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Tytuł:
The influence of the sterilization process on the microscopic structure of hyaluronic acid-based nanofibrous scaffolds
Autorzy:
Boguń, M.
Kadłubowski, S.
Pabjańczyk-Wlazło, E.
Szparaga, G.
Chrzanowski, M.
Krucińska, I.
Powiązania:
https://bibliotekanauki.pl/articles/285940.pdf
Data publikacji:
2016
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
hyaluronic acid
scaffolds
sterilization
Źródło:
Engineering of Biomaterials; 2016, 19, 138; 65
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Artificial skin composites
Autorzy:
Ładniak, Agata
Powiązania:
https://bibliotekanauki.pl/articles/2079951.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Tematy:
titanium dioxide,
chitosan
hyaluronic acid
skin substitutes
Opis:
Skin injuries are a health problem and can lead to serious, significant deterioration in the quality of life and, consequently, even illness and disability. Therefore, after wounding, immediate regeneration of the tissue is necessary to avoid further complications and pathogenesis. Consequently, many wound healing strategies have been developed, leading to the progress in constructing of multifunctional tissue substitutes for the skin, biomembranes, scaffolds and intelligent dressings. The field of science focusing on the creation of the above-mentioned products is tissue engineering (TE). Its main goal is to find a system that is able to replace or be a model that perfectly mimics the form and function of the skin. Research carried out on such constructs is mainly based on the analysis of mechanical properties (porosity, elasticity), as well as the assessment of the impact of individual components on processes related to the formation of new tissue as cell proliferation and differentiation, proliferation, angiogenesis - through in vivo studies (using animal models: mice, New Zealand rabbits) and in vitro (most often using mouse fibroblasts - L929). Skin constructions may have potential applications as wound dressings or skin substitutes in cases of severe skin damage.
Źródło:
Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia; 2018, 73, 1; 51-60
2083-358X
Pojawia się w:
Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The separation of microscale HA in aqueous solution by foam separation technique
Autorzy:
Wenyao, Shao
Xiao, Gong
Shuming, Cui
Ying, Lin
Yinghua, Lu
Yuqing, Chen
Powiązania:
https://bibliotekanauki.pl/articles/949357.pdf
Data publikacji:
2019
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:
Foam Separation
Hyaluronic Acid
Enrichment Ratio
Recovery Rate
Opis:
Hyaluronic acid (HA) has important applications in fields of health care products, cosmetics and clinical medical. However, the unique physiological properties of HA make cost of its traditional separation and extraction process relatively high. Foam separation technique has simple, gentle and efficient advantages on the separation of substances with surface activity by using bubbles as the separation medium. In this paper, natural surfactant CocamideBetaine (CAPB) was used as a foaming agent to explore the technology of microscale HA in aqueous solution by foam separation. The optimum process conditions were determined based on the recovery rate and enrichment ratio of HA by single factor and orthogonal experiment: at room temperature, pH = 7, separating air velocity (v) = 350 mL/min, HA concentration (CHA) = 50 mg/L, adding liquid volume (V) = 200 mL, collecting time (tcol) = 10 min, CAPB concentration (CCAPB) = 0.035 g/L. Under these conditions, HA enrichment ratio (E) equals 6.821 and HA recovery rate (R) equals 66.425%.
Źródło:
Polish Journal of Chemical Technology; 2019, 21, 4; 66-71
1509-8117
1899-4741
Pojawia się w:
Polish Journal of Chemical Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characterisation of chitosan/hyaluronic acid blend films modified by collagen
Autorzy:
Lewandowska, Katarzyna
Sionkowska, Alina
Grabska, Sylwia
Michalska, Marta
Powiązania:
https://bibliotekanauki.pl/articles/1034575.pdf
Data publikacji:
2017
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
chitosan
collagen
hyaluronic acid
polymer blends
surface properties
Opis:
In the present study, thin films based on the blends of chitosan (Ch) and hyaluronic acid (HA) with and without collagen (Coll) were characterised using tensile tests, attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and thermogravimetric analysis (TGA). Ch/HA and Ch/HA/Coll polymer blends were prepared using the solvent evaporation technique. The interactions between polymer components in the binary and ternary blends were studied by FTIR analysis. Mechanical properties were studied and compared with those of simple polymer films. These results show that the addition of collagen into Ch/HA blends led to the increase of tensile strength and Young modulus. Moreover, it was found that the thermal stability of the Ch/HA binary blend significantly increased upon the addition of collagen.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2017, 22; 125-134
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The influence of the type solvent on the structure of chitosan blends with hyaluronic acid
Autorzy:
Lewandowska, Katarzyna
Sionkowska, Alina
Grabska, Sylwia
Powiązania:
https://bibliotekanauki.pl/articles/1034698.pdf
Data publikacji:
2016
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
chitosan
hyaluronic acid
microscopy.
polymer blends
surface properties
Opis:
The influence of the type solvent on the structure of chitosan, hyaluronic acid and their blend films was investigated. Aqueous acetic acid, hydrochloric acid, sodium chloride and aqueous acetic acid/NaCl were used as solvents for chitosan, hyaluronic acid and Ch/HA solution blends. Ch, HA and their blend films were prepared by casting technique. The homogeneity and morphology of chitosan blends were ascertained from the tapping-mode atomic force microscopy (AFM) and scanning electron microscopy (SEM). The changes of topography images are considered by determining the root mean square (RMS, Rq) deviation in the image data. The surface roughness of chitosan, hyaluronic acid and Ch/HA blended films was altered by mixing. The structure of chitosan blends with hyaluronic acid depends on the blend composition and on the solvent used for preparing the blend.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2016, 21; 147-153
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of chitosan, hyaluronic acid and/or titanium dioxide on the physicochemical characteristic of phospholipid film/glass surface
Autorzy:
Ładniak, Agata
Jurak, Małgorzata
Wiącek, Agnieszka Ewa
Powiązania:
https://bibliotekanauki.pl/articles/109601.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
chitosan
titanium dioxide
hyaluronic acid
phospholipid
adhesion
topography
Opis:
The production of preparations, whose destination action takes place in close proximity to living cells, increases the necessity to carry out studies concerning the determination of the biomaterial surface effect on the cellular response. In achieving this goal, physicochemical characteristic of the surface can be helpful. This can be established based on topography, chemical composition, wettability, and surface energy analysis. In addition, determining the changes of these properties which can occur as a result of surface modification will allow prediction of cell behaviour when contacting with biomaterial. In the study, the Langmuir-Blodgett technique was used. It enabled the transfer of the Langmuir monolayer formed from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) to a solid support. The DPPC film imitated a natural biological membrane capable of interacting with the components of the liquid subphase: chitosan (Ch), hyaluronic acid (HA) and/or titanium dioxide (TiO2). Depending on the type and strength of interactions of phospholipid molecules with the components of the subphase, the films obtained on the solid support were characterized by specific surface properties. Their characteristics based mainly on values of the work of adhesion in connection with films topography, allowed for statement that it is possible to form semi-interpenetrating Ch network in which HA is entrapped, contributing to the enhanced adhesion of the DPPC film, additionally intensified by TiO2 inclusion. This type of research permit for better understanding of the interactions at the interface, cell membrane-Ch/HA/TiO2 and can be important in the creation of a new generation of skin or tissue substitutes.
