Temat: retinoblastoma - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Constitutional chromosome instability in families with patients affected by sporadic non-hereditary retinoblastoma
Autorzy:: Zajaczek, S
Gorski, B.
Krzystolik, Z.
Lubinski, J.
Powiązania:: https://bibliotekanauki.pl/articles/2043598.pdf
Data publikacji:: 1999
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: retinoblastoma
sporadic non-hereditary retinoblastoma
chromosome
patient
bleomycin test
Źródło:: Journal of Applied Genetics; 1999, 40, 4; 343-353
1234-1983
Pojawia się w:: Journal of Applied Genetics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Molecular analysis of a large novel constitutional deletion in a patient with sporadic unilateral retinoblastoma
Autorzy:: Zajaczek, S
Cragg, H.
Jakubowska, A.
Gorski, B.
Krzystolik, Z.
Cowell, J.K.
Lubinski, J.
Powiązania:: https://bibliotekanauki.pl/articles/2043635.pdf
Data publikacji:: 1999
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: retinoblastoma
large deletion
patient
Rb-1 gene
constitutional mutation
peripheral blood lymphocyte
molecular analysis
sporadic unilateral retinoblastoma
DNA
cancer
Źródło:: Journal of Applied Genetics; 1999, 40, 3; 233-239
1234-1983
Pojawia się w:: Journal of Applied Genetics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: The first Rb-1 gene promoter germ-line de novo mutation in patient with retinoblastoma
Autorzy:: Zajaczek, S
Jakubowska, A.
Kurzawski, G.
Krzystolik, Z.
Lubinski, J.
Powiązania:: https://bibliotekanauki.pl/articles/2043638.pdf
Data publikacji:: 1999
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: retinoblastoma
genetics
patient
Rb-1 gene
de novo mutation
Źródło:: Journal of Applied Genetics; 1999, 40, 3; 241-247
1234-1983
Pojawia się w:: Journal of Applied Genetics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Radiation stability of 125I-brachytherapy sources
Autorzy:: Saxena, S.
Ram, R.
Dash, A.
Joshi, P.
Venkatesh, M.
Powiązania:: https://bibliotekanauki.pl/articles/148254.pdf
Data publikacji:: 2007
Wydawca:: Instytut Chemii i Techniki Jądrowej
Tematy:: retinoblastoma
125 I-brachytherapy sources
radiation stability
SEM
leach rate
Opis:: Low energy 125I-brachytherapy sources are used for the treatment of retinoblastoma and many other forms of eye cancer. Such sources were prepared by adsorption of 125I on palladium coated silver rods and were critically evaluated for safety aspects, as per AERB standards. In order to attain low leachability and to facilitate leak free laser encapsulation of sources within titanium capsules of size 0.8 mm (f) ´ 4.75 mm (l), the radioactive source core was coated with polystyrene. With a view to study the radiation stability of such sources over a period of three weeks, both polymer coated radioactive sources and inactive source cores were separately subjected to an integrated gamma dose of ~(17.85 ´ 104) Gy (17.85 MRad), which is the dose expected to be received in three weeks from a source containing ~ 111 MBq of 125I. This was carried out to test their suitability for reuse within such period. SEM pictures of inactive source cores were taken to observe the effect of gamma radiation on palladium coating. Post-irradiation leachability and uniformity of activity of radioactive sources were evaluated and found to be satisfactory. The sources were found to be reusable safely, for repeated brachytherapy procedures over a practically useful time of at least three weeks.
Źródło:: Nukleonika; 2007, 52, 1; 13-16
0029-5922
1508-5791
Pojawia się w:: Nukleonika
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Squamous cell oesophageal cancer in retinoblastoma survivor: does germinal RB1 mutation influence chemo- and radiosensitivity?
Autorzy:: Dworzecki, Tomasz
Smolska-Ciszewska, Beata
Suwiński, Rafał
Powiązania:: https://bibliotekanauki.pl/articles/1065813.pdf
Data publikacji:: 2014
Wydawca:: Medical Education
Tematy:: case report
chemoresistance
radiosensitivity
retinoblastoma
second malignancy
squamous cell esophageal cancer
Opis:: The case of complete response of squamous cell oesophageal cancer to radiochemotherapy in patient previously operated due to hereditary retinoblastoma is presented. Second cancers in retinoblastoma survivors are the main cause of death in that group of patients in developed countries. There is little data on the outcome of treatment in those patients but the few papers available suggest rather poor prognosis. However, it is not clear whether the biology of cancer determined by RB gene mutation is responsible for that. The data suggesting decreased radio- and chemoresistance in cancers with decreased RB gene expression is discussed in the present paper. The role of that gene in the response to cancer treatment was showed in lung, breast and bladder cancer. Moreover, laboratory studies seem to confirm clinical observations and show that RB gene inhibition leads to increased cytotoxic effect of cisplatin, etoposide and 5-fluorouracil. It seems that without the incorporation of gene expression profiling into clinical practice further improvement in cancer treatment will be difficult to achieve.
Źródło:: OncoReview; 2014, 4, 2; A72-75
2450-6125
Pojawia się w:: OncoReview
Dostawca treści:: Biblioteka Nauki

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