequence from potassium [14C] cyanide.
Źródło:
Nukleonika; 2005, 50, 4; 139-141
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A critical review and reinterpretation of bio-, litho- and seismostratigraphic data of the Southern Baltic deposits
Autorzy:
Zachowicz, J.
Miotk-Szpiganowicz, G.
Kramarska, R.
Uścinowicz, Sz.
Przedziecki, P.
Powiązania:
https://bibliotekanauki.pl/articles/1204982.pdf
Data publikacji:
2008
Wydawca:
Państwowy Instytut Geologiczny – Państwowy Instytut Badawczy
Tematy:
pollen and diatoms diagrams
14C datings
bio- litho- and seismostratigraphy
Late Pleistocene
Holocene
southern Baltic Sea
Opis:
The aim of this study was the reinterpretation of the published and unpublished Late-Pleistocene and Holocene pollen and diatom diagrams of deposits from the sedimentary basins of the Southern Baltic Sea and the correlation of the distinguished biostratigraphic units with lithological parameters, seismostratigraphic units. Chronostratigraphic subdivision of the Late Pleistocene and Holocene was also made. To facilitate the correlation and reinterpretation of the results of biostratigraphic (palynological and diatom) analyses, new unified and simplified diagrams were drawn using the POLPAL software. Such diagrams were constructed for all the sites under comparison, even for those of no numerical data. In such cases, the published diagrams were scanned and their percentage values were the basis for new diagrams. A review and reinterpretation of biostratigraphic data show an almost complete lack of palynological documentation and diatom diagrams for the Late Pleistocene period and poor documentation for the Early Holocene. Middle and Late Holocene Baltic muds have the best biostratigraphic documentation and radiocarbon dating, which greatly facilitates their location on the geological time scale. Among the Southern Baltic postglacial sediments three lithostratigraphic units were identified. They differ in their lithological features reflecting the conditions prevalent in the sedimentary basin during deposition. It should be noted that these units meet no formal criteria for distinguishing lithostratigraphic units. Similarly, within the Late Pleistocene and Holocene sediments of Southern Baltic deep-water basins, three main seismostratigraphic complexes have been identified. The integrated analysis of seismoacoustic profiles, lithological profiles of cores and reinterpretated biostratigraphic data allow a correlation of the bio-, litho- and seismostratigraphic units with chronostratigraphic units and Baltic evolutionary phases.
Źródło:
Polish Geological Institute Special Papers; 2008, 23; 117-138
1507-9791
Pojawia się w:
Polish Geological Institute Special Papers
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of genes involved in response to doxorubicin and a GD2 ganglioside-specific 14G2a monoclonal antibody in IMR-32 human neuroblastoma cells
Autorzy:
Horwacik, Irena
Durbas, Małgorzata
Boratyn, Elżbieta
Sawicka, Anna
Węgrzyn, Paulina
Krzanik, Sylwia
Górka, Anna
Drożniak, Joanna
Augustyniak, Ewa
Kowalczyk, Aleksandra
Rokita, Hanna
Powiązania:
https://bibliotekanauki.pl/articles/1038977.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
doxorubicin
GD2 ganglioside
microarray
14G2a
neuroblastoma
mimitin
Opis:
Neuroblastoma is the most common extra-cranial solid tumor of childhood and it is characterized by the presence of a glycosphingolipid, GD2 ganglioside. Monoclonal antibodies targeting the antigen are currently tested in clinical trials. Additionally, several research groups reported results revealing that ganglioside-specific antibodies can affect cellular signaling and cause direct cytotoxicity against tumor cells. To shed more light on gene expression signatures of tumor cells, we used microarrays to analyze changes of transcriptome in IMR-32 human neuroblastoma cell cultures treated with doxorubicin (DOX) or a mouse monoclonal antibody binding to GD2 ganglioside 14G2a (mAb) for 24 h. The obtained results highlight that disparate cellular pathways are regulated by doxorubicin and 14G2a. Next, we used RT-PCR to verify mRNA levels of selected DOX-responsive genes such as RPS27L, PPM1D, SESN1, CDKN1A, TNFSF10B, and 14G2a-responsive genes such as SVIL, JUN, RASSF6, TLX2, ID1. Then, we applied western blot and analyzed levels of RPS27L, PPM1D, sestrin 1 proteins after DOX-treatment. Additionally, we aimed to measure effects of doxorubicin and topotecan (TPT) and 14G2a on expression of a novel human NDUFAF2 gene encoding for mimitin protein (MYC-induced mitochondrial protein) and correlate it with expression of the MYCN gene. We showed that expression of both genes was concomitantly decreased in the 14G2a-treated IMR-32 cells after 24 h and 48 h. Our results extend knowledge on gene expression profiles after application of DOX and 14G2a in our model and reveal promising candidates for further research aimed at finding novel anti-neuroblastoma targets.
Źródło:
Acta Biochimica Polonica; 2015, 62, 3; 423-433
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis Procedure of the Positronium Lifetime Spectra for the J-PET Detector
Autorzy:
Dulski, K.
Zgardzińska, B.
Białas, P.
Curceanu, C.
Czerwiński, E.
Gajos, A.
Głowacz, B.
Gorgol, M.
Hiesmayr, B.
Jasińska, B.
Kisielewska-Kamińska, D.
Korcyl, G.
Kowalski, P.
Kozik, T.
Krawczyk, N.
Krzemień, W.
Kubicz, E.
Mohammed, Muhsin
Pawlik-Niedźwiecka, M.
Niedźwiecki, S.
Pałka, M.
Raczyński, L.
Raj, J.
Rudy, Z.
Sharma, N.
Sharma, S.
Shivani, Shivani
Shopa, R.
Silarski, M.
Skurzok, M.
Wieczorek, A.
Wiślicki, W.
Zieliński, M.
Moskal, P.
Powiązania:
https://bibliotekanauki.pl/articles/1033298.pdf
Data publikacji:
2017-11
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
07.05.Kf
13.30.Ce
14.60.-z
78.47.-p
Opis:
Positron annihilation lifetime spectroscopy has shown to be a powerful tool to study the nanostructures of porous materials. Positron emission tomograph is a device allowing imaging of metabolic processes e.g. in human bodies. A newly developed device, the Jagiellonian PET will allow positron annihilation lifetime spectroscopy in addition to imaging, thus combining both analyses providing new methods for physics and medicine. In this contribution we present a computer program that is compatible with the Jagiellonian PET software. We compare its performance with the standard program LT 9.0 by using positron annihilation lifetime spectroscopy data from hexane measurements at different temperatures. Our program is based on an iterative procedure, and our fits prove that it performs as good as LT 9.0.
Źródło:
Acta Physica Polonica A; 2017, 132, 5; 1637-1640
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Anisotropy of g_{eff} Factor for Ni_{50}Mn_{35.5}In_{14.5} Heusler Alloy
Autorzy:
Dubiel, Ł.
Wal, A.
Stefaniuk, I.
Powiązania:
https://bibliotekanauki.pl/articles/1398339.pdf
Data publikacji:
2017-07
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
76.30.-v
75.20.En
32.10.Fn
Opis:
In this work electron magnetic resonance (EMR) spectra of off-stoichiometric $Ni_{50}Mn_{35.5}In_{14.5}$ Heusler alloy ribbons obtained by melt-spinning method were measured. The EMR measurements were performed on the X-band (9.36 GHz) spectrometer. Angle dependences were registered for three orientations of sample, with the use of uniaxial goniometer at 300. The results exhibited magnetic anisotropy and were used for calculating the principal values of g tensor.
Źródło:
Acta Physica Polonica A; 2017, 132, 1; 91-93
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessing the effect of oral diseases on oral health related quality of life of institutionalized elderly using Oral Health Impact Profile (OHIP-14) questionnaire: a pilot study
Autorzy:
Saxena, A.
Nagarajappa, R.
Naik, D.
Abid, M.
Ramesh, G.
Powiązania:
https://bibliotekanauki.pl/articles/876800.pdf
Data publikacji:
2020
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Źródło:
Roczniki Państwowego Zakładu Higieny; 2020, 71, 3
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessing the Indoor Pollutants Effect on Ornamental Plants Leaves by FT-IR Spectroscopy
Autorzy:
Husti, A.
Cantor, M.
Stefan, R.
Miclean, M.
Roman, M.
Neacsu, I.
Contiu, I.
Magyari, K.
Baia, M.
Powiązania:
https://bibliotekanauki.pl/articles/1398690.pdf
Data publikacji:
2016-01
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
87.14.-g
87.15.B-
87.64.km
92.60.Sz
Opis:
Air pollution has become a mass phenomenon, a major and global problem of modern society, affecting billions of people and environment. People are exposed to various levels of pollutants not just in the outdoor environment, but also in indoors. The quality of life and well-being of employees can be increased by incorporating ornamental plants in the work environment. Among the great variety of plants species able to remove/reduce indoor air pollutants Dracaena deremensis, Sansevieria trifasciata and Ficus elastica were hereby investigated. Their ability to remove chemical pollutants was evaluated in real-life conditions and the changes induced by the environmental stress on the structure and biochemical composition of the plants leaves were evidenced by the Fourier transform infrared spectroscopy. The most pronounced concentration decrease was noticed for the CO₂ (58.33% removed concentration), whereas the mean value of the removed concentration of other chemical pollutants was of ≈ 25%. The Fourier transform infrared spectra analysis revealed that, although the plants are subjected to the chemical pollutants action, they maintain the structure by adjusting their metabolism. A decrease in the overall protein contribution in the amide bands and an increase of the bands assigned to polysaccharide vibrations, illustrate the consequences of the pollution action. Moreover, the chlorophyll presence is evidenced in the IR spectra of all samples by the bands around 1040, 1445, 1620, and 1735 cm^{-1}. The results show that the Fourier transform infrared spectra are an important source of information for the rapid characterization of the chemical structure of the biological systems under environmental stress.
Źródło:
Acta Physica Polonica A; 2016, 129, 1; 142-149
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Badanie efektywności wybranych funduszy inwestycyjnych lokujących aktywa na polskim rynku nieruchomości
Study of effectiveness of selected investment funds with assets in the polish real estate market
Autorzy:
Tomal, Mateusz
Powiązania:
https://bibliotekanauki.pl/articles/953698.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
fundusze inwestycyjne
efektywność
rynek nieruchomości
G11
G14
Opis:
Badanie efektywności funduszy inwestycyjnych jest zjawiskiem dość często obserwowanym. Jednak tego typu analizy w zdecydowanej większości dotyczą funduszy akcji czy obligacji. Wydaje się, że fundusze nieruchomościowe z uwagi na to, że są stosunkowo młodym produktem na polskim rynku finansowym oraz z powodu diametralnie innego celu inwestycji powinny być przedmiotem szerokich badań. Celem prezentowanego opracowania było zbadanie efektywności wybranych funduszy inwestycyjnych lokujących swoje aktywa na polskim rynku nieruchomości w latach 2014–2016. W trakcie badań empirycznych przeanalizowano cztery wybrane fundusze inwestycyjne za pomocą relatywnych oraz bezwzględnych miar efektywności. Wyniki analizy ukazały, że większość funduszy inwestycyjnych działających na rynku nieruchomości osiągały słabe rezultaty, co może wynikać z braku umiejętności i wiedzy zarządzającego funduszem oraz złej polityki inwestycyjnej.
The examination of the effectiveness of investment funds is a frequently observed phenomenon. However, such analyses largely concern stock and bond funds. It appears that due to their relatively young age as products on the Polish financial market and the radically different objective of investment real estate funds should be subject to extensive research. The aim of the presented study was to investigate the effectiveness of selected investment funds with assets in the Polish real estate market in 2014–2016. Throughout the course of empirical research four selected investment funds were examined using relative and absolute measurements of effectiveness. Analysis of data showed that the majority of investment funds operating on the real estate market actually achieved poor results. This may be due to a lack of prior knowledge and expertise of manager presiding over the fund, but also due to bad investment policies.
Źródło:
Finanse i Prawo Finansowe; 2017, 1, 13
2391-6478
2353-5601
Pojawia się w:
Finanse i Prawo Finansowe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biological Action in and out of the Water Window
Autorzy:
Vyšín, L.
Davídková, M.
Wachulak, P.
Fiedorowicz, H.
Bartnik, A.
Krůs, M.
Kozlová, M.
Skála, J.
Dostál, J.
Dudžák, R.
Juha, L.
Powiązania:
https://bibliotekanauki.pl/articles/1029783.pdf
Data publikacji:
2018-02
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
87.14.G-
52.38.-r
Opis:
This study is dealing with the difference of radiation chemical yields of single and double strand breaks induced in plasmid DNA by photons inside and outside of the soft X-ray water window, i.e., in the wavelength range from 2.28 nm to 4.88 nm. Photons were generated by various plasma sources providing nanosecond and sub-nanosecond pulses of extreme ultraviolet, soft X-ray and X-ray radiation. DNA strand breaks were determined by agarose gel electrophoresis. Higher radiation chemical yields of both single and double strand breaks were found using picosecond and nanosecond sources of extreme ultraviolet and X-ray radiation.
Źródło:
Acta Physica Polonica A; 2018, 133, 2; 236-238
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Caracterisation de l'ordre par diffraction d'electrons
Autorzy:
Le Bosse, J. C.
Lopez, J.
Hansali, G.
Wiatrowski, G.
Rousseau, J.
Powiązania:
https://bibliotekanauki.pl/articles/1929266.pdf
Data publikacji:
1993-05
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
61.14.Dc
68.10.Jy
Opis:
CHARACTERIZATION OF THE ORDER BY ELECTRON DIFFRACTION: In the case of a solid with a local atomic order, we can consider only a statistical description of atomic positions. For a homogeneous phase, this description is given by the two-site occupancy correlation function, the three-site occupancy correlation function, ... etc. The local atomic order is investigated by experiments in which the solid is bombarded with a well-collimated monoenergetic beam of particles (here electrons). Starting from a model describing the force law between an electron and an atomic scatterer and from a model of the solid describing the distribution of atoms in space, a computation of elastically backscattered intensities can be carried out. The latter depends on geometrical parameters which are determined in such a way that one gets the best agreement between the results of calculation and the measurements. This work aims to provide the way of proceeding to calculate the diffuse intensity. The main difficulty in this task appears when we undertake to treat the problem of multiple scattering. We provide here a detailed description of a calculation corresponding to the case of the backscattering of electrons at a single crystal surface covered with a partially disordered atomic layer. Assuming that the coverage in adatoms is small and these adatoms are weak scatterers, we can neglect the multiple scattering events inside the layer. This simplifying assumption leads to an expression of the diffuse intensity in terms of: the Fourier transform on the 2D surface lattice of the pair correlation function; the renormalized transition matrices of the different kinds of adatoms.
Źródło:
Acta Physica Polonica A; 1993, 83, 5; 567-580
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 46

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