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Wyświetlanie 1-2 z 2
Tytuł:
Determinants of premature mortality in a city population: An eight-year observational study concerning subjects aged 18–64
Autorzy:
Maniecka-Bryła, Irena
Dziankowska-Zaborszczyk, Elżbieta
Bryła, Marek
Drygas, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/2179076.pdf
Data publikacji:
2013-10-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
premature mortality
survival analysis
cox proportional hazards model
Polska
Opis:
Background: Premature deaths constitute 31.1% of all deaths in Łódź. Analysis of the causes of premature deaths may be helpful in the evaluation of health risk factors. Moreover, findings of this study may enhance prophylactic measures. Material and Methods: In 2001, 1857 randomly selected citizens, aged 18-64, were included in the Countrywide Integrated Noncommunicable Diseases Intervention (CINDI) Programme. In 2009, a follow-up study was conducted and information on the subjects of the study was collected concerning their health status and if they continued to live in Łódź. The Cox proportional hazards model was used for evaluation of hazard coefficients. We adjusted our calculations for age and sex. The analysis revealed statistically significant associations between the number of premature deaths of the citizens of Łódź and the following variables: a negative self-evaluation of health - HR = 3.096 (95% CI: 1.729-5.543), poor financial situation - HR = 2.811 (95% CI: 1.183‑6.672), occurring in the year preceding the study: coronary pain - HR = 2.754 (95% CI: 1.167-6.494), depression - HR = 2.001 (95% CI: 1.222-3.277) and insomnia - HR = 1.660 (95% CI: 1.029-2.678). Our research study also found a negative influence of smoking on the health status - HR = 2.782 (95% CI: 1.581-4.891). Moreover, we conducted survival analyses according to sex and age with Kaplan-Meier curves. Conclusions: The risk factors leading to premature deaths were found to be highly significant but possible to reduce by modifying lifestyle-related health behaviours. The confirmed determinants of premature mortality indicate a need to spread and intensify prophylactic activities in Poland, which is a post-communist country, in particular, in the field of cardiovascular diseases.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2013, 26, 5; 724-741
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Extensions of cox model for non-proportional hazards purpose
Autorzy:
Borucka, Jadwiga
Powiązania:
https://bibliotekanauki.pl/articles/425219.pdf
Data publikacji:
2014
Wydawca:
Wydawnictwo Uniwersytetu Ekonomicznego we Wrocławiu
Tematy:
Cox model
survival analysis
non-proportional hazards
Opis:
Cox proportional hazard model is one of the most common methods used in time to event analysis. The idea of the model is to define a hazard level as a dependent variable which is explained by the time-related component (so-called baseline hazard) and the covariates- related component. The model is based on several restrictive assumptions one of which is the assumption of proportional hazard. However, if this assumption is violated, this does not necessarily prevent an analyst from using Cox model. The current paper presents two ways of model modification in the case of non-proportional hazards: introducing interactions of selected covariates with function of time and stratification model. Calculations performed give the evidence that both methods result in better model fit as compared with the original model. Additionally, they allow interpreting the parameters estimates more precisely, taking into account the effect of the covariate at the hazard level that is changing over time. The choice of the appropriate method of tied events handling however is not straightforward and should be adjusted to the particular analysis purpose.
Źródło:
Econometrics. Ekonometria. Advances in Applied Data Analytics; 2014, 3(45); 85-101
1507-3866
Pojawia się w:
Econometrics. Ekonometria. Advances in Applied Data Analytics
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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