Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "antimicrobial compounds" wg kryterium: Temat

  Lista filtrów
Wyrównaj
    Wyświetlanie 1-4 z 4
    Tytuł:
    Synergistic Antimicrobial Effect of Raspberry (Rubus idaeus L., Rosaceae) Preparations and Probiotic Bacteria on Enteric Pathogens
    Autorzy:
    Bauza-Kaszewska, Justyna
    Żary-Sikorska, Ewa
    Gugolek, Andrzej
    Ligocka, Anna
    Kosmala, Monika
    Karlińska, Elżbieta
    Fotschki, Bartosz
    Juśkiewicz, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1363279.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
    Tematy:
    raspberry
    bioactive compounds
    antimicrobial properties
    pathogenic bacteria
    probiotic Lactobacillus
    Opis:
    Due to the increasing microbial tolerance to commonly used food preservatives, as well as growing consumer awareness of their adverse impact on human health, alternative methods of pathogens reduction in food are widely investigated. The aim of this research was to examine the antimicrobial activity of red raspberry pomace and seed preparations against enterohemorrhagic Escherichia coli (EHEC), Salmonella Typhimurium, Salmonella Enteritidis, Listeria monocytogenes, and probiotic Lactobacillus rhamnosus strain. The combined action of LAB (lactic acid bacteria) and raspberry preparations on the pathogenic species was also evaluated. The results of our study showed no or weak antibacterial effect of raspberry preparations on the pathogenic bacteria tested. Regardless of preparation concentration (1.0 or 2.0 mg/mL), the bacteria number after 48-h incubation was usually higher than in the culture at the initial stage and varied from 105 to 107 cfu/mL. On the other hand, probiotic Lactobacillus rhamnosus strain caused a significant reduction in the enteric pathogen count after 24-h co-culture with LAB. The concentrations of both Salmonella serotypes were below the detection limit of the analytical methods applied. Moreover, the combined use of LAB and raspberry preparations resulted in the total elimination of Salmonella strains and the reduction in L. monocytogenes number from 105 to 102 -104 cfu/mL after 24-h co-culture. EHEC revealed the highest resistance to the mixed culture effect. The synergic antimicrobial effect suggests the possibility of applying probiotic bacteria and berry preparations as natural antimicrobial agents in the food industry.
    Źródło:
    Polish Journal of Food and Nutrition Sciences; 2021, 71, 1; 51-59
    1230-0322
    2083-6007
    Pojawia się w:
    Polish Journal of Food and Nutrition Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    TOTAL PHENOLIC AND FLAVONOID CONTENTS, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF SELECTED HONEYS AGAINST HUMAN PATHOGENIC BACTERIA
    Autorzy:
    Živković, Jelena
    Sunarić, Slavica
    Stanković, Nemanja
    Mihajilov-Krstev, Tatjana
    Spasić, Ana
    Powiązania:
    https://bibliotekanauki.pl/articles/895587.pdf
    Data publikacji:
    2019-08-30
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    honey
    antioxidant activity
    antimicrobial activity
    phenolic compounds
    colour intensity
    Opis:
    The study analyzed colour intensity, the total phenolic and flavonoid contents, as well as antioxidant and antibacterial activities of honeys from Serbia. All the tested honeys contained considerable levels of phenolics. The highest phenolic content was obtained in forest honey - 1389.71 mg gallic acid equivalents/kg. High levels of phenolics and flavonoids were also determined in honeydew, meadow and oregano honeys. The radical scavenging activity measured by DPPH method in linden and forest honey was 0.45 and 2.75 mmol Trolox equivalents/kg, respectively. The ferric reducing potential was the greatest in forest honey - 6.04 mmol Fe2+/kg. Darker honeys had a greater phenolic content and antioxidant activity. The antimicrobial activity of honeys against six bacterial strains isolated from human material were studied using a microwell dilution assay. The minimal inhibitory concentration of honeys ranged from 6.25% w/w (for oregano honey against Enterococcus faecalis and honeydew honey against Streptococcus pneumoniae) to >50% w/w (meadow honey against Staphylococcus aureus). The minimal bactericidal concentration ranged from 12.5% w/w (honeydew and bee pollen enriched honey against E. faecalis) to >50% w/w. Higher values of antimicrobial activities were found in honeydew, oregano, and forest honeys, while meadow honey showed the lowest antimicrobial activity. Analyzed honeys exhibited a strong antioxidant and broad-spectrum antibacterial activity against multidrug-resistant pathogenic bacteria. Phenolic compounds, especially in dark amber forest and honeydew honey, as well as in amber oregano honey, may contribute to their efficacy in therapeutic administration.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 4; 671-681
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Aminokwasy, glikany, peptydy i białka w ścieżkach diagnostycznych i terapeutycznych chorób cywilizacyjnych XXI wieku : projektowanie i charakterystyka fizykochemiczna oraz strukturalna
    Amino acids, glycans, peptides and proteins in the diagnostic and therapeutic pathways of the 21st century civilization diseases : design, physicochemical and structural characterisation
    Autorzy:
    Bylińska, Irena
    Dzierżyńska, Maria
    Giżyńska, Małgorzata
    Guzow, Katarzyna
    Jankowska, Elżbieta
    Jurczak, Przemysław
    Kaczyński, Zbigniew
    Karska, Natalia
    Kowalczyk, Agnieszka
    Kuncewicz, Katarzyna
    Orlikowska, Marta
    Sawicka, Justyna
    Spodzieja, Marta
    Szpakowska, Nikola
    Szymańska, Aneta
    Wieczerzak, Ewa
    Witkowska, Julia
    Rodziewicz-Motowidło, Sylwia
    Powiązania:
    https://bibliotekanauki.pl/articles/2200549.pdf
    Data publikacji:
    2022
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    fluorophores
    fluorescence spectroscopy
    antimicrobial activity
    anticancer activity
    Cystapep
    Stahylococcus aureus
    antimicrobial compounds
    amyloidogenic protein
    mutagenesis
    fibrilization
    proteasome
    aging
    neurodegeneration
    self-assembling peptides
    tissue engineering
    biomaterials
    immune checkpoints
    peptide inhibitors
    immunotherapy
    ligands of TAP protein
    viral diseases
    NMR structure of the UL49.5 protein
    glycans
    glycoconjugates
    fluorofory
    spektroskopia fluorescencyjna
    aktywność przeciwdrobnoustrojowa
    aktywność antynowotworowa
    Staphylococcus aureus
    związki przeciwbakteryjne
    białko amyloidogenne
    mutageneza
    fibrylizacja
    proteasom
    procesy starzeniowe
    neurodegeneracja
    peptydy samoorganizujące
    inżynieria tkankowa
    biomateriały
    punkty kontrolne układu immunologicznego
    inhibitory peptydowe
    immunoterapia
    ligandy białka TAP
    choroby wirusowe,
    struktura NMR białka UL49.5
    glikany
    glikokoniugaty
    Opis:
    The civilization diseases of the 21st century are non-infectious disorders, affecting a large part of modern society. They are associated with the significant development of industry and technology, and hence with environmental pollution and an unhealthy lifestyle. These factors have led to the development of many civilization diseases, which currently include: cardiovascular diseases, respiratory diseases, diabetes, obesity, malignant tumors, gastrointestinal diseases, mental disorders and allergic diseases. The development of technologies, including modern therapies and new drugs, resulted in increase in life expectancy. This creates a global problem of an aging population with an increasing number of diseases of the old age, i.e. dementias. In addition, sedentary lifestyles and changing diets are the reasons why more and more people develop metabolic diseases, as well as neurological and cognitive disorders characterized by progressive damage to nerve cells and dementia. Currently, problem on a global scale is also the growing resistance to existing antimicrobial drugs. Therefore, the scientists face many challenges related to searching for the causes of these diseases, their diagnosis and treatment. Scientific research conducted at the Department of Biomedical Chemistry at the Faculty of Chemistry of the University of Gdańsk is part of this research trend. In this publication, we discuss various research topics with the long-term aim of solving the problems associated with the diseases mentioned above. The following chapters are dedicated to (i) looking for new effective fluorophores with diagnostic and anti-cancer activity; (ii) designing of new compounds with antibacterial and antiviral activity and their synthesis; (iii) investigating the mechanisms of amyloid deposit formation by human cystatin C and possibilities of inhibition of this process; (iv) designing and studies of compounds activating the proteasome with the potential to suppress the development of neurodegenerative diseases; (v) designing peptide fibrils and hydrogels as drug carriers; (vi) searching for peptide inhibitors of immune checkpoint as potential drugs for immunotherapy; (vii) studying the mechanism of action of selected herpesviruses by determining the structure of viral proteins and (viii) studying the composition of natural glycans and glycoconjugates in order to better understand the mechanisms of interaction of bacteria with the environment or with the host.
    Źródło:
    Wiadomości Chemiczne; 2022, 76, 5-6; 393--431
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pharmaceuticals and personal care products in the environment with emphasis on horizontal transfer of antibiotic resistance genes
    Autorzy:
    Prasad, Majeti N. V.
    Elchuri, Sailaja V.
    Powiązania:
    https://bibliotekanauki.pl/articles/2175231.pdf
    Data publikacji:
    2022
    Wydawca:
    Towarzystwo Chemii i Inżynierii Ekologicznej
    Tematy:
    antimicrobial resistance
    bacterial resistance
    PPCPs
    pharmaceutical active compounds
    PhACs
    flow routes
    flow through food chain
    treatment technologies
    waste water treatment plant
    odporność na antybiotyki
    oporność bakterii
    związki farmaceutyczne
    drogi przepływu
    łańcuch żywnościowy
    technologie oczyszczania
    rośliny oczyszczające ścieki
    Opis:
    Pharmaceuticals and personal care products (PPCPs) discharged into environment has several adverse impacts. PPCPs are widely utilised for veterinary as well as cosmetic and personal health reasons. These are members of the expanding class of substances known as Contaminants of Emerging Concern (CECs). Antibiotic resistance in the environment and garbage generated by PPCP endanger life. The World Health Organisation (WHO) now recognises antibiotic resistance as a significant global health problem due to the expected increase in mortality caused by it. In the past ten years, mounting data has led experts to believe that the environment has a significant impact on the development of resistance. For human diseases, the external environment serves as a source of resistance genes. It also serves as a major pathway for the spread of resistant bacteria among various habitats and human populations. Large-scale DNA sequencing methods are employed in this thesis to better comprehend the dangers posed by environmental antibiotic resistance. The quantification of the number is an important step in this process. Metagenomic measurement of the number of antibiotic resistance genes in various contexts is a crucial step in this process. However, it’s also crucial to put this data into a broader context by integrating things like taxonomic information, antibiotic concentrations, and the genomic locations of found resistance genes.
    Źródło:
    Chemistry-Didactics-Ecology-Metrology; 2022, 27, 1-2; 35--51
    2084-4506
    Pojawia się w:
    Chemistry-Didactics-Ecology-Metrology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

      Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies