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    Wyświetlanie 1-9 z 9
    Tytuł:
    Elemental Mapping of Prostate Tissue by Micro-SRIXE
    Autorzy:
    Banaś, A.
    Banaś, K.
    Falkenberg, G.
    Dyduch, G.
    Kwiatek, W. M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2044669.pdf
    Data publikacji:
    2006-03
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    87.64.-t
    Opis:
    Synchrotron radiation-induced X-ray emission is now a proven analytical method for the determination of trace elements. Better insight of the role of trace elements in tissue samples can be gained by acquiring complete distribution maps of these elements. Our approach is based on the acquisition of digital maps. In this contribution we present two different methods for obtaining normalization matrix: first - based on argon intensity in the single spectrum and second - based on changes of beam current intensity. The region for the scan was carefully chosen according to the histological view of the sample. A total area was scanned with a step size of 15 μm in each direction and measuring time of 30 s per pixel. The thickness of the samples was 15 μm. A polycapillary was used for beam focusing. At the energy of 18 keV the beam size on the sample was approximately 15 μm which is of the order of a cell diameter.
    Źródło:
    Acta Physica Polonica A; 2006, 109, 3; 323-328
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Preliminary Study on Chemical Speciation of Sulphur in Cancerous Tissues
    Autorzy:
    Kwiatek, W. M.
    Banaś, A.
    Banaś, K.
    Kisiel, A.
    Cinque, G.
    Falkenberg, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/2044744.pdf
    Data publikacji:
    2006-03
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    87.64.Gb
    Opis:
    Sulphur is vital for almost all living organisms by participating in a wide variety of metabolic processes. Nevertheless its biochemistry is only partially understood, due to it a few tools such as X-ray absorption near edge structure may be used to determine its chemical speciation in biological system. In this paper we focused on analysis of composition and elemental distribution in tissue structures of biological samples. We examined cancerous and non-cancerous prostate tissues. Experiments were carried out on the L-beam line at the HASYLAB, DESY (Hamburg, Germany) and DAΦNE-Light Facility at the Laboratori Nationali di Frascati (Frascati, Italy). Synchrotron radiation induced X-ray emission measurements reveal the significant differences in concentration of sulphur between cancerous and non-cancerous tissues. X-ray absorption near edge structure spectra show two main types of sulphur that are represented by X-ray peaks at 2476 eV and 2484 eV. This suggests that different sulphur components are present in the measured samples.
    Źródło:
    Acta Physica Polonica A; 2006, 109, 3; 383-387
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Distinguishing Prostate Cancer from Hyperplasia
    Autorzy:
    Kwiatek, W. M.
    Banaś, A.
    Banaś, K.
    Podgórczyk, M.
    Dyduch, G.
    Falkenberg, G.
    Gajda, M.
    Cichocki, T.
    Powiązania:
    https://bibliotekanauki.pl/articles/2044731.pdf
    Data publikacji:
    2006-03
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    87.64.-t
    Opis:
    The prostate gland is the most common site of neoplastic disorders in men. The knowledge of the pathogenesis of benign prostate hyperplasia and prostate cancer is still under investigation. X-ray fluorescence analysis using synchrotron radiation seems to be an appropriate technique to study the elemental composition of biological tissues. The measurements presented in this paper were carried out on the L-beam line at the HASYLAB, DESY (Germany). The observed concentrations of Fe, Cu, Mn, and Zn are significantly higher in cancerous tissues, as compared to normal and hyperplastic ones. Our results reveal also the existence of the two types of hyperplasia.
    Źródło:
    Acta Physica Polonica A; 2006, 109, 3; 377-381
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    X-Ray Absorption Near Edge Structure and Mössbauer Spectroscopy in Study of Iron Valence States in Tissues
    Autorzy:
    Dziedzic-Kocurek, K.
    Banaś, A.
    Kwiatek, W. M.
    Stanek, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2044673.pdf
    Data publikacji:
    2006-03
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    61.18.Fs
    61.10.Ht
    Opis:
    X-ray absorption near edge structure Fe K-edge spectra and $\text{}^{57}$Fe Mössbauer spectra of selected standard compounds were recorded at room temperature. Valence and spin states of Fe in these samples known from Mössbauer spectroscopy were correlated with the shapes of X-ray absorption near edge structure spectra in search of possible application of X-ray absorption near edge structure spectroscopy as analytical tool determining local electronic states of iron in tissues. As an example, the X-ray absorption near edge structure spectra of healthy and cancerous tissues of prostate are shown, suggesting Fe$\text{}^{3+}$ in cancerous tissues.
    Źródło:
    Acta Physica Polonica A; 2006, 109, 3; 341-345
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of μ-FTIR-SR Spectroscopy to Prostate Tissue Analysis
    Autorzy:
    Kwiatek, W.
    Paluszkiewicz, C.
    Banaś, A.
    Kisiel, A.
    Podgórczyk, M.
    Marcelli, A.
    Cestelli Guidi, M.
    Piccinini, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1810277.pdf
    Data publikacji:
    2009-02
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    87.64.km
    87.64.kp
    87.64.Ee
    87.85.jf
    Opis:
    The infrared spectromicroscopy is a quite recent technique rapidly developing thanks to the availability of new instruments and new brilliant synchrotron radiation sources in different areas and in particular to biomedical researches. In order to achieve a diffraction limited spatial resolution in tissue samples, we performed experiments at SINBAD, the synchrotron infrared beamline of the Laboratori Nazionali di Frascati. We characterized the chemical composition of prostate tissue samples taken from patients affected by prostate cancer disease. Different sizes of the pinholes were considered for the measurements. In the case of prostate tissue sections the results show the possibility to determine the intensity ratio of the $CH_2$ and $CH_3$ bands set at 2930 $cm^{-1}$ and 2960 $cm^{-1}$, respectively. Experiments were also performed with a pinhole of 5 μm of diameter and the differences in both histological and chemical compositions of such samples were determined.
    Źródło:
    Acta Physica Polonica A; 2009, 115, 2; 602-605
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Heavy Ion Beams for Radiobiology: Dosimetry and Nanodosimetry at HIL
    Autorzy:
    Kaźmierczak, U.
    Bantsar, A.
    Banaś, D.
    Braziewicz, J.
    Czub, J.
    Jaskóła, M.
    Korman, A.
    Kruszewski, M.
    Lankoff, A.
    Lisowska, H.
    Pietrzak, M.
    Pszona, S.
    Stępkowski, T.
    Szefliński, Z.
    Wojewódzka, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1402627.pdf
    Data publikacji:
    2015-05
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    87.53.Bn
    87.53.-j
    Opis:
    Ionizing radiation induces a variety of DNA lesions, including single and double strand breaks. Large energy deposition precisely localized along the ion track that occurs in the case of heavy ion irradiation can lead to complex types of DNA double strand breaks in exposed biological material. The formation of nuclear double strand breaks triggers phosphorylation of histone H2AX, which can be microscopically visualized as foci in the γ-H2AX assay. Studies with a carbon ion beam are being carried out at the Heavy Ion Laboratory of the University of Warsaw. The γ-H2AX assay as a method of measuring the biological response of cells irradiated with $\text{}^{12}C$ ions as well as the frequency cluster size distributions obtained in the nanodosimetry experiment at HIL will be presented.
    Źródło:
    Acta Physica Polonica A; 2015, 127, 5; 1516-1519
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    X-ray Diffraction and Elemental Analysis of Medical and Environmental Samples
    Autorzy:
    Bielecka, K.
    Kurtek, W.
    Banaś, D.
    Kubala-Kukuś, A.
    Braziewicz, J.
    Majewska, U.
    Pajek, M.
    Wudarczyk-Moćko, J.
    Stabrawa, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/1197663.pdf
    Data publikacji:
    2014-04
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    78.70.En
    87.64.Bx
    32.30.Rj
    87.64.kv
    Opis:
    The results of the elemental and chemical composition analysis of human medical samples (blood, serum, hair, urine, tooth, kidney stones, gallstones) and environmental samples (slag, cereal, vegetables, flour, pork bones, pork meat, fish) are presented. The analysis were performed by application of the total reflection X-ray fluorescence, wavelength dispersive X-ray fluorescence and X-ray powder diffraction methods. With X-ray fluorescence methods the following elements were identified: O, Na, Mg, Al, Si, P, S, Cl, K, Ca, Ti, Mn, Fe, Ni, Cu, Zn, Se, Br, Rb, Sr, Zr, I, Ba, and Pb, whose concentrations were from a few ng/g to tens of percent. For some samples the elemental analysis was extended by X-ray powder diffraction measurements. With this method the chemical composition was determined. In the paper the experimental setups, methodology of samples preparation and methods of carrying out the measurements are described. As an example the X-ray spectra registered for gallstone sample are discussed in detail. Finally, the results of X-ray diffraction and elemental analysis for selected medical and environmental samples are summarized.
    Źródło:
    Acta Physica Polonica A; 2014, 125, 4; 911-918
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Investigation of Gold Nanolayer Properties Using X-Ray Reflectometry and Spectroscopic Ellipsometry Methods
    Autorzy:
    Stabrawa, I.
    Banaś, D.
    Dworecki, K.
    Kubala-Kukuś, A.
    Braziewicz, J.
    Majewska, U.
    Wudarczyk-Moćko, J.
    Pajek, M.
    Góźdź, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/1398825.pdf
    Data publikacji:
    2016-02
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    61.05.cm
    62.23.St
    68.55.-a
    81.07.-b
    Opis:
    X-ray reflectometry and spectroscopic ellipsometry methods were applied for determination of physical properties of gold nonolayers. The nanolayers were prepared by sputtering of gold on different substrates: borosilicate glass, polished crystalline quartz and crystalline silicon. With X-ray reflectometry technique roughness of the substrates and density, thickness and roughness of gold layers were determined. The results showed decrease in density of the gold layers due to their nanometer thickness and that roughness of the underlayer affects roughness of the gold layer. In addition, thicknesses of the gold layers measured with spectroscopic ellipsometry turned out to be in agreement, within the experimental uncertainty, with results of the X-ray reflectometry method.
    Źródło:
    Acta Physica Polonica A; 2016, 129, 2; 233-236
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    X-Ray Fluorescence Techniques in Medical Applications: Reference Values of Elements in Human Serum, Urine and Hair
    Autorzy:
    Majewska, U.
    Banaś, D.
    Braziewicz, J.
    Kubala-Kukuś, A.
    Pajek, M.
    Sychowska, I.
    Wudarczyk-Moćko, J.
    Antczak, G.
    Borkowska, B.
    Góźdź, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/1197643.pdf
    Data publikacji:
    2014-04
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    32.30.Rj
    87.64.kd
    87.64.kv
    Opis:
    The aim of undertaken long-term studies of the elemental composition of human serum, urine, and hair is to define reference values of elements concentration. For this purpose the total reflection X-ray fluorescence method was applied to determination of several elements concentration in human serum, urine and hair (S, K, Ca, Fe, Cu, Zn, Br, P, Cr, and Rb in serum samples; Fe, Cu, Zn, Rb, Cr, Mn, and Sr in urine samples; S, K, Ca, Fe, Cu, Br, Zn, Cl, Ti, Cr, Mn, Ni, and Se in hair samples) in the range of concentration from ppb to several hundred ppm. The method of selection of the control group, the experimental setup and its calibration procedure are described. We also present sample preparation methods and procedure of measurements.
    Źródło:
    Acta Physica Polonica A; 2014, 125, 4; 864-868
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-9 z 9

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