Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę "bystander effect" wg kryterium: Temat


Wyświetlanie 1-4 z 4
Tytuł:
Why can’t we just ask? The influence of research methods on results. The case of the “bystander effect”
Autorzy:
Grzyb, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/430703.pdf
Data publikacji:
2016-06-01
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
field experiment
“Bystander effect”
duffusion of responsibility
Opis:
The article discusses the issue of the departure from examining real behaviours in a real environment, a trend in social psychology which has been observed going back several years, and the impact of this phenomenon for social psychology as a scientific discipline. The article presents two studies on the well-known and explored “bystander effect” (Darley, Latane, 1968). This phenomenon is examined in two ways – once by way of a “traditional” field experiment conducted in natural conditions, and once through a survey. As it turned out, the results generated by the two studies were diametrically opposite, and only in the field experiment were we able to achieve a pattern of results consistent with those in the original studies.
Źródło:
Polish Psychological Bulletin; 2016, 47, 2; 233-235
0079-2993
Pojawia się w:
Polish Psychological Bulletin
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Spatial evolutionary games and radiation induced bystander effect
Autorzy:
Krześlak, M.
Świerniak, A.
Powiązania:
https://bibliotekanauki.pl/articles/229460.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
evolutionary games
bystander effect
biomathematical modelling
cellular automata
cancer
Opis:
We present an application of evolutionary game theory to modeling of some processes important from oncological point of view. A studied phenomenon is a radiation induced bystander effect, in which three different strategies (phenotypes) of cells take part. The proposed payoff table of fitness, related to environment adaptation and genetic cell behavior, contains costs/profits of bystander effect, choice of apoptotic pathway, producing growth factors and resistance against bystander effect. We consider a game theory model including spatial cells allocation (the game is played on lattice). We discuss also different polymorphic equilibrium points dependent on model parameters, types of spatial games and players distribution.
Źródło:
Archives of Control Sciences; 2011, 21, 2; 135-150
1230-2384
Pojawia się w:
Archives of Control Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Medium-mediated bystander response of X-ray-irradiated normal human lymphocytes in vitro
Autorzy:
Konopacka, M.
Powiązania:
https://bibliotekanauki.pl/articles/147668.pdf
Data publikacji:
2008
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
bystander effect
human lymphocytes
antioxidant vitamins
chromosomal damage
apoptosis
Opis:
Radiation-induced bystander effects occur in cells that are not directly irradiated but that communicate with irradiated cells via secreted into culture medium soluble factors or gap junction. This effect induces in irradiated and neighboring cells persistent long-term changes that result in delayed death or genomic instability leading to neoplastic transformation. Non-irradiated human normal lymphocytes were incubated in a medium transferred from irradiated another samples of lymphocytes (ICM - irradiation-conditioned medium). Immediately after replacement of the normal or conditioned medium antioxidant vitamins C or E were added. In lymphocytes incubated in a normal medium (control) or conditioned medium, with or without vitamins, the chromosomal damage and apoptosis were estimated. The results show that medium from irradiated cells (ICM) induces in normal lymphocytes micronuclei and condensation of chromatin characteristic of processes of apoptosis. Conditioned medium did not influence cell cycle division. Bystander effect-induced formation of micronuclei was inhibited by antioxidant vitamins C and E, but this had no effect on the induction of apoptosis. These observations suggest that antioxidant vitamins are able to modify radiation-induced bystander effect (by preventing the increase in micronuclei), without inhibiting elimination of damaged cells via apoptosis. This finding could have significant implication for estimating risks of radiation exposure.
Źródło:
Nukleonika; 2008, 53, suppl. 1; 5-8
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The bystander effect: is reactive oxygen species the driver?
Autorzy:
Szumiel, I.
Powiązania:
https://bibliotekanauki.pl/articles/148463.pdf
Data publikacji:
2003
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
bystander effect
reactive oxygen species
ionising radiation
DNA repair
signalling pathways
Opis:
The paper reviews selected examples of the bystander effect, such as clonogenic survival decrease, chromosomal aberrations and mutations. The similarities and differences between the biological effects in directly targeted and bystander cells are briefly discussed. Also reviewed are the experimental data which support the role of reactive oxygen species (ROS), especially *O2-, as mediators of the bystander effect. Endogenously generated ROS, due to activation of NAD(P)H oxidases, play a key role in the induction of DNA damage in bystander cells. All the observed effects in bystander cells, such as alterations in gene expression patterns, chromosomal aberrations, sister chromatid exchanges, mutations, genome instability, and neoplastic transformation are the consequence of DNA damage.
Źródło:
Nukleonika; 2003, 48, 3; 113-120
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

    Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies