Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "neuropathy" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-15 z 28
Tytuł:
Neuropatia cukrzycowa u dzieci i dorosłych z cukrzycą typu I - diagnostyka, leczenie
Diabetic neuropathy in children and adult with type I diabetes – diagnosis and management
Autorzy:
Stańczyk, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/1059266.pdf
Data publikacji:
2007
Wydawca:
Medical Communications
Tematy:
autonomic neuropathy
diabetic neuropathy
diagnosis of neuropathy
management of neuropathy
peripheral neuropathy
type I diabetes mellitus
neuropatia cukrzycowa
neuropatia obwodowa
neuropatia autonomiczna
rozpoznawanie neuropatii
leczenie neuropatii
cukrzyca typu I
Opis:
Diabetic neuropathy is one of the most common and serious complications of diabetes both type I and type II. In type I diabetes mellitus neuropathy usually assumes form of a distal symmetric polyneuropathy (DPN) and/or a diabetic autonomic neuropathy (DAN). Other forms as acute sensory neuropathy, cranial neuropathy, truncal radiculoneuropathy or proximal motor neuropathy are present sporadically in patients with type I diabetes. Damage to nerves in the abnormal environment of diabetes mellitus leads to diabetic neuropathy. There are three hypotheses that explain the pathogenetic mechanism of polyneuropathy: metabolic, vascular and immunological. Many diabetic patients have demonstrable abnormalities of autonomic function without any evidence of clinical disease. Tests of autonomic function and tests of conduction veloautocity in peripheral nerves are assumed to be a measure of neurological state and may be important methods of assessing therapy of diabetic complications. Control of hyperglycaemia is the basis of the adequate management. α-liponic acid is used due to some evidences suggesting the role of free radicals in pathogenesis diabetic neuropathy. Antiepileptics and antidepressants inhibiting selective norepinephrine and serotonin reuptake are administered for pain control in symptomatic management.
Neuropatia cukrzycowa jest jednym z najczęściej występujących poważnych powikłań w cukrzycy zarówno typu I, jak i typu II. W cukrzycy typu I zwykle występują obwodowa symetryczna polineuropatia (DPN) i/lub cukrzycowa neuropatia autonomiczna (DAN). Inne formy, takie jak ostra czuciowa neuropatia, neuropatia czaszkowa, radikulopatia tułowia, neuropatia ruchowa proksymalna, u pacjentów z cukrzycą typu I występują rzadziej. Uszkodzenie włókien w przebiegu cukrzycy prowadzi do wystąpienia neuropatii. Wysuwane są trzy hipotezy dotyczące mechanizmów prowadzących do neuropatii cukrzycowej: metaboliczna, naczyniowa i immunologiczna. U wielu chorych występują nieprawidłowości w funkcjonowaniu układu autonomicznego bez wyraźnych klinicznych objawów choroby. Wykonywanie testów czynności układu autonomicznego i testów oceniających przewodnictwo w nerwach obwodowych jest ważne dla oceny stanu neurologicznego i dla decyzji terapeutycznych w przypadku powikłań cukrzycowych. Kontrola hiperglikemii jest podstawą adekwatnego leczenia neuropatii cukrzycowej. Kwas α-liponowy jest stosowany w związku z uzasadnionymi sugestiami udziału wolnych rodników tlenowych w patogenezie neuropatii cukrzycowej. Leki przeciw-drgawkowe i antydepresyjne hamujące zwrotny wychwyt noradrenaliny lub serotoniny są stosowane dla łagodzenia dolegliwości bólowych.
