- Tytuł:
- BIOLOGICAL ACTIVITY AND POLYPHENOL CONTENT IN SELECTED HERBAL TEA BLENDS USED IN DIABETES
- Autorzy:
-
Bylka, Wiesława
Studzińska-Sroka, Elżbieta
Czapska, Izabela - Powiązania:
- https://bibliotekanauki.pl/articles/895583.pdf
- Data publikacji:
- 2019-12-29
- Wydawca:
- Polskie Towarzystwo Farmaceutyczne
- Tematy:
-
antioxidant activity
Herbal blends
Antidiabetes
α-Glucosidase inhibition - Opis:
- This study aimed to evaluate the antioxidant properties, α -glucosidase inhibitory activity, and the total content of polyphenols and flavonoids in the selected antidiabetic herbal blends (1-6), used traditionally in diabetes. The strongest antioxidant activity (DPPH and CUPRAC) was observed in extracts from blends 1 and 6 (IC50 <70 μg/ml, IC0,5 <110 μg/ml, respectively). Extracts from these blends also contained most of the polyphenolic compounds (>40 mg GAE/g), had a high content of flavonoids (6 - 10.96 mg QE/g, 1 - 7.51 mg QE/g) and the highest α-glucosidase inhibiting capacity (for 1 >90%, for 6 >90% and 5,55%, while for acarbose 1.76% and 0.93% at the 100 μg/ml and 10 μg/ml, respectively).The antioxidant activity of 1 and 6 correlated with the content of polyphenols and α-glucosidase inhibitory properties and indicates the existence of this mechanism in supporting the treatment of type 2 diabetes and diabetic complications by the above preparations.
- Źródło:
-
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 6; 1037-1042
0001-6837
2353-5288 - Pojawia się w:
- Acta Poloniae Pharmaceutica - Drug Research
- Dostawca treści:
- Biblioteka Nauki
Artykuł