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    Wyświetlanie 1-5 z 5
    Tytuł:
    Particle Flow Code modeling of the mechanical behavior of layered rock under uniaxial compression
    Modelowanie właściwości mechanicznych skał warstwowych w warunkach ściskania jednoosiowego przy zastosowaniu oprogramowania Particle Flow Code(PFC)
    Autorzy:
    Yao, Nan
    Ye, Yi-Cheng
    Hu, Bin
    Wang, Wei-Qi
    Wang, Qi-Hu
    Powiązania:
    https://bibliotekanauki.pl/articles/218969.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    skała warstwowa
    wytrzymałość na ściskanie jednoosiowe
    Particle Flow Code (PFC)
    kąt uwarstwienia
    mikropęknięcia
    layered rock
    uniaxial compression test
    bedding angle
    microcracks
    Opis:
    In this paper, the different mechanical behaviors of layered rocks with different bedding angles during uniaxial compression tests are studied. Numerical simulation models of layered rock are validated based on laboratory tests, and uniaxial compression tests are conducted by using Particle Flow Code (PFC). Using these simulations, the uniaxial compressive strength, failure patterns, development of micro-cracks, and displacement of meso particles are analyzed. When the bedding angle is similar to the failure angle, the macro failure planes develop directly along the beddings, the bedding behavior dictates the behavior of the layered rock, reducing the compressive strength.
    W pracy badano właściwości mechaniczne skał warstwowych zalegających pod różnym kątem uwarstwienia w warunkach ściskania jednoosiowego. Walidację modeli symulacyjnych skał warstwowych przeprowadzono w oparciu o wyniki badań laboratoryjnych, zaś testy ściskania jednoosiowego prowadzono z użyciem pakietu Particle Flow Code (PFC). W oparciu o badania symulacyjne, analizowano wytrzy-małość skał na ściskanie jednoosiowe, modele pękania, powstawanie mikropęknięć i przemieszczenia mezo- cząstek. W przypadku gdy kąt płaszczyzny uwarstwienia ma wartość przybliżoną do kąta pęknięcia, płaszczyzny pękania w skali makro pojawiają się wzdłuż spękań, a układ warstw skalnych determinuje ich wytrzymałość na ściskanie, powodując jej obniżenie.
    Źródło:
    Archives of Mining Sciences; 2019, 64, 1; 181-196
    0860-7001
    Pojawia się w:
    Archives of Mining Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of Neuromedin S on the proliferation of splenic lymphocytes and the cytokine secretion by pulmonary alveolar macrophages in pigs in vitro
    Autorzy:
    Lin, R.
    Wang, Q.
    Qi, B.
    Huang, Y.
    Yang, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/30295.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Neuromedin S (NMS), a 36-amino acid neuropeptide, has been found to be involved in the regulation of the endocrine activity. It has been also detected in immune tissues in mammals, what suggests that NMS may play an important role in the regulation of immune response. The aim of this study was to demonstrate the presence of NMS receptor 1 (NMU1R) and effect of NMS in pig splenic lymphocytes (SPLs) and pulmonary alveolar macrophages (PAMs). The presence of NMU1R in pig SPLs and PAMs was respectively confirmed by reverse transcription-polymerase chain reaction (RT-PCR), western blot analysis and immunocytochemical methods. Furthermore, SPL proliferation was analyzed using the 3-(4,5)-dimethyl-thiahiazo-(-2-yl)-3,5-di-phenytetrazoliumromide (MTT) method. Additionally, the secretion of interleukin (IL)-1β, IL-6 and tumor necrosis factor-α (TNF-α) in PAMs was all measured by enzyme-linked immunosorbent assay (ELISA) kits. In the present study, the results of RT-PCR and western blot analysis revealed that NMU1R mRNA and protein were both expressed in pig SPLs and PAMs, and the immunocytochemical investigations further revealed that the positive signal of NMU1R immunoreactivity was observed in plasma membranes of both SPLs and PAMs. In the in vitro study, we found that at concentrations of 0.001-1000 nM NMS alone or combined with lipopolysaccharide or phytohemagglutinin significantly increased SPL proliferation. Application of ELISA method showed that NMS could induce the secretion of the pro-inflammatory cytokines IL-1β, IL-6 and TNF-α in PAMs. These results suggest that NMS can act as a potently positive pro-inflammatory factor and immunomodulatory agent that affects the immune response of immune cells by combining with its receptor NMU1R.
    Źródło:
    Polish Journal of Veterinary Sciences; 2016, 19, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Seismic damage behaviour of aeolian sand reinforced concrete columns with I-shaped structural steel
    Autorzy:
    Wang, Y. H.
    Wang, H. Y.
    Wang, Y. P.
    Zhao, M.
    Qi, J.
    Huo, G. Z.
    Liu, P. Q.
    Powiązania:
    https://bibliotekanauki.pl/articles/1849772.pdf
    Data publikacji:
    2020
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    piasek eoliczny
    słup żelbetowy
    stal konstrukcyjna
    przekrój I
    zachowanie
    uszkodzenie sejsmiczne
    model uszkodzenia
    aeolian sand
    column
    I-shaped steel
    structural steel
    seismic damage
    behaviour
    damage model
    Opis:
    To promote the application of aeolian sand resources for steel-concrete composite structures, an aeolian sand reinforced concrete column with I-shaped structural steel is proposed in this study. Four specimens are designed and manufactured with different replacement rates of aeolian sand. The seismic behaviour and damage evolution process of the specimens are studied by low-cycle repeated loading tests. Based on the test results, the mechanical characteristics, failure modes, hysteresis curves, skeleton curves, energy dissipation capacity, displacement ductility, and stiffness degradation of the specimens with different replacement rates of aeolian sand are analysed. In addition, the effects of the design parameters on the seismic behaviour of the specimens are also studied. The results show that the indexes of the seismic behaviour can be significantly improved by adding steel. Moreover, a revised damage model is proposed, to better reflect the evolution law of seismic damage of aeolian sand reinforced concrete columns with steel. The proposed model can provide an important reference for seismic damage assessment of the columns.
    Źródło:
    Archives of Civil Engineering; 2020, 66, 4; 633-650
    1230-2945
    Pojawia się w:
    Archives of Civil Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The irp2 and fyuA genes in High Pathogenicity Islands are involved in the pathogenesis of infections caused by avian pathogenic Escherichia coli (APEC)
    Autorzy:
    Tu, J.
    Hue, T.
    Qi, K.
    Shao, Y.
    Huang, B.
    Wang, X.
    Zhou, X.
    Powiązania:
    https://bibliotekanauki.pl/articles/30327.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Avian pathogenic Escherichia coli (APEC) is a major bacterial infectious disease that may lead to local or systemic infections in chickens with clinical manifestations. The irp2-fyuA gene cluster has been confirmed to be the main genes involved in the synthesis of HPI. The objective of this study was to determine the influence of the irp2 and fyuA genes in the high pathogenicity island (HPI) of avian pathogenic Escherichia coli (APEC) on its pathogenicity by knocking out these genes. The ΔAE17 (lacking irp2) and ΔΔAE17 (lacking irp2 and fyuA) strains of APEC were constructed. The ΔAE17 and ΔΔAE17 strains showed significantly impaired capacity to adhere onto DF-1 cells. The LD50 results indicated that the virulence of the ΔAE17 and ΔΔAE17 strains was decreased in comparison with that of the AE17 strain. We concluded that the knock-out of the core HPI genes weakened APEC adhesion onto DF-1 cells, inhibited transcription of virulence genes, and reduced pathogenicity in chicks. The effects of genetic deletion of irp2 and fyuA on APEC were more severe than those produced by deletion of irp2 only, indicating that irp2 and fyuA co-regulate APEC pathogenicity.
    Źródło:
    Polish Journal of Veterinary Sciences; 2016, 19, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Error analysis of the three-phase electrical energy calculation method in the case of voltage-loss failure
    Autorzy:
    Cheng, Han-miao
    Wang, Zhong-dong
    Cai, Qi-xin
    Lu, Xiao-quan
    Gao, Yu-xiang
    Song, Rui-peng
    Tian, Zheng-qi
    Mu, Xiao-xing
    Powiązania:
    https://bibliotekanauki.pl/articles/221096.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    three-phase electrical energy meter
    voltage-loss failure
    voltage substitution
    three-phase voltage unbalance
    calculation error
    Opis:
    The single-phase voltage loss is a common fault. Once the voltage-loss failure occurs, the amount of electrical energy will not be measured, but it is to be calculated so as to protect the interest of the power supplier. Two automatic calculation methods, the power substitution and the voltage substitution, are introduced in this paper. Considering the lack of quantitative analysis of the calculation error of the voltage substitution method, the grid traversal method and MATLAB tool are applied to solve the problem. The theoretical analysis indicates that the calculation error is closely related to the voltage unbalance factor and the power factor, and the maximum calculation error is about 6% when the power system operates normally. To verify the theoretical analysis, two three-phase electrical energy metering devices have been developed, and verification tests have been carried out in both the lab and field conditions. The lab testing results are consistent with the theoretical ones, and the field testing results show that the calculation errors are generally below 0.2%, that is correct in most cases.
    Źródło:
    Metrology and Measurement Systems; 2019, 26, 3; 505-516
    0860-8229
    Pojawia się w:
    Metrology and Measurement Systems
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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