- Tytuł:
-
Wybrane metody separacyjne i woltamperometryczne w analizie leków i substancji endogennych dla diagnostyki i terapii klinicznej
Selected separation and voltammetric methods in the analysis of drugs and endogenous substances for diagnostics and clinical therapy - Autorzy:
-
Baranowska, Irena
Bajkacz, Sylwia
Markowski, Piotr
Płonka, Joanna - Powiązania:
- https://bibliotekanauki.pl/articles/1413240.pdf
- Data publikacji:
- 2021
- Wydawca:
- Polskie Towarzystwo Chemiczne
- Tematy:
-
chromatografia
woltamperometria
leki
aminy biogenne
ekstrakcja
spektrometria
chromatography
voltammetry
drugs
biogenic amines
extraction
spectrometry - Opis:
- The developed chromatographic methods (HPLC and UHPLC/UV, DAD, FL, ED, MS-MS and GC-MS), for the determination of drugs from different therapeutic groups in body fluids, have been presented. Drugs were determined alongside their metabolites, in different concentration ranges, usually after a removal of the interferences from the biological material matrix. Extraction procedures, like LLE, SPE, MEPS, SALLE, USAEME, have been developed for the separation of analytes. Methods for the determination of endogenous compounds: L-camitine, L-arginine and their metabolites, dopamine and its metabolites, and other compounds resulting from their metabolism have also been developed. Cyclic voltammetry and differential pulse voltammetry methods for the determination of electrochemically active drugs have also been presented. Such methods can be used to verify the results of chromatographic determinations. This article presents the results of the research included in 35 publications from the JCR list.
- Źródło:
-
Wiadomości Chemiczne; 2021, 75, 7-8; 869-892
0043-5104
2300-0295 - Pojawia się w:
- Wiadomości Chemiczne
- Dostawca treści:
- Biblioteka Nauki
Artykuł