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    Wyświetlanie 1-11 z 11
    Tytuł:
    Branch and bound algorithm for discrete multi- level linear fractional programming problem
    Autorzy:
    Arora, R.
    Gupta, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/406478.pdf
    Data publikacji:
    2018
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    linear fractional programming problem
    bilevel programming
    multilevel programming
    discrete variables
    integer solution
    branch and bound cut
    programowanie dwustopniowe
    programowanie wielopoziomowe
    zmienne dyskretne
    Opis:
    An algorithm is proposed to find an integer solution for bilevel linear fractional programming problem with discrete variables. The method develops a cut that removes the integer solutions which are not bilevel feasible. The proposed method is extended from bilevel to multilevel linear fractional programming problems with discrete variables. The solution procedure for both the algorithms is elucidated in the paper.
    Źródło:
    Operations Research and Decisions; 2018, 28, 2; 5-21
    2081-8858
    2391-6060
    Pojawia się w:
    Operations Research and Decisions
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fuzzy goal programming technique for multi-objective indefinite quadratic bilevel programming problem
    Autorzy:
    Arora, R.
    Gupta, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/1403683.pdf
    Data publikacji:
    2020
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    bilevel programming
    indefinite quadratic programming
    multi-objective programming
    pay-off matrix
    Taylor series approximation
    LINGO 17.0
    Opis:
    Bilevel programming problem is a non-convex two stage decision making process in which the constraint region of upper level is determined by the lower level problem. In this paper, a multi-objective indefinite quadratic bilevel programming problem (MOIQBP) is presented. The defined problem (MOIQBP) has multi-objective functions at both the levels. The followers are independent at the lower level. A fuzzy goal programming methodology is employed which minimizes the sum of the negative deviational variables of both the levels to obtain highest membership value of each of the fuzzy goal. The membership function for the objective functions at each level is defined. As these membership functions are quadratic they are linearized by Taylor series approximation. The membership function for the decision variables at both levels is also determined. The individual optimal solution of objective functions at each level is used for formulating an integrated pay-off matrix. The aspiration levels for the decision makers are ascertained from this matrix. An algorithm is developed to obtain a compromise optimal solution for (MOIQBP). A numerical example is exhibited to evince the algorithm. The computing software LINGO 17.0 has been used for solving this problem.
    Źródło:
    Archives of Control Sciences; 2020, 30, 4; 683-699
    1230-2384
    Pojawia się w:
    Archives of Control Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    QSAR modeling for acute toxicity prediction in rat by common painkiller drugs
    Autorzy:
    Roy, J.S.
    Gupta, K.
    Talapatra, S.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/11550.pdf
    Data publikacji:
    2016
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Opis:
    Painkiller drugs or analgesics are potent pain reliever chemical agents, which are commonly used in pain therapy. Mathematical modeling by QSAR (quantitative structure activity relationship) methods are well known practices to determine predictive toxicity in biota. Now-adays, an easy screening of chemicals, QSAR can be done by using several recommended softwares. The present study was carried out by using software namely T.E.S.T. (Toxicity estimation software tool) for rat oral LD50 (median lethal dose) predictive toxicity for common painkiller drugs. These painkiller drugs were selected as 35 compounds and tabulated on the basis characteristics of one non-narcotic viz. acetaminophen, twenty non-steroidal anti-inflammatory such as bromofenac, diclofenac, diflunsial, etodolac, fenoprofen, flurbiprofen, ibuprofen, indomethacin, ketoprofen, ketorolac, maclofenamate sodium, mefenamic acid, meloxicam, nabumetone, naproxen, oxaprozin, phenylbutazone, piroxicam, sulindac and tolmetin as well as fourteen narcotic viz. buprenorphine, butorphanol, codeine, hydrocodone, hydromorphone, levorphanol, meperidine, methadone, morphine, nalbuphine, oxycodone, pentazocine, dextropropoxyphene and tapentadol. The data were tabulated on experimental (bioassay) from ChemIDPlus and T.E.S.T. and predictive toxicity of 30 compounds out of 35 compounds by using T.E.S.T. The predictive data were found by T.E.S.T. that 20 and 10 compounds were very toxic and moderately toxic respectively but not extremely, super toxic and non-toxic in rat model after acute oral exposure. It is suggested to evaluate the predicted data further with other available recommended softwares with different test models like daphnia, fish etc. to know aquatic toxicity when these compounds may discharge into waterbodies.
    Źródło:
    International Letters of Natural Sciences; 2016, 52
    2300-9675
    Pojawia się w:
    International Letters of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Using Web Services to enhance Geographic Information Systems
    Autorzy:
    Ladner, R.
    Petry, F.
    Warner, E.
    Gupta, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/970472.pdf
    Data publikacji:
    2006
    Wydawca:
    Polska Akademia Nauk. Instytut Badań Systemowych PAN
    Tematy:
    ontologia
    usługa WWW
    dane przestrzenne
    system informacji przestrzennej
    ontology
    web services
    spatial data
    GIS
    geographic information systems
    Opis:
    In this paper we describe an approach to the extension of geographic information systems to take advantage of the continuing development of capabilities of the Semantic Web. This is presented in the context of a portal based Geospatial Information Database (GIDB™), an object-oriented spatial database capable of storing multiple data types from multiple sources. We have developed our approach for a specific domain, spatially oriented, meteorological and oceanographic, but this can clearly be applied to other Spatial data domains. Finally we illustrate the use of the ontology development system based on Generative Sublanguage Ontologies (GSO), a type of linguistic ontology inspired by the Generative Lexicon Theory, to develop effective domain ontologies.
    Źródło:
    Control and Cybernetics; 2006, 35, 1; 29-46
    0324-8569
    Pojawia się w:
    Control and Cybernetics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    To predict human Biomarker for the obesity using mouse homologous expression data at different theiler stages
    Autorzy:
    Kumar, A.
    Puri, R.
    Gupta, K.
    Pal, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/11371.pdf
    Data publikacji:
    2015
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Opis:
    There are numerous genetic factors like MC4R (Melanocortin-4 receptor), POMC (Proopiomelanocortin), SIM1 (Single Minded Gene) etc. important in obesity, which can be used as biomarker. But more reliable diagnostic markers are the need for today, along with new therapeutic strategies that target specific molecules in the disease pathways. As in mouse and human genes, where mutations in one or both species are associated with some phenotypic characteristics as observed in human disease. In molecular mechanisms of development, differentiation, and disease gene expression data provide crucial insights. Up-regulation and down-regulation of selective genes can have major effects on diet-induced obesity, but there is little or no effect when animals are fed a low-fat diet. In present study we have studied the gene expression data of mouse at different theiler stages using GXD BioMart. The interacting partners and pathway of the genes that are already used as biomarker in mouse as well as in humans have been studied. A gene NPY1R (Neuropeptide Y1 receptor) was taken as common after STRING and KEGG results on the basis of biochemical pathways and interactions similar to MC4R. Our present work focuses on comparative genomics and proteomics analysis of NPY1R, which has led to identification of biomarker by comparing it with already known MC4R human and mouse biomarker. It has been concluded that both the proteins are structurally and functionally similar.
    Źródło:
    International Letters of Natural Sciences; 2015, 45
    2300-9675
    Pojawia się w:
    International Letters of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Text mining approach to analyse the relation between obesity and breast cancer data
    Autorzy:
    Kumar, A.
    Thakur, P.
    Gupta, K.
    Pal, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/10908.pdf
    Data publikacji:
    2015
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Opis:
    Biomedical research needs to leverage and exploit large amount of information reported in scientific publication. Literature data collected from publications has to be managed to extract information, transforms into an understandable structure using text mining approaches. Text mining refers to the process of deriving high-quality information from text by finding relationships between entities which do not show direct associations. Therefore, as an example of this approach, we present the link between two diseases i.e. breast cancer and obesity.Obesity is known to be associated with cancer mortality, but little is known about the link between lifetime changes in BMI of obese person and cancer mortality in both males and females. In this article, literature data for obesity and breast cancer was obtained using PubMed database and then methodologies which employs groups of common genes and keywords with their frequency of occurrence in the data were used, aimed to establish relation between obesity and breast cancer visualized using Pi-charts and bar graphs. From the data analysis, we obtained 1 gene which showed the link between both the diseases and validated using statistical analysis and disease-connect web server. We also proposed 8 common higher frequency keywords which could be used for indexing while searching the literature for obesity and breast cancer in combination.
    Źródło:
    International Letters of Natural Sciences; 2015, 44
    2300-9675
    Pojawia się w:
    International Letters of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Biomonitoring of river Ganga bank by identifying mollusc species as an indicator
    Autorzy:
    Gupta, K.
    Nandy, A.
    Banerjee, K.
    Talapatra, S.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/10869.pdf
    Data publikacji:
    2015
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Opis:
    The present study deals with biomonitoring to know mollusc species as an indicator. In the present study, presence, absence and abundance of particular gastropod and bivalve species were identified in the different banks of river Ganga. The study was carried out at two experimental sites, Sodepur (Exp-1) and Khardah (Exp-2), West Bengal, India as the area exhibits a major sewage water outfall in the river compared with upstream control site, Kalyani (Cont-1) and downstream control site, Batanagar (Cont-1). The present biomonitoring shows qualitatively and quantitatively that in experimental no mollusc species were observed near the wastewater discharge area into the bank of river Ganga at Khardah while both sites of the sewage discharge area into the bank of river Ganga at Sodepur particular gastropod Bellamya sp. were observed when compared to control area. The highest variety and total nos of gastropods and bivalves (280 nos) were recorded in the upstream at Kalyani and lowest variety and total nos of only gastropods (150 nos) were recorded in the downstream at Batanagar. The present biomonitoring work was a preliminary observation to know sensitive and tolerant or accumulator mollusc species in the bank of river Ganga from a stretch of Kalyani (upstream) to Batanagar (downstream) in between urban wastewater discharge area (Sodepur and Khardah). Further researches must be relevant in relation to biomarker assessment with the physico-chemical factors and stress tolerant detoxification mechanism of particular mollusc species.
