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Wyszukujesz frazę "CD8+ T cells" wg kryterium: Wszystkie pola

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    Tytuł:
    Effect of tigecycline on the production of selected cytokines and counts of murine CD4+ and CD8+ T cells - an in vitro study
    Autorzy:
    Jasiecka-Mikołajczyk, A.
    Jaroszewski, J.J.
    Maślanka, T.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087626.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    tigecycline
    CD4+ T cells
    CD8+ T cells
    cytokines
    mouse
    Źródło:
    Polish Journal of Veterinary Sciences; 2018, 21, 4; 819-822
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Distribution of CD4 and CD8 T cells in the small intestine of mice after probiotic treatment and Trichinella spiralis infection
    Autorzy:
    Dvoroznakova, E.
    Buckova, B.
    Hurnikova, Z.
    Revajova, V.
    Laukova, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/5886.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    distribution
    CD4 T cell
    CD8 T cell
    small intestine
    mouse
    mice
    probiotic
    treatment
    Trichinella spiralis
    animal infection
    Źródło:
    Annals of Parasitology; 2016, 62, Suppl.
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Serum cytokines and activation ex vivo of CD4plus and CD8plus T cells in chagasic chronic Mexican patients
    Autorzy:
    Cruz-Robles, David
    Vargas-Alarcón, Gilberto
    Ortíz-Muñiz, Rocio
    Reyes, Pedro A.
    Monteon, Victor M.
    Powiązania:
    https://bibliotekanauki.pl/articles/972123.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    Chagas discase
    cytokines
    chronic chagasic cardiomyopathy
    Opis:
    The clinical manifestations of human Chagas disease are associated with several factors, including immunological alterations, in this regard, many studies propose that tissue damage might be more severe in the absence of immune regulatory mechanisms, other factors are the genetic background of host and parasite. Trypanosoma cruzi population is genetically, biochemistry and pathogenic diverse along the Latin-America continent and phylogenetic ally are divided into six intra-species lineages TcI-VI. The TcI lineage has a wide distribution with heterogeneous virulence and pathogenesis within strains. In Mexico, the main circulating lineage is TcI in human infections. We analyzed intracytoplasmic cytokines of unstimulated peripheral T lymphocytes, and the level of cytokines (IL-2, IL-4, IL-12, IL-10, IFN-γ and sIL-2R) in the serum of Mexican chagasic subjects. The population studied consisted of 15 asymptomatic individuals, 17 patients with chronic chagasic cardiopathy (CCC), 20 patients with cardiopathy but negative serology for T. cruzi, and 10 healthy subjects. The analysis of CD4+ cells revealed that CCC and asymptomatic patients have higher CD25+ and CD69 activation markers than controls. The Th1 subset (CD4+/IFN- γ +) was higher in CCC than in asymptomatic and control subjects, whereas Th2 subset was markedly high in asymptomatic subjects. Circulating cytokines were below level detection with the exception of IL-2 and sIL-2R. Infection with Mexican Trypanosoma cruzi strains in asymptomatic chagasic subjects have a tendency for a Th2 response with higher CD8+/IFN-γ T cells. In contrast, CCC patients have low levels of intracellular IFN- γ and IL-2 cytokines. In both groups circulating serum cytokines are below the detectable level.
    Źródło:
    Annals of Parasitology; 2017, 63, 4; 299-308
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Significant expression of Foxp3 in murine extrathymic CD4+CD8+ double positive T cells
    Autorzy:
    Gregorczyk, I.
    Maślanka, T.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087878.pdf
    Data publikacji:
    2017
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    CD4+CD8+ double-positive (DP) T cells
    CD25
    Foxp3
    Treg cells
    mouse
    Źródło:
    Polish Journal of Veterinary Sciences; 2017, 4; 815-817
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of the influence of meloxicam and flunixin meglumine on the apoptosis of peripheral blood CD4plus and CD8plus T cells in calves
    Autorzy:
    Maslanka, T
    Jaroszewski, J.J.
    Markiewicz, W.
    Jabubowski, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/31556.pdf
    Data publikacji:
    2010
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    peripheral blood
    T cell
    calf
    CD4plus T cell
    CD8plus T cell
    apoptosis
    meloxicam
    flunixin meglumine
    lymphocyte
    antiinflammatory drug
    Opis:
    The aim of the study was to determine whether treatment with recommended doses of meloxicam or flunixin had an effect on the apoptosis of peripheral blood T lymphocytes in calves. The study was carried out on 4-5 months old calves (n = 24, 8 per group). Experimental animals were injected subcutaneously with a single dose of 0.5 mg . kg-1 of meloxicam or intravenously with 3 doses of 2.2 mg . kg-1 day-1 of flunixin. The non-treatment animals served as control. Blood samples were taken at day 0 and at days 1, 2, 3, 5, 7 and 14 after the first NSAIDs injection. Apoptosis was determined by flow cytometry using Annexin V-PE/7-AAD staining. The kinetic analysis of apoptosis in the total lymphocyte population, as well as in the CD4+ and CD8+ subsets did not reveal significant differences in the frequency of early apoptotic cells between control and experimental groups throughout the period studied. Although, 24 h after administration of the first dose of NSAIDs, late-stage apoptosis/necrosis was significantly increased in the total lymphocyte population (the meloxicam group), as well as in the CD4+ (the meloxicam group and the flunixin group) and CD8+ (the flunixin group) subsets of T cells. However, this disturbance was transient, relatively poorly expressed and, thus, unlikely to be of clinical significance. Our results indicate that the use of meloxicam or flunixin in accordance with the recommended dosage regimen in cattle do not have a clinically significant influence on apoptosis of peripheral blood T cells.
