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Tytuł:
Study of deuteron motion in a filamentary Plasma-Focus pinch column for different configurations of filaments
Autorzy:
Pasternak, A.
Sadowski, M.
Powiązania:
https://bibliotekanauki.pl/articles/146934.pdf
Data publikacji:
2001
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
deuterons
filamentary pinch
ion trajectories
numerical modeling
plasma focus
Opis:
The motion of deuterons in dynamical filamentary configurations of a PF pinch column has been studied with a three-dimensional numerical model. Apart from magnetic fields, the motion-induced electrical fields as well as ion-ion and ion-electron collisions have been included in the equations of deuteron motion. Calculations were performed for different numbers of filaments and its spatial distributions under different initial conditions. Energy of ions was assumed to be from 10 keV up to 200 keV. The results obtained have shown many possible modes of ion motion and have demonstrated that the current filaments can cause peculiarities observed in the angular distribution of deuterons emitted from the PF pinch column.
Źródło:
Nukleonika; 2001, 46, suppl. 1; 29-32
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Carbon Black--polyethylene Composites Studied by Positron Annihilation
Autorzy:
Dębowska, M.
Rudzińska-Girulska, J.
Pasternak, A.
Poźniak, R.
Powiązania:
https://bibliotekanauki.pl/articles/2007961.pdf
Data publikacji:
1999-04
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
71.60.+z
78.70.Bj
82.30.Hk
Opis:
Preliminary results of positron annihilation lifetime measurements, performed for carbon black-LDPE composites with three kinds of carbon black (PRINTEX XE2, VULCAN XC-72, and SAKAP 6) are presented. Four components with lifetimes τ$\text{}_{1}$≈ 120 ps, τ$\text{}_{2}$≈340 ps, τ$\text{}_{3}$≈1.2 ns, τ$\text{}_{4}$≈2.8 ns occurred to be the best fitted to measured positron lifetime spectra. The presence of carbon black resulted only in reduction of intensities of the components with the lifetimes τ$\text{}_{1}$, τ$\text{}_{3}$, τ$\text{}_{4}$ (originating in our opinion from the annihilation of the positronium) and increase in the intensity of the component with the lifetime τ$\text{}_{2}$. The intensities depend both on the content of carbon black and its kind as well. The strongest influence of the carbon black of the highest specific surface area (PRINTEX XE2) has been observed at the intensities which correlate well with the results of studies of resistivity and tensile strength for the same samples.
Źródło:
Acta Physica Polonica A; 1999, 95, 4; 509-514
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dynamic stability of a cracked pipe conveying fluid and resting on a Pasternak elastic foundation
Autorzy:
Lolov, Dimitar
Lilkova-Markova, Svetlana
Powiązania:
https://bibliotekanauki.pl/articles/2203084.pdf
Data publikacji:
2022
Wydawca:
Politechnika Śląska. Wydawnictwo Politechniki Śląskiej
Tematy:
pipe
fluid
dynamic stability
crack
critical velocity
Pasternak elastic foundation
rura
płyn
stabilność dynamiczna
pęknięcie
prędkość krytyczna
Opis:
Pipeline transport is used worldwide in many sectors of the economy. Its main advantages are continuity of transport, large transportation volumes, small energy consumption, safety, reliability and high environmental benefits. However, the safety problems of pipes attract much interest in science and industry. This paper deals with a cracked pipe with a static scheme of a simply supported beam. It rests along its entire length on a Pasternak elastic foundation. The flowing fluid is considered non-compressible and heavy. The Galerkin method is employed to approach the problem numerically. Conclusions are drawn based on the influence of the crack and the parameters of the Pasternak elastic foundation on the critical flow velocity of the fluid.
Źródło:
Zeszyty Naukowe. Transport / Politechnika Śląska; 2022, 117; 103--113
0209-3324
2450-1549
Pojawia się w:
Zeszyty Naukowe. Transport / Politechnika Śląska
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Light-mediated host searching strategies in a fish ectoparasite, Argulus foliaceus L. [Crustacea: Branchiura]
Autorzy:
Mikheev, V.N.
Mikheev, A.V.
