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Wyświetlanie 1-12 z 12
Tytuł:
Niektore parametry odpornosci u pacjentow z rzesistkowica jamy ustnej powiklanej grzybica [trichomonosomycosis]
Autorzy:
Kurnatowska, A J
Kurnatowska, P.
Powiązania:
https://bibliotekanauki.pl/articles/841239.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
odpornosc czlowieka
Trichomonas tenax
czynniki chorobotworcze
Candida
rzesistek policzkowy
parazytologia lekarska
odpornosc humoralna
choroby grzybowe
pasozyty
odpornosc komorkowa
rzesistkowica
grzybice
Opis:
The objective of the study was the analysis of selected parameters of humoral and cellular immunity in patients with Trichomonas tenax and fungi existing concurrently in the oral cavity ontocenosis. The study included 37 patients (age range 26-70 years, x=54.5±4.l) diagnosed with trichomonosomycosis. Standard methods were used to determine the total level of protein and its individual fractions, leukocytosis and sedimentation rate. Serum levels of immunoglobulins IgA, IgM and IgG, and the level of IgA immunoglobulin in saliva (S-IgA) were determined with the immunodilTussion method using NOR-Partigen and LC-Partigen (Behring) platelets. To define blastic and miotic indices (IB and IM), rosette tests ER, EAR and EACR as well as phytohemagglutinin-induced (PHA) blastic transformation test were employed. In 21.1% of patients, a decrease in total protein level (on the average 6.85±0.23 g/dl), and in 11.1% in globulins of y fraction (18.5±1.18%) was observed, in 40% of cases the leukocytes count was higher (10080±690.7), and in all patients the sedimentation rate was accelerated (77.9±12.2 mm). The level of class A immunoglobulins (368.7±49,0 mg%) was in 29.2% above norm, and of IgG class (1182.8±92.9 mg%) was in 13.6% below norm and in 13.6% above norm. In case of S-IgA (8.15±0.63 mg%), the level was below norm in all patients. Also in all patients a decreased lymphocytes T count (value ER - 37.3±1.04%) and deficiency in their function (indices: IB 22.5±2.98%, IM 2.3±0.84%) could be observed, whereas lymphocytes B count was increased (values EAR - 18.3±0.7%; values EACR -22.1-0.77). These data indicate that in cases of oral trichmonosomycosis there occurs a low level of secretory immunoglobulin class A in saliva and the number of lymphocytes T, deficient in function, is decreased.
Źródło:
Annals of Parasitology; 1998, 44, 1; 41-45
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Niektóre parametry odporności u pacjentów z rzęsistkowicą jamy ustnej powikłanej grzybicą [trichomonosomycosis]
SELECTED PARAMETERS OF IMMUNITY IN PATIENTS WITH ORAL TRICHOMONOSIS COMPLICATED BY MYCOSIS (TRICHOMONOSOMYCOSIS)
Autorzy:
Kurnatowska, A. J.
Kurnatowska, P.
Powiązania:
https://bibliotekanauki.pl/articles/2148843.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
odpornosc czlowieka
Trichomonas tenax
czynniki chorobotworcze
Candida
rzesistek policzkowy
parazytologia lekarska
odpornosc humoralna
choroby grzybowe
pasozyty
odpornosc komorkowa
rzesistkowica
grzybice
Opis:
The objective of the study was the analysis of selected parameters of humoral and cellular immunity in patients with Trichomonas tenax and fungi existing concurrently in the oral cavity ontocenosis. The study included 37 patients (age range 26-70 years, x=54.5±4.l) diagnosed with trichomonosomycosis. Standard methods were used to determine the total level of protein and its individual fractions, leukocytosis and sedimentation rate. Serum levels of immunoglobulins IgA, IgM and IgG, and the level of IgA immunoglobulin in saliva (S-IgA) were determined with the immunodilTussion method using NOR-Partigen and LC-Partigen (Behring) platelets. To define blastic and miotic indices (IB and IM), rosette tests ER, EAR and EACR as well as phytohemagglutinin-induced (PHA) blastic transformation test were employed. In 21.1% of patients, a decrease in total protein level (on the average 6.85±0.23 g/dl), and in 11.1% in globulins of y fraction (18.5±1.18%) was observed, in 40% of cases the leukocytes count was higher (10080±690.7), and in all patients the sedimentation rate was accelerated (77.9±12.2 mm). The level of class A immunoglobulins (368.7±49,0 mg%) was in 29.2% above norm, and of IgG class (1182.8±92.9 mg%) was in 13.6% below norm and in 13.6% above norm. In case of S-IgA (8.15±0.63 mg%), the level was below norm in all patients. Also in all patients a decreased lymphocytes T count (value ER - 37.3±1.04%) and deficiency in their function (indices: IB 22.5±2.98%, IM 2.3±0.84%) could be observed, whereas lymphocytes B count was increased (values EAR - 18.3±0.7%; values EACR -22.1-0.77). These data indicate that in cases of oral trichmonosomycosis there occurs a low level of secretory immunoglobulin class A in saliva and the number of lymphocytes T, deficient in function, is decreased.
Źródło:
Wiadomości Parazytologiczne; 1998, 44, 1; 41-45
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Inwazja Trichomonas tenax u pacjentow z chorobami przyzebia
Autorzy:
Kurnatowska, A.J.
Dudko, A.
Kurnatowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/836163.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Trichomonas tenax
rzesistek policzkowy
parazytologia lekarska
pacjenci
choroby przyzebia
inwazja pasozytnicza
Źródło:
Annals of Parasitology; 2004, 50, 3; 397-403
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Inwazja Trichomonas tenax u pacjentów z chorobami przyzębia
Invasion of Trichomonas tenax in patients with periodontal diseases
Autorzy:
Kurnatowska, A.J.
Dudko, A.
Kurnatowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/2147379.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Trichomonas tenax
rzesistek policzkowy
parazytologia lekarska
pacjenci
choroby przyzebia
inwazja pasozytnicza
Opis:
The aim of the study was to analyze the frequency of occurrence of Trichomonas tenax in patients with periodontitis and also to check the relationship between the occurrence of the protozoan and the indices of oral hygiene, and to evaluate periodontal treatment needs. The study involved 91 individuals aged 23-79 years (52 women and 39 men). 34 of them were infected with Trichomonas tenax. The study revealed dependence between the frequency of occurrence of Trichomonas tenax and the state of periodontium and the hygiene of the oral cavity.
Źródło:
Wiadomości Parazytologiczne; 2004, 50, 3; 397-403
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena aktywnosci kwasnej proteazy asparaginowej szczepow Candida wyizolowanych z jamy ustnej u pacjentow z podwyzszonym ryzykiem zakazenia grzybami
Autorzy:
Rozga, A
Kurnatowska, A.J.
Raczynska-Witonska, G.
Loga, G.
Powiązania:
https://bibliotekanauki.pl/articles/841502.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
nowotwory
aktywnosc proteolityczna
choroby czlowieka
rak krtani
aktywnosc enzymatyczna
Candida
parazytologia lekarska
pacjenci
kwasna proteaza asparaginowa
wymazy z jamy ustnej
szczepy grzybow
zaburzenia immunologiczne
Opis:
We have evaluated the activity of acid aspartic protease in 195 strains of Candida isolated from the oral cavity of three groups of patients. The first group comprised patients with cancer of the larynx qualified for surgery, the second- patients with neoplastic disease (Hodgkin's disease, lymphoma, acute granulocytic leukaemia, lymphatic leukaemia, lung cancer, multiple myeloma, stomach cancer, breast cancer) who were not treated, the third group- patients with neoplastic diseases treated by chemotherapy. The strains of fungi were differentiated using API 20C and Api 20C AUX tests according to the protocol adopted at the Department of Medical Parasitology and Biology, Medical University of Łódż. The activity of acid protease was studied by Staib method in Rózga modification. Almost all strains showed high and very high proteolytic activity. The rang of proteolysis zone of Candida strains from the three groups of patients varied from 2,5 to 12,5 mm. We have found the mean proteolytic zones of strains isolated from groups Iand III differed statistically significantly (p<0,001). Similarly, statisticall sihnificant difference was seen between these parameters for groups II and III (p<0,05), while there was no difference between strains from group I and II.
Źródło:
Annals of Parasitology; 2001, 47, 4; 883-890
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena aktywności kwaśnej proteazy asparaginowej szczepów Candida wyizolowanych z jamy ustnej u pacjentów z podwyższonym ryzykiem zakażenia grzybami
EVALUTION OF ACTIVITY OF ACID ASPARTIC PROTEINASE IN CANDIDA STRAINS . ISOLATED FROM ORAL CAVITY OF PATIENTS WITH INCREASED RISK OF MYCOSIS
Autorzy:
Rózga, A.
Kurnatowska, A.J.
Raczyńska-Witońska, G.
Loga, G.
Powiązania:
https://bibliotekanauki.pl/articles/2148245.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
nowotwory
aktywnosc proteolityczna
choroby czlowieka
rak krtani
aktywnosc enzymatyczna
Candida
parazytologia lekarska
pacjenci
kwasna proteaza asparaginowa
wymazy z jamy ustnej
szczepy grzybow
zaburzenia immunologiczne
Opis:
We have evaluated the activity of acid aspartic protease in 195 strains of Candida isolated from the oral cavity of three groups of patients. The first group comprised patients with cancer of the larynx qualified for surgery, the second- patients with neoplastic disease (Hodgkin's disease, lymphoma, acute granulocytic leukaemia, lymphatic leukaemia, lung cancer, multiple myeloma, stomach cancer, breast cancer) who were not treated, the third group- patients with neoplastic diseases treated by chemotherapy. The strains of fungi were differentiated using API 20C and Api 20C AUX tests according to the protocol adopted at the Department of Medical Parasitology and Biology, Medical University of Łódż. The activity of acid protease was studied by Staib method in Rózga modification. Almost all strains showed high and very high proteolytic activity. The rang of proteolysis zone of Candida strains from the three groups of patients varied from 2,5 to 12,5 mm. We have found the mean proteolytic zones of strains isolated from groups Iand III differed statistically significantly (p<0,001). Similarly, statisticall sihnificant difference was seen between these parameters for groups II and III (p<0,05), while there was no difference between strains from group I and II.
Źródło:
Wiadomości Parazytologiczne; 2001, 47, 4; 883-890
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrazliwosc na mikonazol i itrakonazol szczepow grzybow z rodzaju Candida wyodrebnionych od pacjentow hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:
Kurnatowska, A.K.
Kwasniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/840111.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Źródło:
Annals of Parasitology; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrażliwość na mikonazol i itrakonazol szczepów grzybów z rodzaju Candida wyodrębnionych od pacjentów hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:
Kurnatowska, A.K.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2143561.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Opis:
It is known that fungi representing different genera and species can cause organ-limited or systemic infections after disrupting of the natural defense mechanisms in a human organism. The treatment of mycoses still encounters considerable difficulties. Therefore, in vitro assessment of the susceptibility of fungal strains to the antifungal agents now in use and to new drugs is needed more urgently than ever before. It should be emphasized that we treat the fungal susceptibility to antifungal drugs as a quantitative feature of the strain examined. The aim of the presently reported study was the evaluation of the antimycotic action of two azole compounds – miconazole and itraconazole (Janssen) against 205 Candida strains isolated from the various biological specimens of two groups of patients – hospitalized (group 1) and examined in outpatient clinic (group 2); differentiation of species and codes of these strains; analysis of dose-response curves and parameters of polygons of the azoles minimal inhibitory concentrations (MIC). The susceptibility to miconazole and itraconazole was estimated with the agar diffusion test on 3% Sabouraud’s agar – the method developed in our laboratory, using several different concentrations of the drug, which made the plotting of dose-response curves possible. The lowest concentration inhibiting the growth of fungal strain (MIC) was calculated using a transformed equation of rectilinear regression according to Kadłubowski. Species and fungal codes of isolated strains were evaluated according to the guidelines worked out in our department with the use of different media and biochemical tests (bioMérieux). Among 89 strains isolated from the hospitalized patients, six species of the genus Candida genus were found; one strain belonged to Trichosporon cutaneum species. The most frequently encountered species was Candida albicans (73%), which significantly dominated over C. tropicalis, C. parapsilosis, C. glabrata, C. lipolytica and C. famata. All strains from the second group of patients belonged to C. albicans species. In all C. albicans strains from both groups of patients, the most frequent assimilation code (2576174) was found. The miconazole MIC values for Candida strains isolated from the group 1 were characterized by a wide range of variation, from 0.0247mg/l to 6.826 mg/l, from group 2 – 0.0277 to 0.719 mg/l. The itraconazole MIC values were 0.011 to 2.813 mg/l, and 0.0103 to 0.718 mg/l, respectively. The analysis of mean values (x) of miconazole and itraconazole MICs and other parameters allowed us to find that the strains isolated from the patients of group 1 were significantly less susceptible to both drugs in comparison with the strains of the group 2 patients. Also, C. albicans strains from this group of patients had a significantly lower (x) MIC in comparison to the mean values for the most of Candida species isolated from the hospitalized patients (P<0.001). In conclusion, we have found that the most Candida strains from both groups of patients were susceptible to the examined antifungal agents. The strains isolated from the outpatient clinic patients were generally more susceptible especially to itraconazole in comparison with strains from hospitalized patients.
Źródło:
Wiadomości Parazytologiczne; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zwiazek miedzy aktywnoscia hydrolaz grzybow wyizolowanych z pochwy kobiet ciezarnych i wybranymi objawami klinicznymi
Autorzy:
Nowakowska, D
Kurnatowska, A.
Wilczynski, J.
Powiązania:
https://bibliotekanauki.pl/articles/839878.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
pochwa
grzyby
objawy kliniczne
zakazenia grzybicze
aktywnosc enzymatyczna
hydrolazy
parazytologia lekarska
kobiety ciezarne
izolaty grzybowe
Opis:
Relationship between activity of hydrolases in fungi isolated from vagina of pregnant women and selected symptoms. Pregnancy is considered a factor of vulvovaginal mycosis. Secretion of hydrolases is an important determinant of Candida virulence. Thus, the aim of the study was to found the relationsbip between activity of 19 hydrolases in fungi isolated from vagina of pregnant women and symptoms of mycosis. 251 pregnant women were examined. Samples were collected from vagina and cultured on Sabouraud media. Activity of hydrolytic enzymes was evaluated using API ZYM (bioMerieux) test. Fungi were found in 20.1% of vaginal samples. Symptoms were detected in 45.8% of wornen. Only 32.1% of women with discharge and 26.4% with pruritus had mycosis. Out of the 19 examined hydrolazes, 13 active enzymes were detected in fungal strains. We found for the first time the relationsbip between activity of fungal esterase lipase and the presence of vaginal discharge in pregnant women.
Źródło:
Annals of Parasitology; 2002, 48, 3; 263-269
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Związek między aktywnością hydrolaz grzybów wyizolowanych z pochwy kobiet ciężarnych i wybranymi objawami klinicznymi
Autorzy:
Nowakowska, D.
Kurnatowska, A.
Wilczyński, J.
Powiązania:
https://bibliotekanauki.pl/articles/2147710.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
pochwa
grzyby
objawy kliniczne
zakazenia grzybicze
aktywnosc enzymatyczna
hydrolazy
parazytologia lekarska
kobiety ciezarne
izolaty grzybowe
Opis:
Relationship between activity of hydrolases in fungi isolated from vagina of pregnant women and selected symptoms. Pregnancy is considered a factor of vulvovaginal mycosis. Secretion of hydrolases is an important determinant of Candida virulence. Thus, the aim of the study was to found the relationsbip between activity of 19 hydrolases in fungi isolated from vagina of pregnant women and symptoms of mycosis. 251 pregnant women were examined. Samples were collected from vagina and cultured on Sabouraud media. Activity of hydrolytic enzymes was evaluated using API ZYM (bioMerieux) test. Fungi were found in 20.1% of vaginal samples. Symptoms were detected in 45.8% of wornen. Only 32.1% of women with discharge and 26.4% with pruritus had mycosis. Out of the 19 examined hydrolazes, 13 active enzymes were detected in fungal strains. We found for the first time the relationsbip between activity of fungal esterase lipase and the presence of vaginal discharge in pregnant women.
Źródło:
Wiadomości Parazytologiczne; 2002, 48, 3; 263-269
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Właściwości przeciwrzęsistkowe pochodnych eterów zawierających reszty aminowe i chlorowcoaryloalkilowe
Trichomonacidal properties of the derivatives of ethers containing amine and halogenaryloalkyl groups
Autorzy:
Białasiewicz, D.
Kotełko, B.
Kurnatowska, A.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2152441.pdf
Data publikacji:
1990
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parazytologia lekarska
rzesistek pochwowy
Trichomonas vaginalis
srodki lecznicze
pochodne eterow
reszty aminowe
reszty chlorowcoaryloalkilowe
substancje biologicznie czynne
zwiazki organiczne
dzialanie przeciwpasozytnicze
aktywnosc rzesistkobojcza
Opis:
The trichomonacidal activity in vitro of 6 new derivatives of theirs containing amine and halogenaryloalkyl groups in comparison with metronidazole, ornidazole and tinidazole has been examined. For all the examined compounds curves of action were obtained after 30 min. and lethal concentrations for 50% population (CL₅₀) of three strains of T. vaginalis used for experiments were calculated. The trichomonacidal action of the following compounds was especialy strong: 2-/1-methylpiperazin-4-yl/ethyl-4-chlorbenzhydryl ether dihydrochloride and 2-/1-benzylperhydro-1,4-diazepin-4-yl/ethyl 2,4-dichlorbenzyl ether dihydrochloride. The trichomonacidal action of these compounds was several times stronger than that of metronidazole and tinidazole.
Źródło:
Wiadomości Parazytologiczne; 1990, 36, 5-6; 281-285
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Właściwości przeciwrzęsistkowe pochodnych eterów zawierających reszty aminowe i chlorowcoaryloalkilowe
Trichomonacidal properties of the derivatives of ethers containing amine and halogenaryloalkyl groups
Autorzy:
Bialasiewicz, D.
Kotelko, B.
Kurnatowska, A.
Kwasniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/836304.pdf
Data publikacji:
1990
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parazytologia lekarska
rzesistek pochwowy
Trichomonas vaginalis
srodki lecznicze
pochodne eterow
reszty aminowe
reszty chlorowcoaryloalkilowe
substancje biologicznie czynne
zwiazki organiczne
dzialanie przeciwpasozytnicze
aktywnosc rzesistkobojcza
Opis:
The trichomonacidal activity in vitro of 6 new derivatives of theirs containing amine and halogenaryloalkyl groups in comparison with metronidazole, ornidazole and tinidazole has been examined. For all the examined compounds curves of action were obtained after 30 min. and lethal concentrations for 50% population (CL₅₀) of three strains of T. vaginalis used for experiments were calculated. The trichomonacidal action of the following compounds was especialy strong: 2-/1-methylpiperazin-4-yl/ethyl-4-chlorbenzhydryl ether dihydrochloride and 2-/1-benzylperhydro-1,4-diazepin-4-yl/ethyl 2,4-dichlorbenzyl ether dihydrochloride. The trichomonacidal action of these compounds was several times stronger than that of metronidazole and tinidazole.
Źródło:
Annals of Parasitology; 1990, 36, 5-6
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-12 z 12

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