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Wyszukujesz frazę "mucormycosis" wg kryterium: Temat


Wyświetlanie 1-6 z 6
Tytuł:
Nasal Mucormycosis: Our experience with 24 cases
Autorzy:
Bakshi, Satvinder Singh
Das, Soumyajit
Ramesh, Seepana
Gopalakrishnan, Suriyanarayanan
Powiązania:
https://bibliotekanauki.pl/articles/1397391.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
amphotericin B
debridement
invasive fungal infection
mucormycosis
mycoses
rhinocerebral mucormycosis
zygomycosis
Opis:
Background: Mucormycosis is a rare fungal infection affecting people with impaired immunity. The aim of this study is to shed light on the epidemiology, incidence, and outcome of patients with mucormycosis hospitalized at a tertiary care center in Pondicherry. Methods: We conducted a retrospective chart review between January 2008 and January 2018. All patients with proven or probable mucormycosis were included. Results: A total of 24 patients were included. Their median age was 49 years and the majority were males. Comorbidities included mainly hematologic malignancy and diabetes mellitus. A liposomal amphotericin B formulation alone or in combination with other antifungals was used as a first line agent in all patients. Conclusion: The incidence of mucormycosis has significantly increased over the past 10 years at our institution, most likely due to increased risk factors.
Źródło:
Polish Journal of Otolaryngology; 2020, 74, 4; 37-40
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Compositional profiling and molecular docking studies of Eucalyptus polybrachtea essential oil against mucormycosis and aspergillosis
Autorzy:
Sharma, Arun Dev
Kaur, Inderjeet
Chauhan, Amrita
Powiązania:
https://bibliotekanauki.pl/articles/16710066.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
aspergillosis
mucormycosis
eucalyptus oil
herbal drug
Opis:
Essential oil (EO) from Eucalyptus polybrachtea is used as complementary and traditional medicine worldwide. The present study aimed at compositional profiling of EO and molecular docking of EO’s bioactive compound 1,8 cineole against fungal enzymes involved in the riboflavin synthesis pathway, namely riboflavin synthase (RS), riboflavin biosynthesis protein RibD domain-containing protein (RibD), and 3,4-dihydroxy-2-butanone 4-phosphate synthase (DBPS) as apposite sites for drug designing against aspergillosis and mucormycosis, and in vitro confirmation. The compositional profile of EO was completed by GC-FID analysis. For molecular docking, the Patchdock tool was used. The ligand-enzyme 3-D interactions were examined, and ADMET properties (absorption, distribution, metabolism, excretion, and toxicity) were calculated. GC-FID discovered the occurrence of 1,8 cineole as a major component in EO, which was subsequently used for docking analysis. The docking analysis revealed that 1,8 cineole actively bound to RS, RibD, and DBPS fungal enzymes. The results of the docking studies demonstrated that the ligand 1,8 cineole exhibited H-bond and hydrophobic interactions with RS, RibD, and DBPS fungal enzymes. 1,8 cineole obeyed Lpinsky’s rule and exhibited adequate bioactivity. Wet-lab authentication was achieved by using three fungal strains: Aspergillus niger, Aspergillus oryzae, and Mucor sp. Wet lab results indicated that EO was able to inhibit fungal growth.
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2023, 104, 3; 233-245
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Death due to rare rhinocerebral mucormycosis infection: a case report
Autorzy:
Baral, T.
Mugada, V.
Kolakota, R.K.
Powiązania:
https://bibliotekanauki.pl/articles/2088062.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
Mucormycosis
Diabetes mellitus
Orbital cellulitis
amphotericin B
Opis:
Background: Rhinocerebral mucormycosis is the most common form of mucormycosis in patients with diabetes mellitus; it is linked to poor prognosis, presenting most commonly in an acute setting, mimicking symptoms of sinusitis or periorbital cellulitis. The general survival rate in chronic cases is 83%, compared to 10–35% in acute. Aim of the study: To report a death due to rhinocerebral mucormycosis in a 45-year-old male patient. Case report: In this case report a 45-year-old male presented with acute rhinocerebral mucormycosis and was admitted in a state of unconsciousness with complaints of sudden onset weakness of right upper and lower limb, motor aphasia, right facial swelling, orbital swelling, and diminished distant vision. Upon primary diagnosis of stroke, treatment started immediately. However, past medical history from patient’s attendants revealed that the patient underwent a tooth extraction procedure 20 days prior, and had since developed redness of the right eye, diminished distant vision, and swelling of the right side of the face. Pus was drained, and reports revealed orbital cellulitis with an intracranial spread. By the time of admission to hospital, the patient had abnormal lab profiles (WBC, ESR, serum creatinine), acute kidney injury, with MRI revealing rhinocerebral mucormycosis. The patient developed septic shock and died during treatment. Conclusions: Acute mucormycosis carries a high mortality rate. Pleiotropic manifestations and organ dysfunction add to the further risk of mortality. Timely diagnosis and management may increase the chances of the survival rate of the patient.
Źródło:
Medical Science Pulse; 2019, 13, 4; 40-43
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Abdominal wall fungal co-infection mucormycosis associated with COVID-19: a case report.
