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Wyświetlanie 1-3 z 3
Tytuł:
Caffeine and neurodegenerative disorders
Autorzy:
BOGATKO, Karolina
SZOPA, Aleksandra
POLESZAK, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1033776.pdf
Data publikacji:
2014
Wydawca:
Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo
Tematy:
Alzheimer’s disease
Parkinson’s disease
adenosine
caffeine
Opis:
Neurodegenerative disorders are amongst the most dangerous diseases in modern society. At the end of 1990, adenosine receptor antagonists were used to block the adenosine A1 and A2A receptors causing less physical, cellular and molecular damage caused by Alzheimer’s and Parkinson’s diseases. In recent years, an increase in death rate caused by these diseases has been observed among people under 74. Caffeine, as NMDA receptor antagonist, prevents an uncontrolled influx of calcium ions into the interior of the cells exerting a neuroprotective effect and beneficial procognitive effects. There is much evidence that caffeine intake is associated with a reduced risk of Alzheimer’s and Parkinson’s diseases.
Źródło:
Medicina Internacia Revuo; 2014, 26, 103; 89-93
0465-5435
Pojawia się w:
Medicina Internacia Revuo
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Excipients Used in The Non-Coated Tablets - a Review
Autorzy:
POLSKI, Andrzej
IWANIAK, Karol
NALEŚNIAK, Magdalena
POLESZAK, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1033760.pdf
Data publikacji:
2014
Wydawca:
Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo
Tematy:
drug technology
excipients
tablets
Opis:
In modern drug technology excipients fulfill many important roles: antiadherents, binders, disintegrants, fillers, flavours, lubricants, etc. They can modify many properties of tablets including disintegration time, substance release place (stomach, intestine) and time (fast or slow release, non-modified), improvement of taste and flavor, etc. There are many scientific reports that can help choose suitable excipients to produce tablets that have desired properties. That paper was created to arrange knowledge about them.
Źródło:
Medicina Internacia Revuo; 2014, 26, 102; 10-18
0465-5435
Pojawia się w:
Medicina Internacia Revuo
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
RELEASE OF BIOACTIVE SUBSTANCES FROM FORMULATIONS CONTAINING ARTHROSPIRA PLATENSIS (SPIRULINA PLATENSIS)
Autorzy:
Muszyńska, Bożena
Lazur, Jan
Jękot, Barbara
Krakowska, Agata
Szewczyk, Agnieszka
Sułkowska-Ziaja, Katarzyna
Zimmer, Łukasz
Poleszak, Ewa
Opoka, Włodzimierz
Powiązania:
https://bibliotekanauki.pl/articles/895358.pdf
Data publikacji:
2018-10-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
zinc
phenolic compounds
artificial digestive juices
Arthrospira platensis
indole compounds
Opis:
Arthrospira platensis (Spirulina platensis) is a well-known microalga and has been utilized as a medicinal agent and foodstuff by humans since at least 16th century. The aim of this study was to determine zinc content as well as determine phenolic and indole compounds from commercial preparations containing Arthrospira platensis (lyophilizate, tablets, and capsules) before and after extraction with methanol and incubation with artificial digestive juices. The secondary aim of this study was to evaluate the quality of these preparations. The samples were incubated in artificial stomach juice and in intestinal juice. The samples were mineralized and their zinc(II) ions content was estimated using flame absorption atomic spectroscopy (F-AAS). The maximum zinc(II) ions content released into the digestive juices was found to be up to 1.6 mg 100 g-1 of the preparation. Phenolic compounds identified in the examined extracts are as follows: gallic acid; protocatechuic acid; 3,4-dihydroxyphenylacetic acid; p-hydroxybenzoic acid; syringe acid; cinnamic acid; and quercetin. Furthermore, indole compounds identified were 5-hydroxy-L-tryptophan, 5-methyl-L-tryptophan, L-tryptophan, tryptamine, and 5-methyltryptamine. Consequently, it was also found that the distributed Arthrospira platensis in the form of tablets does not disintegrate in the artificial digestive juices. Among the examined preparations, only hard capsules met the requirements of the European Pharmacopeia 8th ed.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 5; 1187-1199
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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