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Wyświetlanie 1-15 z 87
Tytuł:
Pharmacological profile of three different gamma-butyrolactone derivatives in mice
Autorzy:
Salat, K.
Librowski, T.
Filipek, B.
Powiązania:
https://bibliotekanauki.pl/articles/3034.pdf
Data publikacji:
2010
Wydawca:
Instytut Medycyny Wsi
Tematy:
pharmacological profile
gamma-butyrolactone derivative
mice
mouse
hot plate
capsaicin
toxicity
Źródło:
Journal of Pre-Clinical and Clinical Research; 2010, 04, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Clinical factors affecting the perception of hypoglycemia in type 1 diabetes patients treated with personal insulin pumps
Autorzy:
Matejko, B.
Grzanka, M.
Kiec-Wilk, B.
Malecki, M.T.
Klupa, T.
Powiązania:
https://bibliotekanauki.pl/articles/52037.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction and Objective. The ability to perceive the symptoms of hypoglycemia during the early decrease in plasma glucose concentration may be critical for the safety of T1DM patients treated with intensive insulin therapy, including those treated with continuous subcutaneous insulin infusion (CSII). In the presented observational study an attempt was made to asses clinical factors that might affect subjective awareness of hypoglycemia in CSII-treated T1DM patients, with special attention to factors specific for this mode of treatment. Materials and Methods. For the purpose of the study, data of 110 CSII-treated T1DM patients were collected (78 females and 32 males). The records were analyzed from glucose meters (200-300 measurements/download, depending on meter type) and insulin pumps (total insulin dose, basal/bolus ratio, number of boluses/day, bolus calculator and dual wave/square bolus usage, continuous glucose monitoring data) from the last 3 years. Results. It was found that the level of subjective hypoglycemia perception inversely correlated with the number of hypoglycemic episodes per 100 measurements, age, duration of diabetes, time on insulin pump, and positively correlated with mean glycemia (n = 98; r = 0.22; p = 0.0286). With respect to CSII-related factors, hypoglycemia perception inversely correlated with the percentage of basal insulin (n = 106; r = -0.20; p = 0.0354). In stepwise regression analysis, independent predictors for impaired hypoglycemia perception were: age β = -0.29 (p = 0.023), duration of diabetes β = -0.24 (p = 0.029) and number of the hypoglycemia episodes for 100 measurements β = -0.33 (p = 0.0005). Conclusions. Risk factors for impaired hypoglycemia perception in CSII-treated patients include those identified previously for the general population of T1DM individuals. In addition, the presented results suggest that a higher basal/bolus ratio may lead to impairment of the ability to perceive early symptoms of hypoglycemia.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wiedza i zachowania zdrowotne studentów medycyny w zakresie czynników ryzyka sercowo-naczyniowego
Knowledge of cardiovascular risk factors and health promoting behaviours among students of medicine
Autorzy:
Slusarska, B.
Kulik, T.B.
Piasecka, H.
Pacian, A.
Powiązania:
https://bibliotekanauki.pl/articles/4592.pdf
Data publikacji:
2012
Wydawca:
Instytut Medycyny Wsi
Źródło:
Medycyna Ogólna i Nauki o Zdrowiu; 2012, 18(47), 1
2083-4543
Pojawia się w:
Medycyna Ogólna i Nauki o Zdrowiu
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The importance of BMI in early prevention of cardiovascular risk in young adult Poles
Autorzy:
Slusarska, B.
Krzyszycha, R.
Zarzycka, D.
Kulik, T.B.
Dobrowolska, B.
Brzozowska, A.
Powiązania:
https://bibliotekanauki.pl/articles/3424.pdf
Data publikacji:
2012
Wydawca:
Instytut Medycyny Wsi
Źródło:
Journal of Pre-Clinical and Clinical Research; 2012, 06, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antimicrobial resistant and virulence genes profiles of some Gram-negative bacteria from clinical isolates at Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
Autorzy:
Nuhu, T.
Beng, E.O.B.
Bolaji, R.O.
Olayinka, T.A.
Olayinka, B.O.
Yahaya, M.
Powiązania:
https://bibliotekanauki.pl/articles/2097833.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
virulence factors
Enterobacteriaceae
anti-microbial resistance
north-west Nigeria
Opis:
Introduction and objective. Infections due to multidrug-resistant (MDR) Enterobacteriaceae are an ongoing global threat in their management. The aim of the study was to investigate the antiimicrobial resistance (AMR) and virulence gene profiles of MDR Gram-negative isolates in Sokoto, north-west Nigeria. Materials and method. A total of 578 clinical samples were collected from patients. Suspected Gram-negative bacteria were isolated from these clinical samples: vaginal swab, pus, stool, blood, wound swab and urine, using Gram-staining and conventional biochemical reactions. These isolates were further identified with an identification kit (Microgen-GN-A), and tested against a panel of 11 antibiotics. A single polymerase chain reaction (PCR) assay targeting 13 virulence gene related to adhesion (fimH, papC, and sfaS), iron chelation (iutA, and fyuA), toxins (astA, stx1, stx2, and eaeA), biofilm (bssS), and serum resistance (traT, iss, and kapsMTII) encoding genes were evaluated. Results. A total of 276 Gram-negative isolates were identified using the Gram stain and biochemical reactions. These organisms were further confirmed with identification kit. Of the 276 isolates, 36 organisms of interest (23 Escherichia coli, 4 Klebsiella pneumoniae and 9 Proteus mirabilis) were identified. Other Gram-negative isolates accounted for the remaining 86.9%. The majority of the isolates were resistant to cefixime (100%) and partially resistant to amikacin (19.4%).The virulence genes bssS (58.3%), fimH (44.4%), and iutA (44.4%) were the most prevalent, whereas kapsMTII (5.6%) and stx2 (2.8%) were least detected, while astA was not detected in any of the isolates. Conclusion. The study elucidated the prevalence of antibiotic resistance and virulence genes in Gram-negative bacteria from clinical isolates in Sokoto, north-western Nigeria. The majority of the isolates were MDR, thereby posing a public health risk.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2020, 14, 2; 52-57
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Care concept in medical and nursing students’ descriptions-Philosophical approach and implications for medical education
Autorzy:
Dobrowolska, B.
Slusarska, B.
Zarzycka, D.
McGonagle, J.
Pawlikowski, J.
Cuber, T.
Powiązania:
https://bibliotekanauki.pl/articles/51340.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2014, 21, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Psychosocial factors and health status of employees at the Poznan University of Medical Sciences
Autorzy:
Ziemska, B.
Klimberg, A.
Marcinkowski, J.T.
Powiązania:
https://bibliotekanauki.pl/articles/49911.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction: New opportunities in the labour market, competition in services and globalization have contributed to the increase in load factors in the psychosocial work environment. Availability, readiness to help, work with the sick, the suffering patient – night shifts, overtime, workaholic (as a new form of addiction), and bullying – are becoming more pronounced causes of stress, fatigue and burnout in medicine. Thus, difficult working conditions are largely the cause of unhealthy lifestyles in the medical professions and foster the development of various types of addiction and physical illness. The negative effects of psychosocial factors – in the form of immune disorders, increased incidence of mental and somatic diseases, and metabolic and hormonal disorders – more often cause increase absence through sickness and the shortening of working life. Objective: The main aim of the presented study was to provide results concerning the health state of employees of the Poznan University of Medical Sciences (PUMS), and also to analyze relations between selected psychosocial risks factors and the state of health of PUMS employees. Material and methods: The results of research conducted in 2009–2010 which covered 2,468 employees of the PUMS and the results of studies using an anonymous own questionnaire survey, evaluating exposure to psychosocial factors, which included the 1,096th members of staff of the PUMS. Results: There was a clear effect of psychosocial risk factors for health workers. The greatest burden of these factors was observed among workers with higher education, mostly doctors. This occupational group also worked in several places of work more often than other employees of the university. These workers often complained of chronic fatigue, recurrent respiratory infections, hypertension, sleep disorders, neurotic disorders and depression. The complaints quite often diagnosed were immune disease, allergies, skin diseases, gastrointestinal diseases, and disorders of carbohydrate and lipid metabolism, which clearly intensified under stress. The clearest negative impact of psychosocial factors on the health of the workers were observed in those a with higher education, employed at several jobs, and complained about poor work organization. Conclusions: 1) It is necessary to implement prevention programs for the staff of the PUMS, aimed at the primary and secondary negative impact of psychosocial factors. 2) Psychological counseling is advisable for employees. 3) It is essential that the issue of voice training, and interpersonal communication techniques to teach and control the schedule of classes, in order to reduce the workload, and encourage physical activity and other forms of relaxation. 4) It is advisable to periodically check on the work conditions and organization of work to help eliminate stressors in the work environment.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Past obstetric history and risk of ovarian cancer
Autorzy:
Pieta, B.
