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Wyświetlanie 1-8 z 8
Tytuł:
Niektore parametry odpornosci u pacjentow z rzesistkowica jamy ustnej powiklanej grzybica [trichomonosomycosis]
Autorzy:
Kurnatowska, A J
Kurnatowska, P.
Powiązania:
https://bibliotekanauki.pl/articles/841239.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
odpornosc czlowieka
Trichomonas tenax
czynniki chorobotworcze
Candida
rzesistek policzkowy
parazytologia lekarska
odpornosc humoralna
choroby grzybowe
pasozyty
odpornosc komorkowa
rzesistkowica
grzybice
Opis:
The objective of the study was the analysis of selected parameters of humoral and cellular immunity in patients with Trichomonas tenax and fungi existing concurrently in the oral cavity ontocenosis. The study included 37 patients (age range 26-70 years, x=54.5±4.l) diagnosed with trichomonosomycosis. Standard methods were used to determine the total level of protein and its individual fractions, leukocytosis and sedimentation rate. Serum levels of immunoglobulins IgA, IgM and IgG, and the level of IgA immunoglobulin in saliva (S-IgA) were determined with the immunodilTussion method using NOR-Partigen and LC-Partigen (Behring) platelets. To define blastic and miotic indices (IB and IM), rosette tests ER, EAR and EACR as well as phytohemagglutinin-induced (PHA) blastic transformation test were employed. In 21.1% of patients, a decrease in total protein level (on the average 6.85±0.23 g/dl), and in 11.1% in globulins of y fraction (18.5±1.18%) was observed, in 40% of cases the leukocytes count was higher (10080±690.7), and in all patients the sedimentation rate was accelerated (77.9±12.2 mm). The level of class A immunoglobulins (368.7±49,0 mg%) was in 29.2% above norm, and of IgG class (1182.8±92.9 mg%) was in 13.6% below norm and in 13.6% above norm. In case of S-IgA (8.15±0.63 mg%), the level was below norm in all patients. Also in all patients a decreased lymphocytes T count (value ER - 37.3±1.04%) and deficiency in their function (indices: IB 22.5±2.98%, IM 2.3±0.84%) could be observed, whereas lymphocytes B count was increased (values EAR - 18.3±0.7%; values EACR -22.1-0.77). These data indicate that in cases of oral trichmonosomycosis there occurs a low level of secretory immunoglobulin class A in saliva and the number of lymphocytes T, deficient in function, is decreased.
Źródło:
Annals of Parasitology; 1998, 44, 1; 41-45
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Niektóre parametry odporności u pacjentów z rzęsistkowicą jamy ustnej powikłanej grzybicą [trichomonosomycosis]
SELECTED PARAMETERS OF IMMUNITY IN PATIENTS WITH ORAL TRICHOMONOSIS COMPLICATED BY MYCOSIS (TRICHOMONOSOMYCOSIS)
Autorzy:
Kurnatowska, A. J.
Kurnatowska, P.
Powiązania:
https://bibliotekanauki.pl/articles/2148843.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
odpornosc czlowieka
Trichomonas tenax
czynniki chorobotworcze
Candida
rzesistek policzkowy
parazytologia lekarska
odpornosc humoralna
choroby grzybowe
pasozyty
odpornosc komorkowa
rzesistkowica
grzybice
Opis:
The objective of the study was the analysis of selected parameters of humoral and cellular immunity in patients with Trichomonas tenax and fungi existing concurrently in the oral cavity ontocenosis. The study included 37 patients (age range 26-70 years, x=54.5±4.l) diagnosed with trichomonosomycosis. Standard methods were used to determine the total level of protein and its individual fractions, leukocytosis and sedimentation rate. Serum levels of immunoglobulins IgA, IgM and IgG, and the level of IgA immunoglobulin in saliva (S-IgA) were determined with the immunodilTussion method using NOR-Partigen and LC-Partigen (Behring) platelets. To define blastic and miotic indices (IB and IM), rosette tests ER, EAR and EACR as well as phytohemagglutinin-induced (PHA) blastic transformation test were employed. In 21.1% of patients, a decrease in total protein level (on the average 6.85±0.23 g/dl), and in 11.1% in globulins of y fraction (18.5±1.18%) was observed, in 40% of cases the leukocytes count was higher (10080±690.7), and in all patients the sedimentation rate was accelerated (77.9±12.2 mm). The level of class A immunoglobulins (368.7±49,0 mg%) was in 29.2% above norm, and of IgG class (1182.8±92.9 mg%) was in 13.6% below norm and in 13.6% above norm. In case of S-IgA (8.15±0.63 mg%), the level was below norm in all patients. Also in all patients a decreased lymphocytes T count (value ER - 37.3±1.04%) and deficiency in their function (indices: IB 22.5±2.98%, IM 2.3±0.84%) could be observed, whereas lymphocytes B count was increased (values EAR - 18.3±0.7%; values EACR -22.1-0.77). These data indicate that in cases of oral trichmonosomycosis there occurs a low level of secretory immunoglobulin class A in saliva and the number of lymphocytes T, deficient in function, is decreased.