Pasternak, A.F.
Valtonen, E.T.
Powiązania:
https://bibliotekanauki.pl/articles/837834.pdf
Data publikacji:
1999
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parasite
fish
Argulus foliaceus
Branchiura
Crustacea
ectoparasite
host
Źródło:
Annals of Parasitology; 1999, 45, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zinc in medicine and treatment
Cynk w medycynie i lecznictwie
Autorzy:
Horecka, A.
Pasternak, K.
Powiązania:
https://bibliotekanauki.pl/articles/14421.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Opis:
Zinc is an essential and the second most abundant trace element in humans. It is critical for the growth, development and differentiation of cells, as well as for RNA transcription, DNA synthesis, cell division and cell activation. Zinc deficiency affects mainly functions of the immune system, but other consequences include inferior sperm activity, skin lesions, growth retardation, impaired wound healing, anemia and gastrointestinal disorders. Zinc supplementation protects against the hepatotoxic effects of alcohol, enhances the transport of water and electrolytes across the intestinal mucosa and improves immune and anti-inflammatory responses. Zinc is also known as an essential mineral for normal mobilization of vitamin A from the liver to the plasma. Besides, it increases the promoter response to 1,25-dihydroxyvitamin D in osteoblasts. On the other hand, excessive amounts of free zinc in tissues are toxic and accelerated zinc accumulation of zinc is a potent killer of neurons and glial cells. Over 300 signaling molecules and transcription factors contain zinc as a cofactor. Free zinc in immune and tumor cells is regulated by 14 distinct zinc importers (ZIP) and transporters. An elevated amount of zinc transporters LIV-1, a subfamily of ZIP zinc transporters, appears in estrogen receptor–positive breast cancer and has been used as a reliable breast cancer marker. However, the fact that malignant cells are unable to accumulate zinc is an important factor in the development and progression of malignancy of prostate cancer.
Źródło:
Journal of Elementology; 2014, 19, 2
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selenium in medicine and treatment
Selen w medycynie i lecznictwie
Autorzy:
Fraczek, A.
Pasternak, K.
Powiązania:
https://bibliotekanauki.pl/articles/14135.pdf
Data publikacji:
2013
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Opis:
Selenium, one of non-metals, has attracted great interest among many researchers over the last years. Properties of selenium were first mentioned back in the 12th century. Selenium exists in two forms, organic and inorganic one. But whatever the form of supplementation, it is an essential micronutrient conditioning many vital functions. Large-scale research has shown that it has many important properties, including antioxidant ones, for living organisms. It is incorporated in many enzymes and proteins. Numerous studies on this element have demonstrated its beneficial effects, mainly on the cardiovascular and nervous systems. It also contributes to reduction in the incidence of many neoplastic diseases. However, despite numerous desirable effects of this element in the human body, it should be remembered that selenium is also a toxic substance with a narrow therapeutic index. Its excessive consumption contributes to the development of a condition called selenosis. The recommended dose of selenium, depending on the patient’s age, ranges from 25 to 70 μg 24 h–1. However, selenium in excess of 700 μg 24 h–1 shows strong toxicity. Therefore, adequate selenium supplementation is crucial. Nonetheless, despite numerous studies on selenium and its biological role, this trace element still raises many unresolved questions.
Źródło:
Journal of Elementology; 2013, 18, 1
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mercury in medicine and health service
Rtęć w medycynie i lecznictwie
Autorzy:
Osinka, A.
Pasternak, K.
Powiązania:
https://bibliotekanauki.pl/articles/15254.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Opis:
People are most often exposed to mercury in water, amalgam dental fillings, vaccines with ethylmercury as a preservative and in methylmercury containing fish. Foetuses and children are most susceptible to toxic mercury, which passes to their organisms through the placenta or with mother’s milk. Distribution of mercury in organs depends on the type of compound absorbed and duration of exposure. Mercury is mainly absorbed through the respiratory system. There are two types of mercury poisoning: acute and chronic. The critical organs for acute poisoning with mercury vapour are the lungs. Acute poisoning develops when large amounts of mercury are inhaled, which may lead to acute bronchitis, bronchiolitis and pneumonia. Chronic exposure to mercury vapour primarily affects the central nervous system. Mercury is considered as a contributing factor in aetiology of numerous disorders, including neurologic, renal, immunological, cardiologic, reproductive or even genetic abnormalities. Studies have demonstrated the correlation between mercury toxicity and pathogenesis of Alzheimer’s or Parkinson’s disease, autism and multiple sclerosis. Mercury may be involved in four processes which lead to genotoxicity: generation of free radicals and oxidative stress, effects on microtubules and on DNA repair mechanisms as well as direct interaction with DNA molecules.
