- Tytuł:
- Asymmetry in nucleotide composition of sense and antisense strands as a parameter for discriminating open reading frames as protein coding sequences
- Autorzy:
-
Cebrat, S
Dudek, M R
Rogowska, A - Powiązania:
- https://bibliotekanauki.pl/articles/2046596.pdf
- Data publikacji:
- 1997
- Wydawca:
- Polska Akademia Nauk. Czytelnia Czasopism PAN
- Tematy:
-
concentration ellipse
yeast chromosome
DNA asymmetry
coding function
open reading frame
nucleotide composition
Saccharomyces cerevisiae - Opis:
- Coding properties of yeast chromosomes were analysed and a strong asymmetry was found in nucleotide composition of sense and antisense strands. This property generates two very simple parameters - [A]/[T] and [G]/[C] of the sense strand - which could be used for discrimination of open reading frames as coding sequences with very high, statistically described level of significance. The paper contains a description of the method of ellipse of concentration in the two parameter space, which can close coding sequences inside, leaving a big fraction of noncoding sequences outside the ellipse.
- Źródło:
-
Journal of Applied Genetics; 1997, 38, 1; 1-9
1234-1983 - Pojawia się w:
- Journal of Applied Genetics
- Dostawca treści:
- Biblioteka Nauki
Artykuł