Temat: sulfonamide - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Synthesis and biological activity of novel sulfonamides derivatives of various heterocyclic compounds
Autorzy:: Meena, Lakshman R.
Sharma, Vinay S.
Swarnkar, Pawan
Powiązania:: https://bibliotekanauki.pl/articles/1031472.pdf
Data publikacji:: 2020
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: 4-dichlorobenzoic acid
Sulfonamide
anti-fungal
anti-malarial
anti-microbial
Opis:: A novel series of Sulfonamide embedded heterocyclic derivatives were synthesized and well characterized by using 1H NMR, 13C NMR and IR spectroscopic techniques. All the new synthesized compounds were evaluated to their anti-bacterial, anti-fungal and anti- malarial activities. Noticeably, compound 5b was the most potent compound in vitro anti-microbial (S. aureus) with a MTCC value of 96 microgram/ml and compounds 5g and 5j showed most potent activity in vitro anti-fungal (C. albicans) with a MTCC value of 277microgram/ml. Similarly, compound 5e showed high potent activity of anti-malarial (P. falciparum) with mean IC50 value as compared to other synthesized derivatives.
Źródło:: World Scientific News; 2020, 142; 120-134
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 2.

Tytuł:: Synthesis, biological investigations, QSAR and DFT analysis of sulfonamide chalcones as potential: antimicrobial, antifungal and antimalarial agents
Autorzy:: Meena, Lakshman R.
Sharma, Vinay S.
Swarnkar, Pawan
Powiązania:: https://bibliotekanauki.pl/articles/1031835.pdf
Data publikacji:: 2020
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: Claisen-Schmidt condensation
antifungal
antimalarial
antimicrobial
sulfonamide hybrids
α-β-unsaturated ketone
Opis:: Various aromatic aldehydes condense with aryl ketone (N-(4-(phenylsulfonamido)phenyl) acetamide) in presence of aqueous alkaline NaOH to form α, β-unsaturated ketone (N-(4-(N-phenylsulfamoyl)phenyl)cinnamamide derivatives or sulfonamide chalcone derivatives). We were synthesized novel sulfonamides chalcones synthesized through Claisen-Schmidt condensation of aromatic aldehydes and sulfonamide containing acetanilide. All the synthesized compounds were characterized using Mass, FTIR, NMR (1H & 13C) spectra analysis. The synthesized sulfonamide chalcone hybrids were screened antimicrobial activity, antifungal and antimalarial activity.
Źródło:: World Scientific News; 2020, 147; 179-196
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 3.

Tytuł:: Effect of substituents on 4-(substituted phenyl sulfonamide)benzoic acids by IR and NMR spectra
Autorzy:: Muthuvel, I.
Thirunarayanan, G.
Dineshkumar, S.
Powiązania:: https://bibliotekanauki.pl/articles/1059444.pdf
Data publikacji:: 2019
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: 4-(substituted phenyl sulfonamide) benzoic acids
Hammett correlations
IR and NMR spectra
Regression analysis
Opis:: About nine 4-(substituted phenyl sulfonamide) benzoic acid derivatives were synthesized by ultrasound irradiation method. The synthesized sulfonamides were characterized by their physical constants and spectroscopic data. The characteristic infrared SOsym, SOasym, NH and CO vibrations (ν, cm-1), the chemical shifts (δ, ppm) of NH and CO of sulfonamides were assigned and correlated with various Hammett substituent constants and Swain-Lupton parameters using single and multi-regression analysis. From the results of the statistical analysis, the effects of substituents on the spectral frequencies were discussed.
Źródło:: World Scientific News; 2019, 128, 2; 216-233
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

Artykuł

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