The guide through brain-gut-enteric microbiota axis – regulation pathways and related disorders

The brain-gut axis is a complex system of connections between the central nervous system (CNS) and the digestive tract. Information within the axis is transmitted through many pathways (neural, endocrine, metabolic, immunological) and is strongly dependent on the microbiota inhabiting the gut. Therefore, the brain-gut axis is also called the “brain-gut-enteric microbiota axis”. Many studies are carried out to determine how it functions but the exact mechanism is still poorly understood. Unraveling the mystery of brain-gut-enteric microbiota axis seems to be crucial in understanding of many diseases and processes governing the human body.