Autor: Jarosław, Skokowski, - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Biobankowanie ludzkiego materiału biologicznego dla celów naukowych w Polsce i w Europie
Autorzy:: Łukasz, Kozera,
Dominik, Strapagiel,
Joanna, Gleńska-Olender,
Anna, Chrościcka,
Katarzyna, Ferdyn,
Jarosław, Skokowski,
Leszek, Kalinowski,
Jakub, Pawlikowski,
Błażej, Marciniak,
Markus, Pasterk,
Agnieszka, Matera-Witkiewicz,
Małgorzata, Lewandowska-Szumieł,
Michał, Piast,
Małgorzata, Witoń,
Powiązania:: https://bibliotekanauki.pl/articles/902739.pdf
Data publikacji:: 2018-06-22
Wydawca:: Uniwersytet Warszawski. Wydawnictwa Uniwersytetu Warszawskiego
Tematy:: Consortium of Polish Biobanks
BBMRI
data protection
Konsorcjum Polskich Biobanków
rejestr biobanków
ochrona danych
Opis:: Biobanks are one of the 10 Ideas Changing the World Right now – according to Time Magazine (2009). Samples and data deposition have become an increasing. trend in the world. Europe has invested a lot of money into infrastructures responsible for collection and storage of human biological samples. Poland, a country with a population of over 38.5 million people has just started investing funds into this powerful and indispensable tool for scientific research. Consortium of Polish Biobanks named as BBMRI.pl consisting of seven well-established biobanks developed a project for the Creation of the Polish Biobanking Network in order to organise our infrastructures according to world-recognized standards. The main tasks include: creation of Consortium of Polish Biobanks, development of IT solutions coherent with pan European needs, development of quality assurance tools, establishment of the Biobanking National Node, development of quality control programme and analysis of Ethical, Legal and Social Implications of research using human samples. Results of this project will increase Poland’s position in the international research arena of biomedicine, make our biorepositories open for international collaboration and in the future will contribute to the development of personalized medicine.
Źródło:: Studia Iuridica; 2018, 73; 13-28
0137-4346
Pojawia się w:: Studia Iuridica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Abnormal FHIT gene transcript and c-myc and c-erbB2 amplification in breast cancer.
Autorzy:: Kowara, Renata
Gołębiowski, Filip
Chrzan, Paweł
Skokowski, Jaroslaw
Karmolinski, Andrzej
Pawełczyk, Tadeusz
Powiązania:: https://bibliotekanauki.pl/articles/1043760.pdf
Data publikacji:: 2002
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: amplification
c-myc
FHIT transcripts
breast cancer
c-erbB2
Opis:: Searching for ways to improve the characterization of breast cancer we examined the relationship between the status of the FHIT gene transcript and amplification of c-myc and the c-erbB2 oncogene. Abnormal FHIT transcript was detected in 32 of 79 cancers examined. The presence of Fhit protein estimated by Western blots was evident only in cancers exhibiting a normal-sized FHIT transcript. This indicates that abnormal FHIT transcripts observed in our study did not encode any Fhit protein or the amount of such protein was very low. There was no association between the presence of aberrant FHIT gene transcript with age, tumor size, estrogen and progesterone receptor status, local metastases and histological grading. However, the abnormalities in FHIT gene transcripts were observed with different frequency depending on the histopathological type of the tumor. The aberrant FHIT transcript was detected in 60% of lobular cancers and only in 28% of ductal cancers. Analyzing the occurrence of c-myc and c-erbB2 amplification and the presence of aberrant FHIT gene transcripts we found that the aberrant FHIT transcript more frequently occurred in tissues with c-myc amplification. There was a significant (P <0.05) correlation between the occurrence of the aberrant FHIT gene transcript with accompanying c-myc amplification and positive lymph node status. However, in order to evaluate the predictive value of these findings in breast cancer, an extended clinical follow up will be necessary.
Źródło:: Acta Biochimica Polonica; 2002, 49, 2; 341-350
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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