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Wyszukujesz frazę "Hyaluronic Acid" wg kryterium: Wszystkie pola


Tytuł:
Hyaluronic acid suppresses age related skin changes
Autorzy:
Larkina, S. A.
Oleynik, N. N.
Vastyanov, R. S.
Powiązania:
https://bibliotekanauki.pl/articles/765461.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Mikołaja Kopernika w Toruniu. Wydział Nauk o Ziemi i Gospodarki Przestrzennej. Katedra Kultury Fizycznej
Tematy:
hyaluronic acid, skin, papillary layer, mesh layer, connective tissue, collagen, age-dependent changes
Opis:
Functioning of the skin with age leads to its changes under which the condition of the dermis fibers deteriorates, which affects the appearance of the person and causes a number of consecutive pathological processes in the skin deeper layers. The development of methods for the prevention and treatment of age-related involuntary changes in the skin, enhancement of repair processes in its various layers is relevant and has a scientific and practical significance. Morphological studies of rabbits skin after the exogenous hyaluronic acid (HA) administration in various concentrations were performed. Studies have shown that when HA various concentrations are injected intradermally into rabbits, the increase in the formation of connective tissue fibers in the dermis is manifested with an increase of HA concentration. An increase in the HA concentration in the compounds promotes an increase in the degree of compaction of the dermis of rabbits. Lower HA concentration (1.4% and 2%) after single administration causes stimulation of the processes inside the skin at earlier time (2 weeks), and a concentration of 4% - is more active at a later time (8 weeks). We can assume a connection between the HA concentration and the time of the manifestation of the most pronounced morphological changes in the skin. It is likely that the stimulating effect of HA is manifested when the optimal physiological concentration is reached. The obtained data are in favor of further studies of the influence of the concentration of exogenous HA on the processes of skin biorevitalization.
Źródło:
Journal of Education, Health and Sport; 2017, 7, 4
2391-8306
Pojawia się w:
Journal of Education, Health and Sport
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characterisation of chitosan/hyaluronic acid blend films modified by collagen
Autorzy:
Lewandowska, Katarzyna
Sionkowska, Alina
Grabska, Sylwia
Michalska, Marta
Powiązania:
https://bibliotekanauki.pl/articles/1034575.pdf
Data publikacji:
2017
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
chitosan
collagen
hyaluronic acid
polymer blends
surface properties
Opis:
In the present study, thin films based on the blends of chitosan (Ch) and hyaluronic acid (HA) with and without collagen (Coll) were characterised using tensile tests, attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and thermogravimetric analysis (TGA). Ch/HA and Ch/HA/Coll polymer blends were prepared using the solvent evaporation technique. The interactions between polymer components in the binary and ternary blends were studied by FTIR analysis. Mechanical properties were studied and compared with those of simple polymer films. These results show that the addition of collagen into Ch/HA blends led to the increase of tensile strength and Young modulus. Moreover, it was found that the thermal stability of the Ch/HA binary blend significantly increased upon the addition of collagen.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2017, 22; 125-134
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Enzymatyczna hydroliza kwasu hialuronowego
Enzymatic hydrolysis of hyaluronic acid
Autorzy:
Niesobska, A.
Trusek-Hołownia, A.
Powiązania:
https://bibliotekanauki.pl/articles/2073216.pdf
Data publikacji:
2015
Wydawca:
Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:
hialuronian
hialuronidaza
hydroliza enzymatyczna
immobilizacja substratu na membranie
hyaluronan
hyaluronidase
enzymatic hydrolysis
substrate immobilization on membrane
Opis:
W pracy badano i opisano wykorzystanie enzymu hydrolitycznego hialuronidazy do degradacji hialuronianu (HA) w postaci natywnej i immobilizowanej na membranie warstwy. Z przeprowadzonych eksperymentów wynika, że możliwa jest hydroliza HA prowadzona w pH dalekim od optymalnego dla działania enzymu. Uzyskane wartości stopnia hydrolizy wskazują na utrudnienia w dostępie enzymu do immobilizowanego substratu, co będzie przedmiotem dalszych badań.
Use of hyaluronidase hydrolytic enzyme for degradation of hyaluronan in a native form and immobilized as a layer on the flat membrane is described in the paper. The conducted experiments show that the HA hydrolysis occurs at pH far from optimal for the enzyme activity. The calculated degrees of hydrolysis indicate the hindered enzyme access to substrate. This issue will be a subject of further research.
Źródło:
Inżynieria i Aparatura Chemiczna; 2015, 4; 184--185
0368-0827
Pojawia się w:
Inżynieria i Aparatura Chemiczna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
New materials based on hyaluronic acid and egg albumin mixture
Autorzy:
Gadomska, Magdalena
Musiał, Katarzyna
Sionkowska, Alina
Powiązania:
https://bibliotekanauki.pl/articles/1844862.pdf
Data publikacji:
2021
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
hyaluronic acid
albumin from chicken egg
mechanical properties
polymer films
Opis:
In this work, new materials based on the mixture of hyaluronic acid and albumin from chicken eggs have been studied. Tests were carried out to determine the molecular weight of the tested hyaluronic acids. The properties of hyaluronic acid were investigated and significant differences were found in the mechanical properties of the tested compound, depending on its molecular weight. It was found that egg albumin can be combined with hyaluronic acid and thin films can be obtained. Spectrometric tests were performed both for pure compounds and for mixtures of hyaluronic acid with chicken egg albumin. IR spectroscopy showed that interactions between hyaluronic acid and egg albumin are mainly by hydrogen bonds, as the shifts in the main bands in IR spectra were observed. The addition of egg albumin to hyaluronic acid leads to the decrease of its mechanical properties. The deterioration of the mechanical properties of polymer films from HA-albumin mixtures may be due to interactions between compounds which were shown in the IR spectra. The thin films based on hyaluronic acid and egg albumin blend can be used as adhesive materials in biomedicine and cosmetics. Both biopolymers are biocompatible and biodegradable so we can expect a biocompatible and biodegradable material for potential application as adhesives.
Źródło:
Engineering of Biomaterials; 2021, 4, 160; 15-21
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The characterization of scaffolds based on dialdehyde chitosan/ hyaluronic acid
Autorzy:
Grabska-Zielińska, Sylwia
Sosik, Adrianna
Małkowska, Anna
Olewnik-Kruszkowska, Ewa
Stein-Brink, Kerstin
Kleszczyński, Konrad
Kaczmarek-Szczepańska, Beata
Powiązania:
https://bibliotekanauki.pl/articles/1844772.pdf
Data publikacji:
2021
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Źródło:
Engineering of Biomaterials; 2021, 24, 163; 76
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A tubular polycaprolactone/hyaluronic acid scaffolds for nasal cartilage tissue engineering
Autorzy:
Jatteau, S.
Kurowska, A.
Ziąbka, M.
Rajzer, I.
Powiązania:
https://bibliotekanauki.pl/articles/285184.pdf
Data publikacji:
2017
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
electrospinning
tissue engineering scaffolds
nasal cartilages
hyaluronic acid
PCL
Opis:
In this preliminary study, 3D nanofibrous porous scaffolds in the form of spiral tubes for future application as nasal cartilages implants were fabricated by combining polycaprolactone electrospun fibers with drug modified hyaluronic acid gel. It is expected that the spiral form of the scaffold with open geometries, large surface area, and distance between the scaffold walls will be helpful for improving future cell penetration into the scaffolds, nutrient transport and metabolic waste removal, which are otherwise limited in conventional electrospun tissue-engineered scaffolds. The tubular scaffolds structure, its porosity and fibers’ diameter were assessed via scanning electron microscopy, and biological properties of the scaffolds were evaluated in an in vitro study using Simulated Body Fluid (SBF). SEM results showed that apatite formed within a short period on tubular scaffolds after its immersion in SBF, demonstrating high in vitro bioactivity of the scaffolds.
Źródło:
Engineering of Biomaterials; 2017, 20, 141; 8-12
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The vitamin B1 release from collagen, chitosan and hyaluronic acid blends
Autorzy:
Kaczmarek, B.
Sionkowska, A.
Bladzich, A.
Powiązania:
https://bibliotekanauki.pl/articles/286151.pdf
Data publikacji:
2016
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
natural polymers
biomedical materials
vitamins
Źródło:
Engineering of Biomaterials; 2016, 19, 138; 44
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characterization of chitosan, collagen, hyaluronic acid blends crosslinked by tannic acid addition
Autorzy:
Sionkowska, A.
Kaczmarek, B.
Kołodziejczak, A.
Markiewicz, E.
Powiązania:
https://bibliotekanauki.pl/articles/285687.pdf
Data publikacji:
2016
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
biopolymers
biomaterials
tannic acid
Źródło:
Engineering of Biomaterials; 2016, 19, 138; 43
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The penetration of topically applied ointment containing hyaluronic acid in rabbit tissues
Autorzy:
Birkenfeld, B.
Parafiniuk, M.
Bielecka-Grzela, S.
Klimowicz, A.
Piwowarska-Bilska, H.
Mikolajczak, R.
Listewnik, M.H.
Kurzejamska-Parafiniuk, M.
Osowski, A.
Byszewska-Szpocinska, E.
Powiązania:
https://bibliotekanauki.pl/articles/30258.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The properties of hyaluronic acid used for treatment of acute and chronic joint disease are known for many years and this compound is widely used both in humans and animals. To obtain a therapeutic effect of a certain drug, the appropriate concentration in the target organ or tissue is important. The application of labeled compounds is one of the frequently applied techniques to estimate drug penetration into the skin and other body tissues or organs. The aim of the study was to evaluate the penetration of hyaluronic acid labeled with I-131 through the skin and its distribution within the knee joint and other internal organs in rabbits after a topical application of an ointment containing hyaluronic acid.The experiment was performed on 22 albino rabbits divided into control and examined groups. Fifteen rabbits were exposed to the multicomponent ointment containing hyaluronic acid labeled with I-131. Time of exposure was 48 hours. Hyaluronate penetrated to a high degree into the examined tissues. No significant differences in terms of leg tissue activity were observed between a leg tissue exposed to labeled ointment and that unexposed, suggesting that after topical administration, the active component of the ointment is delivered to the joint via the blood stream. Hyaluronate applied topically penetrates through the skin into the rabbit tissues and organs and into the joint fluid of both legs (exposed and not exposed). This route of administration seems to be useful for this drug delivery and allows to avoid unnecessary side effects.
Źródło:
Polish Journal of Veterinary Sciences; 2011, 14, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of serum hyaluronic acid determination in the diagnosis of liver fibrosis
Autorzy:
Gudowska, Monika
Cylwik, Bogdan
Chrostek, Lech
Powiązania:
https://bibliotekanauki.pl/articles/1038585.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
hyaluronic acid
extracellular matrix
non-invasive marker
cirrhosis
fibrosis
hepatitis
Opis:
The common pathway leading to liver fibrosis and cirrhosis is growing deposition of extracellular matrix (ECM). It results from molecular and histological rearrangement of collagens, glycoproteins and hyaluronans. Hyaluronic acid is a chief component of the extracellular matrix of connective tissues and plays the main structural role in the formation of ECM. The most important organ involved in the synthesis of hyaluronic acid is the liver. In this paper the meaning of hyaluronic acid in the diagnostics of liver diseases is discussed. Here, we focus on the described changes of hyaluronic acid concentration in the pathological processes of the liver, including alcoholic and non-alcoholic liver diseases. The results of published clinical studies have shown its high diagnostic sensitivity, which probably enables its application in laboratory diagnosis.
Źródło:
Acta Biochimica Polonica; 2017, 64, 3; 451-457
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł

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