Źródło:
Aktualności Neurologiczne; 2007, 7, 3; 202-209
1641-9227
2451-0696
Pojawia się w:
Aktualności Neurologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of RAGE in the diabetic neuropathy
Autorzy:
Juranek, Judyta
Banach, Marta
Powiązania:
https://bibliotekanauki.pl/articles/552293.pdf
Data publikacji:
2015
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
diabetic neuropathy
neurodegeneration
RAGE
Źródło:
Family Medicine & Primary Care Review; 2015, 4; 316-318
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A 16-year-old patient with Charcot Marie Tooth disease in variant c.217G>C of the INF2 gene and focal glomerulosclerosis – a case report
Autorzy:
Przygoda, Maria
Matias, Dawid
Jurczak, Maciej
Sokołowska, Aldona
Raba, Karolina
Wołkanowski, Juliusz
Rydzanicz, Małgorzata
Kosińska, Joanna
Płoski, Rafał
Aebisher, David
Pyrkosz, Antoni
Powiązania:
https://bibliotekanauki.pl/articles/2040499.pdf
Data publikacji:
2021-12-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
exome sequencing
neuropathy
nephropathy
Opis:
Introduction. Charcot Marie Tooth disease (CMT) is currently one of the most commonly diagnosed and commonly hereditary sensorimotor neuropathies. Concluding from the literature, this is the first study describing the case of a patient with CMT disease in the c.217G> C variant of the INF2 gene and focal segmental glomerulosclerosis. Aim. To present a case of a 16-year-old patient suffering from CMT disease in variant c.217G> C of the INF2 gene and focal glomerulosclerosis. Description of the case. The text describes the CMT disease in a patient who underwent the WES / WGS-NGS genetic test and found a mutation within the INF2 gene at the chromosomal position hg38 14: 104701582-G> C, cDNA level c.217 G> C , notation at the p protein level (Gly73Arg). Genotype record according to Human Genome Variation Society: NM_022489.4: c. [217G> C]; [217 =]. The publication includes data on genetics, molecular mechanisms of the disease, diagnostic methods, rehabilitation and surgical treatment. Conclusion. CMT disease is a heterogeneous group of diseases caused by mutations in various genes. The incidence of this pathology has increased significantly in the last century. Currently, there are no treatments available to combat this disease, and symptomatic treatment is the only treatment available.
Źródło:
European Journal of Clinical and Experimental Medicine; 2021, 4; 341-346
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A newly identified Thr99fsX110 mutation in the PMP22 gene associated with an atypical phenotype of the hereditary neuropathy with liability to pressure palsies
Autorzy:
Moszyńska, Izabela
Kabzińska, Dagmara
Sinkiewicz-Darol, Elena
Kochański, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1040475.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
HNPP neuropathy
PMP22 gene mutations
Opis:
Hereditary neuropathy with liability to pressure palsies (HNPP) is manifested by a spectrum of phenotypes, from the classical HNPP course associated with intermittent nerve palsies to a neuropathy resembling Charcot-Marie-Tooth type 1 (CMT1) disease. The majority of HNPP cases are associated with submicroscopical deletions in the 17p11.2-p12 region containing the PMP22 gene, while PMP22 point mutations are rare, representing about 15% of HNPP cases. In this study, we present a patient manifesting with atypical HNPP phenotype associated with a new Thr99fsX110 mutation in the PMP22 gene. We conclude that all patients who fulfill the electrophysiological criteria of HNPP, even if they lack the typical HNPP phenotype, should be tested for point mutations in the PMP22 gene.
Źródło:
Acta Biochimica Polonica; 2009, 56, 4; 627-630
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Idebenone – a new drug for patients with Lebers hereditary optic neuropathy
Idebenon – nowy lek dla pacjentów z dziedziczną neuropatią wzrokową Lebera
Autorzy:
Szumny, Dorota
Czajor, Karolina
Mulak, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/1927971.pdf
Data publikacji:
2021
Wydawca:
Medical Education
Tematy:
LHON
Leber hereditary optic neuropathy
idebenone
Opis:
Leber's Hereditary Optic Neuropathy is a rare disease caused by a mutation in the mitochondrial DNA. It appears most often in young men, leading to profound, permanent loss of vision in a short time. There is no specific treatment for this condition. Idebenone is a medicine that administered to patients with Leber's hereditary optic neuropathy improves or stops the deterioration of vision. Increasing the number of people during therapy and the duration of treatment will allow in the future to answer the question, whether this drug is effective and safe in a larger group of patients.
Dziedziczna neuropatia wzrokowa Lebera jest rzadką chorobą wywoływaną mutacją w mitochondrialnym DNA. Najczęściej ujawnia się u młodych mężczyzn i w krótkim czasie prowadzi do głębokiej, trwałej utraty wzroku. Do tej pory brakuje specyficznego leczenia tego schorzenia. Podawanie idebenonu pacjentom z dziedziczną neuropatią wzrokową Lebera powoduje poprawę lub zahamowanie pogorszenia widzenia. Zwiększenie liczby osób w trakcie terapii oraz czasu prowadzonego leczenia pozwoli w przyszłości odpowiedzieć na pytanie, czy lek ten jest skuteczny i bezpieczny dla większej grupy pacjentów.
