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    Wyświetlanie 1-9 z 9
    Tytuł:
    Parallel Mappings as a Key for Understanding the Bioinorganic Materials
    Autorzy:
    Kuczumow, A.
    Nowak, J.
    Chałas, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/1808388.pdf
    Data publikacji:
    2009-02
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    78.70.En
    87.64.Bx
    87.64.Dz
    87.59.-e
    82.80.-d
    Opis:
    Important bioinorganic objects, both living and fossilized are as a rule characterized by a complex microscopic structure. For biological samples, the cell-like and laminar as well as growth ring structures are among most significant. Moreover, these objects belong to a now widely studied category of biominerals with composite, inorganic-organic structure. Such materials are composed of a limited number of inorganic compounds and several natural organic polymers. This apparently simple composition leads to an abnormal variety of constructions significant from the medical (repairs and implants), natural (ecological effectiveness) and material science (biomimetic synthesis) point of view. The analysis of an image obtained in an optical microscope, optionally in a scanning electron microscope is a topographical reference for further investigations. For the characterization of the distribution of chemical elements and compounds in a material, techniques such as X-ray, electron- or proton microprobes are applied. Essentially, elemental mappings are collected in this stage. The need for the application of an X-ray diffraction microprobe is obvious and our experience indicates on the necessity of using the synchrotron-based devices due to their better spatial resolution and good X-ray intensity. To examine the presence of the organic compounds, the Raman microprobe measurements are good options. They deliver information about the spatial distribution of functional groups and oscillating fragments of molecules. For the comprehensive investigation of bioinorganic material structural and chemical features, we propose the following sequence of methods: optical imaging, elemental mapping, crystallographic mapping, organic mapping and micromechanical mapping. The examples of such an approach are given for: petrified wood, human teeth, and an ammonite shell.
    Źródło:
    Acta Physica Polonica A; 2009, 115, 2; 482-488
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Periodontal condition in patients of the specialist Outpatient Clinics at the Institute of Rural Health in Lublin, Poland
    Autorzy:
    Pawłowicz, A.
    Bachanek, T.
    Klijer, M.
    Chałas, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081572.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    periodontal diseases
    Community Periodontal Index of Treatment Needs (CPITN)
    systemic diseases
    Opis:
    Introduction. Periodontal disease is a chronic inflammation which, if remains untreated, can lead to the loss of teeth and supporting structures. Evidence data support the relationship of periodontal disease with the development and course of diseases such as heart attack, stroke, hypertension, chronic renal diseases, rheumatoid arthritis or diabetes. Objective. The aim of the study was to conduct an assessment of periodontal status and periodontal needs in people from the rural environment who were patients of selected specialist outpatient clinics at the Institute of Rural Health in Lublin, Poland. Materials and methods. The examined population included 450 patients. The Community Periodontal Index of Treatment Needs, which is a measure of the assessment of the selected periodontal symptoms incidence, was used. The obtained data was discussed and analyzed with Chi-square test. Results. The data obtained revealed that a healthy periodontium occurred only in 5.1% of respondents, tartar in 41.6%, pathological pockets of 3.5–5.5 mm in 23.6%, and pockets deeper than 5.5 mm in 5.8% of patients. Most people with healthy periodontium were in the youngest age group. In the analyzed group, 7.1% of patients required specialized comprehensive periodontal treatment, and only 6.5% of the examined persons did not show any need for periodontal treatment. Conclusions. Patients of specialist clinics of the Institute of Rural Health who formed the analyzed group, had affected periodontium which required comprehensive periodontal treatment. The alarmingly high percentage of people over 55 years of age with advanced periodontopathy may translate into an increased risk of cause-and-effect incidence of systemic diseases.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 9-12
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Influence of growth hormone therapy on selected dental and skeletal system parameters
    Autorzy:
    Partyka, M.
    Chałas, R.
    Dunin-Wilczyńska, I.
    Drohomyerska, M.
    Klatka, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081578.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    somatotropic pituitary hypofunction
    malocclusion
    dental age
    Opis:
    Introduction. Growth hormone deficiency (GHD) is one of the main indications for growth hormone therapy. One characteristic of this disease is bone age delay in relation to the chronological age. Pituitary dysfunction negatively affects the growth and development of the jaws and teeth of the child. The secretion of endocrine glands regulates growth, development, and gender differentiation. It also controls the growth of bones and teeth, regulates metabolism of calcium and phosphate, proteins, lipids and carbohydrates. The primary role in the endocrine system is played by the pituitary gland which is responsible for the production of somatotropin[1]. Dysfunction of the pituitary gland has a negative effect on the growth and development of long bones in the body, and may have an adverse effect on the development of maxilla, mandible and dentition of a child. There is some information in the literature that dental age is delayed in short stature children; the replacement of deciduous teeth by permanent teeth is also delayed, and newly erupted permanent teeth often require orthodontic treatment. Applying hormonal therapy positively affects the process of replacement of dentition [2, 3, 4, 5, 6]. Objectives. The aim of the study was to assess bone and dental age, as well as analyze the state of dentition in children diagnosed with GH deficiency treated with growth hormone, depending on the duration of treatment. Materials and method. The study material consisted of 110 children (27 males, 83 females), hospitalized for somatotropin hypopituitarism in the Department of Paediatric Endocrinology and Diabetology at the Medical University of Lublin, Poland. The mean birth age was 13 years (156 months) with a standard deviation of 2 years and 6 months (30 months). 47 children (43%) started treatment with the growth hormone (group starting treatment) and 63 children (57%) whose treatment was started 2–3 years previously (group in the course of treatment). The control group consisted of 41 generally healthy children (15males, 25 females) with ENT problems, such as hypoacusis and a condition after nasal injury, hospitalized in the Department of Paediatric Otolaryngology at the Medical University of Lublin, Poland. The mean age was 11 years and 5 months (137 months) with standard deviation of 2 years and 5 months (29 months). Informed consent was obtained from the parents. The study was approved by the Bioethical Committee at the Medical University of Lublin (Resolution No. KE-0254 /216 /2012).
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 60-65
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Vitamin D, calcium and phosphorus status in children with short stature – effect of growth hormone therapy
    Autorzy:
    Klatka, M.
    Partyka, M.
    Polak, A.
    Terpiłowska, B.
    Terpiłowski, M.
    Chałas, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/28761888.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2021, 28, 4; 686-691
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Long-term clinical performance of experimental glass-ionomer cement with the bi-functional fluid
    Autorzy:
    Chalas, R.
    Wojcik-Checinska, I.
    Strycharz-Dudziak, M.
    Kaminska-Pikiewicz, K.
    Bachanek, T.
    Powiązania:
    https://bibliotekanauki.pl/articles/3528.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    long-term clinical performance
    experimental ionomer
    glass-ionomer
    cement
    dentistry
    bi-functional fluid
    Opis:
    Introduction. Glass-ionomers have the ability to chemically bond to enamel and dentin, and are characterized by longterm fluoride release and absorption of fluoride from surrounding sources. Objective. The aim of the presented long-term clinical trial was to evaluate and compare the three-year clinical performance of the experimental glass-ionomer cement ‘SJZ/W’ with the bi-functional fluid placed in carious and non-carious cavities. Material and methods. Seventy restorations were made in adult patients of both genders. Clinical evaluation was performed at baseline and yearly intervals after placement using Ryge’s scale, considering the surface structure, anatomical form of the restoration and marginal integrity. Results. Immediately after placement, 70 restorations were assessed, 65 of which were subject to clinical evaluation after a year, 63 subject to clinical evaluation after 2 years, and 3-year evaluation was made for 55 restorations. The material showed minor changes in evaluated parameters and no differences were detected between their performance at baseline, and after three years only in anatomical shape. No post-operative sensitivity was recorded. Conclusion. The examined glass-ionomer ‘SJZ/W’ provided an acceptable clinical performance over a three-year period.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2015, 09, 2
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Research on tribological properties of dental composite materials
    Autorzy:
    Dziedzic, K.
    Zubrzycka-Wróbel, J.
    Józwik, J.
    Barszcz, M.
    Siwak, P.
    Chałas, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/103005.pdf
    Data publikacji:
    2016
    Wydawca:
    Stowarzyszenie Inżynierów i Techników Mechaników Polskich
    Tematy:
    dental materials
    biotribology
    friction coefficient
    wear
    Opis:
    Dental practice today used a lot of different materials. This paper evaluates tribological and mechanical properties of two dental materials CeramX and I-Light. Tribological analysisad of samples was conducted at temperature 37°C and in the environment of artificial saliva. The wear rate was evaluated with a ball-on-disc tribotester, in accordance to ASTM G-133 norm. The counterbodies were 6-mm-in-diameter Al2 O3 steel balls. The load of 2, 10 and 20 N was applied. The tests were conducted at 0.15 m/s sliding velocity over a sliding stroke of 1000 m. The changes in the value of the following parameters were measured during the trials: friction coefficient, friction force, temperature and wear depth. After completing the tribological tests the surface of samples was carried out.
    Źródło:
    Advances in Science and Technology. Research Journal; 2016, 10, 32; 144-149
    2299-8624
    Pojawia się w:
    Advances in Science and Technology. Research Journal
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prevalence of dental erosion among 18-year-old adolescents in the borderland districts of Lviv (Ukraine) and Lublin (Poland)
    Autorzy:
    Bachanek, T.
    Hendzel, B.
    Wolańska, E.
    Szybinsky, V.
    Ogonovsky, R.
    Hrynovets, V.
    Samborski, D.
    Nakonieczna-Rudnicka, M.
    Chałas, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081597.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    erosive tooth wear
    dental erosion
    BEWE
    Opis:
    Introduction and objective. Recent epidemiological studies have shown an association between dental erosion occurrence and changes in lifestyle and dietary habits in both developed and developing countries, and now affects different regions of the world. Furthermore, in current literature, studies have shown that the prevalence of erosive tooth wear has increased particularly among the younger population. The aim of the study was to assess the prevalence and severity of erosive tooth wear among 18-year-old adolescents in the districts of Lviv (Ukraine) and Lublin (Poland). Materials and methods. College students (254 subjects) aged 18, living in the Lviv and Lublin districts were examined. Erosive lesions presented in the teeth were assessed on the basis of the BEWE (Basic Erosive Wear Examination) index. Results. Among the 137 patients living in the Lublin district, 70 were females and 67 were males, while in the Lviv district, 60 women and 57 men were examined. In both districts, the following numbers of rural patients were examined: 66 in Lublin district and 56 in Lviv district; for urban inhabitants, the numbers were 71 in Lublin and 61 in Lviv. Analysing the BEWE values, it was noted that higher BEWE values, and resulting from them significant differences were observed in both male and female groups living in Lublin, compared with Lviv inhabitants. Based on clinical examination and statistical analysis, the occurrence of lesions of an erosive character in at least one sextant were observed in 59.85% of patients from Lublin district, and in 42.74% of patients from Lviv district. Conclusions. On the basis of the conducted study in the Polish and Ukrainian groups of 18-year-old adolescents living on the borderland, it can be stated that dental erosion is a problem noticeable in both groups of cohorts, but with higher prevalence in the Lublin district.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 66-70
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The content of selected elements in drinking water, prevalence of caries and hygienic habits of 15-year-olds living in Lviv (Ukraine) and Lublin (Poland)
    Autorzy:
    Bachanek, T.
    Chalas, R.
    Zimenkovsky, A.
    Hendzel, B.
    Wolanska, E.
    Samborski, D.