    Źródło:
    International Letters of Natural Sciences; 2015, 37
    2300-9675
    Pojawia się w:
    International Letters of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Biomonitoring tool: morphological anomalies in Zygnema sp. of Ganga River Bank
    Autorzy:
    Das, K.
    Gupta, K.
    Swarnakar, S.
    Talapatra, S.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/11639.pdf
    Data publikacji:
    2015
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Opis:
    The present study aims to detect morphological abnormalities in Zygnema sp. because this test species have high adaptive capacity in unfavourable environmental stress. This alga is inhabited at the suburban bank of river Ganga, West Bengal, India. The study was done at experimental sites, downstream at Khardah near sewage water mixing area was compared with upstream control site Kalyani as no sewage water discharge. External and internal abnormal morphology such as undulating or wavy and extra outgrowth on cell wall, sometimes bending inwardly and outwardly as external deformities while internal anomalies such as pigment loss, nucleus was in circular, rectangular, oval and amoeboid shapes, also vacuolated and trilobed, broom like chloroplasts and central part of the thallas dried in between two segments. It was observed that this test species was surviving and well adapted with above mentioned deformities. The present preliminary study with Zygnema sp. can be utilized for in situ and ex situ indicator species for riverine biomonitoring. Further research may be relevant to know both tolerant and sensitive algae species inhabited at the river Ganga bank alongwith biochemical and genetic parameters. The present work is suggesting that other inhabiting algae and this adaptive test species can be used for bioremediation of pollutants.
    Źródło:
    International Letters of Natural Sciences; 2015, 47
    2300-9675
    Pojawia się w:
    International Letters of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    New insights into functional roles of nitric oxide in roots
    Autorzy:
    Gupta, K.
    Igamberdiev, A.
    Kruger, N.
    Kaiser, W.
    Ratcliffe, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/80596.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    conference
    nitric oxide
    nitrate reductase
    electron transport chain
    mitochondrion
    root
    proton pumping
    alternative oxidase
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The role of alternative oxidase in hypoxic metabolism of nitric oxide
    Autorzy:
    Igamberdiev, A.
    Shah, J.
    Cochrane, D.
    Gupta, K.
    Vanlerberghe, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/81011.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    conference
    alternative oxidase
    cytochrome C oxidase
    nitric oxide
    metabolism
    hypoxia
    gene expression
    oxygen condition
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Trend of arsenic pollution and subsequent bioaccumulation in Oryza sativa and Corchorus capsularis in Bengal Delta
    Autorzy:
    Bhattacharya, S.
    Guha, G.
    Gupta, K.
    Chattopadhyay, D.
    Mukhopadhyay, A.
    Ghosh, U.C.
    Powiązania:
    https://bibliotekanauki.pl/articles/10831.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    trend
    arsenic pollution
    bioaccumulation
    rice
    Oryza sativa
    jute
    Corchorus capsularis
    Bengal Delta zob.Ganges Delta
    Ganges River
    Ganges Delta
    Opis:
    Oryza sativa Linn. (rice) and Corchorus capsularis Linn. (jute) are the two major crops of the Bengal basin. Both rice and jute are generally grown in submerged flooded conditions, where arsenic bioavailability is high in soil. The consumers of the edible parts from both plants therefore face an inevitable source of exposure to arsenic, with consequent accumulation and toxicity. The objective of the study was to observe the in-vivo temporal variation of arsenic bioaccumulation in the different parts of O. sativa and C. capsularis. Rice plant specimens (Aman rice, Ratna variety) of different age groups (1, 2 and 3 months old) were analyzed in HG-AAS for absorbed arsenic content in different parts. The accumulation of arsenic remained significantly high in the initial phase of growth, but decreased with time. Amount of arsenic bioaccumulation followed the decreasing order: root > basal stem > median stem > apical stem > leaves > grains in all the three age groups of the rice plant samples. C. capsularis followed a trend of arsenic bioaccumulation similar to O. sativa. O. sativa had more accumulation potential than C. capsularis, but C. capsularis showed much higher efficiency of arsenic translocation in the above ground parts. This is the first ever report of time-dependent decrease in arsenic bioaccumulation in O. sativa and C. capsularis. The contamination level can reach the grain part in significant amount and can cause health hazards in more severely arsenic affected areas. Intensive investigation on a complete food chain is urgently needed in the arsenic contaminated zones for further risk assessments.
    Źródło:
    International Letters of Natural Sciences; 2014, 16
    2300-9675
    Pojawia się w:
    International Letters of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-11 z 11

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