Źródło:
OphthaTherapy; 2021, 8, 1; 32-36
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A novel homozygous mutation in the WNK1/HSN2 gene causing hereditary sensory neuropathy type 2
Autorzy:
Potulska-Chromik, Anna
Kabzińska, Dagmara
Lipowska, Marta
Kostera-Pruszczyk, Anna
Kochański, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1039722.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
hereditary
autonomic
sympathetic skin response
sensory neuropathy
mutation
Opis:
Hereditary sensory and autonomic neuropathy type 2 is a rare disorder caused by recessive mutations in the WNK1/HSN2 gene located on chromosome 12p13.33. Phenotype of the patients is characterized by severe sensory loss affecting all sensory modalities. We report a novel homozygous Lys179fsX182 (HSN2); Lys965fsX968 (WNK1/HSN2) mutation causing an early childhood onset hereditary sensory and autonomic neuropathy type 2, with acromutilations in upper and lower limbs, and autonomic dysfunction. To the best of our knowledge this is the first genetically proven case of hereditary sensory and autonomic neuropathy type 2 originating from East Europe.
Źródło:
Acta Biochimica Polonica; 2012, 59, 3; 413-415
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effectiveness of electrical stimulation and low-intensity laser therapy on diabetic neuropathy: A systematic review
Autorzy:
Adehunoluwa, Emmanuel A.
Adesina, Miracle A.
Adeulure, Taiwo G.
Akinfolarin, Yemi T.
Babatunde, Kazeem O.
Efunniyi, Adenike O.
Mamud, Olusola S.
Oyejola, Oluwatimilehin G.
Tiamiyu, Oluwaleke M.
Olajire, Tolulope I.
Powiązania:
https://bibliotekanauki.pl/articles/1077040.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Diabetes mellitus
diabetic neuropathy
electric stimulation
laser therapy
Opis:
Diabetes mellitus (DM) is a group of metabolic diseases which typically presents with frequent urination, increased thirst and increased hunger. DM be classified into three main types: type I (insulin-dependent DM), type-II (non-insulin dependent DM) and type III (gestational DM). Diabetes is a group of diseases of global health significance as 382 million people worldwide had diabetes in the year 2013 and this was projected to increase to an estimated 415 million in 2015. Damage to the nerves of the body (diabetic neuropathy) is the most common complication of diabetes. The signs and symptoms of diabetic neuropathy include numbness, diminished sensation, pain etc. Various types of electrotherapy, such as transcutaneous electrical nerve stimulation (TENS), pulsed-dose electrical stimulation, frequency-modulated electromagnetic neural stimulation, have been reported effective in managing diabetic neuropathy. This study is a systematic review of the evidence to enable the determination of the effectiveness of electrical stimulation and low-intensity laser therapy (LILT), and also aid their recommendation if proven to be effective. The outcome of this study was that TENS and other forms of electrical stimulation reviewed in this study may be effective and safe non-pharmacological treatment modalities in relieving the symptoms associated with diabetic neuropathy. The effectiveness of LILT couldn’t be determined due to the different parameters used to evaluate patients’ outcome and limited number of studies. Authors recommend that further randomized controlled trials with similar methodological parameters and studies with higher quality of evidences are needed to establish the true effectiveness of these modalities in diabetic neuropathy.
Źródło:
World News of Natural Sciences; 2019, 23; 110-127
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bruns-Garland syndrome in patient with long-term type 2 diabetes
Zespół Brunsa-Garlanda u pacjentki z wieloletnią cukrzycą typu 2
Autorzy:
Cichocka, Edyta
Widenka, Sabina
Gumprecht, Janusz
Powiązania:
https://bibliotekanauki.pl/articles/51616768.pdf
Data publikacji:
2024-10-09
Wydawca:
Śląski Uniwersytet Medyczny w Katowicach
Tematy:
diabetes
diabetic neuropathy
amyotrophy
cukrzyca
neuropatia cukrzycowa
amiotrofia
Opis:
The Bruns-Garland syndrome (diabetic amyotrophy) is a rare disorder that affects fewer than 1% of patients with diabetes. It is manifested by unilateral or bilateral pain, weakness and muscle wasting in the proximal part of the lower limbs (proximal motor neuropathy). We present a 72-year-old patient with long-term type 2 diabetes mellitus and with the Bruns-Garland syndrome. All the symptoms, including neurological manifestations, were reversible and resolved after the implementation of intensive treatment. Optimizing diabetes treatment, rehabilitation, pain management and the use of benfotiamine and alpha-lipoic acid preparations were crucial to accelerate the treatment effects of diabetic amyotrophy.
Zespół Brunsa-Garlanda (amiotrofia cukrzycowa) to rzadkie zaburzenie, które dotyka mniej niż 1% pacjentów chorujących na cukrzycę. Objawia się jednostronnym lub obustronnym bólem, osłabieniem i zanikiem mięśni w bliższej części kończyn dolnych (proksymalna neuropatia ruchowa). W prezentowanej pracy przedstawiono przypadek 72-letniej pacjentki z długotrwałą cukrzycą typu 2 i zespołem Brunsa-Garlanda. Wszystkie objawy, w tym objawy neurologiczne, były odwracalne i ustąpiły po wdrożeniu intensywnego leczenia. Optymalizacja leczenia cukrzycy, rehabilitacja, leczenie bólu oraz stosowanie preparatów benfotiaminy i kwasu alfa-liponowego miały kluczowe znaczenie dla przyspieszenia efektów leczenia amiotrofii cukrzycowej.
Źródło:
Annales Academiae Medicae Silesiensis; 2024, 78; 248-252
1734-025X
Pojawia się w:
Annales Academiae Medicae Silesiensis
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A cross-sectional study of the upper limb non-neurogenic physical findings in computer operators and their relation to pain and neurological findings
Autorzy:
Jepsen, Kasper R.
Thomsen, Gert F.
Jepsen, Jørgen R.
Powiązania:
https://bibliotekanauki.pl/articles/2095494.pdf
Data publikacji:
2021-09-03
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
pain
comorbidity
physical examination
computer operation
musculoskeletal disorders
neuropathy
Opis:
ObjectivesThe character of upper limb disorders in computer operators is subject to debate. While nerve involvement is suggested by the presenceof pain, paresthesia and subjective weakness, these symptoms are mainly interpreted as related to pathologies outside the nervous system. Findings in a previous study involving computer operators indicated peripheral nerve afflictions with specific locations in symptomatic subjects. Based on the same sample, this study addresses the relation of non-neurogenic findings to pain and neurological findings.Material and MethodsOverall, 96 computer operators scored their perceived pain in the neck, shoulder, elbow, and wrist/hand on a Visual Analogue Scale of 0–9. They underwent 2 sets of blinded physical examinations of selected non-neurogenic and neurological items, respectively. The authors analyzed correlations between the scores of each non-neuropathic finding, and a) mean pain scores for each and all regions, and b) scores for neurological patterns reflecting brachial plexopathy, median neuropathy (the elbow), and posterior interosseous neuropathy, respectively, and their combination. Kendall’s rank correlation test was applied for all statistical analyses.ResultsA median pain level of 1 or 0.5 was reported by 80 and 57 participants on the mouse-operating or contralateral side, respectively. Non-neurogenic and neurological findings were frequent. The mean overall pain correlated with palpation soreness of the neck insertions, and of the trapezius and supraspinatus muscles. Neck and elbow pain correlated with palpation soreness at the neck insertions and the lateral epicondyles, respectively. Significant correlations on the mouse-operating side were identified between posterior interosseous neuropathy and lateral epicondyle soreness, and between median neuropathy and any neurological pattern, and trapezius and lateral epicondyle soreness. Conclusions Pain correlated with palpation soreness, which again correlated with the neurological patterns. Palpation soreness may be less significant as a marker of a painful disorder as it correlated no better with regional than with overall pain. The physical examination of computer operators should include a sufficient neurological assessment.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2021, 34, 5; 679-691
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neurological and neurophysiological examinations of workers exposed to arsenic levels exceeding hygiene standards
Autorzy:
Sińczuk-Walczak, Halina
Janasik, Beata M.
Trzcinka-Ochocka, Małgorzata
Stanisławska, Magdalena
Szymczak, Maria
Hałatek, Tadeusz
Walusiak-Skorupa, Jolanta
Powiązania:
https://bibliotekanauki.pl/articles/2179016.pdf
Data publikacji:
2014-12-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational exposure
arsenic speciation
nervous system
neuropathy
neurophysiological test
Opis:
Objectives: The assessment of the neurotoxic effect of arsenic (As) and its inorganic compounds is still the subject of interest due to a growing As application in a large array of technologies and the need to constantly verify the principles of prevention and technological parameters. The aim of this study was to determine the status of the nervous system (NS) in workers exposed to As at concentrations exceeding hygiene standards (Threshold Limit Values (TLV) – 10 μg/m³, Biological Exposure Index (BEI) – 35 μg/l) and to analyze the relationship between the NS functional state, species of As in urine and As levels in the workplace air. Material and Methods: The study group comprised 21 men (mean age: 47.43±7.59) employed in a copper smelting factory (mean duration of employment: 22.29±11.09). The control group comprised 16 men, matched by age and work shifts. Arsenic levels in the workplace air (As-A) ranged from 0.7 to 92.3 μg/m³; (M = 25.18±28.83). The concentration of total arsenic in urine (Astot-U) ranged from 17.35 to 434.68 μg/l (M = 86.82±86.6). Results: Syndrome of peripheral nervous system (PNS) was manifested by extremity fatigue (28.6%), extremity pain (33.3%) and paresthesia in the lower extremities (33.3%), as well as by neuropathy-type mini-symptoms (23.8%). Electroneurographic (ENeG) tests of peroneal nerves showed significantly decreased response amplitude with normal values of motor conduction velocity (MCV). Stimulation of sural nerves revealed a significantly slowed sensory conduction velocity (SCV) and decreased sensory potential amplitude. Neurophysiological parameters and the results of biological and environmental monitoring showed a relationship between $\text{As}^\text{tot}$, $\text{As}^\text{III}$ (trivalent arsenic), the sum of iAs ($\text{As}^\text{III}+\text{As}^\text{V}$ (pentavalent arsenic))+MMA (monomethylarsonic acid) concentration in urine and As levels in the air. Conclusions: The results of the study demonstrate that occupational exposure to inorganic arsenic levels exceeding hygiene standards (TLV, BEI) generates disorders typical of peripheral neuropathy.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2014, 27, 6; 1013-1025
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diabetic autonomic neuropathy of the gastrointestinal tract - etiopathogenesis, diagnosis, treatment and complications
Autorzy:
Kuzemko, Dorota
Rymarz, Ewa
Prystupa, Andrzej
Dzida, Grzegorz
Mosiewicz, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/972715.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
diabetic neuropathies
diabetes complications
diabetes mellitus
gastrointestinal autonomic neuropathy
Opis:
Introduction. Late complications of diabetes mellitus are a serious challenge for physicians treating diabetic patients. Micro- and macro-angiopathic changes are of the most severe sequels. However, it should be remembered that the effects of long-term diabetes are also associated with changes in the peripheral nervous system. One of the complications most troublesome for patients is diabetic autonomic neuropathy of the gastrointestinal (GI) tract. Objective. The review article presents the pathogenesis of diabetic neuropathy of the autonomous gastrointestinal tract, and advances in the diagnosis and treatment of this disease. The study used materials in the database which demonstrate current standards of conduct, based on the principles of EBM. Brief description of the state of knowledge. Diabetic neuropathy is one of the most common complications of diabetes mellitus. According to epidemiologists, it affects 10% to even 100% of patients with long-standing disease. Damage to the nervous fibres mainly results from hyperglycaemia, which leads to the typical symptoms of dysfunction of GI tract segments. The main additional examinations include abdominal ultrasound (US) and abdominal X-ray. In cases with oesophageal disorders accompanied by dysphagia, gastroscopy is found useful for excluding possible neoplastic lesions. The gold standard for evaluation of gastric emptying is radioisotopic scintigraphy, however it is available only in some specialistic departments. Other recommended methods include: manometry, EGG, insulin tests, NMR and expiratory tests. To date, the problem has been managed symptomatically; in special cases, surgical interventions have been required. Conclusions. At present, a wide array of treatment options is available, including new forms of drugs and less radical surgical procedures carried out in numerous centres worldwide.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 1; 6-9
