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Wyświetlanie 1-9 z 9
Tytuł:
The role of photodynamic therapy as a novel strategy in clinical practice
Autorzy:
Kwiatkowski, Stanisław
Cyranowski, Salwador
Beata, Beata Joanna
Powiązania:
https://bibliotekanauki.pl/articles/1178848.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
PDT
Photodynamic therapy
cancer
light delivery
light therapy
photosensitizer
Opis:
Photodynamic therapy (PDT) is a novel non-invasive form of light therapy. PDT can be widely applied in various fields of clinical approach, particularly in the treatment of dysplastic conditions and malignant tumours of the brain, gastrointestinal tract, respiratory and reproductive systems. PDT is most frequently utilised in oncological dermatology; however, it could be easily used in the treatment of acne, skin mycosis or viral infections, e.g. HSV infection. The mechanism of PDT is based on the irritation of a chemical, a so-called photosensitizer that was selectively accumulated in a particular pathological tissue, by the light. The outcome of this irritation is a photochemical reaction that transform the photosensitizer into an active toxic substance that destroys the non-functional cells. The advantages of PDT include high efficacy and selectivity, the possibility of multiple administration of light doses and no evident contraindications of simultaneous usage of PDT and other therapeutic methods in patients of various clinical conditions. Moreover, virtually none side effects and excellent cosmetic effects are making PDT a very well tolerated therapy for many patients. Further steps are taken to introduce PDT in the treatments of cardiovascular disorders, e.g. atherosclerosis, eye disorders or photojuvenation of the skin.
Źródło:
World Scientific News; 2017, 89; 16-21
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Spectrum of gluten-related disorders: celiac disease, wheat allergy, baker’s asthma and non-celiac gluten sensitivity
Autorzy:
Kolasińska, Karolina
Kwiatkowski, Stanisław
Czerwiński, Grzegorz
Poniewierka, Elżbieta
Waszczuk, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1177771.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
celiac disease
gluten
non-celiac gluten sensitivity
wheat allergy
Opis:
Gluten, which is a protein found in wheat, can trigger some gastrointestinal diseases in people with genetic predisposition. Gluten related disorders include celiac disease (CD), wheat allergy, baker’s asthma and non-celiac gluten sensivity (NCGS). Approximately 1% of population suffers from celiac disease. It is believed, that the occurrence of the disease is determined by the interaction of genetic, immunological and environmental factors. The consequence of the inflammatory process is the atrophy of the intestinal villi. That results in impaired bowel motility, improper digestion and impaired absorption of substances contained in the diet. Wheat allergy occurs among people with a genetic predisposition to allergies. People with this disorder are sensitized to products containing gluten and every contact with this antigen leads to mast cell activation and the release of mediators of the allergic reaction - mainly histamine. They mainly affect the skin (urticaria, atopic eczema, angioedema), digestive system (nausea, vomiting, spasmic abdominal pain) and respiratory tract (asthma, allergic rhinitis). Baker’s asthma is an interesting and common allergic, occupational disorder related to inhalation of flour containing gluten. The main symptoms include: conjunctivitis, rhinitis, dermatitis, as well as work-related cough and dyspnea. First reports on non-celiac gluten sensitivity (NCGS) appeared in 1980. The diagnosis of non-celiac gluten sensitivity is based on the exclusion of celiac disease and food allergy in a patient who has symptoms induced by ingestion of gluten. The exact pathomechanism of this disease is still unknown. Interestingly, some researches doubt that this disorder is caused by gluten intake. All of the above-mentioned diseases have a similar spectrum of clinical symptoms, and as part of the treatment require an elimination diet with the exclusion of gluten. The aim of this study is to provide information on gluten-related diseases, taking into account their pathomechanism and clinical picture.
Źródło:
World Scientific News; 2018, 100; 154-164
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The guide through brain-gut-enteric microbiota axis – regulation pathways and related disorders
Autorzy:
Kolasińska, Karolina
Kwiatkowski, Stanisław
Knap, Bartosz
Czerwiński, Grzegorz
Poniewierka, Elżbieta
Waszczuk, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1163424.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
brain-gut axis
enteric microbiota
gastrointestinal system
Opis:
The brain-gut axis is a complex system of connections between the central nervous system (CNS) and the digestive tract. Information within the axis is transmitted through many pathways (neural, endocrine, metabolic, immunological) and is strongly dependent on the microbiota inhabiting the gut. Therefore, the brain-gut axis is also called the “brain-gut-enteric microbiota axis”. Many studies are carried out to determine how it functions but the exact mechanism is still poorly understood. Unraveling the mystery of brain-gut-enteric microbiota axis seems to be crucial in understanding of many diseases and processes governing the human body.