Człowiek najbardziej narażony jest na kontakt z rtęcią zawartą w wodzie, amalgamatach w plombach dentystycznych emitujących pary rtęci, szczepionkach z etylortęcią stosowaną jako środek konserwujący, metylortęcią w rybach. Płód i dzieci są bardziej podatne na toksyczną rtęć. Matki spożywające w swojej diecie toksyczną rtęć mogą narazić na jej działanie swoje potomstwo, ponieważ rtęć może przechodzić przez barierę łożyskową lub z mlekiem matki do organizmu dziecka. Rozmieszczenie rtęci w narządach zależy od rodzaju związku wchłoniętego do organizmu i czasu trwania ekspozycji. Główną drogą wchłaniania tego metalu jest układ oddechowy. Można wyróżnić dwa rodzaje zatruć rtęcią: ostre i przewlekłe. Narządem krytycznym w zatruciach ostrych parami rtęci są płuca. Gdy do organizmu dostaje się duża ilość rtęci drogą oddechową, może rozwinąć się ostre zapalenie oskrzeli, oskrzelików i zapalenie płuc. Natomiast w przypadku przewlekłego narażenia na pary rtęci układem krytycznym jest ośrodkowy układ nerwowy. Ta postać choroby występuje w przypadku długotrwałego narażenia na niskie stężenia par rtęci. Rtęć jest uznana za czynnik przyczynowy różnego rodzaju zaburzeń, w tym neurologicznych, nefrologicznych, immunologicznych, kardiologicznych, rozrodczych, a nawet genetycznych. Badania wykazały korelację między toksycznością rtęci a patogenezą choroby Alzheimera lub choroby Parkinsona, autyzmem i stwardnieniem rozsianym. Rtęć może być zaangażowana w cztery procesy, które prowadzą do genotoksyczności: wytwarzanie wolnych rodników i stresu oksydacyjnego, działanie na mikrotubule, wpływ na mechanizmy naprawy DNA i bezpośrednią interakcję z cząsteczkami DNA.
Źródło:
Journal of Elementology; 2014, 19, 1
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Calcium and phosphorus in medicine and treatment
Wapń i fosfor w medycynie i lecznictwie
Autorzy:
Maziarka, A.
Pasternak, K.
Powiązania:
https://bibliotekanauki.pl/articles/15580.pdf
Data publikacji:
2013
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Opis:
Calcium and phosphorus are essential for skeletal mineralization and perform a wide array of other biological functions. Calcium is a prime intracellular signalling molecule. It is also involved in muscle contractions (including the myocardium), digestion and blood coagulation. (T HEOBALD 2005) Phosphorus is an intrinsic constituent of many organic substances such as nucleotides, nucleosides, phosphoamino acids and proteins, phospholipids, phosphoglycans and others (H UANG , M OE 2011). In addition, it plays a critical role in cellular signalling through phosphorylation of proteins and other substances (S HAIKH et al. 2008). The present paper focuses on the role of these two elements in skeletal mineralization, and their use in treatment and medicine. First, it briefly discusses the calcium and phosphorus homeostasis, which occurs in three major organs: kidneys, intestines and bones, and involves an integrated hormonal system which maintains their normal serum levels. Moreover, disorders relevant to their abnormally high levels, hypercalcaemia and hyperphosphataemia, and excessively low levels, hypocalcaemia and hypophosphataemia, are described. Additionally, the physiology and pathology of bone as a prime store of both calcium and phosphorus are presented. Adequate intakes of these nutrients are essential for achieving the peak bone mass (PBM). A negative balance results from age-related bone loss, hence possible osteoporosis. This skeletal disorder is characterized by compromised bone strength, thus predisposing to an increased risk of fractures. One of the pharmacological interventions used in the treatment of osteoporosis is the administration of bisphosphonates. They inhibit the action of osteoclasts, prevent further bone losses and improve it strength (F ERRONE , G ERACI 2007). In the final part of the article, calcium phosphate based-ceramics, such as coralline hydroxyapatite, calcium hydroxyapatite (HAp), tri-calcium phosphate (TCP), bioglass, calcium phosphate cements (CPC) and their clinical applications are described.
Źródło:
Journal of Elementology; 2013, 18, 3
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nutritional value of żentyca, a traditional Polish sheep whey product - preliminary results
Autorzy:
Kawecka, A.
Pasternak, M.
Powiązania:
https://bibliotekanauki.pl/articles/1192485.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Tematy:
sheep
traditional product
whey
żentyca
nutritional value
Opis:
In Poland, whey from the production of traditional mountain cheeses is used to make żentyca, one of several traditional products made from milk from Polish mountain sheep raised in the Polish Carpathian Mountains. Żentyca is produced by heating whey to 90°C, that is the temperature at which the whey proteins coagulate and, by being lighter, they form a tender skin on the surface of liquid heated in the cheese vat. This skin is removed from the surface and with a little of remaining whey it is poured as żentyca into a wooden barrel, where it undergoes fermentation by own natural microflora. Research on this unique product is very rare, so the purpose of our study was to evaluate the nutritional and dietary value of żentyca depending on the production date. The samples were taken in shepherd’s huts located along the “Oscypek Trail”, during the sheep grazing period in the Carpathian Mountains, at the beginning (May) and the end (September) of the period. The tested traditional product was characterized by high mean dry matter content and low pH. The study proved that the month in which żentyca was made had an impact on the product quality. Żentyca made from milk produced at the onset of the grazing period contained more protein, lactose and phosphorus but less fat than the product made in the late grazing period. The production month also had influence on percentages of individual protein fractions, and over 60% of the analysed amino acids had varied shares in the protein depending on the żentyca production date. It was found that żentyca is a product of high nutritional and dietary value which depends on the period of production.
Źródło:
Journal of Elementology; 2020, 25, 4; 1509-1516
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Complete response to pixantrone as a salvage therapy in a relapsed/refractory diffuse large B-cell lymphoma
Autorzy:
Pasternak, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1035645.pdf
Data publikacji:
2020
Wydawca:
Medical Education
Tematy:
DLBCL lymphoma
cardiotoxicity
pixantrone
Opis:
Diffuse large B-cell lymphoma (DLBCL) is an aggressive form of non-Hodgkin lymphoma (NHL). It is one of the most common form of the disease. A combination of chemotherapy with anthracycline and a monoclonal antibody targeting CD20 is used as a I line therapy. About two out of three people with DLBCL achieve and maintain complete remission after this treatment. In case of relapse or refractory disease a salvage high‑dose chemotherapy followed by autologous stem cell transplantation (HD-ASCT) is the standard of care. Patientrs who relapse after HD-ASCT have a very poor prognosis. Pixantrone is a new anthracycline derivative registered to treat relapsed/refractory DLBCL in adult patients. It is a cytostatic agent with a reduced cardiotoxicity comparing to classic anthracyclines. Herein, we report two cases of relapsed/refractory DLBCL treated with pixantrone as a salvage therapy. The first case concernes a 58-year-old female patient with a diagnose of DLBCL, who relapsed after four prior lines of therapy (R-CHOP, ICE, HD-Mtx, CSN radiation) and achieved complete remission after pixantrone therapy, but died of acute myeloid leukemia 3 months after the end of treatment. Second case is a story of a 75-year-old female patient treated with two prior lines of treatment (R-CHOP, R-IVE), who achieved complete remission after a III line of therapy with pixantrone. Pixantrone monotherapy proves to be effective in relapsed/refractory DLBCL. This treatment is well tolerated in a group of elderly patients and can be also used in a group of patients with a limited cardiac function.
