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    Wyświetlanie 1-7 z 7
    Tytuł:
    The Chemical Study of Calotropis
    Autorzy:
    Verma, V. N.
    Powiązania:
    https://bibliotekanauki.pl/articles/412601.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Calotropis
    Madar
    AAS
    metals
    Opis:
    Calotropis (Asclepiadaceae) commonly known as “madar” is a useful medicinal plant. The two species i.e. Calotropis gigantea and Calotropis procera are to a great extent having a very similar chemical properties, but the colours of their flowers are different. The pH of latex of these two species has been found different in the present study. The temperature effects have been noticed on their pH values which is varying from 7.2 to 8.1 between the temperatures 25 °C to 45 °C and then remains constant for Calotropis gigantia. The milky latex contains hydrocarbons, fatty acids, sterols and terpenels. Seven spots have been observed on the TLC plates; out of which 3 were identified as calotoxin, uscharin and calactin. Aluminum, calcium, cadmiun, cobalt, chromium, copper, iron, magnese, magnesium, nickel, lead, and zinc metal elements were investigated in the latex and similarly in the leaves and bark from the AA spectra. The amount of magnese was found the highest in the latex of both species but calcium was found highest in leaves and bark of both species. Copper, chromium and lead were not found at all in latex but a very little amount of copper and lead were found in leaves and bark. The atomic absorption spectrophotometer was used to investigate the metals which were measured in the order of ppm.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 1; 74-90
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of flame atomic absorption spectrometry in food biotechnology, Momordica charantia lin
    Autorzy:
    Verma, V.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/11866.pdf
    Data publikacji:
    2015
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Opis:
    Momordica charactia lin( Bitter melon) has been the interest of many studies by researchers for a long time due to its very interesting human beneficial properties. It belongs to cucurbitacea family and momordica genus. It is used by human consumption all over the world in different forms such as a vegetable and /or medicine. The researchers have concentrated on the studies on its fruits and some times on its seeds and leaves. The present study is an extensive investigation of the quantitative elements such as Ca, Cd ,Co, Cr, Cu, Fe, Mg, Mn, Pb, Zn, K, N, and P of the fruit- skin, fruit-flesh, fruit-seed, tissue skin, leaf and root of the momordica charantia lin using flame atomic absorption spectrometry. The result shows a quite good variation of the concentration of the elements in different part of the plant.
    Źródło:
    International Letters of Natural Sciences; 2015, 40
    2300-9675
    Pojawia się w:
    International Letters of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Photochemical studies of Eichhornia crassipes (Water Hyacinth)
    Autorzy:
    Ratan, A.
    Verma, V. N.
    Powiązania:
    https://bibliotekanauki.pl/articles/412466.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Water Hyacinth
    Eichhornia crassipes
    AAS
    Elements
    metals
    Opis:
    Eichhornia crassipes is a floating macrophyte. It is capable of assimilating large quantities of toxic metals, some of which are essential for plant growth. Water Hyacinth grows rapidly in water with a high level of nutrients like nitrogen and phosphorous. The plants have been shown to absorb trace elements such as Silver (Ag), Lead (Pb), Cadmium (Cd) and Copper (Cu) reported by Lu et al [1]. The purpose of this study is to determine the distribution of heavy metals in different parts of the Water Hyacinth . Such a detail study has been taken for the first time. It is expected that the metal distribution within the plant species would be a representation of the concentration and distribution of the water in which it is found. Plants have the ability to accumulate non-essential and essential trace elements and this ability could be harnessed to remove pollutant metals from the environment. Aluminum, cadmium, calcium, copper, iron, lead, magnesium and zinc have been found in different amounts in roots, stems , leaves and flowers.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 11, 3; 214-222
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Photochemical Studies of Solanum Melangena (Eggplant) Fruit by Flame Atomic Absorption Spectrometry
    Autorzy:
    Persid, R.
    Verma, V. N.
    Powiązania:
    https://bibliotekanauki.pl/articles/411552.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    solanum melangena
    Eggplant
    elemental analysis
    AAS
    Opis:
    Solanum melangena (eggplant) belongs to Solanaceae family. The common name of this frui and the plant is the same. It has different names in different countries such as eggplant, brinjal, baigan, balangie etc. Eggplant has been reported as a healthiest fruit due to the chemical constituents. The shape, size and colour of the fruits are also different. The genetically engineered eggfruits are also available. Some research works on eggplant are reported in different countries for different purposes. The present study has been taken into an account for the chemical elements present in flesh, skin and the seeds of eggplant grown in the soil and environmental conditions of Guyana. The investigation by the flame atomic absorption photometry shows the presence of Ca, Cd, Co, Cu, Fe, Mg, Mn, Pb and Zn at a varying concentrations in flesh, skin and seeds. In general the presence of calcium and magnesium as the higher values out of which concentration of calcium is 1366mg/kg in skin and magnesium as 2466 mg/Kg in seed.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 20, 2; 211-218
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Investigation of Nutrient Elements in Cucurbita pepo Using Atomic Absorption Spectrometry
    Autorzy:
    Harichan, S.
    Verma, V.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/411957.pdf
    Data publikacji:
    2013
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    AAS
    Cucurbita pepo
    metals
    Opis:
    There are a number of factors to keep our health in good condition. One of them is the role of the proper amount of nutrient metals which play the important role in many reactions in the body and it becomes increasingly evident that keeping a balance level of nutrient metals in every organ is very important for maintaining a healthy body, although metals comprise only a fraction of total body weight (mg). They play crucial role for many body functions in the metabolic regulations of the human body including transporting oxygen, normalizing the nervous system. The present investigation is focused to find out the different nutrient metals that exist in the vegetable Cucurbita pepo (squash) a source of natural nutrient metals abandance and to determine the relative concentration of each metal element. Investigation has been performed on the skin, the flesh, the seed, the leaves, the stems and the roots of squash to determine the relative levels of concentrations of various metals such as elements such as Al, Ca, Cd, Co,Cr, Fe,K, Mg, Mn, Na, Ni, Pb and Zn. The Atomic Absorption Spectrometry technique is used. The proper vegetable consumption can improve the mineral and trace metal regulation and reduce cardiovascular diseases and certain cancer risks.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2013, 2; 11-17
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Spectroscopic Investigation of the Hair of Diabetic Patients
    Autorzy:
    Ali, A.
    Verma, N.V.
    Powiązania:
    https://bibliotekanauki.pl/articles/412256.pdf
    Data publikacji:
    2013
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    diabetes
    metals
    hair
    AAS
    Opis:
    Diabetes is a major disease condition that is accountable for 5% of annual cause of death globally and it continues to escalate. In this research the levels of minerals in persons with type 2 diabetes were investigated using hair as the biopsy specimen. The philosophy behind is that minerals are involved in countless metabolic functions in all phases of the life process, an imbalance of which can have widespread implication, while hair due to its physiology serves an invaluable record of the body's exposure to minerals. Hair metal testing is a fascinating new diagnostic tool and often gives unexpected clues to mineral imbalances in the body. In executing the research samples of head hair collected from 6 type 2 diabetic patients were washed to remove exogenous contaminants, then subjected to open vessel acid digestion and subsequent analysis for the elements Ca, Cd, Cr, Cu Fe, K, Mg, Na and Zn using Flame Atomic Absorption Spectroscopy (FLAAS). After comparing the concentration of the elements to a range that is considered to be normal it was found that Ca, Zn, Fe, Mg, K, Cu, Cd and Cr were off range while Na was normal. Upon investigating the function and effects of the elements that were off range it was found that a deficiency of chromium and an excess of iron could be a possible cause of diabetes.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2013, 3; 37-45
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Drummondin E and Flinderole B are potential inhibitors of RNA-dependent RNA polymerase of SARS-CoV-2: an in silico study
    Autorzy:
    Akhtar, N.
    Verma, H.
    Silkari, O.M.
    Upadhyay, A.K.
    Kaushik, V.
    Mannan, M.A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2096249.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    RNA polymerase
    SARS-CoV-2
    RNA-dependent
    Drummondin E
    Flinderole B
    Opis:
    Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected 235.6 million people worldwide. In the present study, RNA-dependent RNA polymerase (RdRp) (PDB Id: 6M71) of SARS-CoV-2, an essential enzyme needed for subgenomic replication and amplification of RNA, was selected. Similar to other RdRps, it is a conserved protein and a popular target for antiviral drug therapy. Based on a computational approach, potential RdRp inhibitors were identified. The absorption, distribution, metabolism, excretion, and toxicity (ADMET) of selected molecules were determined using computation tools. The potential inhibitors were docked to the RdRp and later confirmed by Molecular Dynamics (MD) using the “Flare” module of Cresset software. Drummondin E and Flinderole B had higher drug similarity scores among the compounds selected in this study. Both these compounds are noncarcinogenic, nonirritant, nontumorigenic, and nonmutagenic. Molecular docking studies showed that both compounds can bind to RdRp. The best ligand interaction patterns were validated by MD using the “Flare” module. MD was performed for the period of 100 ns with the time step of 1 fs. The simulation results suggest that Thr-680, Arg-624, Lys-676, and Val-557 are key interacting partners in the Drummondin E-RdRp complex, while Asp-618, Asp-760, Asp-623, Arg-624, and Asp-761 are the interacting partners in the Flinderole B-RdRp complex. Based on the in silico drug-likeness score; ADMET properties; and molecular simulation result, we surmise that Flinderole B and Drummondin E could impede SARS-CoV-2 genome replication and transcription by targeting the RdRp protein.
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2022, 103, 1; 53-70
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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