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    Wyświetlanie 1-5 z 5
    Tytuł:
    Immunomodulacyjne właściwości mikroorganizmów
    Autorzy:
    Ograczyk, E.
    Micota, B.
    Miszczyk, E.
    Gajewski, E.
    Włodarczyk, M.
    Rudnicka, K.
    Sadowska, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/273631.pdf
    Data publikacji:
    2015
    Wydawca:
    Roble
    Tematy:
    immunomodulacja
    mikrobiota
    odporność immunologiczna
    Helicobacter pylori
    Mycobacterium tuberculosis
    Staphylococcus aureus
    immunomodulation
    microbiota
    immunological resistance
    Źródło:
    LAB Laboratoria, Aparatura, Badania; 2015, 20, 3; 11-18
    1427-5619
    Pojawia się w:
    LAB Laboratoria, Aparatura, Badania
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of Modified Interference Wedge Method in Measurements of Indices of Refraction and Birefringence of Nematic Liquid Crystals
    Autorzy:
    Kowiorski, K.
    Kędzierski, J.
    Raszewski, Z.
    Kojdecki, M.
    Herman, J.
    Miszczyk, E.
    Piecek, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/1399015.pdf
    Data publikacji:
    2013-12
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    78.15.+e
    Opis:
    Wedge cell filled with a homogeneously oriented nematic liquid crystal was exploited as an interference wedge to measuring indices of refraction. Interference fringes from the wedge were observed in polarised light in reflection or transmission mode of a polarisation microscope to determining ordinary and extraordinary indices of refraction or birefringence (i.e. anisotropy of both indices). The interference fringes close to wedge apex were uniform and could be well described in two-beam interference approximation. The refractive indices were computed with using simple formulae involving only distances between subsequent fringes in a cell filled with the liquid crystal and an empty reference cell. Several new highly-birefringent nematic mixtures produced in the Military University of Technology were investigated. The 6CHBT nematic was used as the reference material.
    Źródło:
    Acta Physica Polonica A; 2013, 124, 6; 946-948
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    In vitro assay of the biological activity of bisphosphonates
    Autorzy:
    Chmielewska, E.
    Miszczyk, P.
    Kafarski, P.
    Kempińska, K.
    Wietrzyk, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/1190037.pdf
    Data publikacji:
    2015
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    bisfosfoniany
    cytotoksyczność
    in vitro
    aktywność biologiczna
    inhibitor
    bisphosphonates
    cytotoxicity
    biological activity
    Opis:
    Nowadays, the use of bisphosphonates are the gold standard of treatment of bone diseases. Due to the high utility of these compounds, scientists still search for better and better structures, with a variety of substituents at carbon’s atom and create new libraries or improve methods of their synthesis. To determine the potential effect of newly discovered bisphosphonates, for example antiosteoporotic activity, there are in vitro tests which allow to determine the half maximal inhibitory concentrations (IC50) of cells. This paper describes in detail the methodology for test the biological activity of bisphosphonates. Shows the results of biological activity for synthesized bisphosphonates in relation to the commercial-incadronate and zoledronate.
    Źródło:
    Interdisciplinary Journal of Engineering Sciences; 2014, 2, 1; 13--16
    2300-5874
    Pojawia się w:
    Interdisciplinary Journal of Engineering Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Comparison of Methods in Studies of Cell Death Mechanisms
    Autorzy:
    Borkowska, A.
    Nowakowski, M.
    Miszczyk, J.
    Lipiec, E.
    Wiltowska-Zuber, J.
    Rawojć, K.
    Kwiatek, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/1030322.pdf
    Data publikacji:
    2018-02
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    growth and division
    cell processes
    fluorescence
    optimization
    Opis:
    While studying the influence of ionizing radiation or certain chemical agents on cells, it is crucial to not only determine cytotoxicity, but also to follow cell death mechanisms. There are different methods to screen processes of cell death and still very important question remains unanswered about differences in results that could be caused by various experimental steps in procedures. Based on literature review two protocols of cell death determination were compared. First protocol regarded collecting cells floating in medium before trypsinization and following centrifugation of them. In the second protocol floating cells were discarded and attached ones were stained and fixed. In all experiments three different untreated cell lines (A172, DU145 as cancer cell lines and in comparison, fibroblasts (FB CCL 110), as a non- cancerous cell line) were used to test applied protocols. Cells were cultured and death processes were examined at different time points up to 120 h. Compared protocols showed statistically significant differences, especially in terms of necrosis, which was higher when included floating cells from culture medium and then centrifuging them. Therefore, presented results show importance of choosing a valid experimental procedure in case of evaluating cells viability and types of cell death pathways quantitatively.
    Źródło:
    Acta Physica Polonica A; 2018, 133, 2; 263-266
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Increased prevalence of overweight and obesity among Polish children age 14-18 between 2001 and 2013 from Krakow, Poland - a cross-sectional study
    Autorzy:
    Dyląg, K.A.
    Klimek-Piotrowska, W.
    Koziej, M.
    Hołda, M.K.
    Piątek, K.
    Wszołek, K.
    Tyszka, A.
    Kmiotek, E.
    Pliczko, M.
    Śliwińska, A.
    Krauss, K.
    Miszczyk, M.
    Waligóra, M
    Powiązania:
    https://bibliotekanauki.pl/articles/1916715.pdf
    Data publikacji:
    2015
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    pediatric obesity
    health measurements
    Adiposity
    Opis:
    Introduction: So far, very little data on pediatric obesity has been published in Poland, although the problem seems to be growing.Objective: To investigate present prevalence of overweight and obesity among schoolchildren using CDC (Center of Disease Control and Prevention) criteria in Krakow and to compare how it has changed between the years 2001 and 2013. Our aim was to establish the magnitude of this rising problem within the last decade.Materials and methods: The study was conducted in two phases. In 2001, height and weight of the group of schoolchildren were obtained. Twelve years later, children in the same age, attending the same schools, were measured and weighed. Using the collected data, BMI (kg/m2) was calculated in order to acquire BMI percentile. BMI cutoffs referential for Polish population were used.Results: Using the CDC criteria to diagnose children as obese or overweight, the authors determined that the prevalence of overweight, including obesity was 10.8% in 2001 and changed to 15.1% in 2013 (p=0.0054). The percentage of obese children increased from 2.0% to 4.8% (p=0.0012). The occurrence of overweight and obesity has increased among girls (p=0.0025; p=0.0112 respectively) while among the group of boys, it did not change. The factors associated with excess weight were: male sex (OR=1.48; 95%CI=1.13-1.95) and second phase of the study (OR= 1.48; 95%CI=1.13-1.95).Conclusion: Our study indicated that the prevalence of obesity and overweight among adolescents in Krakow rose within the last decade. The rising problem affected females more than males. Despite that, excess weight is still more frequent among males than females.
    Źródło:
    Progress in Health Sciences; 2015, 5, 1; 156-161
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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