    Pitura, K.
    Jarosz, Z.
    Szybinsky, V.
    Durlak, W.
    Dudkiewicz, M.
    Dzida, K.
    Tymczyna, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/14102.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Źródło:
    Journal of Elementology; 2018, 23, 2
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of herbal materials on the P-glycoprotein activity and function
    Wpływ surowców roślinnych an aktywność i funkcje glikoproteiny P
    Autorzy:
    Bogacz, A.
    Deka-Pawlik, D.
    Bartkowiak-Wieczorek, J.
    Karasiewicz, M.
    Kujawski, R.
    Kowalska, A.
    Chalas, A.
    Czerny, B.
    Grzeskowiak, E.
    Mrozikiewicz, P.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/72519.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    herbal material
    P-glycoprotein activity
    P-glycoprotein function
    multidrug resistance
    drug transporter
    Opis:
    P-glycoprotein (P-gp) encoded by the MDR1 (multidrug resistance 1) gene is ATP-dependent transporting protein which is localizated in the cell membrane. P-gp is expressed Review Article 130 A. Bogacz, D. Deka-Pawlik, J. Bartkowiak-Wieczorek, M. Karasiewicz, R. Kujawski, A. Kowalska, A. Chałas, B. Czerny, E. Grześkowiak, P. M. Mrozikiewicz mainly in organs with the secretory functions and its physiological role concerns tissue protection against xenobiotics. P-glycoprotein is involved in the permeability barriers of the blood-brain, blood-placenta directly protecting these organs. It participates in the transport of many drugs and other xenobiotics affecting their absorption, distribution, metabolism and excretion. The high P-gp activity in the cell membranes of cancer tissue is a major cause of lack of effectiveness of chemotherapy. Hence, the methods which could increase the sensibility of these pathological cells to cytostatics are still being searched. In the experimental studies it was shown that natural plant substances may have an effect on the expression level and activity of P-glycoprotein. Hypericum perforatum, Ginkgo biloba and Camellia sinensis increase P-gp activity while curcumin from Curcuma longa, piperine and silymarin inhibit this protein. Taking into account a wide substrate spectrum of P-gp, application of our knowledge on interactions of herbals and synthetic drugs should be considered in order to improve drug impact on different tissues.
    Glikoproteina P (P-gp) kodowana przez gen oporności wielolekowej MDR1 to ATP-zależne białko transportowe zlokalizowane w błonach komórkowych. P-gp ulega ekspresji głównie w obrębie narządów pełniących funkcje wydzielnicze, a jej fizjologiczna rola polega na ochronie tkanek przed ksenobiotykami. Glikoproteina P bierze udział w barierach przepuszczalności krew-mózg, krew-łożysko, chroniąc bezpośrednio te organy. Uczestniczy w transporcie leków i innych ksenobiotyków, wpływając na ich absorpcję, dystrybucję, metabolizm i wydalanie. Wysoka aktywność P-gp w błonach komórek nowotworowych jest główną przyczyną braku skuteczności chemioterapii. Poszukiwane są więc sposoby zwiększenia wrażliwości tych patologicznych komórek na cytostatyki. Badane są w tym kierunku naturalne substancje roślinne, ponieważ zaobserwowano ich wpływ na stopień ekspresji oraz aktywność glikoproteiny P. Hypericum perforatum, Ginkgo biloba i Camellia sinensis to surowce zwiększające aktywność P-gp, natomiast kurkumina z korzenia ostryża długiego, piperyna oraz sylimaryna hamują działanie tego białka. Ze względu na tak wielokierunkowe oddziaływanie fitoterapii oraz szerokie spektrum substratowe P-gp, stosując wiedzę na temat interakcji surowców roślinnych z lekami syntetycznymi należy zawsze mieć na uwadze zwiększenie biodostępności stosowanych leków.
    Źródło:
    Herba Polonica; 2013, 59, 4
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-9 z 9

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