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Wyświetlanie 1-14 z 14
Tytuł:
Wrazliwosc na ketokonazol szczepow Candida zasiedlajacych ontocenozy przewodu pokarmowego dzieci
Autorzy:
Horwatt-Bozyczko, E
Kurnatowski, M.
Wasowska-Krolikowska, K.
Kurnatowska, A.
Powiązania:
https://bibliotekanauki.pl/articles/836934.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
zasiedlanie
ontocenozy
ketokonazol
grzyby
przewod pokarmowy
Candida
parazytologia lekarska
dzieci
wrazliwosc na antybiotyki
szczepy grzybow
Opis:
The study included 52 children. During endoscopy the contents of oesophagus, stomach and duodenum were collected with catheters, and additionally washings from the oral cavity and anal swabs or samples of faeces. Materials were inoculated on Sabouraud's media. The axenic strains of fungi were identified using own methods and others tests (API 20C, API 20C AUX). The activity of ketoconazole (K) was measured against 100 strains of Candida: C. albicans (91 strains), C. kefyr (4), C. famata (2). C. tropicalis (1), C. guilliermondii (1), C. glabrata (1). The strains susceptibility to K (RO4 1400 Janssen) was estimated with the own system based on the dose - response curves; the minimal inhibitory concentration (MIC) values were canculated. The low values of MIC indicate high susceptibility to K of examined Candida strains.
Źródło:
Annals of Parasitology; 2001, 47, 4; 929-933
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrażliwość na ketokonazol szczepów Candida zasiedlających ontocenozy przewodu pokarmowego dzieci
THE SUSCEPTIBILITY TO KETOCONAZOLE OF CANDIDA STRAINS ISOLATED FROM THE DIGESTIVE TRACT ONTOCENOSES IN CHILDREN*
Autorzy:
Horwatt-Bożyczko, E.
Kurnatowski, M.
Wąsowska-Królikowska, K.
Kurnatowska, A.
Powiązania:
https://bibliotekanauki.pl/articles/2148254.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
zasiedlanie
ontocenozy
ketokonazol
grzyby
przewod pokarmowy
Candida
parazytologia lekarska
dzieci
wrazliwosc na antybiotyki
szczepy grzybow
Opis:
The study included 52 children. During endoscopy the contents of oesophagus, stomach and duodenum were collected with catheters, and additionally washings from the oral cavity and anal swabs or samples of faeces. Materials were inoculated on Sabouraud's media. The axenic strains of fungi were identified using own methods and others tests (API 20C, API 20C AUX). The activity of ketoconazole (K) was measured against 100 strains of Candida: C. albicans (91 strains), C. kefyr (4), C. famata (2). C. tropicalis (1), C. guilliermondii (1), C. glabrata (1). The strains susceptibility to K (RO4 1400 Janssen) was estimated with the own system based on the dose - response curves; the minimal inhibitory concentration (MIC) values were canculated. The low values of MIC indicate high susceptibility to K of examined Candida strains.
Źródło:
Wiadomości Parazytologiczne; 2001, 47, 4; 929-933
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktywnosc enzymatyczna szczepow grzybow wyizolowanych ze skory i jej przydatkow od osob powracajacych z tropiku
Autorzy:
Glowacka, A
Ochecka-Szymanska, A.
Powiązania:
https://bibliotekanauki.pl/articles/836269.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
podroze zagraniczne
choroby czlowieka
aktywnosc enzymatyczna
parazytologia lekarska
kraje tropikalne
paznokcie
infekcja grzybowa
izolacja grzybow
skora
szczepy grzybow
Opis:
The aim of the work was to assess the enzymatic activity of 11 fungi strains isolated from the skin of 10 Łódź residents who had visited the tropics over 1998-1999. The strains were cultured by Jeske and Lupa of The Voivodeship Outpatient Clinie of Infectious, Parasitic and Tropical Diseases and Fungal Infections in Łódź. They were as follows: Trichophyton rubrum and Acremonium kiliense from Zambia, Myriodontium keratinophilum, Beauveria bassiana, Cladosporium herbarum, Candida famata and Trichophyton yaoundei from Sudan, Trichophyton tonsurans from Ethiopia, Trichophyton phaseliforme from Egypt, Acremonium strictum from Zimbabwe and Microsporum racemosus from Tanzania. The enzymatic activity was determined with the use of API ZYM of bioMerieux enabling 19 hydrolases to be revealed. In general, all tropical strains were characterised by a weak hydrolytic activity.