Źródło:
Physicochemical Problems of Mineral Processing; 2019, 55, 6; 1535-1548
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cytokeratin-18 and hyaluronic acid levels predict liver fibrosis in children with non-alcoholic fatty liver disease
Autorzy:
Lebensztejn, Dariusz
Wierzbicka, Aldona
Socha, Piotr
Pronicki, Maciej
Skiba, Elżbieta
Werpachowska, Irena
Kaczmarski, Maciej
Powiązania:
https://bibliotekanauki.pl/articles/1039852.pdf
Data publikacji:
2011
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
NAFLD
laminin
cytokeratin-18
hyaluronic acid
YKL-40
children
Opis:
Objectives: There is a need to replace liver biopsy with non-invasive markers that predict the degree of liver fibrosis in fatty liver disease related to obesity. Therefore, we studied four potential serum markers of liver fibrosis and compared them with histopathological findings in liver biopsy in children with non-alcoholic fatty liver disease (NAFLD). Methods: We determined fasting serum level of hyaluronic acid (HA), laminin, YKL-40 and cytokeratin-18 M30 in 52 children (age range 4-19, mean 12 years, 80 % of them were overweight or obese) with biopsy-verified NAFLD. Viral hepatitis, autoimmune and metabolic liver diseases (Wilson's disease, alpha-1-antitrypsin deficiency, cystic fibrosis) were excluded. Fibrosis stage was assessed in a blinded fashion by one pathologist according to Kleiner. Receiver operating characteristics (ROC) analysis was used to calculate the power of the assays to detect liver fibrosis (AccuROC, Canada). Results: Liver fibrosis was diagnosed in 19 children (37 %). The levels of HA and CK18M30 were significantly higher in children with fibrosis compared to children without fibrosis (p=0.04 and 0.05 respectively). The ability of serum HA (cut-off 19.1 ng/ml, Se=84 %, Sp=55 %, PPV=52 %, NPV=86 %) and CK18M30 (cut-off 210 u/l, Se=79 %, Sp=60 %, PPV=56 %, NPV=82 %) to differentiate children with fibrosis from those without fibrosis was significant (AUC=0.672 and 0.666, respectively). The combination of both markers was superior (AUC=0.73, p=0.002). Laminin and YKL-40 levels did not allow a useful prediction. Conclusions: Cytokeratin-18 and hyaluronic acid are suitable serum markers predicting liver fibrosis in children with NAFLD. Studying these markers may identify patients at risk of disease progression.
Źródło:
Acta Biochimica Polonica; 2011, 58, 4; 563-566
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Podłoża włókniste z pochodnej kwasu hialuronowego otrzymane metodą elektroprzędzenia
Hyaluronic acid-derived fibrous materials prepared by electrospinning
Autorzy:
Król, P.
Pabjańczyk-Wlazło, E.
Chrznowski, M.
Krucińska, I.
Szparaga, G.
Boguń, M.
Powiązania:
https://bibliotekanauki.pl/articles/285200.pdf
Data publikacji:
2014
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
biomateriały
nanowłókna
kwas hialuronowy
biomaterials
fibrous materials
hyaluronic acid
Opis:
Celem realizowanej pracy badawczej jest dobranie układu: polimer – rozpuszczalnik – substancja pomocnicza, aby uzyskać metodą elektroprzędzenia biozgodne włókniste podłoża z kwasu hialuronowego o nano- i mikro- metrycznych rozmiarach włókien. W przeprowadzonych badaniach skupiono się nad doborem stężenia roztworu oraz rodzajem i ilością substancji pomocniczych. W dalszej części badań objętych projektem 2012/07/B/ST8/03378 zrealizowane zostaną badania nad wpływem rodzaju i ilości wprowadzonych aktywnych dodatków: antybiotyków z rodziny cefalosporyn oraz cynku. Określony zostanie także wpływ typowych rozpuszczalników, a także obecność środków powierzchniowo czynnych na odpowiedź komórkową i cytotoksyczność takich struktur.
The objective of the project will be to select the polymer/solvent/additive system to prepare fibres and fibrous matrices enriched with active substances from the hyaluronic acid matrix by electrospinning with nano- and micro- metric sizes of fibers. The aim of this study was to select a concentration and composition of spinning solutions as well as the type and amount auxiliary substances. In the next part of the research, included in the project 2012/07/B/ST8/03378, the studies on the influence of the type and amount entered active additives: cephalosporin family of antibiotics and zinc will be implemented. Simultaneously, the effect of typical solvents used in electrospinning and the presence of surfactants in polymer solutions on cellular cytotoxicity response of such structures will be defined.
Źródło:
Engineering of Biomaterials; 2014, 17, no. 128-129; 26-28
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A tubular polycaprolactone/hyaluronic acid scaffolds for nasal cartilage tissue engineering
Autorzy:
Jatteau, S.
Kurowska, A.
Ziąbka, M.
Rajzer, I.
Powiązania:
https://bibliotekanauki.pl/articles/285184.pdf
Data publikacji:
2017
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
electrospinning
tissue engineering scaffolds
nasal cartilages
hyaluronic acid
PCL
Opis:
In this preliminary study, 3D nanofibrous porous scaffolds in the form of spiral tubes for future application as nasal cartilages implants were fabricated by combining polycaprolactone electrospun fibers with drug modified hyaluronic acid gel. It is expected that the spiral form of the scaffold with open geometries, large surface area, and distance between the scaffold walls will be helpful for improving future cell penetration into the scaffolds, nutrient transport and metabolic waste removal, which are otherwise limited in conventional electrospun tissue-engineered scaffolds. The tubular scaffolds structure, its porosity and fibers’ diameter were assessed via scanning electron microscopy, and biological properties of the scaffolds were evaluated in an in vitro study using Simulated Body Fluid (SBF). SEM results showed that apatite formed within a short period on tubular scaffolds after its immersion in SBF, demonstrating high in vitro bioactivity of the scaffolds.
Źródło:
Engineering of Biomaterials; 2017, 20, 141; 8-12
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Development of an Electrospun Nanofibrous Web with Hyaluronic Acid
Wytwarzanie elektroprzędzionego runa z udziałem kwasu hialuronowego
Autorzy:
Milašius, R.
Ryklin, D.
Yasinskaya, N.
Yeutushenka, A.
Ragaišiene, A.
Rukuižiene, Ž.
Mikučioniene, D.
Powiązania:
https://bibliotekanauki.pl/articles/233968.pdf
Data publikacji:
2017
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
electrospinning
nanofibres
hyaluronic acid
polyamide
elektroprzędzenie
runo
kwas hialuronowy
poliamid
Opis:
Textile materials with an electrospun nanofibrous web can be used fo ar wide range of applications, including medicine and health care. In this research, polyamide-6 and hyaluronic acid were used for the development of a nanofibrous web via electrospinning. Hyaluronic acid is one of the most interesting ingredients used in skin care. It is very important that the electrospun polyamide-6 nanofibrous structure binds nanoparticles of hyaluronic acid not covering the surface of these particles. The main goal of this work was to develop an electrospun nanofibrous polyamide-6 web with hyaluronic acid which can be used for health care and/or cosmetology A. polyamide-6 nanofibrous web with hyaluronic acid was successfully developed via electrospinning. The presence of hyaluronic acid in the nanoweb was confirmed after web treatment with hot (95%) water. Hyaluronic acid was transported from the spinning solution to the electrospun web, was not isolated from the environment by polyamide-6, and could interact with human skin.
Materiały tekstylne z elektroprzędzionym runem znajdują szeroki zakres zastosowań w produkcji materiałów do zastosowań medycznych. W pracy wytworzono za pomocą elektroprzędzenia runo z poliamidu 6 i kwasu hialuronowego. Kwas hialuronowy jest jednym z najbardziej obiecujących składników stosowanych w pielęgnacji skóry. Istotne jest, aby struktura nanowłókna poliamidowego wiązała nanocząsteczki kwasu hialuronowego, nie pokrywając powierzchni tych cząstek. Głównym celem pracy było opracowanie runa poliamidowego z kwasem hialuronowym, które może być zastosowane w wyrobach medycznych i/lub kosmetologii.
Źródło:
Fibres & Textiles in Eastern Europe; 2017, 5 (125); 8-12
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-10 z 42

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