Źródło:
Wiadomości Parazytologiczne; 1998, 44, 1; 41-45
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rzesistkowica jamy ustnej powiklana grzybica [trichomonosomycosis]
Autorzy:
Kurnatowska, A J
Kurnatowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/837884.pdf
Data publikacji:
1999
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
choroby pasozytnicze
choroby czlowieka
rzestkowica jamy ustnej
powiklania chorobowe
parazytologia
grzybice
Opis:
Protozoa and fungi of the oral cavity, although frequently occuring and connected with considerable clinical adverse effects, are as yet insufficiently known. The aims of the study were to estimate the prevalence of common invasions of Trichomonas tenax and fungi, to associate the symptoms with the diagnosis of trichomonosis complicated by mycosis and to determine trichomonacidal properties of ornidazole, tinidazole and metronidazole. 936 dentist patients with different diagnoses were included into the study. The collected material consisted of rinsings, with simultaneous application of selective media, different for protozoa and for fungi cultures. Among the examined patients T. tenax was found in 90 cases including 85 cases where it occurred together with fungi (11 species), on the basis of which the diagnosis of trichomonosomycosis of the oral cavity was established. It was the most often in patients with leukoplakia and Lichen Wilsoni. We received a statistically significant association (0.001
Źródło:
Annals of Parasitology; 1999, 45, 2; 129-133
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Odpowiedz immunologiczna na zarazenie grzybami
The immune response to fungal infections
Autorzy:
Kurnatowski, P
Kurnatowska, A.J.
Powiązania:
https://bibliotekanauki.pl/articles/838620.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
patogeny grzybowe
infekcja grzybowa
grzybice
mechanizmy odpornosciowe
uklad odpornosciowy
odpowiedz immunologiczna
Źródło:
Annals of Parasitology; 2010, 56, 1; 23-27
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rzęsistkowica jamy ustnej powikłana grzybicą [trichomonosomycosis]
Autorzy:
Kurnatowska, A. J.
Kurnatowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/2148748.pdf
Data publikacji:
1999
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
choroby pasozytnicze
choroby czlowieka
rzestkowica jamy ustnej
powiklania chorobowe
parazytologia
grzybice
Opis:
Protozoa and fungi of the oral cavity, although frequently occuring and connected with considerable clinical adverse effects, are as yet insufficiently known. The aims of the study were to estimate the prevalence of common invasions of Trichomonas tenax and fungi, to associate the symptoms with the diagnosis of trichomonosis complicated by mycosis and to determine trichomonacidal properties of ornidazole, tinidazole and metronidazole. 936 dentist patients with different diagnoses were included into the study. The collected material consisted of rinsings, with simultaneous application of selective media, different for protozoa and for fungi cultures. Among the examined patients T. tenax was found in 90 cases including 85 cases where it occurred together with fungi (11 species), on the basis of which the diagnosis of trichomonosomycosis of the oral cavity was established. It was the most often in patients with leukoplakia and Lichen Wilsoni. We received a statistically significant association (0.001
Źródło:
Wiadomości Parazytologiczne; 1999, 45, 2; 129-133
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Odpowiedź immunologiczna na zarażenie grzybami
The immune response to fungal infections
Autorzy:
Kurnatowski, P.
Kurnatowska, A.J.
Powiązania:
https://bibliotekanauki.pl/articles/2143402.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
patogeny grzybowe
infekcja grzybowa
grzybice
mechanizmy odpornosciowe
uklad odpornosciowy
odpowiedz immunologiczna
Opis:
In mycoses congenital – nonspecific innate as well as acquired immunity (involving neutrophiles, monocytes, macrophages, dendritic cells and lymphocytes) both play important roles in host defence. Th1 lymphocytes release cytokines (IL-2, IL-12, IFNg) and stimulate cytotoxic cells and neutrophiles to destroy fungal cells. Th2 lymphocytes, on the other hand, suppress cellular immunity by releasing the cytokines IL-4, IL-6 and IL-10 which counter regulate the secretion of IL-2, IL-12, IFNg and depress the activity of macrophages. Cellular mechanisms play essential roles in host responses to fungal infections. Dysfunction of T lymphocytes and a reduction in their number are typically observed in patients with mycotic diseases. There occurs a reduction of both T lymphocyte populations and the T-helper to T-suppressor cell number ratio, and these are of critical importance in explaining the diminished IgA production and enhanced adhesion of fungal cells to the surface of host cells as well as in facilitating the intrusion of fungi throughout the skin and mucous membranes. The specific immunological reaction, associated with the synthesis of antibodies against fungal cell wall or cytoplasmic antigens, is of little significance in protective immunity, but nevertheless has a rather important role to play in diagnosis as well as in supporting phagocytosis by inhibition of fungal cell adherence. In patients with mycoses, typically low blood serum level of the immunoglobulin class G and A and low sIgA in saliva are observed. A detailed understanding the nature and function of the immune system in mycoses is necessary to enable improvements in pharmacotherapy with antifungal antibiotics and chemotherapeutics, as well as to treatments based on immunotherapy and vaccination.
Źródło:
Wiadomości Parazytologiczne; 2010, 56, 1; 23-27
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrazliwosc na mikonazol i itrakonazol szczepow grzybow z rodzaju Candida wyodrebnionych od pacjentow hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:
Kurnatowska, A.K.
Kwasniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/840111.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Źródło:
Annals of Parasitology; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrażliwość na mikonazol i itrakonazol szczepów grzybów z rodzaju Candida wyodrębnionych od pacjentów hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:
Kurnatowska, A.K.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2143561.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Opis:
It is known that fungi representing different genera and species can cause organ-limited or systemic infections after disrupting of the natural defense mechanisms in a human organism. The treatment of mycoses still encounters considerable difficulties. Therefore, in vitro assessment of the susceptibility of fungal strains to the antifungal agents now in use and to new drugs is needed more urgently than ever before. It should be emphasized that we treat the fungal susceptibility to antifungal drugs as a quantitative feature of the strain examined. The aim of the presently reported study was the evaluation of the antimycotic action of two azole compounds – miconazole and itraconazole (Janssen) against 205 Candida strains isolated from the various biological specimens of two groups of patients – hospitalized (group 1) and examined in outpatient clinic (group 2); differentiation of species and codes of these strains; analysis of dose-response curves and parameters of polygons of the azoles minimal inhibitory concentrations (MIC). The susceptibility to miconazole and itraconazole was estimated with the agar diffusion test on 3% Sabouraud’s agar – the method developed in our laboratory, using several different concentrations of the drug, which made the plotting of dose-response curves possible. The lowest concentration inhibiting the growth of fungal strain (MIC) was calculated using a transformed equation of rectilinear regression according to Kadłubowski. Species and fungal codes of isolated strains were evaluated according to the guidelines worked out in our department with the use of different media and biochemical tests (bioMérieux). Among 89 strains isolated from the hospitalized patients, six species of the genus Candida genus were found; one strain belonged to Trichosporon cutaneum species. The most frequently encountered species was Candida albicans (73%), which significantly dominated over C. tropicalis, C. parapsilosis, C. glabrata, C. lipolytica and C. famata. All strains from the second group of patients belonged to C. albicans species. In all C. albicans strains from both groups of patients, the most frequent assimilation code (2576174) was found. The miconazole MIC values for Candida strains isolated from the group 1 were characterized by a wide range of variation, from 0.0247mg/l to 6.826 mg/l, from group 2 – 0.0277 to 0.719 mg/l. The itraconazole MIC values were 0.011 to 2.813 mg/l, and 0.0103 to 0.718 mg/l, respectively. The analysis of mean values (x) of miconazole and itraconazole MICs and other parameters allowed us to find that the strains isolated from the patients of group 1 were significantly less susceptible to both drugs in comparison with the strains of the group 2 patients. Also, C. albicans strains from this group of patients had a significantly lower (x) MIC in comparison to the mean values for the most of Candida species isolated from the hospitalized patients (P<0.001). In conclusion, we have found that the most Candida strains from both groups of patients were susceptible to the examined antifungal agents. The strains isolated from the outpatient clinic patients were generally more susceptible especially to itraconazole in comparison with strains from hospitalized patients.
Źródło:
Wiadomości Parazytologiczne; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-8 z 8

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