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Tytuł:
Evaluation of dysphagia among patients with chronic cough
Autorzy:
Jamróz, Barbara
Pabian, Maria
Walczak, Joanna
Milewska, Magdalena
Grabczak, Elżbieta
Marta, Dąbrowska
Niemczyk, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1399906.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
dysphagia
FEES
chronic cough
water swallowing test
aspiration
penetration
Opis:
Aim: The aim of the study was to determine the prevalence of dysphagia in patients with chronic cough. Material and methods: Thirty-four consecutive patients. All patients underwent physical examination, ENT assessment, functional phoniatric assessment at rest and speech, Water-Swallow Test (WST), and Fiberoptic Endoscopic Evaluation of Swallowing Disorders (FEES). Furthermore, Reflux Symptom Index (RSI) and Eating Assessment Tool 10 (EAT 10) questionnaires were performed. Results: Results of the RSI and EAT 10 questionnaires showed the risk of reflux and dysphagia in participating patients. WST positive results increase with water volume. Patients presented episodes of spillage, double swallows, penetration, aspiration and residue of food at the hypopharynx. Functional examination showed decrease of laryngeal elevation (33%) and hypertension of external laryngeal muscles. Conclusions: Results of the study showed prevalence of dysphagia in most patients with chronic chough. It seems that phoniatric assessment in those cases should be expanded and FEES examination should comprise an important part.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2018, 7, 2; 1-7
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Crossing language boundaries. The use of English in advertisements in Polish lifestyle magazines
Autorzy:
Dąbrowska, Marta
Powiązania:
https://bibliotekanauki.pl/articles/40057529.pdf
Data publikacji:
2022
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II
Tematy:
multilingual advertising
English as a global language
linguistic landscape
sociolinguistics
Opis:
Advertising is an area open to various types of innovation and a creative use of language. Advertisers use a variety of strategies to attract as many customers as possible, employing enticing visuals, clever puns, detailed descriptions, direct appeals, etc. Yet, if the product is to sell, it appears self-evident that the language of the advertisement should not constitute a barrier. Contrary to this assumption, however, there has been an ever growing trend visible in Polish magazines for the last two decades to formulate parts of or even complete advertisements, not infrequently of Polish brands, in English, despite the fact that English remains a foreign language in Poland, although, admittedly, a very popular one. The present study is conducted within the framework of sociolinguistically informed linguistic landscape analysis. It investigates the visibility of English in the advertising landscape of lifestyle magazines published in Poland, represented by a selection of high quality and mid-range general interest and specialised women’s and men’s magazines. Its objective is to identify tendencies in the manifestations of this newly developing multilingualism in respect of the frequency of using English, the category of advertised products which particularly often appear in such multilingual advertisements as well as the type of magazines which admit such advertisements rather readily. Regarding the linguistic strategies used in the analysed texts, attempts are made to establish whether English tends to be used in complete texts and sentences or only parts of those, and if the latter, which elements of the genre of advertising are especially marked by such language choices and why.
Źródło:
Linguistics Beyond and Within; 2022, 8; 37-54
2450-5188
Pojawia się w:
Linguistics Beyond and Within
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
English as a We-Code: form and Function of English in Facebook Status Updates of Non-Native Female and Male Users
Autorzy:
Dąbrowska, Marta
Powiązania:
https://bibliotekanauki.pl/articles/1026694.pdf
Data publikacji:
2019-09-30
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
English in the Expanding Circle
code choice
genderlect
computer-mediated communication
Opis:
The English language has featured markedly as a popular language of computer-mediated communication, and notably of Facebook posts, written not only by native or second language speakers, but also users of English as a foreign language. The aim of this paper is to investigate the frequency, form and function of English language Facebook profile updates of 110 (55 women and 55 men) users of English representing 41 European, Asian, African and Latin American countries belonging to the Expanding Circle. Approached from the point of view of the code choice as well as the users’ gender, and supported by an online survey data, the study analyses in detail the form of the updates in connection with gender preferences and identifies language contexts and functions users choose to express themselves in English as opposed to their native tongue, thereby demonstrating the role of English as a we-code in a social networking service.
Źródło:
Research in Language; 2019, 17, 3; 231-252
1731-7533
Pojawia się w:
Research in Language
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Safe drive, save life. English as a tool in the promotion of social change in India’s public space
Autorzy:
Dąbrowska, Marta
Powiązania:
https://bibliotekanauki.pl/articles/2054308.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Indian English
linguistic landscape
public service advertisements
rhetoric of social intervention
Opis:
English in India evokes connotations of worldliness, education, class, and power. Although many less socially fortunate groups lack in the English language competence, its presence in the Indian street is increasing, and not only in the context of tourism and marketing. The investigation of the linguistic landscapes of a number of localities in northern India will focus on public service advertisements written in English which convey guidelines for the creation of a healthier Indian society. The study, informed by the rhetoric of social intervention approach, investigates the choice and the frequency of the persuasive rhetorical devices used in the texts. It also discusses which of the three modes of persuasion typically underlie the analysed advertisements, thereby highlighting the preferred approach to tackling local issues and, indirectly, contributing to strengthening the role of English through the positive perception of the messages conveyed.
Źródło:
Linguistica Silesiana; 2021, 42; 153-179
0208-4228
Pojawia się w:
Linguistica Silesiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Challenges in the treatment of chronic cough as observed by a laryngologist and a pulmonologist
Trudności w leczeniu przewlekłego kaszlu okiem laryngologa i pulmonologa
Autorzy:
Dąbrowska, Marta
Arcimowicz, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1399166.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
asthma
chronic cough
difficult to treat chronic cough
gastroesophageal reflux
laryngopharyngeal reflux
upper airway cough syndrome
astma
kaszel trudny do leczenia
kaszel związany z chorobami górnych dróg oddechowych
przewlekły kaszel
refluks krtaniowo- gardłowy
refluks żołądkowo-przełykowy
Opis:
Chronic cough affects about 4–10% of adults and has a negative impact on the patients’ quality of life. Chronic cough may be a symptom of many different diseases and its management should be based on treating the underlying cause. The most common cough cause in adults is chronic bronchitis due to smoking. Next, in non-smoking adults upper airway cough syndrome, gastroesophageal reflux and asthma account for the majority of cough reasons. Despite thorough diagnostics and management in 5–10% adults management of chronic cough is unsuccessful. In difficult-to-treat cough neuromodulators and speech therapy may be effective.
Przewlekły kaszel występuje u 4–10% dorosłych, wpływając negatywnie na ich jakość życia. Może on być objawem wielu chorób, a w większości przypadków jego leczenie powinno mieć charakter przyczynowy. Najczęstszym powodem przewlekłego kaszlu jest przewlekłe zapalenie oskrzeli związane z paleniem papierosów, natomiast wśród osób niepalących są to: choroby górnych dróg oddechowych, choroba refluksowa i astma. Pomimo starannej diagnostyki i prób terapii, u 5–10% chorych z przewlekłym kaszlem nie udaje się uzyskać zmniejszenia jego nasilenia. W takiej sytuacji rozpoznaje się kaszel trudny do leczenia, a jego zmniejszenie można uzyskać stosując rehabilitację logopedyczną lub leki neuromodulujące.
Źródło:
Polski Przegląd Otorynolaryngologiczny; 2020, 9, 1; 11-18
2084-5308
2300-7338
Pojawia się w:
Polski Przegląd Otorynolaryngologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Crisis of Brexit and Other Socio-Cultural Aspects of Silencing the Past through the Example of Anna Burns’ Milkman
Kryzys wywołany brexitem oraz pozostałe aspekty wyciszania przeszłości na przykładzie powieści Milkman Anny Burns
Autorzy:
Frątczak-Dąbrowska, Marta
Jarząb-Napierała, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/2043992.pdf
Data publikacji:
2021-12-27
Wydawca:
Uniwersytet im. Adama Mickiewicza w Poznaniu
Opis:
The present article scrutinizes the phenomenon of a systemic silencing of the past visible in recent socio-political challenges caused by Brexit, especially in the case of the Irish border. Due to the comparative character of the paper, the attention is targeted at a symptomatic amnesia manifested on the British and Northern Irish sides. Postcolonial melancholia, to use Paul Gilroy’s term, facilitated by a systemic whitewashing of British imperial past, is contrasted here with Northern Irish postcolonial amnesia understood as a personal and institutionalised suppression of the difficult memory of colonisation and violence. In what follows, the paper aims to show how these two phenomena meet in the conflict of Brexit and how literature comments on the current political, social and cultural issues such as Brexit based on the example of Anna Burns’ novel Milkman (2018). The article discusses the silence which has surrounded the issue of the Irish Border in Brexit debates, as well as looks at the Northern Irish reluctance to talk about their past as an unsuccessful attempt to escape the demons of the past.
Niniejszy artykuł przygląda się systemowemu uciszaniu przeszłości, które odegrało ważną rolę w dyskursie brexitu, a było szczególnie widoczne w odniesieniu do kwestii granicy irlandzkiej. Artykuł ma charakter porównawczy i skupia się na zjawisku społeczno-kulturowej amnezji widocznej zarówno po brytyjskiej, jak i po północnoirlandzkiej stronie. W artykule używany jest termin postkolonialnej melancholii Paula Gilroya, a opracowanie pokazuje, jak wybielanie brytyjskiej imperialnej historii, które stało się częścią narracji głównego nurtu w dyskursie brexitu, spotyka się z północnoirlandzką postkolonialną amnezją rozumianą jako instytucjonalne wyparcie trudnej pamięci o północnoirlandzkim doświadczeniu kolonizacji i przemocy. Artykuł prezentuje, na przykładzie książki Anny Burns pod tytułem Milkman (2018), jak wspomniane wyżej zjawiska odbijają się w literaturze oraz definiują jej społeczno-kulturowe znaczenie. Ilustruje także, w jaki sposób kształtują one odbiór powieści, która dotyka bieżących problemów społeczno-politycznych.
Źródło:
Porównania; 2021, 30, 3; 179-189
1733-165X
Pojawia się w:
Porównania
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diagnosis and treatment of invasive Candida infections – a review article
Autorzy:
Dąbrowska, Marta
Sienkiewicz, Monika
Kwiatkowski, Paweł
Dąbrowski, Michał
Powiązania:
https://bibliotekanauki.pl/articles/763841.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Tematy:
Candida spp., candidemia, invasive candidiasis, treatment, recommendation
Opis:
Candida albicans is the most common cause of fungal infections worldwide. Invasive candidiasis comprises candidemia and deep-seated candidiasis. Most yeast invasive infections are endogenous with a high mortality. Pathogenesis of candidiasis depends on avoiding host immune responses, as well as the virulence factors of the fungus enabling colonization and invasion of tissues. Adequate source control and antifungal therapy administered within a short time is critical to get a better prognosis. The emergence of drug resistance and the side effects of currently available antifungals are becoming the major problem in the management of Candida spp. infection.
Źródło:
Annales Universitatis Mariae Curie-Sklodowska, sectio C – Biologia; 2018, 73, 1
2083-3563
0066-2232
Pojawia się w:
Annales Universitatis Mariae Curie-Sklodowska, sectio C – Biologia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Achievements of Białystok School of Criminology
Autorzy:
Guzik-Makaruk, Ewa M.
Dąbrowska, Marta
Stachelska, Aleksandra
Powiązania:
https://bibliotekanauki.pl/articles/1374887.pdf
Data publikacji:
2018
Wydawca:
Wyższa Szkoła Policji w Szczytnie
Tematy:
criminology
Bialystok School of Criminology
criminology achievements
University of Bialystok
polish criminologists
Opis:
The aim of this article is to bring the most important achievements of Bialystok School of Criminology closer to the readers. The Faculty of Law of the University of Bialystok, specifically the Department of Criminal Law and Criminology, is one of the leading Polish academic entities conducting extensive research in the field of criminology. In 2016, in the ranking organized by the Rzeczpospolita daily newspaper, the Faculty received the highest score of all the evaluated Polish universities which have law faculties, both state and private, in the area of international cooperation. What is more, Bialystok is the leader in the 2017 ranking of the 25 faculties of law of Polish universities, prepared as a result of the most important evaluation performed every four years by the Ministry of Science and Higher Education and was awarded the highest (A) category. The paper presents not only the international criminology conferences and research that Bialystok School of Criminology has been part of, but also its own initiatives both at the national and international level. For example one of the pioneering ventures on a national scale was the 1st Poland-wide Forum of Young Criminologists held by the Faculty of Law of the University of Bialystok as a regular event. One of the most impressive recent initiatives of BSC was the creation of the International Centre for Criminological Research and Expertise. The paper contains more information about the projects mentioned and others as well as an introduction to the diverse and interdisciplinary topics undertaken by Bialystok’s criminologists.
Źródło:
Internal Security; 2018, 10(1); 85-94
2080-5268
Pojawia się w:
Internal Security
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diagnosis and treatment of mucosa Candida spp. infections – a review article
Autorzy:
Dąbrowska, Marta
Sienkiewicz, Monika
Kwiatkowski, Paweł
Dąbrowski, Michał
Powiązania:
https://bibliotekanauki.pl/articles/763845.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Tematy:
Candida spp., mucosa, treatment, recommendation
Opis:
Candida albicans is the most common cause of fungal infections worldwide. Non-albicans Candida species play an important role in vulvovaginal candidiasis and invasive infections. Most cases of infections are endogenous. In case of patients with immune disorders this opportunistic pathogen causes both surface, systemic infections, and candidemia. Symptoms depend on the area affected. Candidiasis are treated with antimycotics; these include clotrimazole, nystatin, fluconazole, voriconazole, amphotericin B, and echinocandins. The emergence of drug resistance and the side effects of currently available antifungals are becoming a major problem in the management of Candida spp. infection.
Źródło:
Annales Universitatis Mariae Curie-Sklodowska, sectio C – Biologia; 2018, 73, 1
2083-3563
0066-2232
Pojawia się w:
Annales Universitatis Mariae Curie-Sklodowska, sectio C – Biologia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effect of thyme and tea tree oils on morphology and metabolism of Candida albicans
Autorzy:
Rajkowska, Katarzyna
Kunicka-Styczyńska, Alina
Maroszyńska, Marta
Dąbrowska, Mariola
Powiązania:
https://bibliotekanauki.pl/articles/1039294.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Candida albicans
essential oils
morphology
metabolism
enzymatic activity
biochemical properties
Opis:
Members of Candida species cause significant problems in medicine and in many industrial branches also. In order to prevent from Candida sp. development, essential oils are more and more frequently applied as natural, non-toxic, non-pollutive and biodegradable agents with a broad spectrum of antimicrobial activity. The aim of the research was to determine changes in morphology and metabolic properties of Candida albicans in the presence of thyme and tea tree oils. Changes of enzymatic activity of isolates were observed in the presence of both tested essential oils, and they were primarily associated with loss or decrease of activity of all enzymes detected for control. Furthermore, only for 3 out of 11 isolates additional activity of N-acetyl-β-glucosaminidase, α-mannosidase, α-fucosidase and trypsin was detected. Vivid changes in biochemical profiles were found after treatment with tea tree oil and they were related to loss of ability to assimilate d-xylose, d-sorbitol and d-trehalose. The main differences in morphology of isolates compared to the control strain concerned formation of pseudohyphae structures. Both examined essential oils caused changes in cell and colony morphology, as well as in the metabolism of Candida albicans. However, the extent of differences depends on the type and concentration of an essential oil. The most important finding is the broad spectrum of changes in yeast enzymatic profiles induced by thyme and tea tree oils. It can be supposed that these changes, together with loss of ability to assimilate saccharides could significantly impact Candida albicans pathogenicity.
Źródło:
Acta Biochimica Polonica; 2014, 61, 2; 305-310
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
SAFETY OF OMBITASVIR/PARITAPREVIR/RITONAVIR+DASABUVIR IN CHRONIC HEPATITIS C PATIENTS WITH HCV GENOTYPE 1 INFECTION
Autorzy:
Tatara, Tomasz
Dąbrowska-Bender, Marta
Staniszewska, Anna
Duda-Zalewska, Aneta
Powiązania:
https://bibliotekanauki.pl/articles/895553.pdf
Data publikacji:
2019-08-30
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
safety
hepatis C
ombitasvir/paritaprevir/ritonavir+dasabuvir
Opis:
Introduction The assessment of the safety profile of ombitasvir/paritaprevir/ritonavir+dasabuvir in adult chronic hepatitis C patients with confirmed HCV genotype 1 presence. Material and method Evaluation of clinical safety based on the results of primary studies found in the systematic review. The following literature databases were searched: Medline, Embase, Cochrane Library and others. Results Finally two clinical trial met the inclusion criteria. The study included untreated patients (SAPPHIRE I) or patients after unsuccessful therapy (SAPPHIRE II), with genotype 1 infection. In patients without prior treatment the prevalence of the reported adverse events was in general statistically significantly greater in the group on therapy 3D+RBV compared to the placebo group. No statistically significant differences were observed in relation to the risk of serious adverse events or therapy discontinuance due to adverse events. In patients after unsuccessful therapy the prevalence of the reported adverse events was statistically significantly greater in the group on therapy 3D+RBV compared to the placebo group. During the 3D+RBV itching was statistically significantly more frequently reported in the placebo group. Compared to the other adverse events, no statistically significant differences were observed. Conclusions Interferon-free therapies provide a safe therapeutic option in the population of adult patients with chronic genotype 1 hepatitis C, both those untreated and after unsuccessful two-drug PegIFNα-based therapy, patients with HIV co-infection and patients after liver transplantation.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 4; 613-620
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Use of Natural Mineral Sorbents (Zeolite, Bentonite, Halloysite) for Decolorization of Corn-sugar Beet Molasses Vinasse
Zastosowanie naturalnych sorbentów mineralnych (zeolit, bentonit, haloizyt) do usuwania związków barwnych z wywaru kukurydziano-melasowego
Autorzy:
Borowiak, Daniel
Krzywonos, Małgorzata
Dąbrowska, Klaudia
Seruga, Przemysław
Wilk, Marta
Powiązania:
https://bibliotekanauki.pl/articles/1811745.pdf
Data publikacji:
2019
Wydawca:
Politechnika Koszalińska. Wydawnictwo Uczelniane
Tematy:
decolorization
vinasse
mineral sorbents
zeolite
bentonite
halloysite
dekoloryzacja
wywar
sorbenty mineralne
zeolit
bentonit
haloizyt
Opis:
The molasse’s vinasse, because it contains three groups of color processes in it, i.e., melanoidins, hexose alkaline degradation products, and sucrose caramelization products, is one of the most difficult to treat wastewater. Vinasse is toxic to various microorganisms, harmful to soil, groundwater, and vegetation. The aim of the study was using five natural sorbents: halloysite (PJC and KR), two types of zeolites differing in grain thickness and bentonite. The highest decolorization (74% and 62%) was obtained in the process with bentonite and halloysite PJC. Melanoidins and hexose alkaline degradation products were removed when KR and PJC were dosed. After decolorization, in almost all experiments COD and phosphate phosphorus contents were reduced. When bentonite was tested, the organic acids were removed.
Wywar melasowy, ze względu na zawarte w nim trzy grupy związków barwnych tj. melanoidyn, produktów alkalicznego rozkładu inwertu oraz produktów karmelizacji sacharozy, jest jednym z najtrudniejszych do unieszkodliwienia ścieków. Wywar jest toksyczny dla wielu mikroorganizmów, szkodliwy dla gleby, wód podziemnych i roślinności, dlatego przed odprowadzeniem wywaru do środowiska naturalnego substancje barwne muszą zostać z niego usunięte. W pracy sprawdzono jak do usuwania związków barwnych z kukurydziano-melasowego wywaru gorzelniczego nadaje się pięć naturalnych sorbentów mineralnych: haloizyty PJC i KR, dwa zeolity różniące się grubością ziarna oraz bentonit. Najbardziej efektywne odbarwienie (na poziomie 74% i 62%) uzyskano w procesie z zastosowaniem bentonitu oraz haloizytu PJC. Melanoidyny i produkty alkalicznego rozkładu inwertu najskuteczniej zostały usunięte przy udziale bentonitu, natomiast karmele w obecności haloizytów KR oraz PJC. Po procesie dekoloryzacji prawie we wszystkich próbach zmalała zawartość ChZT oraz zawartość fosforu fosforanowego, natomiast wzrosła zawartość ogólnego węgla organicznego. Po procesie dekoloryzacji wywaru z wykorzystaniem bentonitu zmalała również zawartość poszczególnych kwasów.
Źródło:
Rocznik Ochrona Środowiska; 2019, Tom 21, cz. 1; 493--505
1506-218X
Pojawia się w:
Rocznik Ochrona Środowiska
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of the impact of bronchial asthma and hypersensitivity to aspirin on the clinical course of chronic sinusitis with nasal polyps
Autorzy:
Podwysocka, Marta
Dąbrowska, Katarzyna
Fendler, Wojciech
Pagacz, Konrad
Pietruszewska, Wioletta
Powiązania:
https://bibliotekanauki.pl/articles/1397802.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
chronic sinusitis with nasal polyps
hypersensitivity to aspirin
bronchial asthma
clinical course
treatment
Opis:
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a disease with still not enough known pathogenesis despite the development of genetics, immunological and microbiological research. The number of patients with CRS has been constantly growing. The coexistence of CRS, bronchial asthma and aspirin intolerance (aspirin triad) is an adverse prognostic factor with higher risk of recurrences. The aim of study was to compare the severity of CRSwNP depending of coexistence of bronchial asthma and/or aspirin intolerance. The research was performed in the group of 204 patients operated 2009-2013 with 5 years follow-up. Higher nasal polyps growth in groups of patients with aspirin triad and CRSwNP and bronchial asthma in endoscopic examination (p=0,0005 and p=0,0030 respectively) and CT-scan according to Lund-Mackay point scale (p<0,0001 and p=0,0009) was showed. Also, these patients presented increased severity of nasal symptoms before surgical treatment according to VAS scale (p=0,0126 for CRSwNP with bronchial asthma; p=0,0390 for aspirin triad). Similarly, 6 months after surgery the same groups of patients presented higher severity of the disease symptoms (p<0,0001 for aspirin triad’ patients; p=0,0174 for CRSwNP and bronchial asthma’ patients) . Patients with aspirin triad had also statistically more surgeries in past (p=0,001), what proves that recurrences in this group are very likely to be observed in spite of the use of proper conservative treatment. No such differences have been shown in the group of patients with CRSwNP and isolated aspirin intolerance (without bronchial asthma). Allergy to inhaled allergens, hypersensitivity to aspirin are factors significantly worsening the course of CRSwNP. It would be advisable to consider, despite a lack of history of aspirin intolerance, a hypersensititvity to aspirin test in patients with particularly severe CRSwNP, especially those associated with bronchial asthma. It also seems reasonable to carry out such a test on every patient with newly diagnosed CRSwNP and bronchial asthma in order to be able to plan further treatment in this group of patients accordingly including biological treatment with antimonoclonal therapy against interleukin 4, 5 or13.
Źródło:
Polish Journal of Otolaryngology; 2019, 73, 5; 37-43
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of Asian pumpkin (Cucurbita ficifolia) serine proteinase for production of biologically active peptides from casein
Autorzy:
Dąbrowska, Anna
Szołtysik, Marek
Babij, Konrad
Pokora, Marta
Zambrowicz, Aleksandra
Chrzanowska, Józefa
Powiązania:
https://bibliotekanauki.pl/articles/1039621.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
bioactive peptides
Asian pumpkin
casein
Opis:
The main objective of this study was to determine potential application of a serine proteinase derived from Asian pumpkin for obtaining biologically active peptides from casein. The course of casein hydrolysis by three doses of the enzyme (50, 150, 300 U/mg of protein) was monitored for 24 hours by the determinations of: hydrolysis degree DH (%), free amino group content (μmole Gly/g), RP HPLC peptide profiles and by polyacrylamide gel electrophoresis. In all hydrolyzates analyzed antioxidant activities were determined using three tests: the ability to reduce iron ions in FRAP test, the ability to scavenge free radicals in DPPH test, and Fe2+ chelating activity. The antimicrobial activity of obtained peptide fractions was determined as the ability to inhibit the growth of Escherichia coli, Bacillus cereus and Pseudomonas fluorescens in a diffusion plate test. The deepest degradation, expressed as the DH [%] and the free amino group content (67% and 7528 µmole Gly/mg, respectively), was noted in samples hydrolyzed with 300 U/ml of enzyme for 24 hours, while in other samples the determined values were about three and two times lower. The results were in agreement with the peptide profiles obtained by RP HPLC. The highest antioxidative activities determined in all tests were seen for the casein hydrolysate obtained with 300 U/mg protein of serine proteinase after 24 h of reaction (2.15 µM Trolox/mg, 96.15 µg Fe3+/mg, 814.97 µg Fe2+/mg). Antimicrobial activity was presented in three preparations. In other samples no antimicrobial activity was detected.
Źródło:
Acta Biochimica Polonica; 2013, 60, 1; 117-122
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
COMPARISON OF PERSONALIZED AND STANDARD PROPHYLAXIS BASED ON OCTOCOG ALFA IN PEDIATRIC PATIENTS WITH HEMOPHILIA A
Autorzy:
Tatara, Tomasz
Dąbrowska-Bender, Marta
Duda-Zalewska, Aneta
Staniszewska, Anna
Kurek, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/895493.pdf
Data publikacji:
2020-04-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Hemophilia A
octocog alfa
prophylaxis
Opis:
Comparison of personalized and standard prophylaxis prevention therapies based on octocog alfa in pediatric patients with hemophilia A. Studies on a general population (adults and children) demonstrate a statistically significant advantage of personalized prevention therapy over standard prophylaxis prevention therapy in terms of annual bleeding rate (ABR) and annual joint bleeding rate (AJBR) while studies on a pediatric population included insufficiently large populations, however, their results demonstrate a numerical advantage of personalized approach over standard prevention strategy prophylaxis regimen.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 2; 221-218
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 20

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