Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "acanthamoeba" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-15 z 38
Tytuł:
Secondary amoebic eye infections in mice due to Acanthamoeba sp.
Autorzy:
Mazur, T.
Hadas, E.
Gustowska, L.
Winiecka-Krusnell, J.
Linder, E.
Powiązania:
https://bibliotekanauki.pl/articles/838373.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Acanthamoeba
Acanthamoeba keratitis
mouse
infection
mice
eye
amoeba
Acanthamoeba castellanii
Acanthamoeba polyphaga
central nervous system
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Taste and Smell in Acanthamoeba Feeding
Autorzy:
KHAN, Naveed Ahmed
IQBAL, Junaid
SIDDIQUI, Ruqaiyyah
Powiązania:
https://bibliotekanauki.pl/articles/763505.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Acanthamoeba, chemoreception, protist, model organism
Opis:
The ability to detect food in the environment is an essential function among all living organisms and must have arisen at the beginning of life. The anatomical, morphological and molecular features involved in taste and smell may differ among disparate groups, but the principle of chemoreception is conserved. Here we debate the sense of taste and smell in the feeding behaviour of the unicellular protist, Acanthamoeba.
Źródło:
Acta Protozoologica; 2014, 53, 2
1689-0027
Pojawia się w:
Acta Protozoologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Extracerebral infections of Acanthamoeba spp.in mice. Pathomorphological changes in tissues of infected animals
Autorzy:
Mazur, T.
Gustowska, L.
Hadas, E.
Powiązania:
https://bibliotekanauki.pl/articles/839327.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parasite
Acanthamoeba
Acanthamoeba keratitis
mouse
extracerebral infection
mice
pathomorphological change
Acanthamoeba pneumonitis
granulomatous amoebic encephalitis
infected animal
central nervous system
tissue
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Response of Acanthamoeba castellanii mitochondria to oxidative stress
Autorzy:
Trocha, Lidia
Stobienia, Olgierd
Powiązania:
https://bibliotekanauki.pl/articles/1040871.pdf
Data publikacji:
2007
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Acanthamoeba castellanii
hydroperoxide
mitochondria
oxidative stress
Opis:
The purpose of this study was to examine the effects of oxidative stress caused by hydroperoxide (H2O2) in the presence of iron ions (Fe2+) on mitochondria of the amoeba Acanthamoeba castellanii. We used isolated mitochondria of A. castellanii and exposed them to four levels of H2O2 concentration: 0.5, 5, 15, and 25 mM. We measured basic energetics of mitochondria: oxygen consumption in phosphorylation state (state 3) and resting state (state 4), respiratory coefficient rates (RC), ADP/O ratios, membrane potential (ΔΨm), ability to accumulate Ca2+ , and cytochrome c release. Our results show that the increasing concentrations of H2O2 stimulates respiration in states 3 and 4. The highest concentration of H2O2 caused a 3-fold increase in respiration in state 3 compared to the control. Respiratory coefficients and ADP/O ratios decreased with increasing stress conditions. Membrane potential significantly collapsed with increasing hydroperoxide concentration. The ability to accumulate Ca2+ also decreased with the increasing stress treatment. The lowest stress treatment (0.5 mM H2O2) significantly decreased oxygen consumption in state 3 and 4, RC, and membrane potential. The ADP/O ratio decreased significantly under 5 mM H2O2 treatment, while Ca2+ accumulation rate decreased significantly at 15 mM H2O2. We also observed cytochrome c release under increasing stress conditions. However, this release was not linear. These results indicate that as low as 0.5 mM H2O2 with Fe2+ damage the basic energetics of mitochondria of the unicellular eukaryotic organism Acanthamoeba castellanii.
Źródło:
Acta Biochimica Polonica; 2007, 54, 4; 797-803
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of in vitro effect of selected contact lens solutions conjugated with nanoparticles in terms of preventive approach to public health risk generated by Acanthamoeba strains
Autorzy:
Padzik, M.
Hendiger, E.B.
Żochowska, A.
Szczepaniak, J.
Baltaza, W.
Pietruczuk-Padzik, A.
Olędzka, G.
Chomicz, L.
Powiązania:
https://bibliotekanauki.pl/articles/2082951.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
Acanthamoeba keratitis
contact lens solutions
silver/gold nanoparticles
Acanthamoeba trophozoites
anti-amoebic in
vitro effect
Opis:
Introduction. Various Acanthamoeba species are free-living organisms widely distributed in the human environment. Amphizoic amoebae as facultative parasites may cause vision-threatening eye disease – Acanthamoeba keratitis, mostly among contact lens wearers. As the number of cases is increasing, and applied therapy often unsuccessful, proper hygienic measures and effective contact lenses disinfection are crucial for the prevention of this disease. Available contact lens solutions are not fully effective against amphizoic amoebae; there is a need to enhance their disinfecting activity to prevent amoebic infections. The use of developing nanotechnology methods already applied with success in the prevention, diagnostic and therapy of other infectious diseases might be helpful regarding amoebic keratitis. This study assesses the in vitro effect of selected contact lens solutions conjugated with nanoparticles against Acanthamoeba trophozoites. Materials and method. Three selected contact lens solutions conjugated with silver and gold nanoparticles in concentration of 0.25–2.5 ppm were used in vitro against the axenically cultured ATCC 30010 type Acanthamoeba castellanii strain. The anti-amoebic efficacy was examined based on the oxido-reduction of AlamarBlue. The cytotoxicity tests based on the measurement of lactate dehydrogenase (LDH) activity were performed using a fibroblast HS-5 cell line. Results. Enhancement of the anti-amoebic activity of contact lens solutions conjugated with selected nanoparticles expressed in the dose dependent amoebic growth inhibition with a low cytotoxicity profile was observed. Conclusions. Results of the study showed that conjugation of selected contact lens solutions with silver nanoparticles might be a promising approach to prevent Acanthamoeba keratitis among contact lens users.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 198-202
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pełzaki wolno żyjące jako zagrożenie dla zdrowia ludzkiego
Free-living amoebae as threat of human health
Autorzy:
Jascaniene, N.
Leonska-Duniec, A.
Powiązania:
https://bibliotekanauki.pl/articles/789961.pdf
Data publikacji:
2012
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
ameby
Protista
Acanthamoeba
chorobotworczosc
zagrozenia zdrowia
Źródło:
Zeszyty Naukowe. Prace Instytutu Kultury Fizycznej. Uniwersytet Szczeciński; 2012, 28
1640-6818
Pojawia się w:
Zeszyty Naukowe. Prace Instytutu Kultury Fizycznej. Uniwersytet Szczeciński
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Basic energetic parameters of Acanthamoeba castellanii mitochondria and their resistance to oxidative stress
Autorzy:
Jarmuszkiewicz, Wieslawa
Antos-Krzeminska, Nina
Drachal-Chrul, Danuta
Matkovic, Karolina
Nobik, Wioletta
Pieńkowska, Joanna
Swida, Aleksandra
Woyda-Ploszczyca, Andrzej
Budzinska, Malgorzata
Powiązania:
https://bibliotekanauki.pl/articles/1040753.pdf
Data publikacji:
2008
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Acanthamoeba castellanii
mitochondria
hydrogen peroxide
oxidative stress
Opis:
The purpose of this study was establishing the basic energetic parameters of amoeba Acanthamoeba castellanii mitochondria respiring with malate and their response to oxidative stress caused by hydrogen peroxide in the presence of Fe2+ ions. It appeared that, contrary to a previous report (Trocha LK, Stobienia O (2007) Acta Biochim Polon 54: 797), H2O2-treated mitochondria of A. castellanii did not display any substantial impairment. No marked changes in cytochrome pathway activity were found, as in the presence of an inhibitor of alternative oxidase no effects were observed on the rates of uncoupled and phosphorylating respiration and on coupling parameters. Only in the absence of the alternative oxidase inhibitor, non-phosphorylating respiration progressively decreased with increasing concentration of H2O2, while the coupling parameters (respiratory control ratio and ADP/O ratio) slightly improved, which may indicate some inactivation of the alternative oxidase. Moreover, our results show no change in membrane potential, Ca2+ uptake and accumulation ability, mitochondrial outer membrane integrity and cytochrome c release for 0.5-25 mM H2O2-treated versus control (H2O2-untreated) mitochondria. These results indicate that short (5 min) incubation of A. castellanii mitochondria with H2O2 in the presence of Fe2+ does not damage their basic energetics.
