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Wyświetlanie 1-2 z 2
Tytuł:
Influence of pectin and chitosan on the properties of gels protecting the oesophageal mucosa
Autorzy:
Małolepsza-Jarmołowska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/2131516.pdf
Data publikacji:
2021
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
anti-inflammatory drugs
gastro-oesophageal reflux
hydrophilic gels
oesophageal infections
oesophageal mucosa
physiological environment of gastro-oesophagus
Opis:
Among the diseases of the digestive tract, gastro-oesophageal reflux is one of the most troublesome ailments. It is estimated that in highly developed countries, reflux symptoms occur in about 5%-10% of people every day. It has also been found that about 20% of people experience such symptoms once a week. The incidence of this disease increases with age, regardless of gender. The aim of the study was to investigate the physicochemical properties of gels intended for the protection of the oesophageal mucosa. Preparations containing 3.0% pectin showed the lowest pH. These gels can be used in the treatment of advanced alkaline reflux. The addition of chitosan to all tested gels increased their pH and dynamic viscosity. The texture tests showed the effect of pectin concentration on the adhesion work of the tested gels.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2021, 26; 162-169
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of chitosan on the properties of gels protecting of the esophageal mucosa
Autorzy:
Małolepsza-Jarmołowska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1034174.pdf
Data publikacji:
2019
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
anti-inflammatory drugs
esophageal infections.
esophageal mucosa
gastro-esophageal reflux
hydrophilic gels
physiological environment of gastro-esophageal
Opis:
Gastro-esophageal reflux is a term that defines the reverse flow of acid gastric contents into the esophagus. On the other hand, alkaline reflux occurs in the case when alkaline intestinal contents enter the esophagus. The aim of the study was to examine the pharmaceutical properties of gels for the treatment of gastro-esophageal reflux, covering the mucosa, allowing prolonged contact with the esophageal mucosa. Formulations containing the PVP K-30 showed the lowest pH, which is an important feature and can be used in the treatment of advanced alkaline reflux. Gels containing PVP K-90 and chitosan can be used in the treatment of acid reflux. The addition of chitosan significantly increased the dynamic viscosity of the tested gels. The study of the work of adhesion showed the effect of PVP K-30 and PVP K-90 and their concentration on the value of the work of adhesion. The presented studies have shown that it is possible to obtain gels with high adhesion to the esophageal mucous membrane.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2019, 24; 135-144
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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