Źródło:
World Scientific News; 2018, 109; 115-130
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Helicobacter pylori infection: from biology to clinical features
Autorzy:
Kolasińska, Karolina
Kwiatkowski, Stanisław
Knap, Bartosz
Czerwiński, Grzegorz
Poniewierka, Elżbieta
Waszczuk, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1165561.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Helicobacter pylori
MALT lymphoma
gastric cancer
peptic ulcer disease
Opis:
The discovery of bacterium Helicobacter pylori and the association of its occurrence with gastritis and peptic ulcer disease, was one of the most significant events of the 20th century. Almost 40 years have passed since that event, but we are still far from fully understanding of the impact of H. pylori infection on the human body. It is confirmed, that the infection causes chronic gastritis, which increases the risk of diseases such as: duodenal and/or gastric ulcer, gastric cancer and gastric MALT lymphoma. Nevertheless, constantly appear new studies linking H. pylori with many other disorders, often not directly related to the digestive system. Cardiovascular, neurological, hematological, dermatological, metabolic and also gynecological diseases are in sphere of assumptions. The authors of the following work attempted to select key information available in the medical literature on the discovery of H. pylori, epidemiology and pathophysiology of infection, as well as diseases to which it predisposes and the latest methods of eradication.
Źródło:
World Scientific News; 2018, 107; 171-184
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Current clinical management of malignant melanoma – diagnosis process and innovative therapies
Autorzy:
Kwiatkowski, Stanisław
Przystupski, Dawid
Kotowski, Krzysztof
Kolasińska, Karolina
Saczko, Jolanta
Kulbacka, Julita
Powiązania:
https://bibliotekanauki.pl/articles/1177464.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
AJCC
Melanoma malignum
dabrafenib
electrochemotherapy
ipilimumab
melanoma
melanoma staging
pembrolizumab
photodynamic therapy
vemurafenib
Opis:
Malignant melanoma is a highly invasive cancer which derives from neuroectodermic melanocytic cells. It is characterized by the highest frequency of cases in both sexes and all age groups. High metastatic potential of melanoma and its multidrug resistance might be a significant problem in the treatment. Permanent and complete remissions are rare, while the 5-year survival rate remains relatively low. In the last years there has been a breakthrough in the systemic therapy of malignant melanoma. Modern drugs have revolutionized previous therapeutic management of melanoma. As part of therapeutic programs, new medicines are available: dabrafenib, ipilimumab, pembrolizumab, trametinib and vemurafenib. The following paper presents current clinical management standards for melanoma diagnoses, based on the widely accepted scientific data and expert experience - with emphasis on modern methods of treatment of this cancer.
Źródło:
World Scientific News; 2018, 102; 30-46
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An overview of paraneoplastic neurological syndromes – pathophysiology and clinical insight
Autorzy:
Kwiatkowski, Stanisław
Kolasińska, Karolina
Knap, Bartosz
Przystupski, Dawid
Kotowski, Krzysztof
Bartosik, Weronika
Kulbacka, Julita
Powiązania:
https://bibliotekanauki.pl/articles/1163959.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
dermatomyositis
encephalitis
opsoclonus-myoclonus
paraneoplastic neurological syndromes
Opis:
Paraneoplastic syndrome (PS) is a dysfunction of organs or systems, associated with neoplastic disease, but not related to the local growth of tumor, metastasis or adverse anti-cancer drugs reactions. Neurological paraneoplastic syndromes (NPSs) may affect every region of a human nervous system - both central, peripheral, and/or autonomic nervous system. The symptoms are caused by a neoplastic process in other organ or system. PNSs usually precede the development of cancer for months or even years, and can be therefore useful diagnostic markers of cancer. They present an autoimmune background associated with the response of the immune system against cancer cells. In the blood serum and cerebrospinal fluid of patients with PNS appear onconeural antibodies, reacting with tumor antigens and the brain, the spinal cord and peripheral ganglia antigens. Many authors emphasize the significance of paraneoplastic syndromes in the modern oncology. Due to this reason, the knowledge of paraneoplastic syndromes and their mechanisms is very important in the contemporary medicine. The purpose of this research review is to summarize the information about the clinical features of the most common PNSs and the pathological mechanisms of their development.