Źródło:
Acta Biochimica Polonica; 2008, 55, 2; 349-356
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The contribution of uncoupling protein and ATP synthase to state 3 respiration in Acanthamoeba castellanii mitochondria.
Autorzy:
Jarmuszkiewicz, Wiesława
Czarna, Małgorzata
Sluse-Goffart, Claudine
Sluse, Francis
Powiązania:
https://bibliotekanauki.pl/articles/1043287.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Acanthamoeba castellanii
uncoupling protein
energy-dissipating
mitochondria
Opis:
Mitochondria of the amoeba Acanthamoeba castellanii possess a free fatty acid-activated uncoupling protein (AcUCP) that mediates proton re-uptake driven by the mitochondrial proton electrochemical gradient. We show that AcUCP activity diverts energy from ATP synthesis during state 3 mitochondrial respiration in a fatty acid-dependent way. The efficiency of AcUCP in mitochondrial uncoupling increases when the state 3 respiratory rate decreases as the AcUCP contribution is constant at a given linoleic acid concentration while the ATP synthase contribution decreases with respiratory rate. Respiration sustained by this energy-dissipating process remains constant at a given linoleic acid concentration until more than 60% inhibition of state 3 respiration by n-butyl malonate is achieved. The present study supports the validity of the ADP/O method to determine the actual contributions of AcUCP (activated with various linoleic acid concentrations) and ATP synthase in state 3 respiration of A. castellanii mitochondria fully depleted of free fatty acid-activated and describes how the two contributions vary when the rate of succinate dehydrogenase is decreased by succinate uptake limitation.
Źródło:
Acta Biochimica Polonica; 2004, 51, 2; 533-538
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Human infections caused by free-living amoebae
Autorzy:
Król-Turmińska, Katarzyna
Olender, Alina
Powiązania:
https://bibliotekanauki.pl/articles/989767.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
acanthamoeba
naegleriafowleri
balamuthia mandrillaris
amebiasis
protozoal infections
Opis:
Introduction. Among free-living amoebae that are widely distributed in nature only four genera/species are known as agents of human infections: Acanthamoeba spp., Naegleriafowleri, Balamuthia mandrillaris and Sappiniapedata. These amoebae are not well adapted to parasitism, and could exist in the human environment without the need for a host. Infections due to these amoebae, despite low morbidity, are characterized by relatively high mortality rate and pose serious clinical problems. Objectve. This review study presents and summarizes current knowledge about infections due to pathogenic and opportunistic free-living amoebae focused on epidemiology, clinical manifestations, diagnosis and treatment based on global literature. State of knowledge. All four genera have been recognized as etiologic factors of fatal central nervous system infections and other serious diseases in humans. N. fowleri causes an acute fulminating meningoencephalitis in children and young adults. Acanthamoeba spp. and B.mandrillaris are opportunistic pathogens causing granulomatous amoebic encephalitis and disseminated or localized infections which could affect the skin, sinuses, lungs, adrenals and/or bones. Acanthamoeba spp. is also the main agent of acute eye infection – Acanthamoeba keratitis, mostly in contact lens wearers. However, there is only one recognized case of encephalitis caused by S. pedata. Conclusions. Amoebic diseases are difficult to diagnose which leads to delayed treatment, and result in a high mortality rate. Considering those issues, there is an urgent need to draw more attention to this type of diseases.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
First Report of a Case of Prostatitis Due to Acanthamoeba in a Dog
Autorzy:
Lorenzo-Morales, Jacob
Valladares, María
Sancho, Jaione
Reyes-Batllé, María
Martín-Navarro, Carmen M.
López-Arencibia, Atteneri
González, Ana C.
López-Medina, Luis
Piñero, José E.
Martínez-Carretero, Enrique
Valladares, Basilio
Powiązania:
https://bibliotekanauki.pl/articles/763401.pdf
Data publikacji:
2013
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Dog, prostate, Acanthamoeba, PCR, genotype T4
Opis:
The first case of prostatitis in a ten year old mixed breed dog due to Acanthamoeba genotype T4 is reported. The dog was suffering from kidney dysfunction and was admitted for exploration of its organs by echography. All organs were in normal conditions with the exception of the prostate which showed signs of inflammation. An ultrasound-guided puncture was thus performed for further cytological and microbiological study. When the obtained fluid was observed under the microscope, Acanthamoeba trophozoites were detected in a high number. No other pathogens were isolated. Both culture and PCR were positive for Acanthamoeba genus and the isolate was later identified as genotype T4. Unfortunately at this stage, the dog’s owner decided to reject any kind of treatment or therapy. To the best of our knowledge, this is the first report of prostatitis in a dog due to Acanthamoeba genus.