    Źródło:
    Polish Journal of Veterinary Sciences; 2010, 13, 1; 3-12
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Distribution of CD4plusCD8plus double positive T cells in a mouse model of allergic asthma
    Autorzy:
    Zuska-Prot, M.
    Ziolkowski, H.
    Jaroszewski, J.J.
    Maslanka, T.
    Powiązania:
    https://bibliotekanauki.pl/articles/32502.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The present study describes the distribution of CD4+CD8+ double-positive (DP) T cells in various immune compartments of mice with ovalbumin (OVA)-induced allergic asthma. It was found that the absolute number of DP T cells was considerably increased in the mediastinal lymph nodes and lungs of asthmatic mice as compared with that determined in the healthy subjects. On the contrary, the absolute counts of DP T cells was significantly decreased in the head and neck lymph nodes, and in peripheral blood of OVA-immunized mice. These results suggest that DP T cells may be involved in the pathogenesis of allergic asthma.
    Źródło:
    Polish Journal of Veterinary Sciences; 2016, 19, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    CD4- and CD8-expressing cells found in the bovine and porcine anterior chamber of the eye
    Autorzy:
    Ziółkowski, H.
    Maślanka, T.
    Socha, P.
    Ziółkowska, N.
    Dąbrowski, M.
    Małaczewska, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087714.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    anterior chamber
    CD4+ cells
    CD8+ cells
    DP cells
    cattle
    pig
    Źródło:
    Polish Journal of Veterinary Sciences; 2018, 21, 2; 293-298
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Proliferation and apoptosis of human T cells during replicative senescence - a critical approach.
    Autorzy:
    Jaruga, Ewa
    Skierski, Janusz
    Radziszewska, Ewa
    Sikora, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/1044352.pdf
    Data publikacji:
    2000
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    senescence
    p16
    CD25
    apoptosis
    T cells
    proliferation
    CD8
    Opis:
    Normal human T lymphocytes growing in culture undergo replicative senescence. Previously, we have shown that in our conditions polyclonal T cells cease proliferation after about three weeks (Radziszewska et al., 1999, Cell Biol. Int. 23, 97-103). Now we present results of a more detailed analysis of in vitro growth as well as phenotypic changes of T cells. Cell cycle analysis showed that about 20% of cells were in the S phase untill the 17th day of culture (young cells). The highest number of mitotic cells (phase G2/M; 10%) was observed during the first week of culture. All not dividing senescent cells were stopped in the G1 phase (after the 30th day of culture). The sub-G1 fraction which represents apoptotic cells did not exceed 8% during the whole period until the 30th day of culture. During in vitro T-cell growth, a rather rapid selection to CD3+CD8+ cells occurs. In the presenescent (between the 17th and 30th day) and senescent populations the majority of cells (above 90%) were CD8 positive. We also have checked the expression of α-chain interleukin-2 (IL-2) receptor (CD25). In young and presenescent cells about one third of cells was CD25 positive, but only 15% in the pool of senescent cells. Immunoblotting analysis of p16 protein recognized previously as a marker of senescent T cells, showed its highest and transient expression in presenescent cells. A critical review of the polyclonal T cell replicative senescence model is presented.
    Źródło:
    Acta Biochimica Polonica; 2000, 47, 2; 293-300
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    CD4 and CD8 cells in mice infected with Trichinella spiralis and treated with cyclosporine A
    Autorzy:
    Karmanska, K
    Houszka, M.
    Mista, D.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/836501.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    immunoenzymatic method
    mouse
    infection
    mice
    cell
    T lymphocyte
    immunofluorescent method
    cyclosporin A
    larva
    Trichinella spiralis
    Opis:
    Studies were undertaken to evaluate by parasitological techniques the course of intestinal and muscular invasions in mice infected with Trichinella spiralis and treated with TFX-Thymomodulin (TFX-Th). Studies were conducted on 120 mice of BALB/c and SWISS strains, infected each with a mean invasive dose of 300 T. spiralis larvae. TFX-Th (Thymoorgan GmbH Pharmazie Co. KG, Vienenburg, Germany) was administered subcutaneously at 30 mg/kg body weight. Depending upon duration of TFX-Th administration and stages of intestinal and muscular invasions, three experiments were distinguished in the study. The results indicated that TFX-Th promoted eradication of larvae from muscles, whether administered at the early of the late stage of T. spiralis invasion.
    Źródło:
    Annals of Parasitology; 1994, 40, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    CD4+ and CD8+ cells in mice infected with Trichinella spiralis and treated with cyclosporine A
    Autorzy:
    Karmańska, K.
    Houszka, M.
    Miśta, D.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/2151487.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    immunoenzymatic method
    mouse
    infection
    mice
    cell
    T lymphocyte
    immunofluorescent method
    cyclosporin A
    larva
    Trichinella spiralis
    Opis:
    Studies were undertaken to evaluate by parasitological techniques the course of intestinal and muscular invasions in mice infected with Trichinella spiralis and treated with TFX-Thymomodulin (TFX-Th). Studies were conducted on 120 mice of BALB/c and SWISS strains, infected each with a mean invasive dose of 300 T. spiralis larvae. TFX-Th (Thymoorgan GmbH Pharmazie Co. KG, Vienenburg, Germany) was administered subcutaneously at 30 mg/kg body weight. Depending upon duration of TFX-Th administration and stages of intestinal and muscular invasions, three experiments were distinguished in the study. The results indicated that TFX-Th promoted eradication of larvae from muscles, whether administered at the early of the late stage of T. spiralis invasion.
    Źródło:
    Wiadomości Parazytologiczne; 1994, 40, 4; 357-362
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-10 z 10

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