Autorzy:
Saseedharan, Sanjith
Patil, Shalaka
Kadam, Vaijaynti
Mehendale, Vinay
Powiązania:
https://bibliotekanauki.pl/articles/1918238.pdf
Data publikacji:
2021-12-31
Wydawca:
Towarzystwo Pomocy Doraźnej
Tematy:
Case report
Covid-19
mucormycosis
pregnancy
Fungal Infection
Opis:
The Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has posed a public health system challenge across the globe. A retrospective analysis of COVID-19 globally surmises that the fungal co-infections associated with COVID-19 might be missed or misdiagnosed. However, data regarding all the signs and symptoms of COVID-19 are insufficient. The available few publications conclude that patients with COVID-19 have a higher susceptibility to fungal coinfections. Mucormycosis is a rare and often lifethreatening fungal disease characterized by vascular invasion by hyphae, resulting in thrombosis and necrosis. Based on the available data it seems COVID-19 patients, especially severely ill or immunocompromised, have a higher susceptibility to invasive mycoses. Therefore, it is important to assess the risk factors, the types of invasive mycosis, the strengths and limitations of diagnostic methods, clinical settings, and the need for standard or individualized treatment in COVID-19 patients. A 33 years old female operated case of laparoscopic ectopic removal with salpingectomy and tubectomy, at post-operative Day 5 had redness and pus discharge from the operative site and was diagnosed with abdominal wall cellulitis. She underwent local exploration and wound wash. At post operative day 5, the patient came to our emergency room with mild disorientation, cellulitis, and pain at the port insertion site. On examination, we highlight BP 90/50 mmg and blood test analysis with HB-8.3, leucocyte count 29.91×109/L, CRP 333mg/L. CT scan revealed necrotizing fasciitis. She then underwent wide local excision and debridement. Post debridement the next day during dressing, the wound showed a cotton fluffy appearance at the edges and part of the base with black necrotic areas. Wound swab was sent for fungal culture, KOH mount, blood culture, pus culture, and tissue for histopathology. In the meantime, she was started on empirical antifungal amphotericin B, meropenem and minocycline antibiotics. Covid antibodies test was done which were reactive: 1.96. Tissue histopathology revealed mucormycosis. A high degree of suspicion and promptness in starting antifungal prevented fatal outcome.
Źródło:
Critical Care Innovations; 2021, 4, 4; 45-52
2545-2533
Pojawia się w:
Critical Care Innovations
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mucormycosis in a patient with acute myeloblastic leukemia following liver transplantation for Wilson’s disease
Autorzy:
Łanocha, A.A.
Guzicka-Kazimierczak, R.
Zdziarska, B.
Wawrzynowicz-Syczewska, M.
Powiązania:
https://bibliotekanauki.pl/articles/2085182.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
Mucormycosis
acute myeloblastic leukemia
Willson’s disease
liver transplantation
Opis:
A case is presented of mucormycosis in a patient with acute myeloblastic leukemia following liver transplantation for Wilson’s disease. A 58-year-old female was admitted to the Department of Haematology with deterioration of her general condition, loss of appetite, tiredness and difficulty with mental contact for a few days. Blood and urine cultures for bacteria and fungus, galactomannan antigen were negative. Whole body computed tomography demonstrated bilateral hilar lymphadenopathy with necrotic lesions: splenomegaly with a hypodensive lesion 13 × 20 × 19 mm and lower pulmonary infiltrates suggested fungal etiology. Magnetic resonance imaging of the brain showed thickened meninges. Finally, mucormycosis was diagnosed. Treatment with amphotericin B lipid complex was started, resulting in an partial improvement of the general condition and decreased level of inflammatory markers. However, the patient’s condition continued to deteriorate, with sepsis etiology Escherichia coli, and despite the intensive managements she eventually died.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 665-668
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Covid-19 and mucormycosis (Black Fungus): An epidemic within the pandemic
Autorzy:
Gambhir, R.S.
Aggarwal, A.
Bhardwaj, A.
Kaur, A.
Sohi, R.K.
Mehta, S.
Powiązania:
https://bibliotekanauki.pl/articles/2085943.pdf
Data publikacji:
2021
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
COVID-19
SARS-CoV-2 pandemic
mucormycosis
India
diabetes
Black fungus
Opis:
The second wave of the COVID-19 pandemic has affected India significantly with country reporting more than 400,000 cases in the month of May 2021 and health system almost collapsing. This was attributed to the new mutant strain also called as the ‘Delta Strain’ which led to high surge of cases across the country. As the country was stabilising over this situation, another imminent threat in the form of Covid Associated Mucormycosis (CAM) challenged the already burdened health system of India. Also called as ‘Black Fungus,’ cases of CAM began to rise rapidly in the last week of May 2021 with multiple states reporting steady rise in the number of cases. Based on the published literature, India contributed to approximately 71% of global cases of CAM from December 2019 to start of April 2021, with majority of the cases occurring during the second wave. The present paper focuses on the epidemic of CAM during the second wave in India highlighting the causes, symptoms and various treatment modalities that have been adopted to cure the disease. Also, spotlight has also been thrown on some other nations where cases of CAM have begun to emerge. Some key recommendations are also mentioned which can prove vital towards disease prevention.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2021, 72, 3; 239-244
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-6 z 6

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