Temat: transgenic animal - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Primordial germ cells ( PGCs) as a tool for creating transgenic chickens
Autorzy:: Chojnacka-Puchta, L.
Kasperczyk, K.
Plucienniczak, G.
Sawicka, D.
Bednarczyk, M.
Powiązania:: https://bibliotekanauki.pl/articles/32300.pdf
Data publikacji:: 2012
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: primordial germ cell
transgenic animal
chicken
transgene expression
bioreactor
ovalbumin
Opis:: The transgenic chicken has great potential as a bioreactor for the production of valuable pharmaceutical proteins, notably in the oviduct/egg. Whereas conventional transgenic approaches have significant limitations in this species, an alternative approach employing primordial germ cells (PGCs), the progenitor cells to ova and spermatozoa, has now been successfully applied to the insertion of exogenous genes into birds. Recent developments in manipulating avian embryos make it possible to produce germline chimeras derived from transferred PGCs. In this review we describe the migration pathway of chicken PGCs during early development. We then summarize different methods for the isolation of PGCs and the diversity of techniques used to introduce genes into these cells. Finally, we describe an in vitro assay for testing tissue-specific vectors designed to express heterologous proteins in transgenic chickens.
Źródło:: Polish Journal of Veterinary Sciences; 2012, 15, 1
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Animal cloning by nuclear transfer: state-of-the-art and future perspectives
Autorzy:: Dinnyes, Andras
Szmolenszky, Agnes
Powiązania:: https://bibliotekanauki.pl/articles/1041360.pdf
Data publikacji:: 2005
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: transgenic
animal models
epigenetics
cloning
Opis:: Model organisms are essential to study the genetic basis of human diseases. Transgenic mammalian models, especially genetic knock-out mice have catalysed the progress in this area. To continue the advancement, further sophisticated and refined models are crucially needed to study the genetic basis and manifestations of numerous human diseases. Coinciding with the start of the new era of post-genomic research, new tools for establishment of transgenesis, such as nuclear transfer and gene targeting in somatic cells, have become available, offering a unique opportunity for the generation of transgenic animal models. The new technology provides important tools for comparative functional genomics to promote the interpretation and increase the practical value of the data generated in numerous mouse models. This paper discusses the state-of-the-art of the nuclear replacement technology and presents future perspectives.
Źródło:: Acta Biochimica Polonica; 2005, 52, 3; 585-588
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Unconventional uses of pigs
Niekonwencjonalne użytkowanie świń
Autorzy:: Klocek, C.
Nowicki, J.
Magiera, A.
Penar, W.
Powiązania:: https://bibliotekanauki.pl/articles/2082437.pdf
Data publikacji:: 2019
Wydawca:: Szkoła Główna Gospodarstwa Wiejskiego w Warszawie. Wydawnictwo Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie
Tematy:: pigs
senses
animal welfare
medical
tests
transgenic pigs
Opis:: Unconventional uses of pigs. The study presents the possibilities of pigs’ sensory organs and their sensitivity to odor stimuli (i.e. to search for truffles and drugs by pigs), as well as their role in the animal adaptation processes. We use the knowledge about the senses to more effectively enrich farming environment and in this way to improve the animal welfare. The pigs’ ability to distinguish and remember sounds and the appropriate associated reaction can be used to create the desired behavior, improve welfare of pigs and their production results. Similarly, the pigs’ ability to distinguish colors and their color preferences also enable to influence the behavior, welfare, and production effects of pigs. Miniature pigs are used as companion animals and in rehabilitation. The similarity in the anatomical structure of the pig and human organs, and the course of physiological and metabolic processes are used in medical research and creates hope for their use in so-called xenotransplantation. Transgenic pigs create new horizons in the unconventional use of pigs.
Źródło:: Annals of Warsaw University of Life Sciences - SGGW. Animal Science; 2019, 58[4]; 251-260
1898-8830
Pojawia się w:: Annals of Warsaw University of Life Sciences - SGGW. Animal Science
Dostawca treści:: Biblioteka Nauki

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