Źródło:
OncoReview; 2020, 10, 2; 62-68
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sustainable restoration of the roof of a large indoor pool
Autorzy:
Pasternak, H.
Powiązania:
https://bibliotekanauki.pl/articles/403155.pdf
Data publikacji:
2011
Wydawca:
Politechnika Białostocka. Oficyna Wydawnicza Politechniki Białostockiej
Tematy:
basen kryty
dach
korozja
large indoor pool
roof
corrosion
Opis:
During an inspection of the roof of an indoor pool from 1971 in Potsdam (Germany) it was observed, that the roof and the column structures of the building are partially damaged by corrosion. The roof construction is a suspended simple-bent pre-stressed shell between two stiff edge beams. The span of the roof is 39.5 m. The edge beams are supported by A-frames. After further investigation on the damaged areas (including tension tests, tension tests on notched tendons with different load cycles, tests of the bearing capacity of sleeve splices and screw nuts) the conclusion was that the joint of the tension rod and the concrete column had to be restored. This was accomplished through the attaching of a new supporting construction to the existing parts, which took over the load from the old connection. At both sides of the columns pre-stressed DYWIDAG-single-tendons (St1080/1230, diameter of 36 mm) were used. They have to bear a maximal tension force of 835 kN. With this unusual restoration technique, a fast and relative inexpensive retrofitting of the construction could be carried out. The existing construction had to be modified only marginal, and the typical appearance of the building was preserved. This solution stands for sustainability.
Źródło:
Budownictwo i Inżynieria Środowiska; 2011, 2, 4; 631-637
2081-3279
Pojawia się w:
Budownictwo i Inżynieria Środowiska
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A New System for Acoustoelectronic Gas Sensors Analysis
Autorzy:
Jasek, K.
Miluski, W.
Pasternak, M.
Powiązania:
https://bibliotekanauki.pl/articles/1399357.pdf
Data publikacji:
2013-09
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
43.35.Pt
46.35.+z
68.35.Ja
Opis:
Typical approach to the surface acoustic waves sensors response analysis is based on the use of self-oscillating circuits with surface acoustic wave device working inside positive feedback loop of an amplifier. Such kind of parametric measurement allows to track the center frequency of the sensor changes in particular. The method is widely used mainly due to their relative simplicity. Unfortunately, it has many disadvantages like frequency (phase) instability, sensitivity to unwanted factors, surface acoustic wave substrate mass-load limit etc. A new system to the analysis of surface acoustic wave gas sensors response as well as an exemplary measurement results are described in the paper. The presented system make the first step to the more complex conception realization.
Źródło:
Acta Physica Polonica A; 2013, 124, 3; 445-447
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Primary Adenocarcinoma of the Appendix – A Case Report
Autorzy:
Pasternak, Artur
Pach, Radosław
Szura, Mirosław
Solecki, Rafał
Tomaszewski, Krzysztof A.
Szczepański, Wojciech
Matyja, Andrzej
Kulig, Jan
Powiązania:
https://bibliotekanauki.pl/articles/1395798.pdf
Data publikacji:
2014-07-01
Wydawca:
Index Copernicus International
Tematy:
adenocarcinoma
appendix
laparoscopic appendectomy
right hemicolectomy
Opis:
Primary adenocarcinoma of the vermiform appendix is a rare clinical condition. It usually presents as an acute abdominal process or as a mass in the right lower quadrant. The gross pathologic and microscopic characteristics of this disease are the same as for colon carcinoma and carry a serious prognosis. We report a case of a 64-year old male patient presenting symptoms of acute appendicitis. The patient underwent laparoscopic appendectomy that revealed a severely inflamed appendix. Histopathological examination has shown that it was a poorly differentiated, high grade adenocarcinoma invading the periappendicular fat. According to the histopathological findings, a right hemicolectomy was further advised and performed. Right hemicolectomy is the generally recommended method of treatment for invasive adenocarcinoma of the appendix
Źródło:
Polish Journal of Surgery; 2014, 86, 7; 333-336
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biochemistry of magnesium
Biochemia magnezu
Autorzy:
Pasternak, K
Kocot, J.
Horecka, A.
Powiązania:
https://bibliotekanauki.pl/articles/14627.pdf
Data publikacji:
2010
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Tematy:
magnesium
DNA repair process
enzyme
metabolic cycle
cellular respiration
calcium ion
ion transport
potassium ion
biochemistry
Opis:
Magnesium is essential for biochemical functions of cells. Since Mg2+ has a relatively low ionic radius in proportion to the size of the nucleus (0.86 versus 1.14 f A for Ca2+), it shows exceptional biochemical activity. Due to its physicochemical properties, intracellular magnesium can bind to the nucleus, ribosomes, cell membranes or macromolecules occurring in the cell’s cytosol. It is indispensable for the nucleus to function as a whole and for the maintenance of physical stability as well as aggregation of rybosomes into polysomes able to initiate protein synthesis. Mg2+ can also act as a cofactor for ribonucleic acid enzymes (ribozymes) capable of specifically recognizing and cleaving the target mRNA. As an essential cofactor in NER, BER, MMR processes, Mg2+ is required for the removal of DNA damage. An activator of over 300 different enzymes, magnesium participates in many metabolic processes, such as glycolysis, Krebs cycle, β-oxidation or ion transport across cell membranes. Mg2+ plays a key role in the regulation of functions of mitochondria, including the control of their volume, composition of ions and ATP production.
Magnez jest składnikiem niezbędnym dla zasadniczych funkcji biochemicznych komórki. Ponieważ Mg2+ ma relatywnie mały promień w stosunku do wymiarów jądra (0.86 i 1.14 A odpowiednio dla Mg2+ i Ca2+), wykazuje dużą aktywność biochemiczną. Dzięki właściwościom fizykochemicznym śródkomórkowy Mg2+ może wiązać się z jądrem komórkowym, rybosomami, błonami komórkowymi oraz makromolekułami cytosolu komórki. Magnez jest niezbędny dla funkcjonowania jądra komórkowego jako całości oraz utrzymania fizycznej stabilności i agregacji rybosomów do polisomów zdolnych do biosyntezy białka. Odgrywa on również rolą kofaktora katalitycznych cząsteczek RNA (rybozymów), odpowiedzialnych za specyficzne rozpoznawanie i fragmentację docelowego mRNA. Jako kofaktor w procesach: NER, BER, MMR, przyczynia się do usuwania uszkodzeń DNA. Magnez, będąc aktywatorem ponad 300 różnych enzymów, uczestniczy w przebiegu wielu szlaków metabolicznych, takich jak glikoliza, cykl Krebsa, β-oksydacja czy transport jonów poprzez błony komórkowe. Odgrywa on ponadto bardzo ważną rolę w regulowaniu funkcji mitochondriów, łącznie z regulacją ich wielkości, kompozycją jonów, a także bioenergetyką i regulacją produkcji ATP.
Źródło:
Journal of Elementology; 2010, 15, 3; 601-616
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bending of Orthotropic Plate Containing a Crack Parallel to the Median Plane
Autorzy:
Shvabyuk, V.
Pasternak, I.
Sulym, H.
Powiązania:
https://bibliotekanauki.pl/articles/386368.pdf
Data publikacji:
2011
Wydawca:
Politechnika Białostocka. Oficyna Wydawnicza Politechniki Białostockiej
Tematy:
zginanie
płyta ortotropowa
izotropia
anizotropia
bending
orthotropic plate
isotropic materials
anisotropy
Opis:
This paper considers cylindrical bending of the plate containing a crack parallel to plate's faces. The analytical model of the problem is obtained using the improved theory of plates bending, which considers transverse deformation of the plate. Received analytical results are compared with the numerical data of the boundary element approach, which is modified to suit the considered contact problem. The results of analytical and numerical techniques are in a good agreement both for the isotropic and anisotropic plates.
Źródło:
Acta Mechanica et Automatica; 2011, 5, 4; 94-102
1898-4088
2300-5319
Pojawia się w:
Acta Mechanica et Automatica
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 42

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