Chmaj-Wierzchowska, K.
Opala, T.
Powiązania:
https://bibliotekanauki.pl/articles/50632.pdf
Data publikacji:
2012
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction: Early age at menarche and late age at last menstrual period, as well as other reproductive factors, may be the cause of development of some types of cancer concerning the female reproductive organs. It has been estimated that late menopause may be responsible for the occurrence of even 16% of cases of ovarian cancer in the population. The incidence of ovarian cancer is also higher among nulliparous women, and among those who rarely become pregnant. Objective: The objective of the study was analysis of the effect of reproductive factors on the risk of ovarian cancer. Methodology: The study covered healthy women, without the diagnosis of focal lesions in the ovaries, and women with the diagnosis of ovarian cancer. The study was conducted during the period from September 2007 – November 2011, and covered a total number of 1,346 women. Odds ratio was calculated for individual risk factors. Statistical analysis was performed by means of the statistical packages STATISTICA v8, GrafPad Instat v 3.00, Analyse-it v. 2.2, and Cytel Studio StatXact-8. Statistical hypothesis were verified on the level of significance p ≤ 0.05. Results: Among females who began menstruating by the age of 11, the risk of ovarian cancer was 1.6 higher than among those in whom the first period occurred at the age of over 13. Similarly, among women who menstruated at the age of over 55 the risk of development of ovarian cancer was 1.4 times higher. The age at which a woman delivered her first live baby is also of importance. In the group of women who gave birth at the age of over 35, the risk was elevated and remained on the level of OR=1.7; 95%CI 0.66-4.5, compared to those who bore the first baby under the age of 25. If the pregnancy was terminated with miscarriage, the risk of contracting ovarian cancer decreases, and was on the level of OR=0.8; 95%CI 0.53-1.28, compared to the women who have never been pregnant. Among patients who did not breastfeed their babies, ovarian cancer risk was 1.7 times higher, compared to those breastfeeding. Conclusion: Reproductive factors exert a significant effect of the risk of development of ovarian cancer.
Źródło:
Annals of Agricultural and Environmental Medicine; 2012, 19, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Life style and risk of development of breast and ovarian cancer
Autorzy:
Pieta, B.
Chmaj-Wierzchowska, K.
Opala, T.
Powiązania:
https://bibliotekanauki.pl/articles/51430.pdf
Data publikacji:
2012
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction: Many risk factors may be monitored, and individual decisions concerning life style exert an effect on most factors associated with the development of cancer. It is estimated that the majority of malignant cancers, as much as 70%, are the result of the harmful effect of factors related with diet, life style, or those present in the surrounding environment. Objective: The objective of the study was analysis of selected factors related with life style and their effect on the risk of development of breast and ovarian cancer. Methodology: The study covered healthy women, without the diagnosis of focal lesions in the breast and ovaries, and women with the diagnosis of breast or ovarian cancer. The study was conducted during the period September 2007 – November 2011, and covered a total of 1,484 women aged 18-80. Odds ratio was calculated for individual risk factors. Statistical analysis was performed by means of the statistical packages STATISTICA v8, GrafPad Instat v 3.00, Analyse-it v. 2.2, and Cytel Studio StatXact-8. Statistical hypothesis were verified on the level of significance p ≤ 0.05. Results: Health-promoting life style related with physical activity and other health promoting behaviours, such as mode of nutrition, reduction or elimination of alcohol consumption and discontinuation of smoking considerably decrease the risk of development of malignant breast and ovarian cancer. The number and variety of factors which affect the risk of occurrence of cancerous diseases indicate that there is a need for monitoring of the hazard. Conclusion: It is necessary to carry out preventive actions which would cover the health education of women, concerning life style-related risk factors and methods of their modification.
Źródło:
Annals of Agricultural and Environmental Medicine; 2012, 19, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena zachowań prozdrowotnych dotyczących profilaktyki raka piersi u kobiet w makroregionie lubelskim
Evaluation of health promoting behaviours concerning breast cancer among women living in the Lublin Macroregion
Autorzy:
Suszynska, K.
Kulik, T.B.
Pacian, A.
Powiązania:
https://bibliotekanauki.pl/articles/4121.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Źródło:
Medycyna Ogólna i Nauki o Zdrowiu; 2013, 19(48), 3
2083-4543
Pojawia się w:
Medycyna Ogólna i Nauki o Zdrowiu
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prognostic factors in traumatic brain injury and their association with outcome
Autorzy:
Kulesza, B.
Nogalski, A.
Kulesza, T.
Prystupa, A.
Powiązania:
https://bibliotekanauki.pl/articles/3091.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Tematy:
prognostic factor
traumatic brain injury
outcome
prognosis
Opis:
Introduction. Traumatic brain injuries (TBI) are a real social problem, with an upward trend worldwide. TBI is the leading cause of death and disability, especially among young men. Each year in Europe, and also in Poland, 243 per 100,000 individuals suffer from TBI. Assessing prognosis after traumatic brain injury is very important in order to help clinicians to make a decision about the implementation of specific methods of treatment, and to make communication with the patient and the patient’s family easier. Objective. The objective of this review was to present prognostic factors, to assess outcomes within a short time after a moderate to severe traumatic brain injury, as well as to predict functional outcome. The most important independent variables were: age, Glasgow Coma Scale (GCS) motor score, pupil response, Marshall CT classification and traumatic subarachnoid haemorrhage. Other important prognostic factors included hypotension, hypoxia, glucose, coagulopathy, haemoglobin and category of CT characteristic, such as midline shift, mass lesion, basal cistern. Conclusions. Gender and intraventricular haemorrhage did not have predictive value. This subject needs much more research in the area of new prognostic factors which would be better associated with outcome after traumatic brain injury.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2015, 09, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mercury cycling in the terrestrial, aquatic and atmospheric environment of the Slovak Republic - an overview
Autorzy:
Kimakova, T.
Nasser, B.
Issa, M.
Uher, I.
Powiązania:
https://bibliotekanauki.pl/articles/2083139.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
mercury
incinerators
landfill waste
crematoria
soils
water
Opis:
Introduction. Mercury release in the environment is mainly the result of human activity, particularly from coal-fired power stations, residential heating systems, waste incinerators, and as a result of mining for mercury, gold and other metals, which have led to widespread global mercury pollution. Excessive exposure to mercury is associated with a wide range of adverse health effects, including damage to the central nervous system, digestive and immune systems, and to lungs, kidneys, skin and eyes. Objective. The main aim of the study is to summarize the selected mercury sources in the environment of the Slovak Republic, regarding waste incinerators, landfill waste, crematoria, chemical plants, rivers and soils. Brief description of state of knowledge. Although the neurologic symptoms of Minamata disease were identified sufficiently for specialists to classify mercury as the causative agent, the acceptance of mercury ́s environmental impacts will require several decades of research. Several new issues have arisen – the need for energy conservation leads to the use of fluorescent lighting, which contain mercury; emissions driven by increases in coal combustion, incineration and economic development have sent more mercury into the air, soil and water. Conclusions. Mercury is toxic to human health, posing a particular threat to the development of the child in utero and early in life. The systematic analytical controls of contaminants in water, soil and air are important. The installation of modern cleaning technologies to comply with the maximum emission level can substantially minimized the environmental impact of incinerators. Since human cremation is also an increasing practice, further research on mercury emissions is necessary.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 2; 273-279
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 87

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