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
High-frequency ultrasound in carpal tunnel syndrome: assessment of patient eligibility for surgical treatment
Ocena przydatności badania USG z zastosowaniem głowicy wysokiej częstotliwości w kwalifikacji do operacyjnego leczenia zespołu kanału nadgarstka
Autorzy:
Kapuścińska, Katarzyna
Urbanik, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1053128.pdf
Data publikacji:
2015
Wydawca:
Medical Communications
Tematy:
nerw pośrodkowy
neuropatia uciskowa
ultrasonografia
zespół kanału nadgarstka
entrapment neuropathy
Opis:
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy and a frequent cause of sick leaves because of work-related hand overload. That is why an early diagnosis and adequate treatment (conservative or surgical) are essential for optimal patient management. Aim: The aim of the study is to assess the usefulness of high-frequency ultrasound in CTS for the assessment of patient eligibility for surgical treatment. Material and methods: The study involved 62 patients (50 women and 12 men, aged 28–70, mean age 55.2) with scheduled surgeries of CTS on the basis of clinical symptoms, physical examination performed by a neurosurgeon and a positive result of EMG testing. The ultrasound examinations of the wrist were performed in all these patients. On the basis of the collected data, the author has performed multiple analyses to confirm the usefulness of ultrasound imaging in assessing patient eligibility for surgical treatment of CTS. Results: US examinations showed evidence of median nerve compression at the level of the carpal tunnel in all of the examined patients. This was further confirmed during surgical procedures. The mean value of the cross-sectional area at the proximal part of the pisiform bone was 17.45 mm2 (min. 12 mm2, max. 31 mm2). Nerve hypoechogenicity proximal to the nerve compression site was visible in all 62 patients (100%). Increased nerve vascularity on the transverse section was present in 50 patients (80.65%). Conclusions: Ultrasonography with the use of high-frequency transducers is a valuable diagnostic tool both for assessing patient eligibility for surgical treatment of CTS, and in postoperative assessment of the treatment efficacy.
Zespół kanału nadgarstka (ZKN) jest najczęstszą neuropatią uciskową i częstą przyczyną zwolnień lekarskich z powodu przeciążenia ręki związanego z pracą. Optymalne postępowanie w tym zespole zależy od wczesnego rozpoznania i podjęcia odpowiedniego leczenia (zachowawczego lub operacyjnego). Cel pracy: Celem pracy jest określenie przydatności badania USG z zastosowaniem głowicy wysokiej częstotliwości w kwalifikowaniu do operacyjnego leczenia ZKN. Materiał i metoda: Materiał pracy stanowi grupa 62 pacjentów (50 kobiet i 12 mężczyzn w wieku od 28 do 70 lat; średnia wieku 55,2 roku) zakwalifikowanych do operacyjnego leczenia ZKN na podstawie objawów klinicznych i badania fizykalnego przeprowadzonego przez neurochirurga oraz pozytywnego wyniku badania EMG. Wykonano badanie USG u wszystkich tych chorych. Na podstawie uzyskanych danych przeprowadzono liczne analizy, mające na celu potwierdzenie przydatności badania USG w kwalifikowaniu do leczenia operacyjnego ZKN. Wyniki: U wszystkich osób z grupy badanej uwidoczniono w badaniu USG ucisk nerwu pośrodkowego na poziomie kanału nadgarstka, który potwierdzono podczas zabiegu operacyjnego. Średnia wartość pola przekroju nerwu pośrodkowego na poziomie bliższej części grochowatej wynosiła 17,45 mm2 (min. 12 mm2, max. 31 mm2). Obniżenie echogeniczności nerwu pośrodkowego powyżej miejsca ucisku stwierdzono u wszystkich 62 pacjentów (100%). Cechy wzmożonego unaczynienia nerwu na przekroju poprzecznym występowały u 50 osób (80,65%). Wnioski: Badanie USG z zastosowaniem głowicy wysokiej częstotliwości jest wartościową metodą diagnostyki obrazowej w kwalifikowaniu do operacyjnego leczenia zespołu kanału nadgarstka.
Źródło:
Journal of Ultrasonography; 2015, 15, 62; 283-291
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Heteroplasmy analysis in the Polish patients with 11778A mutation responsible for Leber hereditary optic neuropathy.
Autorzy:
Mroczek-Tońska, Katarzyna
Ratajska, Dorota
Guillot, Cecile
Sąsiek, Maria
Ambroziak, Anna
Lubos, Leszek
Bartnik, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1043837.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
11778A mutation
mitochondrial DNA
human
Leber hereditary optic neuropathy
Opis:
We have analysed the heteroplasmy level in 11 individuals from 3 families harbouring the mitochondrial 11778A mutation responsible for Leber hereditary optic neuropathy using last cycle hot PCR. The mutation level exceeded 90% both in affected and in unaffected individuals. We also checked whether any of the families belonged to the J haplogroup of mitochondrial DNA and obtained a negative result.
Źródło:
Acta Biochimica Polonica; 2002, 49, 1; 257-262
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prevalence of carpal tunnel syndrome and its correlation with pain amongst female hairdressers
Autorzy:
Demiryurek, Bekir Enes
Aksoy Gündoğdu, Aslı
Powiązania:
https://bibliotekanauki.pl/articles/2159914.pdf
Data publikacji:
2017-12-21
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
pain
carpal tunnel syndrome
hairdressers
female workers
Boston questionnaire
neuropathy
Opis:
Objectives Carpal tunnel syndrome (CTS) may develop with repetitive and forced movements of the hands and wrists. In this study, we have aimed to evaluate whether the frequency of CTS is increased amongst female hairdressers as compared with unemployed women or not. Besides, we have also analyzed whether the functionality and pain intensity levels amongst female hairdressers with CTS are different from the ones of unemployed women with CTS or not. Material and Methods The consecutive female hairdressers and unemployed women who had referred to our electroneuromyography (ENMG) laboratory for the upper extremity nerve conduction studies were included. They were evaluated in terms of clinical and ENMG findings, socio-demographic characteristics, functionality and pain intensity levels determined with the Boston CTS Questionnaire and visual analog scale (VAS). Results In this study, 110 women (70 female hairdressers and 40 unemployed women) were included. The frequency of CTS among hairdressers (74.3%) was higher than the one of the unemployed control group (55%) (p = 0.032). We detected that as the time period of occupation in hairdressing increased, the risk of developing CTS also increased among hairdressers (p < 0.001). Additionally, pain intensity and functional loss levels were higher for hairdressers with CTS than those for the control group with CTS (p = 0.005, p < 0.001, p = 0.028, respectively). Conclusions The frequency of CTS is elevated for female hairdressers with respect to the unemployed women as in many other occupations requiring forced or repetitive hand movements. Besides, the occupational exposure in hairdressing also results in more elevated pain intensity and functional loss levels related with CTS as compared with the unemployed subjects. Int J Occup Med Environ Health 2018;31(3):333–339
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2018, 31, 3; 333-339
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bilateral hypermobility of ulnar nerves at the elbow joint with unilateral left ulnar neuropathy in a computer user: A case study
Autorzy:
Lewańska, Magdalena
Grzegorzewski, Andrzej
Walusiak-Skorupa, Jolanta
Powiązania:
https://bibliotekanauki.pl/articles/2177050.pdf
Data publikacji:
2015-11-24
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
ulnar nerve
ulnar nerve compression
ulnar neuropathies
hypermobility
neuropathy
computer
Opis:
Occupational ulnar neuropathy at the elbow joint develops in the course of long term direct pressure on the nerve and a persistently flexed elbow posture, but first of all, it is strongly associated with “holding a tool in a certain position” repetitively. Therefore, computer work only in exceptional cases can be considered as a risk factor for the neuropathy. Ulnar hypermobility at the elbow might be one of the risk factors in the development of occupational ulnar neuropathy; however, this issue still remains disputable. As this condition is mostly of congenital origin, an additional factor, such as a direct acute or chronic professional or non-professional trauma, is needed for clinical manifestations. We describe a patient – a computer user with a right ulnar nerve complete dislocation and left ulnar nerve hypermobility, unaware of her anomaly until symptoms of left ulnar neuropathy occurred in the course of job exposure. The patient was exposed to repetitive long lasting pressure of the left elbow and forearm on the hard support on the cupboard and desk because of a non-ergonomically designed workplace. The additional coexistent congenital abnormal displacement of the ulnar nerve from the postcondylar groove during flexion at the elbow increased the possibility of its mechanical injury. We recognized left ulnar neuropathy at the ulnar groove as an occupational disease. An early and accurate diagnosis of any form of hypermobility of ulnar nerve, informing patients about it, prevention of an ulnar nerve injury as well as compliance with ergonomic rules are essential to avoid development of occupational and non-occupational neuropathy.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2016, 29, 3; 517-522
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 28

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies