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Wyszukujesz frazę "B-cell" wg kryterium: Temat


Wyświetlanie 1-5 z 5
Tytuł:
Opposite changes of regulatory T cell blood content may differentially contribute to atherosclerosis or lymphoproliferative disorders
Autorzy:
Pylaeva, Ekaterina
Potekhina, Aleksandra
Pogorelova, Olga
Tripoten, Maria
Balakhonova, Tatiana
Filatova, Anastasia
Klesareva, Elena
Afanasieva, Olga
Noeva, Elena
Arefieva, Tatiana
Powiązania:
https://bibliotekanauki.pl/articles/1064986.pdf
Data publikacji:
2016
Wydawca:
Medical Education
Tematy:
B-cell chronic lymphocytic leukemia
Opis:
Background. Chronic autoimmune inflammation in arterial wall may lead to atherosclerosis progression. Objective. The aim of this study was to investigate the association between Treg, Th17 and B1a cell blood frequencies as well as IgM autoantibodies to oxLDL and the abundance of carotid atherosclerosis. Material and methods. 18 patients with increased IMT (intima-media thickness) and 65 patients with different severity of carotid atherosclerotic plaques were included. Treg, Th17 and B1a cell blood frequencies were assessed via direct immunofluorescence staining and flow cytometry, oxLDL as well as IgM autoantibodies to oxLDL were measured with commercial kits. Results. We observed higher values of Treg in patients without carotid atherosclerosis. Patients with intact carotid arteries as compared to patients with mild atherosclerotic plaques had decreased Th1 levels. OxLDL IgM levels were higher in patients with intact carotid arteries. Patients who received statin treatment had higher levels of Treg. Immunophenotyping of B cells revealed two cases of monoclonal B-cell lymphocytosis and 1 case of B-CLL (B-cell chronic lymphocytic leukemia) in elderly patients with intact carotid arteries. Conclusion. We hypothesize that certain parameters of cell immunity may hamper atherosclerosis while protecting from lymphoproliferative disorders.
Źródło:
OncoReview; 2016, 6, 1; A29-36
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Primary cutaneous B-cell lymphoma located on the face and hard palate
Autorzy:
Brzeziński, Piotr
Chiriac, Anca
Budurca, Radu
Chiriac, Anca E.
Pinteala, Tudor
Ivan, Luminita
Foia, Liliana
Powiązania:
https://bibliotekanauki.pl/articles/1065379.pdf
Data publikacji:
2014
Wydawca:
Medical Education
Tematy:
B-cell lymphoma
face and hard palate lymphoma
non-Hodgkin lymphoma
Opis:
Introduction: Primary cutaneous B-cell lymphomas represent primary cutaneous lymphomas. The World Health Organization-European Organization for Research and Treatment of Cancer defines primary cutaneous B-cell limphomas as malignant lymphomas that are confined to the skin at presentation after complete staging procedures. Case report: We report a case of a woman with a cutaneous nodular B-cell lymphoma of the face, with very slow evolution that could easily be misdiagnosed. The patient had two non-ulcerated nodules on the left part of the face. A histological examination on both pieces following surgical excision showed a diffuse infiltrate of atypical B cells. The patient was subsequently directed to the Oncology Department for further investigation, but she died 24 hours afterwards due to one of the acute possible complications of the disease: pulmonary embolism. Conclusion: Cutaneous B-cell lymphoma is an unusual and rare skin neoplasm with a great range of clinical presentations and this is an alarm sign for apparent common skin lesion.
Źródło:
OncoReview; 2014, 4, 3; A113-116
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Quality of life patients treated with rituximab intravenous vs. subcutaneous in B-cell lymphomas: results from outpatient Hematooncology Clinic in Lodz
Autorzy:
Witkowska, Magdalena
Witkowska, Sonia
Klimczak, Marika
Frydecka, Anna
Witkowski, Michał
Smolewski, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/2047211.pdf
Data publikacji:
2021-07-14
Wydawca:
Medical Education
Tematy:
Rituximab
quality of life
anti CD20
B-cell NHL
lymphoma
Opis:
Introduction: Nowadays, rituximab is available both as intravenous (IV) and subcutaneous (SC) formulations. The aim of this study is to compare quality of life (QOL) of patients treated in Hematooncology Clinic in Lodz with B-cell nonHodgkin lymphoma (B-NHL) treated with rituximab IV and SC. Material and Methods: In 50 adult patients with B-NHL diagnosis we assessed QOL by three different questionnaries (EORTC QLQ-C30, FACT/ GOG-NTx and EQ-5D). We compared it between patients treated with rituximab IV and SC. Results: In comparison of general condition in EQ-5D-3L and EORTC QLQ-C30 questionnaire patients treated with rituximab SC felt statistically better than with IV administration (p<0.01). In SC group general health was evaluated for 72 while in IV for only 58,1. According to FACT/GOG-NTx questionnaire SC group had significantly better physical well-being. In SC group we observed statistically more complete responses (CR) 21 (88%) versus 17 (65%) in IV group. Moreover, trend was observed in emotional well-being in favor of SC treatment. Discussion: In our study we observed for the first time in the literature statistical difference in frequency of vomiting, nausea, and lack of appetite mentioned from our patients in questionnarie. It is very important that this findings were not published in any other study comparing SC and IV route od administration. Also looking at economic side of SC administration, this type of dosing. As a result it should be preferred form for B-cell lymphoma patients.
Źródło:
OncoReview; 2021, 11, 2; 33-39
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Invasive pulmonary aspergillosis in a child with acute myeloid leukaemia: pharmacotherapy and surgical management
Autorzy:
Styczyński, Jan
Powiązania:
https://bibliotekanauki.pl/articles/1064789.pdf
Data publikacji:
2016
Wydawca:
Medical Education
Tematy:
amphotericin B lipid form
chemotherapy
haematopoietic stem cell transplantation
invasive fungal disease
invasive fungal infection
pulmonary aspergillosis
Opis:
This paper reports on diagnostic and therapeutic management of pulmonary invasive fungal disease (IFD) in a child with relapsed acute myeloid leukaemia, undergoing chemotherapy followed by haematopoietic stem cell transplantation. Surgical management with resection of the involved lung tissue was based on the location of fungal infiltrates close to large circulatory vessels. After examination of resected pulmonary tissue, a diagnosis of proven IFD was done. This case report is an example that aspergillosis is usually the cause for pulmonary IFD. Pharmacotherapy of pulmonary IFD should be based on compounds with good penetration to lung tissue: amphotericin B lipid form or voriconazole.
Źródło:
OncoReview; 2016, 6, 4; A169-174
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pneumonia in patients after hematopoietic stem cell transplantation
Autorzy:
Styczyński, Jan
Powiązania:
https://bibliotekanauki.pl/articles/1062942.pdf
Data publikacji:
2017
Wydawca:
Medical Education
Tematy:
amphotericin B lipid complex
chemotherapy
hematopoietic stem cell transplantation
invasive fungal disease
invasive fungal infection
pneumonia
pulmonary aspergillosis
Opis:
Pneumonia is one of the most frequent cause of death after hematopoietic stem cell transplantation (HSCT). The objective of this review is to present various aspects of pneumonia in this group of patients, with focus on invasive pulmonary aspergillosis and cytomegalovirus disease, being the most frequent etiological causes of pneumonia after HSCT. The review is aimed at practical approach to diagnostic and therapeutic management of pneumonia after HSCT with special attention to: definitions of infections and level of diagnosis of upper and lower respiratory tract infections, including issues specific for invasive fungal disease, pneumocystosis, cytomegalovirus disease, community acquired respiratory viral infections and bacterial pneumonia. Another topics analyzed in the review are: epidemiology and risk factors for development of infection and risk of death due to pneumonia; invasive and non-invasive diagnostics, including imaging and laboratory biomarkers; methods of pharmacological and environmental prophylaxis and specific targeted therapy of pneumonia after HSCT.
Źródło:
OncoReview; 2017, 7, 3; 126-138
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-5 z 5

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