Źródło:
Acta Protozoologica; 2013, 52, 4
1689-0027
Pojawia się w:
Acta Protozoologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acanthamoeba in the Domestic Water Supply of Huntington, West Virginia, U.S.A.
Autorzy:
Trzyna, Wendy
Mbugua, Margaret W.
Rogerson, Andrew
Powiązania:
https://bibliotekanauki.pl/articles/763579.pdf
Data publikacji:
2010
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Amoebic Keratitis, amoebae, tap water, Acanthamoeba, chlorine tolerance
Opis:
The aim of this study was to determine the prevalence of Acanthamoeba in the domestic water supply in Huntington, West Virginia (U.S.A.) and the factors that may contribute to their presence or absence. One hundred sixty-two one liter tap water samples were collected over eight months. Amoebae in the samples (cysts or trophozoites) were harvested by passively filtering onto 5 μm pore size filters and enriching for amoebae on non-nutrient amoeba saline agar plates seeded with Escherichia coli for cultivation. Thirteen percent of all samples were positive for amoebae and 9.3% were positive for the amoeba of interest, Acanthamoeba. Chlorine levels were determined for samples at the time of collection, yielding a mean level of 1.56 mg l–1 chlorine in the distribution system ca. 8 kilometers from the water treatment plant. Cysts and trophozoites of Acanthamoeba clonal isolates were found to tolerate up to 50 mg l–1 and 4 mg l–1 chlorine respectively. This study showed that Acanthamoeba were present in the domestic water supply in Huntington, WV and although no attempt was made to count cells in liter samples, their frequency of occurrence (9.3%) and failure to be present in all replicates, suggests they were present at background levels of perhaps a few cells per five liters. This is only the second U.S. study to consider amoebae in tap water and is unique since the source water was river water. Acanthamoeba trophozoites and cysts were able to withstand levels of chlorine higher than those typically found in tap water suggesting they may be present in either form in the distribution system. Acanthamoeba are opportunistic pathogens capable of causing eye infections and their presence in tap water is a potential risk factor for susceptible individuals, particularly contact lens wearers who may use tap water to clean lenses and storage cases.
Źródło:
Acta Protozoologica; 2010, 49, 1
1689-0027
Pojawia się w:
Acta Protozoologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
More Acanthamoeba Genotypes: Limits to Use rDNA Fragments to Describe New Genotype
Autorzy:
Corsaro, Daniele
Powiązania:
https://bibliotekanauki.pl/articles/763668.pdf
Data publikacji:
2011
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
Acanthamoeba, genotype, full gene sequence, partial gene sequence
Opis:
Strains of the genus Acanthamoeba are usually assigned to sequence types or genotypes according to pair-wise similarity values of the nuclear gene for the small subunit of ribosomal RNA. This classification system was established by comparing full or nearly full gene sequences, > 2000 bp. For practical reasons, diagnostic fragments of smaller lengths have been identified and used for rapid and economic identification of large number of strains. While the use of these small fragments in diagnostics applications remains valid when and only if the reference full sequence-type is available, we contest their use to identify and describe new genotypes. We report herein the case of a new genotype described on the basis of solely a small partial sequence and discuss the poor reliability of this fragment to correctly infer phylogenetic relationships, and its limits in the description of new genotypes of Acanthamoeba.
Źródło:
Acta Protozoologica; 2011, 50, 1
1689-0027
Pojawia się w:
Acta Protozoologica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of growth at low temperature on the alternative pathway respiration in Acanthamoeba castellanii mitochondria.
Autorzy:
Jarmuszkiewicz, Wiesława
Frączyk, Olaf
Hryniewiecka, Lilla
Powiązania:
https://bibliotekanauki.pl/articles/1044102.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Acanthamoeba castellanii
low temperature adaptation
alternative oxidase
mitochondria
Opis:
Mitochondria of amoeba Acanthamoeba castellanii in addition to the conventional cytochrome pathway possess, like plant mitochondria, a cyanide-resistant alternative quinol oxidase. In mitochondria isolated from amoeba batch culture grown temporarily at low temperature (6°C), higher respiration was accompanied by lower coupling parameters as compared to control culture (grown at 28°C). In the presence of benzohydroxamate, respiratory rates and coupling parameters were similar in both types of mitochondria indicating that growth in cold conditions did not disturb the cytochrome pathway. Increased contribution of alternative oxidase in total mitochondrial respiration in low-temperature-grown amoeba cells was confirmed by calculation of its contribution using ADP/O measurements. Furthermore, in mitochondria from low-temperature- grown cells the content of the alternative oxidase was increased and correlated with the increase in the unstimulated and GMP-stimulated cyanide-resistant respiratory activity. A possible physiological role of higher activity of alternative oxidase as response to growth at a low temperature in unicellular organisms, such as amoeba, is discussed.
Źródło:
Acta Biochimica Polonica; 2001, 48, 3; 729-737
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Amoebicidal or amoebostatic influence of disinfectants used in health facilities and laboratories on corneal strains of Acanthamoeba
Autorzy:
Baltaza, Wanda
Padzik, Marcin
Szaflik, Jacek P.
Dybicz, Monika
Hendiger, Edyta
Chomicz, Lidia
Powiązania:
https://bibliotekanauki.pl/articles/972267.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
in vitro dynamics
influence of disinfectants
Acanthamoeba strains
Opis:
Different Acanthamoeba species are amphizoic organisms distributed in wide range of habitats in natural and man-made environments; they are also detected on surfaces of equipment and accessories in health facilities. Some strains of the amoebae are causative agents of the vision-threatening human disease Acanthamoeba keratitis, mainly reported in contact lens wearers. An exceptional high resistance of Acanthamoeba trophozoites and particularly cysts to chemicals, disinfectants and drugs is believed as influencing difficulty resulting in unsuccessful therapeutic management. As Acanthamoeba keratitis is the serious medical problem worldwide, different chemicals with possible activity against environmental and clinical Acanthamoeba strains are tested. In our study, selected disinfectants used in health care settings and laboratories were tested and their efficacy against the corneal strains Acanthamoeba castellanii and A. polyphaga , and environmental A. castellanii Neff strain was assessed. Comparative assessment of results of the assays show that, apart from amoebistatic effects, the disinfectants indicated expected cysticidal efficacy.
Źródło:
Annals of Parasitology; 2017, 63, 3; 162-172
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Contact lens-related combined Pseudomonas aeruginosa, Acanthamoeba and Candida keratitis among adolescents girls
Autorzy:
Świerczyńska, Marta
Tronina, Agnieszka
Bogocz, Michał
Mrukwa-Kominek, Ewa
Filipek, Erita
Powiązania:
https://bibliotekanauki.pl/articles/2046699.pdf
Data publikacji:
2022-03-31
Wydawca:
Medical Education
Tematy:
infectious keratitis
contact lenses
Candida
Acanthamoeba
Pseudomonas aeruginosa
Opis:
Background: We present a case of combined Pseudomonas aeruginosa, Acanthamoeba and Candida keratitis and clinical course of treatment in two adolescents girls who did not follow the rules of proper use of soft contact lenses. Case reports: Two teenage contact lens users sought medical attention, reporting visual impairment, redness and pain of the eye. Slit lamp examination showed unilateral corneal ulcer. Confocal microscopy revealed images compatible with amoebic cysts and yeasts cells, whereas the results of conjunctival swabs confirmed the presence of Pseudomonas aeruginosa. After topical and general treatment in the first patient, the corneal defect was healed, and visual acuity improved. The girl remains under the constant supervision of an ophthalmological clinic. The medications were gradually reduced, but with time she developed crystalline keratopathy. Regrettably, the second patient, despite the applied treatment had recurrent inflammation and progressive corneal thinning, which required amniotic membrane transplantation to prevent perforation. Conclusion: The early identification of the pathogen as well as adequate treatment is crucial, as contact lens-associated keratitis are potentially sight threatening. Patient and caregiver education, adequate contact lens hygiene and consistent follow-up are important to prevent serious complications.
Źródło:
OphthaTherapy; 2022, 9, 1; 36-44
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 38

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies