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    Wyświetlanie 1-7 z 7
    Tytuł:
    Changes of organoleptic quality in potato tubers after application of natural sprout inhibitors
    Zmiany cech sensorycznych bulw ziemniaka po zastosowaniu naturalnych inhibitorów kiełkowania
    Autorzy:
    Grudzińska, M.
    Czerko, Z.
    Borowska-Komenda, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/93503.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Inżynierii Rolniczej
    Tematy:
    organoleptic quality
    inhibitor sprouting
    potato
    storage
    ocena sensoryczna
    naturalne inhibitory kiełkowania
    ziemniak
    przechowywanie
    Opis:
    The aim of this study was to evaluate changes in the sensory properties of the table potato in relation to the use of natural sprout inhibitors during long-term storage. The material for the study consisted in four varieties of potato of the medium early group. The research was carried out in the Plant Breeding and Acclimatization Institute – National Research Institute Branch in Jadwisin in 2014-2015. After harvest potatoes were stored from the end of October to April at 5°C, at the relative humidity of 90-95%, without application of natural sprout inhibitors (control) and using the natural sprout inhibitors (essential oils). After storage, the potatoes were boiled and sensory evaluation was carried out, which includes qualities such as: overcooking of the surface, texture, mealiness, flesh texture, taste and smell. Study results showed that long-term storage of potatoes treated with natural sprout inhibitors – peppermint, caraway and clove essential oils is significant for the changes in overcooking the surface, structure of potatoes and mealiness of tubers after cooking. The taste and smell of potato tubers depended only on the variety.
    Celem podjętych badań była ocena zmian cech sensorycznych ugotowanych bulw ziemniaka jadalnego w zależności po zastosowania naturalnych inhibitorów kiełkowania w czasie przechowywania surowca. Materiałem do badań były cztery odmiany ziemniaka z grupy średnio wczesnych. Badania prowadzono w Instytucie Hodowli i Aklimatyzacji Roślin – PIB Oddział w Jadwisinie w latach 2014-2015. Ziemniaki po zbiorze umieszczono w doświadczalnej przechowalni i przechowywano od października do końca kwietnia w temperaturze 5ºC, przy wilgotności względnej 90-95% bez stosowania naturalnych inhibitorów kiełkowania (próba kontrolna) oraz z zastosowaniem naturalnych inhibitorów kiełkowania (olejki eteryczne z: mięty pieprzowej, kminku i goździka). Po przechowywaniu, ziemniaki gotowano i wykonywano ocenę sensoryczną, w której uwzględniono takie cechy jak: rozgotowanie powierzchni, konsystencja, mączystość, struktura miąższu, smak i zapach. Oceny dokonywał 5-cio osobowy zespół. Na podstawie przeprowadzonej analizy wykazano, że zaprawianie bulw w czasie przechowywania naturalnymi inhibitorami kiełkowania – olejki eteryczne z mięty pieprzowej, kminku i goździka istotnie wpływa na zmiany rozgotowania powierzchni, struktury miąższu i mączystości bulw. Smak i zapach bulw ziemniaka jest cechą odmianową, niezależną od zastosowania inhibitorów.
    Źródło:
    Agricultural Engineering; 2016, 20, 1; 35-43
    2083-1587
    Pojawia się w:
    Agricultural Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Monte Carlo simulations for the Cherenkov Telescope Array Observatory using PL-Grid e-infrastructure
    Autorzy:
    Barnacka, A.
    Bogacz, L.
    Grudzińska, M.
    Janiak, M.
    Komin, N.
    Lamanna, G.
    Moderski, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/305301.pdf
    Data publikacji:
    2012
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
    Tematy:
    very high energy astrophysics
    Monte Carlo simulations
    extensive air showers
    telescope design
    Cherenkov Telescope Array
    Opis:
    The paper presents Monte Carlo simulations carried out during the preparatory phase of the Cherenkov Telescope Array project. The aim of the project is to build the next generation observatory of very high energy gamma rays. During the preparatory phase there is a need to optimize and verify design concepts for various elements of the array. In this paper we describe the main components of the software being used for that purpose, their functions and requirements. Preliminary results of the optimization of the small telescope – one of the several kinds intended for the array, are presented.
    Źródło:
    Computer Science; 2012, 13 (2); 113-122
    1508-2806
    2300-7036
    Pojawia się w:
    Computer Science
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Clinicopathological significance of Epo, EpoR, Ki-67 and Bax expression in colorectal cancer
    Autorzy:
    Lopmerta, K.
    Grudzinska, M.
    Jakubowska, K.
    Samocik, P.
    Kozlowski, L.
    Fudala, A.
    Wincewicz, A
    Koda, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918787.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Colon cancer
    erythropoietin
    erythropoietin receptor
    Opis:
    Introduction: Expression of Epo, a glycoprotein secreted by the fetal liver and the adult kidney in response to cellular hypoxia and its receptor have been described in human solid tumors, such as colon and breast cancer. Purpose: Since activation of Epo-EpoR signaling pathway in erythroid progenitor and precursor cells leads to promotion of proliferation and differentiation or prevention of programmed cell death through Bcl-xl and Bcl-2 it was of interest to investigate expression of Epo, EpoR, apoptosis regulator – Bax and marker of proliferating cells - Ki-67 and assess correlation between them, with regard to clinicopathological variables of colorectal cancer. Materials and methods: The correlations between expression of Epo, EpoR, Bax and Ki-67 in colorectal cancer were analyzed in regard to patient age, sex, primary localization, histopathological type, grading, staging and lymph node invasion. Statistical analyses were performed by using the Spearman rank correlation test applying a significance level of p<0,05. Results: Correlation between Bax and EpoR is positive and statistically significant at all groups of patients except group pT1+pT2. Positive correlation between Bax and Epo is statistically significant at following groups of patients: all patients, age 60, age >60, male, female , primary localization in rectum, primary localization in colon, adenocarcinoma, G2, G3. Statistical analysis revealed no significant correlations between expression of neither Ki-67 with Epo nor Ki-67 with EpoR in all groups of patients. Conclusions: Epo seems to be a pleiotropic cytokine, which can exert its biological effect on several cell types, including neoplastic cells. The effect of Epo-EpoR signaling can differ in various cells and conditions.
    Źródło:
    Progress in Health Sciences; 2018, 8(2); 112-117
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The oncoprotein HBXIP – its functions and roles in oncogenesis
    Autorzy:
    Grudzinska, M.
    Lomperta, K.
    Jakubowska, K.
    Samocik, P.
    Jarząbek, K.
    Kanczuga-Koda, L.
    Wincewicz, A.
    Koda, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918747.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    HBXIP
    survivin
    oncoprotein
    transcription factor
    Opis:
    Nowadays, Hepatitis B X interacting protein (HBXIP) is an object of scientists’ interest worldwide. It is a protein with significant involvement in the development of malignant tumors like breast or ovarian cancer. One of the most important functions of HBXIP is the regulation of cell proliferation, which is related to the progression of a cell cycle. Many studies provide the growing number of evidence that HBXIP plays various important roles, including the regulation of a cell cycle through complexes with survivin, belonging to the inhibitors of apoptosis and interactions with transcriptional factors like STAT4, SP1, TFIID or E2F1. It also has the influence on the promotion of tumor angiogenesis thanks to the association with VEGF and FGF8. Another important role of HBXIP is a reprogramming of glucose metabolism to conditions favorable to growing cancerous cells due to regulating the activation of SCO2 and PDHA1. Furthermore, it impacts on the complement-dependent cytotoxicity, also, HBXIP affects on lipid metabolism through disturbing of metabolic pathways of FAS. According to recent studies, HBXIP can be used as a prognostic biomarker in many tumors, including cervical cancer, ovarian cancer, and esophageal squamous cell carcinoma thanks to the high expression of this protein noted exclusively in these tumor tissues. What is even more interesting, it significantly correlates with clinical attributes like metastasis to lymph nodes or grading and in some cases can potentially be used as the indicator of prognosis of treatment effectiveness. The paper is review through main functions of HBXIP and its possible applications.
    Źródło:
    Progress in Health Sciences; 2018, 8(2); 215-222
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Systemic inflammation markers in blood samples of colorectal cancer patients
    Autorzy:
    Grudzińska, M.
    Jakubowska, Katarzyna
    Koda, M.
    Koda, L.
    Kisielewski, W.
    Smereczański, N.
    Rogoz-Jezierska, N.
    Famulski, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918917.pdf
    Data publikacji:
    2020-06-10
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Colorectal cancer
    neutrophil-to-monocyte ratio
    monocytetolymphocyte ratio
    Opis:
    Introduction: Colorectal cancer (CRC) is one of the most common cancers in Poland. The aim of this study was to investigate the clinical significance of absolute monocyte count, neutrophil-to-monocyte ratio (NMR) and monocytetolymphocyte ratio (MLR) in pre- and postoperative blood samples of patients with CRC. Materials and Methods: We retrospectively reviewed medical records of 160 patients diagnosed with CRC who underwent surgery. Blood samples were obtained within 3 days before and after the surgical treatment. Venous blood samples were also obtained from 42 healthy controls. Results: Pre- and postoperative NMR were significantly higher than healthy controls (p<0.0001; p<0.0001). Moreover, MLR in pre-and postoperative blood samples were higher than voluntaries (p<0.001; p<0.001). The area under the ROC curve for pre and postNMR showed that the parameter exhibits strong diagnostic power (1.000). Pre- and postMLR had moderate diagnostic power amount 0.751 and 0.746. There is also correlation between monocyte count in samples obtained before and after surgery and, lymph node metastasis and size of lymph node metastasis in both cases. PreNMR value was significantly associated with venous and lymphatic invasion and the presence of cancer deposits. PostNMR was found to correlate with presence of distant metastasis and cancer cell deposits (R=0.633, p<0.001; R=0.158, p=0.040). Moreover, preMLR value was correlated with only perineural invasion. Conclusions: Analyzed hematologic markers may be useful as simply obtained parameters, next to histopathological examination, that determine a systemic immune response
    Źródło:
    Progress in Health Sciences; 2020, 10(1); 92-101
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Correlation of clinico-pathologic data with inflammatory cells infiltration in colorectal cancer
    Autorzy:
    Grudzińska, M.
    Jakubowska, K.
    Kańczuga-Koda, L.
    Kisielewski, W.
    Famulski, W.
    Smereczański, N.M.
    Lomperta, K.
    Płoński, M.A.
    Rogoz-Jezierska, N.
    Koda, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918914.pdf
    Data publikacji:
    2020-06-10
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Colorectal cancer
    inflammatory cells
    fibrosis
    Opis:
    Introduction: Colorectal cancer (CRC) is the third most common cancer worldwide. At every phase of cancer development, the inflammatory process has an important impact. Accurate assessment inflammatory cells in the tumour environment in conjunction with clinico-pathologic features can be a relevant prognostic or predictive parameter. Purpose: To analyse inflammatory cell infiltration in CRC tumour mass and correlate with chosen clinico-pathologic parameters. Materials and methods: The study group consisted of 160 patients (64 women, 96 men) diagnosed with colorectal cancer who underwent surgery. Tissue material obtained from routine histopathological diagnosis was stained with H&E and used to assess the type of inflammatory cells in the invasive front and centre of the tumour. Results were subjected to statistical analysis with the age and gender of patients, tumour localization, tumour growth and size, TNM stage, adenocarcinoma type, fibrosis, necrosis, metastasis and tumour invasion (by the Spearman’s correlation coefficient test). Results: The presence of neutrophils in the invasive front of tumour mass was associated with fibrosis and inflammatory cell infiltration in the invasive front of tumour. Macrophages in the invasive front of tumour were found to correlate with tumour growth (expanding and infiltrate). Macrophages and eosinophils were associated with inflammatory cell infiltration in the invasive front and in the centre of tumour. Conclusions: The type of inflammatory cells in the invasive front or centre of the tumour may be useful to prognoses clinical features of colorectal cancer
    Źródło:
    Progress in Health Sciences; 2020, 10(1); 69-76
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Scope ambiguities, monads and strengths
    Autorzy:
    Grudzińska, J.
    Zawadowski, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/103935.pdf
    Data publikacji:
    2017
    Wydawca:
    Polska Akademia Nauk. Instytut Podstaw Informatyki PAN
    Tematy:
    scope ambiguity
    continuation monad
    strength
    Opis:
    In this paper, we will discuss three semantically distinct scope assignment strategies: traditional movement strategy, polyadic approach, and continuation-based approach. Since generalized quantifiers on a set X are elements of C(X), which is the value of the continuation monad C on X, quantifier phrases are interpreted as C-computations, in all three approaches. The main goal of this paper is to relate the three strategies to the computational machinery connected to the monad C (strength and derived operations). As will be shown, both the polyadic approach and the continuation-based approach make heavy use of monad constructs. In the traditional movement strategy, monad constructs are not used but we still need them to explain how the three strategies are related and what can be expected of them with regard to handling scopal ambiguities in simple sentences.
    Źródło:
    Journal of Language Modelling; 2017, 5, 2; 179-227
    2299-856X
    2299-8470
    Pojawia się w:
    Journal of Language Modelling
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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