Źródło:
World Scientific News; 2018, 108; 87-98
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A review of current literature on the diagnosis, prophylaxis and treatment of HIV/AIDS
Autorzy:
Sobieski, Mateusz
Przystupski, Dawid
Korzeniewska, Aleksandra
Kwiatkowski, Stanisław
Górska, Agata
Kotowski, Krzysztof
Baczyńska, Dagmara
Powiązania:
https://bibliotekanauki.pl/articles/1162996.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
AIDS
AIDS-related cancers
HIV
cART
Opis:
Acquired immunodeficiency syndrome (AIDS) is a spectrum of various diseases associated with the human immunodeficiency virus (HIV) infection. AIDS is one of the most common infectious illness with 1.8 million of new cases and approximately 36.7 million living with HIV. AIDS becomes a worldwide problem and due to rising number of HIV-positive patients, the appropriate medical care is needed. This article takes into consideration the current information about pathogenesis of HIV infection, clinical and biochemical symptoms, diagnosis, prophylaxis and treatment the disease. Furthermore, the article describes the side effects of the treatment, the methods of their diagnosis and prevalence, and focuses on the psychological problems of HIV-positive people.
Źródło:
World Scientific News; 2018, 110; 129-146
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Azapirones for the treatment of anxiety – an overview
Autorzy:
Knap, Bartosz
Kwiatkowski, Stanisław
Kolasińska, Karolina
Knap-Czop, Karolina
Przystupski, Dawid
Roguzińska, Sylwia
Kędzierska, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1163274.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
anxiety disorder
azapirones
buspirone
gepirone
ipsapirone
tandospirone
Opis:
Anxiety disorders belong to the most common psychiatric diagnosis. Over the years, benzodiazepines were considered the gold standard for pharmacological treatment of anxiety. They are effective anxiolytics, but unfortunately the long-term use of benzodiazepines is accompanied by many adverse events. An alternative to classical anxiolytics is a relatively new class of psychotherapeutic drugs – azapirones. They are 5-HT1A partial agonists commonly used in the treatment of generalized anxiety disorder and as augmentation for SSRI in social anxiety disorder and depression. Due to the high ratio of benefits to risk, azapirones are extensively studied for their use in other disease entities. The aim of this article was to overviewed current information on azapirones. Their history of development, mechanism of action, pharmacokinetics, interactions, clinical use and their role in the modern pharmacotherapy of anxiety.
Źródło:
World Scientific News; 2018, 109; 14-25
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Contemporary management and novel therapies in ovarian cancer – literature review
Autorzy:
Kotowski, Krzysztof
Przystupski, Dawid
Kwiatkowski, Stanisław
Kolasińska, Karolina
Bartosik, Weronika
Górska, Agata
Saczko, Jolanta
Baczyńska, Dagmara
Kulbacka, Julita
Powiązania:
https://bibliotekanauki.pl/articles/1162168.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Anti-VEGF monoclonal IgG1 antibody
Interval Cytoreductive Surgery
Interval Debuking Surgery
bevacizumab
electrochemotherapy
hormone therapy
immunotherapy
ovarian cancer
photodynamic therapy
Opis:
Ovarian cancer is characterized by an extremely poor prognosis in women with an advanced stage of this carcinoma. In United States every year 20,000 women are diagnosed with ovarian cancer. It is the fifth most frequent cause of death from cancer in females and the most common cause of death for 15 years after diagnosis in women with stage III-IV tumors. Among ovarian neoplasms the most frequent are surface epithelial-stromal tumors. Moreover, non-epithelial ovarian tumors are distinguished. This group matters 10% of patients with diagnosed ovarian tumors. Due to a huge variety of ovarian tumors, the following work focuses mainly on the current clinical treatment of the epithelial ovarian cancer. The following paper summarizes current clinical treatment of epithelial ovarian cancer, including surgical procedure, chemo- and immunotherapy including modern therapeutic approaches.
Źródło:
World Scientific News; 2018, 111; 51-63
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-9 z 9

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