Autor: Hartwich, A. - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Helicobacter pylori, gastrin and cyclooxygenases in gastric cancer
Autorzy:: Konturek, P.C.
Hartwich, A.
Zuchowicz, M.
Labza, H.
Pierzchalski, P.
Karczewska, E.
Bielanski, W.
Hahn, E.G.
Konturek, S.J.
Powiązania:: https://bibliotekanauki.pl/articles/69061.pdf
Data publikacji:: 2000
Wydawca:: Polskie Towarzystwo Fizjologiczne
Tematy:: hypergastrinemia
gastric cancer
infection
cyclooxygenase
apoptosis
stomach
gastrin
Helicobacter pylori
Źródło:: Journal of Physiology and Pharmacology; 2000, 51, 4,1
0867-5910
Pojawia się w:: Journal of Physiology and Pharmacology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Changes of albumin secondary structure after palmitic acid binding : FT-IR spectroscopic study
Autorzy:: Oleszko, A
Hartwich, J.
Gąsior-Głogowska, M.
Olsztyńska-Janus, S.
Powiązania:: https://bibliotekanauki.pl/articles/307332.pdf
Data publikacji:: 2018
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:: kwas palmitynowy
albumina
spektrometria FTIR
palmitic acid
albumin
Fourier transform infrared spectroscopy
protein secondary structure
Opis:: Purpose: Albumin is an universal transport protein. Plasma pool of free fatty acids arising from triglyceride hydrolysis, critical in energy metabolism and etiology of metabolic disorders is transported by albumin. According to various studies albumin has from seven to nine binding sites with diverse affinity to long chain fatty acids. X-ray diffraction crystallography measurements have provided data only for pure human serum albumin or albumin with fully saturated binding sites. These results have shown that amount of -helices is higher after fatty acids binding. Molecular mechanics simulations suggest that binding of fatty acids in two high-affinity sites leads to major conformational changes in albumin structure. The aim of this research was to investigate albumin secondary structure upon gradually increasing fatty acids to protein mole ratio. Methods: Fourier transform infrared spectroscopy was applied to study changes of bovine serum albumin (as an analogue of human serum albumin) -helical structures after binding palmitic acid in a range of 0–20 palmitic acid: albumin molar ratios representing pure protein, partial, full saturation and excess binding sites capacity. Results: Amount of -helices was increasing along with the amount of palmitic acid: bovine serum albumin molar ratio and reached maximum value around 2 mol/mol. Conclusions: Our studies confirmed molecular mechanics simulations and crystallographic studies. Palmitic acid binding in two high-affinity sites leads to major structural changes, filling another sites only slightly influenced bovine serum albumin secondary structure. The systematic study of fatty acids and albumin interactions, using an experimental model mimicking metabolic disorders, may results in new tools for personalized nanopharmacotherapy.
Źródło:: Acta of Bioengineering and Biomechanics; 2018, 20, 1; 59-64
1509-409X
2450-6303
Pojawia się w:: Acta of Bioengineering and Biomechanics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Fast Prototyping for Video Monitoring Systems with the Use of DSP Module
Autorzy:: Chmielewska, A.
Weychan, R.
Marciniak, T.
Dąbrowski, A.
Hartwich, M.
Owczarczak, M.
Powiązania:: https://bibliotekanauki.pl/articles/226392.pdf
Data publikacji:: 2013
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: video processing
CCTV system
urban surveillance monitoring
threat detection
Matlab / Simulink
Code Composer Studio
DSP
Opis:: This paper presents techniques for fast prototyping of real-time hardware / software video processing systems for urban surveillance monitoring equipment. During the experimental research the evaluation module with the TMS320DM6437 signal processor programmed with the use of the Code Composer Studio and Matlab / Simulink environments has been used. Analyzed algorithms can support the work of monitoring video operators. In particular, we analyzed efficiency of implementation of the algorithms using two examples: detection of painting theft and signaling of crossing a pedestrian pass at the red light.
Źródło:: International Journal of Electronics and Telecommunications; 2013, 59, 4; 375-381
2300-1933
Pojawia się w:: International Journal of Electronics and Telecommunications
Dostawca treści:: Biblioteka Nauki

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