Źródło:
Annals of Parasitology; 2001, 47, 4; 729-733
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Charakterystyka cech fenotypowych gatunkowych i wewnątrzgatunkowych szczepów grzybów wyodrębnionych z wybranych ontocenoz narządowych osób po przeszczepach nerek
Autorzy:
Kurnatowska, A.
Kurnatowska, I.
Kacprzyk, F.
Chrzanowski, W.
Powiązania:
https://bibliotekanauki.pl/articles/2147753.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
zmiennosc wewnatrzgatunkowa
zmiennosc gatunkowa
cechy fenotypowe
zakazenia grzybicze
nerki
przeszczepy narzadowe
parazytologia lekarska
pacjenci
szczepy grzybow
narzady wewnetrzne
Opis:
Characteristics or phenotypic specific and intraspecific reatures of fungal strains isolated from the organ ontocenoses in patients after renal transplantation. The aim of present study was to describe 60 specific and intraspecific features of fungal strains isolated from the organ ontocenoses: oral cavity, rectum and genital organs in 32 patients undergoing permanent immunosupression after renal transplantation. Fungal strains identified using API 20 C and API 20 C AUX (bioMérieux). The activity or 19 hydrolases was investigated using API ZYM. Among 41 strains of fungi the following were found: Candida albicans (31 strains), C. glabrata (5), C. guilliermondii (2), C. krusei (2) and Saccharomyces cerevisiae (1). The number of fungal strains isolated from the oral cavity was the highest (21), less numerous from rectum (12) and the least from the genital organs (8). The enzymograms were described for all strains and the highest activity was noted in case of: e₆ -leucine arylamidase, e₁₁-phosphatase acid, e₃-esterase (C4), e₁₂-naphtol-AS-BI-phosphohydrolase. The activity of these enzymes is connected with higher pathogenicity of C. albicans strains.
Źródło:
Wiadomości Parazytologiczne; 2002, 48, 4; 425-433
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktywność enzymatyczna szczepów grzybów wyizolowanych ze skóry i jej przydatków od osób powracajacych z tropiku
THE ENZYMATIC ACTIVITY OF FUNGI STRAINS ISOLATED FROM THE SKIN AND SKIN APPENDAGES OF HUMANS RETURNING FROM THE TROPICS
Autorzy:
Głowacka, A.
Ochęcka-Szymańska, A.
Powiązania:
https://bibliotekanauki.pl/articles/2148144.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
podroze zagraniczne
choroby czlowieka
aktywnosc enzymatyczna
parazytologia lekarska
kraje tropikalne
paznokcie
infekcja grzybowa
izolacja grzybow
skora
szczepy grzybow
Opis:
The aim of the work was to assess the enzymatic activity of 11 fungi strains isolated from the skin of 10 Łódź residents who had visited the tropics over 1998-1999. The strains were cultured by Jeske and Lupa of The Voivodeship Outpatient Clinie of Infectious, Parasitic and Tropical Diseases and Fungal Infections in Łódź. They were as follows: Trichophyton rubrum and Acremonium kiliense from Zambia, Myriodontium keratinophilum, Beauveria bassiana, Cladosporium herbarum, Candida famata and Trichophyton yaoundei from Sudan, Trichophyton tonsurans from Ethiopia, Trichophyton phaseliforme from Egypt, Acremonium strictum from Zimbabwe and Microsporum racemosus from Tanzania. The enzymatic activity was determined with the use of API ZYM of bioMerieux enabling 19 hydrolases to be revealed. In general, all tropical strains were characterised by a weak hydrolytic activity.
Źródło:
Wiadomości Parazytologiczne; 2001, 47, 4; 729-733
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrazliwosc na mikonazol i itrakonazol szczepow grzybow z rodzaju Candida wyodrebnionych od pacjentow hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:
Kurnatowska, A.K.
Kwasniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/840111.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Źródło:
Annals of Parasitology; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrażliwość na mikonazol i itrakonazol szczepów grzybów z rodzaju Candida wyodrębnionych od pacjentów hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:
Kurnatowska, A.K.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2143561.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Opis:
It is known that fungi representing different genera and species can cause organ-limited or systemic infections after disrupting of the natural defense mechanisms in a human organism. The treatment of mycoses still encounters considerable difficulties. Therefore, in vitro assessment of the susceptibility of fungal strains to the antifungal agents now in use and to new drugs is needed more urgently than ever before. It should be emphasized that we treat the fungal susceptibility to antifungal drugs as a quantitative feature of the strain examined. The aim of the presently reported study was the evaluation of the antimycotic action of two azole compounds – miconazole and itraconazole (Janssen) against 205 Candida strains isolated from the various biological specimens of two groups of patients – hospitalized (group 1) and examined in outpatient clinic (group 2); differentiation of species and codes of these strains; analysis of dose-response curves and parameters of polygons of the azoles minimal inhibitory concentrations (MIC). The susceptibility to miconazole and itraconazole was estimated with the agar diffusion test on 3% Sabouraud’s agar – the method developed in our laboratory, using several different concentrations of the drug, which made the plotting of dose-response curves possible. The lowest concentration inhibiting the growth of fungal strain (MIC) was calculated using a transformed equation of rectilinear regression according to Kadłubowski. Species and fungal codes of isolated strains were evaluated according to the guidelines worked out in our department with the use of different media and biochemical tests (bioMérieux). Among 89 strains isolated from the hospitalized patients, six species of the genus Candida genus were found; one strain belonged to Trichosporon cutaneum species. The most frequently encountered species was Candida albicans (73%), which significantly dominated over C. tropicalis, C. parapsilosis, C. glabrata, C. lipolytica and C. famata. All strains from the second group of patients belonged to C. albicans species. In all C. albicans strains from both groups of patients, the most frequent assimilation code (2576174) was found. The miconazole MIC values for Candida strains isolated from the group 1 were characterized by a wide range of variation, from 0.0247mg/l to 6.826 mg/l, from group 2 – 0.0277 to 0.719 mg/l. The itraconazole MIC values were 0.011 to 2.813 mg/l, and 0.0103 to 0.718 mg/l, respectively. The analysis of mean values (x) of miconazole and itraconazole MICs and other parameters allowed us to find that the strains isolated from the patients of group 1 were significantly less susceptible to both drugs in comparison with the strains of the group 2 patients. Also, C. albicans strains from this group of patients had a significantly lower (x) MIC in comparison to the mean values for the most of Candida species isolated from the hospitalized patients (P<0.001). In conclusion, we have found that the most Candida strains from both groups of patients were susceptible to the examined antifungal agents. The strains isolated from the outpatient clinic patients were generally more susceptible especially to itraconazole in comparison with strains from hospitalized patients.
Źródło:
Wiadomości Parazytologiczne; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktywnosc kwasnej proteazy asparaginowej szczepow Candida izolowanych z migdalkow podniebiennych
Autorzy:
Rozga, A
Jaskolowska, A.
Kurnatowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/836842.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
aktywnosc proteolityczna
Candida
parazytologia lekarska
migdalki podniebienne
aktywnosc przeciwgrzybicza
kwasna proteaza asparaginowa
szczepy grzybow
izolaty grzybowe
Opis:
We have evalueated the activity of acidous asparagine protease in 48 strains of Candida isolated from homogenates of palatine tonsils from 116 patients after tonsilectomy. Strains most frequently isolated were C. albicans (66.7±6.8 %) and C. tropicalis (14.6±5.09 %). The range of proteolysis zone for Candida strains was 4.6 to 12.5 mm. Over 60% of the studied strains showed high and very high proteolytic activity (>6.6 mm) and the remaining strains with showed moderate activity (4.6-6.5). There were no strains with low medium activity (to 4.5 mm zone). The range of the number of rosettes E formed by lymphocytes obtained from the studied tonsils was 0-268.3. Lymphocytes isolated from 70 % of tonsils infected with Candida formed only 0-130 rosettes E; in the remaining cases the number ranged between 131 and 220. The number of lymphocytes T forming rosettes E isolated from palatine tonsils from patients not infected with fungi was 2.5 times higher. There was no correlation between the size of proteolysis zone and the number of rosettes E.
Źródło:
Annals of Parasitology; 2001, 47, 4; 875-882
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktywnosc lekow azolowych in vitro wobec szczepow Candida albicans o roznych kodach wyodrebnionych z przewodu pokarmowego dzieci
Autorzy:
Kurnatowski, M.
Kurnatowska, A.
Wasowska-Krolikowska, K.
Powiązania:
https://bibliotekanauki.pl/articles/839706.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Candida albicans
grzyby
przewod pokarmowy
in vitro
parazytologia lekarska
leki przeciwgrzybicze
dzieci
aktywnosc przeciwgrzybicza
szczepy grzybow
Źródło:
Annals of Parasitology; 2004, 50, 3; 387-392
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktywność kwaśnej proteazy asparaginowej szczepów Candida izolowanych z migdalków podniebiennych
ACTIVITY OF ACID ASPARTIC PROTEINASE CANDIDA STRAINS ISOLATED FROM PALATINE TONSILS*
Autorzy:
Rózga, A.
Jaskłowska, A.
Kurnatowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/2148244.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
aktywnosc proteolityczna
Candida
parazytologia lekarska
migdalki podniebienne
aktywnosc przeciwgrzybicza
kwasna proteaza asparaginowa
szczepy grzybow
izolaty grzybowe
Opis:
We have evalueated the activity of acidous asparagine protease in 48 strains of Candida isolated from homogenates of palatine tonsils from 116 patients after tonsilectomy. Strains most frequently isolated were C. albicans (66.7±6.8 %) and C. tropicalis (14.6±5.09 %). The range of proteolysis zone for Candida strains was 4.6 to 12.5 mm. Over 60% of the studied strains showed high and very high proteolytic activity (>6.6 mm) and the remaining strains with showed moderate activity (4.6-6.5). There were no strains with low medium activity (to 4.5 mm zone). The range of the number of rosettes E formed by lymphocytes obtained from the studied tonsils was 0-268.3. Lymphocytes isolated from 70 % of tonsils infected with Candida formed only 0-130 rosettes E; in the remaining cases the number ranged between 131 and 220. The number of lymphocytes T forming rosettes E isolated from palatine tonsils from patients not infected with fungi was 2.5 times higher. There was no correlation between the size of proteolysis zone and the number of rosettes E.
Źródło:
Wiadomości Parazytologiczne; 2001, 47, 4; 875-882
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktywność leków azolowych in vitro wobec szczepów Candida albicans o różnych kodach wyodrębnionych z przewodu pokarmowego dzieci
Activity of the azole drugs in vitro against strains of Candida albicans with different codes isolated from the digestive tract in children.
Autorzy:
Kurnatowski, M.
Kurnatowska, A.
Wąsowska-Królikowska, K.
Powiązania:
https://bibliotekanauki.pl/articles/2147374.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Candida albicans
grzyby
przewod pokarmowy
in vitro
parazytologia lekarska
leki przeciwgrzybicze
dzieci
aktywnosc przeciwgrzybicza
szczepy grzybow
Opis:
The activity of ketoconazole (K, R04 1400 molecular weight 531.44), miconazole (M, RO1 4889, molecular weight 479.15) and itraconazole (I, ROS 1211, molecular weight 705.64) obtained from Janssen Pharmaceutica NV, against Candida albicans strains was studied. The axenic fungal strains were isolated from the faecal samples of children — not previously treated with antifungal drugs — with clinical symptoms suggesting the inflammation of the mucous membrane in the stomach and/or duodenum. The strains were assessed by own methods and unified tests (bioMérieux: API 20 C, API 20 C AUX). Five codes of Candida albicans Berkhout were found. The minimal inhibitory concentration (MIC) values were calculated from 448 dose-response curves according to the agar diffusion —- Kadtubowski’s method. MICs were also examined by analyzing the variation (min-max, x mean + standard error, mode Mo, median Me). It was demonstrated that all the strains used in the study were susceptible to the azoles drugs.
Źródło:
Wiadomości Parazytologiczne; 2004, 50, 3; 387-392
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Charakterystyka cech fenotypowych gatunkowych i wewnatrzgatunkowych szczepow grzybow wyodrebnionych z wybranych ontocenoz narzadowych osob po przeszczepach nerek
Autorzy:
Kurnatowska, A
Kurnatowska, I.
Kacprzyk, F.
Chrzanowski, W.
Powiązania:
https://bibliotekanauki.pl/articles/837373.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
zmiennosc wewnatrzgatunkowa
zmiennosc gatunkowa
cechy fenotypowe
zakazenia grzybicze
nerki
przeszczepy narzadowe
parazytologia lekarska
pacjenci
szczepy grzybow
narzady wewnetrzne
Opis:
Characteristics or phenotypic specific and intraspecific reatures of fungal strains isolated from the organ ontocenoses in patients after renal transplantation. The aim of present study was to describe 60 specific and intraspecific features of fungal strains isolated from the organ ontocenoses: oral cavity, rectum and genital organs in 32 patients undergoing permanent immunosupression after renal transplantation. Fungal strains identified using API 20 C and API 20 C AUX (bioMérieux). The activity or 19 hydrolases was investigated using API ZYM. Among 41 strains of fungi the following were found: Candida albicans (31 strains), C. glabrata (5), C. guilliermondii (2), C. krusei (2) and Saccharomyces cerevisiae (1). The number of fungal strains isolated from the oral cavity was the highest (21), less numerous from rectum (12) and the least from the genital organs (8). The enzymograms were described for all strains and the highest activity was noted in case of: e₆ -leucine arylamidase, e₁₁-phosphatase acid, e₃-esterase (C4), e₁₂-naphtol-AS-BI-phosphohydrolase. The activity of these enzymes is connected with higher pathogenicity of C. albicans strains.
Źródło:
Annals of Parasitology; 2002, 48, 4; 425-433
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena aktywnosci kwasnej proteazy asparaginowej szczepow Candida wyizolowanych z jamy ustnej u pacjentow z podwyzszonym ryzykiem zakazenia grzybami
Autorzy:
Rozga, A
Kurnatowska, A.J.
Raczynska-Witonska, G.
Loga, G.
Powiązania:
https://bibliotekanauki.pl/articles/841502.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
nowotwory
aktywnosc proteolityczna
choroby czlowieka
rak krtani
aktywnosc enzymatyczna
Candida
parazytologia lekarska
pacjenci
kwasna proteaza asparaginowa
wymazy z jamy ustnej
szczepy grzybow
zaburzenia immunologiczne
Opis:
We have evaluated the activity of acid aspartic protease in 195 strains of Candida isolated from the oral cavity of three groups of patients. The first group comprised patients with cancer of the larynx qualified for surgery, the second- patients with neoplastic disease (Hodgkin's disease, lymphoma, acute granulocytic leukaemia, lymphatic leukaemia, lung cancer, multiple myeloma, stomach cancer, breast cancer) who were not treated, the third group- patients with neoplastic diseases treated by chemotherapy. The strains of fungi were differentiated using API 20C and Api 20C AUX tests according to the protocol adopted at the Department of Medical Parasitology and Biology, Medical University of Łódż. The activity of acid protease was studied by Staib method in Rózga modification. Almost all strains showed high and very high proteolytic activity. The rang of proteolysis zone of Candida strains from the three groups of patients varied from 2,5 to 12,5 mm. We have found the mean proteolytic zones of strains isolated from groups Iand III differed statistically significantly (p<0,001). Similarly, statisticall sihnificant difference was seen between these parameters for groups II and III (p<0,05), while there was no difference between strains from group I and II.
Źródło:
Annals of Parasitology; 2001, 47, 4; 883-890
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena aktywności kwaśnej proteazy asparaginowej szczepów Candida wyizolowanych z jamy ustnej u pacjentów z podwyższonym ryzykiem zakażenia grzybami
EVALUTION OF ACTIVITY OF ACID ASPARTIC PROTEINASE IN CANDIDA STRAINS . ISOLATED FROM ORAL CAVITY OF PATIENTS WITH INCREASED RISK OF MYCOSIS
Autorzy:
Rózga, A.
Kurnatowska, A.J.
Raczyńska-Witońska, G.
Loga, G.
Powiązania:
https://bibliotekanauki.pl/articles/2148245.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
nowotwory
aktywnosc proteolityczna
choroby czlowieka
rak krtani
aktywnosc enzymatyczna
Candida
parazytologia lekarska
pacjenci
kwasna proteaza asparaginowa
wymazy z jamy ustnej
szczepy grzybow
zaburzenia immunologiczne
Opis:
We have evaluated the activity of acid aspartic protease in 195 strains of Candida isolated from the oral cavity of three groups of patients. The first group comprised patients with cancer of the larynx qualified for surgery, the second- patients with neoplastic disease (Hodgkin's disease, lymphoma, acute granulocytic leukaemia, lymphatic leukaemia, lung cancer, multiple myeloma, stomach cancer, breast cancer) who were not treated, the third group- patients with neoplastic diseases treated by chemotherapy. The strains of fungi were differentiated using API 20C and Api 20C AUX tests according to the protocol adopted at the Department of Medical Parasitology and Biology, Medical University of Łódż. The activity of acid protease was studied by Staib method in Rózga modification. Almost all strains showed high and very high proteolytic activity. The rang of proteolysis zone of Candida strains from the three groups of patients varied from 2,5 to 12,5 mm. We have found the mean proteolytic zones of strains isolated from groups Iand III differed statistically significantly (p<0,001). Similarly, statisticall sihnificant difference was seen between these parameters for groups II and III (p<0,05), while there was no difference between strains from group I and II.
Źródło:
Wiadomości Parazytologiczne; 2001, 47, 4; 883-890
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-14 z 14

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