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Wyszukujesz frazę "Biliński, Tomasz" wg kryterium: Autor


Wyświetlanie 1-10 z 10
Tytuł:
Hypothesis: cell volume limits cell divisions
Autorzy:
Biliński, Tomasz
Bartosz, Grzegorz
Powiązania:
https://bibliotekanauki.pl/articles/1041184.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
replicative aging
Saccharomyces cerevisiae
cell volume
yeast
Opis:
Mammalian somatic cells and also cells of the yeast Saccharomyces cerevisiae are capable of undergoing a limited number of divisions. Reaching the division limit is referred to, apparently not very fortunately, as replicative aging. A common feature of S. cerevisiae cells and fibroblasts approaching the limit of cell divisions in vitro is attaining giant volumes. In yeast cells this phenomenon is an inevitable consequence of budding so it is not causally related to aging. Therefore, reaching a critically large cell volume may underlie the limit of cell divisions. A similar phenomenon may limit the number of cell divisions of cultured mammalian cells. The term replicative (generative) aging may be therefore illegitimate.
Źródło:
Acta Biochimica Polonica; 2006, 53, 4; 833-835
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The rules of aging: are they universal? Is the yeast model relevant for gerontology?
Autorzy:
Bilinski, Tomasz
Zadrag-Tecza, Renata
Powiązania:
https://bibliotekanauki.pl/articles/1039193.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
age related diseases
longevity
yeast
Opis:
The success of experimental biology was possible due to the use of model organisms. It is believed that the mechanisms of aging have a universal character and they are conserved in a wide range of organisms. The explanation of these universal mechanisms by tracing survival curves of model organisms clearly suggests that death of individuals is a direct consequence of aging. Furthermore, the use of unicellular organisms like yeast Saccharomyces cerevisiae to explain the aging processes of multicellular organisms runs the risk of oversimplification. Aging is a very complex process and therefore in this paper we present arguments suggesting that some of these fundamental assumptions require a deep rethinking and verification.
Źródło:
Acta Biochimica Polonica; 2014, 61, 4; 663-669
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Heme synthesis in yeast does not require oxygen as an obligatory electron acceptor.
Autorzy:
Krawiec, Zdzisława
Święciło, Agata
Biliński, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1044224.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
osmotic stress
catalase T
catalase A
heat shock
Saccharomyces cerevisiae anoxia
Opis:
In a previous paper (Krawiec, Z., Biliński, T., Schüller, C. & Ruis, H., 2000, Acta Biochim. Polon. 47, 201-207) we have shown that catalase T holoenzyme is synthesized in the absence of oxygen after treatment of anaerobic yeast cultures with 0.3 M. NaCl, or during heat shock. This finding suggests that heme moiety of the enzyme can either be formed de novo in the absence of oxygen, or derives from the preexisting heme pool present in cells used as inoculum. The strain bearing hem1 mutation, resulting in inability to form δ-aminolevulinate (ALA), the first committed precursor of heme, was used in order to form heme-depleted cells used as inocula. The cultures were supplemented with ALA at the end of anaerobic growth prior the stress treatment. The appearance of active catalase T in the stressed cells strongly suggests that heme moiety of catalase T is formed in the absence of oxygen. This finding suggests the necessity to reconsider current opinions concerning mechanisms of heme synthesis and the role of heme as an oxygen sensor.
Źródło:
Acta Biochimica Polonica; 2000, 47, 4; 1027-2035
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Reactive oxygen species as second messengers? Induction of the expression of yeast catalase T gene by heat and hyperosmotic stress does not require oxygen.
Autorzy:
Krawiec, Zdzisława
Biliński, Tomasz
Schüller, Christoph
Ruis, Helmut
Powiązania:
https://bibliotekanauki.pl/articles/1044432.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
yeast.
osmotic stress
thermotolerance
catalase T
oxygen
Saccharomyces cerevisiae
stress response
heat shock
Opis:
It is shown that oxygen is not absolutely needed for stress-induced synthesis of catalase T in the yeast Saccharomyces cerevisiae. Yeast cells develop heat resistance after exposure to elevated temperatures in anoxia. The levels of catalase activity and thermotolerance are comparable to those in aerobically stressed cells. While these results obviously do not exclude a stress signaling role of reactive oxygen species in some systems, as postulated by other authors, they suggest that the question of the obligatory requirement for reactive oxygen species in other stress signaling systems should be rigorously re-investigated.
Źródło:
Acta Biochimica Polonica; 2000, 47, 1; 201-207
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dependence of the yeast Saccharomyces cerevisiae post-reproductive lifespan on the reproductive potential
Autorzy:
Zadrag-Tecza, Renata
Molon, Mateusz
Mamczur, Jan
Bilinski, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1039620.pdf
Data publikacji:
2013
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
lifespan
oxidative stress
yeast
Opis:
The lifespan of budding yeast cells is divided into two stages: reproductive and post-reproductive. The post-reproductive stage of the yeast's lifespan has never been characterized before. We have analyzed the influence of various mutations on the post-reproductive (PRLS) and replicative (RLS) lifespans. The results indicate that PRLS demonstrates an inverse relationship with RLS. The observed lack of differences in the total lifespan (TLS) (expressed in units of time) of strains differing up to five times in RLS (expressed in the number of daughters formed) suggests the necessity of revision of opinions concerning the use of yeast as a model organism of gerontology.
Źródło:
Acta Biochimica Polonica; 2013, 60, 1; 111-115
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Relationship between the replicative age and cell volume in Saccharomyces cerevisiae
Autorzy:
Zadrag, Renata
Kwolek-Mirek, Magdalena
Bartosz, Grzegorz
Bilinski, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1041168.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
replicative aging
Saccharomyces cerevisiae
cell volume
yeast
Opis:
Reaching the limit of cell divisions, a phenomenon referred to as replicative aging, of the yeast Saccharomyces cerevisiae involves a progressive increase in the cell volume. However, the exact relationship between the number of cell divisions accomplished (replicative age), the potential for further divisions and yeast cell volume has not been investigated thoroughly. In this study an increase of the yeast cell volume was achieved by treatment with pheromone α for up to 18 h. Plotting the number of cell divisions (replicative life span) of the pheromone-treated cells as a function of the cell volume attained during the treatment showed an inverse linear relationship. An analogous inverse relationship between the initial cell volume and replicative life span was found for the progeny of the pheromone-treated yeast. This phenomenon indicates that attaining an excessive volume may be a factor contributing to the limitation of cellular divisions of yeast cells.
Źródło:
Acta Biochimica Polonica; 2006, 53, 4; 747-751
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of stress on the life span of the yeast Saccharomyces cerevisiae.
Autorzy:
Święciło, Agata
Krawiec, Zdzisława
Wawryn, Jarosław
Bartosz, Grzegorz
Biliński, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1044359.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
aging
osmotic stress
superoxide dismutase
catalase
Saccharomyces cerevisiae
heat shock
oxidative stress
Opis:
A correlation is known to exist in yeast and other organisms between the cellular resistance to stress and the life span. The aim of this study was to examine whether stress treatment does affect the generative life span of yeast cells. Both heat shock (38°C, 30 min) and osmotic stress (0.3 M NaCl, 1 h) applied cyclically were found to increase the mean and maximum life span of Saccharomyces cerevisiae. Both effects were more pronounced in superoxide dismutase-deficient yeast strains (up to 50% prolongation of mean life span and up to 30% prolongation of maximum life span) than in their wild-type counterparts. These data point to the importance of the antioxidant barrier in the stress-induced prolongation of yeast life span.
Źródło:
Acta Biochimica Polonica; 2000, 47, 2; 355-364
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Yeast as a biosensor for antioxidants: simple growth tests employing a Saccharomyces cerevisiae mutant defective in superoxide dismutase
Autorzy:
Żyracka, Ewa
Zadrąg, Renata
Kozioł, Sabina
Krzepiłko, Anna
Bartosz, Grzegorz
Biliński, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1041375.pdf
Data publikacji:
2005
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
superoxide dismutase
Saccharomyces cerevisiae
antioxidants
ascorbate
yeast
Opis:
Mutants of Saccharomyces cerevisiae devoid of Cu,Zn-superoxide dismutase are hypersensitive to a range of oxidants, hyperbaric oxygen and hyperosmotic media, show lysine and methionine auxotrophy when grown under the atmosphere of air and have a shortened replicative life span when compared to the wild-type strain. Ascorbate and other antioxidants can ameliorate these defects, which may be a basis of simple tests sensing the presence of antioxidants. In particular, tests of growth on solid medium (colony formation) in the absence of methionine and/or lysine, or in the presence of 0.8 M NaCl can be useful for detection and semiquantitative estimation of compounds of antioxidant properties. Hypoxic atmosphere was found to increase the sensitivity of detection of antioxidants. The test of abolishment of lysine auxotrophy showed a concentration dependence of the antioxidant effects of cysteine and N-acetylcysteine which, however, lost their protective action at high concentration, in contrast to glutathione which was effective also at higher concentrations.
Źródło:
Acta Biochimica Polonica; 2005, 52, 3; 679-684
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-10 z 10

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