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Wyszukujesz frazę "Łuczyński, T." wg kryterium: Wszystkie pola


Wyświetlanie 1-6 z 6
Tytuł:
The first record of Aspidogaster limacoides Diesing, 1834 [Aspidogastridae: Aspidogastrea] in Poland
Autorzy:
Popiolek, M
Luczynski, T.
Jarnecki, H.
Powiązania:
https://bibliotekanauki.pl/articles/840930.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parasite
fish
Rutilus rutilus
first record
Polska
roach
Aspidogaster limacoides
Odra River
Aspidogastridae
Aspidogastrea
Źródło:
Annals of Parasitology; 2007, 53, 2
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The first record of Aspidogaster limacoides Diesing, 1834 [Aspidogastridae: Aspidogastrea] in Poland
Autorzy:
Popiołek, M.
Łuczyński, T.
Jarnecki, H.
Powiązania:
https://bibliotekanauki.pl/articles/2143860.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parasite
fish
Rutilus rutilus
first record
Polska
roach
Aspidogaster limacoides
Odra River
Aspidogastridae
Aspidogastrea
Opis:
Aspidogaster limacoides Diesing, 1834 was identified in two specimens of roach (Rutilus rutilus L.) from middle Odra River (Lower Silesia, SW Poland). As the species is new to the Polish parasitofauna, a description, measurements and figure are presented.
Źródło:
Wiadomości Parazytologiczne; 2007, 53, 2; 139-141
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diminished expression of ICOS, GITR and CTLA-4 at the mRNA level in T regulatory cells of children with newly diagnosed type 1 diabetes
Autorzy:
Łuczyński, Włodzimierz
Wawrusiewicz-Kurylonek, Natalia
Stasiak-Barmuta, Anna
Urban, Remigiusz
Iłendo, Elżbieta
Urban, Mirosława
Hryszko, Marek
Krętowski, Adam
Górska, Maria
Powiązania:
https://bibliotekanauki.pl/articles/1040597.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
immunotherapy
T-lymphocytes
autoimmunity
FoxP3
Opis:
Diabetes mellitus is one of the most common chronic diseases in children. T regulatory cells (Tregs) modulate response to autoantigens and probably play a role in pathogenesis of type 1 diabetes (T1DM). The aim of the present study was the assessment of T regulatory cells including their percentages and expression of critical genes in these cells in children with newly diagnosed type 1 diabetes. The examined group consisted of 50 children with T1DM. A flow cytometric analysis of T-cell subpopulations was performed using the following markers: anti-CD4, anti-CD25 and anti-CD127 (=IL-7R). Additionally, T regulatory cells were isolated for assessment of mRNA levels for chosen genes with the real-time RT-PCR technique. The percentages of CD4+CD25highCD127dim/- were very low and did not differ between T1DM and control children. We did not observe any statistically significant differences between healthy and diabetic children in mRNA expression for FoxP3, IL-7R (CD127), IL-8RA, IL-10RA, IL-12A, IL-2RA (CD25), IL-21, STAT1, STAT3, SOCS2, SOCS3, TGF-β1-R1, TGF-β-R2 and TBX-21 genes. Interestingly the mRNA level for CTLA-4, ICOS1, IL-23, IL-27, SMAD3 and GITR were lower in Treg cells of children with diabetes compared to the control patients. No disturbances in the percentages of T regulatory cells in patients with diabetes but diminished expression of some elements important in Treg function could be the result of an immunologic imbalance accompanying the onset of the diabetes. The results of our study should be used in future research in the field of immunotherapy in pediatric diabetes.
Źródło:
Acta Biochimica Polonica; 2009, 56, 2; 361-370
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
CD40 stimulation induces differentiation of acute lymphoblastic leukemia cells into dendritic cells
Autorzy:
Łuczyński, Włodzimierz
Stasiak-Barmuta, Anna
Iłendo, Elżbieta
Krawczuk-Rybak, Maryna
Malinowska, Iwona
Mitura-Lesiuk, Małgorzata
Parfieńczyk, Adam
Szymański, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/1041252.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
immunotherapy
T-lymphocytes
CD40L
acute lymphoblastic leukemia
dendritic cells
Opis:
Despite the very high percentage of long-term remissions in acute lymphoblastic leukemia (ALL) in children, some of them suffer from recurrence of the disease. New treatment modalities, e.g. effective geno- and immunotherapy are needed. The use of neoplasmatic cells to present tumor antigens is one of the approaches in cancer vaccines. ALL cells lack the expression of costimulatory molecules and are poor antigen presenting cells (APCs) for T-cell activation. CD40/40L interaction stimulates B-cells to proliferate, differentiate, upregulate costimulatory molecules and increase antigen presentation. The aim of the study was to test the hypothesis that ALL cells can be turned into professional APCs by CD40L activation. Children with B-cell precursor ALL were enrolled into the study. Mononuclear cells from bone marrow or peripheral blood were stimulated with CD40L and interleukin 4. Results: 1) after culture we noted upregulation of all assessed costimulatory, adhesion and activatory molecules i.e. CD1a, CD11c, CD40, CD54, CD80, CD83, CD86, CD123, HLA class I and II; 2) CD40L activated ALL cells induced proliferation of allogeneic T-cells (measured by [3H]thymidine incorporation). These results confirm the possibility of enhancing the immunogenicity of ALL cells with the CD40L system and indicate that this approach can be used in immunotherapeutic trials.
Źródło:
Acta Biochimica Polonica; 2006, 53, 2; 377-382
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-6 z 6

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